Hub : Genes

ANKRD13B

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.1440 0.0480 1.8e-07 0.145 NA 0.115 NA 0.152 6.8e-12 NA 1.1e-09 NA 2.0e-12
2 GTEx Heart Atrial Appendage 0.1370 0.0790 5.2e-03 0.095 NA 0.110 NA 0.087 4.9e-05 NA 1.2e-05 NA 9.9e-05
3 GTEx Heart Left Ventricle 0.1269 0.0608 1.0e-04 0.039 NA 0.021 NA 0.026 3.8e-03 NA 2.7e-02 NA 1.5e-02
4 GTEx Lung 0.1278 0.0503 9.0e-07 0.090 NA 0.069 NA 0.083 2.0e-07 NA 5.4e-06 NA 6.8e-07
5 GTEx Skin Sun Exposed Lower leg 0.0800 0.0400 6.6e-05 0.043 NA 0.053 NA 0.058 1.6e-04 NA 3.2e-05 NA 1.4e-05
6 GTEx Thyroid 0.2280 0.0680 6.7e-09 0.123 NA 0.171 NA 0.175 1.1e-09 NA 4.4e-13 NA 2.3e-13
7 METSIM Adipose 0.0361 0.0152 6.1e-07 0.034 0.043 0.045 0.041 0.047 7.3e-06 3.7e-07 2.0e-07 7e-07 1.4e-07
8 TCGA Thyroid Carcinoma 0.1360 0.0390 1.8e-15 0.195 0.169 0.190 NA 0.192 1.2e-18 3.0e-16 3.3e-18 NA 2.2e-18

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 2.8 4.5 9.2 -2.9 -3.0 0.3 -2.8 -1.6 0.4 -2.5 1.2
Bipolar Disorder or Schizophrenia 1.4 3.4 5.9 -1.9 -2.2 -0.9 -2.3 -1.9 1.2 -2.4 1.3
Depressed Affect (Nagel 2018) 0.8 1.7 2.8 1.4 1.5 0.3 1.7 1.6 -0.9 1.6 -0.9
Depression (Nagel 2018) 0.2 0.3 0.8 0.2 0.9 -0.2 0.6 0.8 -0.5 0.2 -0.4
Intelligence (Savage-Jansen 2018) 4.2 13.0 28.7 2.2 0.2 5.4 2.7 4.3 -3.8 3.3 -4.3
Neuroticism (Nagel 2018) 0.6 1.3 2.8 1.6 1.2 0.3 1.7 1.4 -0.4 1.1 -0.5
Schizophrenia (2018) 0.5 1.0 2.5 -0.1 -0.4 -1.6 -0.8 -1.2 1.3 -1.1 0.8
Schizophrenia vs Biploar Disorder 1.2 1.6 3.9 2.0 1.5 0.7 1.6 0.8 -0.2 1.1 -1.3
Worry (Nagel 2018) 0.1 0.1 0.3 0.6 -0.6 0.4 0.4 -0.2 -0.0 0.0 0.2
Alzheimer’s Disease (in mother) 1.9 2.2 5.8 -0.5 -0.6 -0.5 -1.2 -2.4 2.0 -1.6 1.7
Alzheimer’s Disease (in father) 0.9 1.0 2.4 0.1 0.5 -1.5 -0.2 -0.9 1.4 -0.7 1.6
Alzheimer’s Disease (including proxy) 4.0 5.8 9.9 -1.4 -1.4 -1.5 -2.3 -3.1 3.0 -2.6 3.0
Crohns Disease (2017) 0.5 1.1 3.7 1.2 0.5 0.3 0.8 -0.4 1.9 0.0 1.5
