Best TWAS P=1.39e-08 · Best GWAS P=5.89e-08 conditioned to 0.000144
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TAOK1 | 0.06 | 0.00 | bslmm | 370 | 0.02 | 2.1e-03 | 4.2 | 5.7 | 1.4e-08 | 0.32 | 0.08 | 0.34 | TRUE |
| 2 | GTEx | Brain Cortex | GOSR1 | 0.20 | 0.20 | enet | 7 | 0.18 | 1.4e-05 | 5.0 | 5.3 | 1.0e-07 | 0.96 | 0.02 | 0.97 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | CPD | 0.04 | 0.00 | lasso | 3 | 0.03 | 4.4e-03 | -5.1 | -5.4 | 6.5e-08 | -0.96 | 0.06 | 0.66 | FALSE |
| 4 | GTEx | Heart Left Ventricle | ANKRD13B | 0.13 | 0.04 | lasso | 5 | 0.03 | 1.5e-02 | 3.4 | 5.4 | 8.4e-08 | 0.28 | 0.36 | 0.30 | FALSE |
| 5 | GTEx | Nerve Tibial | GOSR1 | 0.13 | 0.11 | lasso | 3 | 0.11 | 5.7e-08 | 5.1 | 5.1 | 2.7e-07 | 0.99 | 0.02 | 0.98 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | GOSR1 | 0.06 | 0.11 | enet | 7 | 0.10 | 6.8e-12 | 5.3 | 5.2 | 1.8e-07 | 0.99 | 0.01 | 0.99 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GOSR1 | 0.02 | 0.00 | blup | 56 | 0.01 | 4.8e-02 | 5.3 | 5.1 | 3.0e-07 | 0.99 | 0.02 | 0.71 | FALSE |