Best TWAS P=5.68e-08 · Best GWAS P=3.53e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | RP11-422P24.10 | 0.03 | 0.02 | enet | 7 | 0.01 | 0.0138 | -5.3 | 5.4 | 5.7e-08 | -0.97 | 0.03 | 0.94 | TRUE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | SLC39A1 | 0.02 | 0.02 | blup | 35 | 0.02 | 0.0024 | -5.3 | -5.4 | 8.4e-08 | 0.98 | 0.02 | 0.87 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SLC39A1 | 0.02 | 0.02 | blup | 35 | 0.01 | 0.0302 | -5.5 | -5.3 | 1.1e-07 | 0.99 | 0.01 | 0.71 | FALSE |