Irritable Bowel Disease (IBD) 0.8 1.9 4.8 2.2 1.2 0.5 1.9 1.3 0.7 1.5 -0.5
Ulcerative Colitis (UC) 2.2 4.2 7.4 2.7 1.9 0.3 2.6 2.2 -0.5 2.6 -1.9
Major Depression (MDD) 1.2 1.4 3.4 -1.5 -0.5 -0.7 -1.7 -0.9 0.9 -1.8 0.4
Reaction Time 0.5 0.9 2.5 -1.6 -1.5 -0.5 -0.7 -0.8 -0.7 -0.1 -1.0
Verbal and Numeric Reasoning (VNR) 2.6 6.3 21.7 0.7 -0.9 4.7 1.1 2.8 -2.7 2.0 -2.7
Breast Cancer 1.5 3.6 8.3 1.7 1.3 2.9 1.1 2.9 -1.3 1.0 -2.0
Ovarian Cancer 0.3 0.5 2.6 -0.2 -0.6 -1.6 0.1 -0.1 0.6 -0.4 0.4
Prostate Cancer 0.2 0.3 1.1 1.1 0.3 0.7 0.5 0.1 -0.2 0.3 -0.2
Age at First Birth 1.1 1.5 3.5 1.7 1.2 0.9 1.9 0.4 0.2 1.8 -0.3
Bipolar Disorder (2011) 7.3 7.1 13.3 -2.9 -3.6 -1.6 -3.4 -2.5 2.1 -3.2 0.0
Body Mass Index (BMI) (2010) 0.4 0.5 2.2 -0.8 -1.5 -0.7 -0.0 -0.6 -0.4 0.1 -0.5
Coronary Artery Disease (CAD) 3.2 3.8 6.9 2.0 1.7 1.4 2.0 2.6 -1.9 2.2 -1.5
Crohns Disease (2012) 0.7 1.2 3.8 -0.0 -0.1 -1.0 -0.3 -0.9 1.9 -0.7 1.7
Mean Putamen Volume 1.3 1.5 2.1 1.1 1.0 0.3 1.4 1.4 -1.4 1.2 -1.4
Fasting Glucose 2.5 3.0 7.8 -0.7 -2.2 -0.6 -1.7 -2.8 0.1 -2.1 1.7
HbA1C 0.4 0.5 1.6 1.2 0.5 -0.3 0.9 -0.8 -0.4 0.2 0.5
HDL Cholesterol 1.4 2.3 3.8 -0.8 -0.7 -1.3 -2.0 -1.2 1.8 -2.0 1.8
LDL Cholesterol 1.2 1.9 4.7 1.2 1.6 1.4 1.3 2.2 -0.9 1.3 -0.7
Lupus 0.7 1.1 2.3 -1.5 -1.3 -0.7 -1.0 -1.3 -0.8 -0.8 -0.6
Neuroticism (2016) 0.1 0.2 0.4 0.5 0.3 -0.4 0.6 0.1 0.5 0.3 0.3
Primary Biliary Cirrhosis 0.5 0.7 1.6 -0.2 -0.3 -1.1 -0.5 -1.3 0.7 -0.7 1.1
Rheumatoid Arthritis 0.3 0.3 1.1 0.1 0.1 0.2 0.3 1.1 -0.6 0.6 -0.9
Schizophrenia (2014) 0.1 0.3 1.0 0.2 0.1 -0.2 -0.3 -0.7 1.0 -0.7 0.1
Triglycerides 0.0 0.1 0.1 0.1 -0.3 0.4 0.2 -0.3 0.2 -0.3 0.3
Type 2 Diabetes (T2D) (2012) 2.5 2.9 5.1 1.1 1.1 1.6 2.1 1.7 -1.2 2.3 -2.0
Ulcerative Colitis 0.8 1.2 4.4 0.3 0.0 2.1 0.5 1.3 -0.7 0.6 -1.6
Blood Eosinophil Count 0.3 1.9 6.0 -1.1 -1.5 0.5 -0.4 1.9 -2.5 0.0 -1.4
Blood Platelet Count 10.1 116.6 327.6 18.1 8.3 16.4 9.3 10.0 -2.7 7.8 -3.6
Blood Red Count 2.8 27.3 42.6 2.8 2.1 5.6 4.6 6.4 -6.0 5.8 -6.5
Blood White Count 5.1 38.1 71.2 -4.3 -4.2 -5.6 -5.5 -7.8 5.6 -6.7 8.4
Heel T-Score 6.3 49.8 130.0 -0.1 0.0 -3.2 -6.0 -5.9 11.4 -7.7 11.3
BMI 2.7 15.5 41.0 1.4 1.2 1.2 3.3 4.9 -6.4 4.3 -5.0
Height 4.0 76.6 201.6 -8.9 -14.2 0.8 -9.8 -9.3 3.6 -9.3 7.0
Waist Hip Ratio (WHR) 0.1 0.4 2.1 0.8 -0.0 1.4 -0.3 0.8 -0.1 -0.4 -0.1
Systolic Blood Pressure 0.5 2.3 10.2 -0.2 -1.0 3.2 -0.0 0.3 -2.2 0.5 -1.3
Smoking Status 0.4 1.1 2.3 -0.4 1.3 -1.5 -0.3 -0.4 0.9 -1.1 1.5
Allergy or Eczema 1.9 5.1 8.0 2.8 1.7 2.8 2.7 2.4 -1.4 2.1 -1.7
Cardiovascular Disease 3.7 12.3 26.3 1.5 1.2 2.4 3.2 4.0 -5.1 4.2 -4.3
Hypothyroidism (self reported) 3.5 8.0 27.0 0.8 0.3 0.0 2.3 2.0 -5.2 2.9 -4.3
Respiratory disease 0.1 0.3 0.9 0.2 0.5 -0.9 -0.0 -0.8 0.1 -0.8 0.3
Type 2 Diabetes (T2D) (2018) 0.9 1.8 3.7 1.9 0.6 1.0 1.8 0.9 -1.0 1.3 -1.5
Lung FEV1/FVC ratio 19.7 100.1 171.6 5.1 4.6 9.3 9.0 11.9 -11.1 12.2 -13.1
Lung FVC 1.3 6.8 22.2 0.5 2.9 -1.1 -1.2 -0.6 4.7 -2.5 3.8
Neuroticism 0.1 0.4 0.9 0.8 0.6 -0.1 0.6 0.4 0.7 0.1 0.9
Chronotype (morning person) 0.9 2.0 5.4 -2.3 -2.2 -1.2 -1.0 -1.0 -0.9 -0.7 -1.1
Hair Pigment 0.4 10.0 13.9 -3.5 -2.7 -3.0 -3.6 -2.0 3.2 -3.7 3.3
Tanning 0.5 5.5 12.6 -3.5 -2.7 -1.0 -3.1 -2.6 0.3 -2.6 0.6
Hand grip strength (left) 1.3 3.4 8.1 -2.4 -2.8 0.2 -2.7 -1.1 0.7 -1.9 1.0
Number of treatments/medications taken 1.7 3.0 7.0 0.5 0.8 0.1 1.6 1.9 -2.6 1.8 -2.6
Average weekly spirits intake 0.9 1.1 2.8 -0.9 -0.2 -0.2 -1.2 -0.6 1.7 -1.2 1.4
Sensitivity / hurt feelings 0.7 1.2 3.0 -0.4 -0.4 -1.7 -0.6 -0.5 1.4 -1.2 1.4
Frequency of depressed mood in last 2 weeks 0.1 0.2 0.6 -0.3 0.3 -0.2 0.2 0.3 -0.8 -0.0 -0.7
Hearing difficulty/problems: Yes 2.0 3.0 8.5 1.8 2.9 0.9 1.7 2.1 -0.1 1.8 -0.9
Relative age of first facial hair 0.4 0.8 3.6 0.5 0.6 -1.9 0.5 1.3 0.5 0.4 -0.1
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 3.5 0.3 1.5 -1.9 1.2 0.1 -1.3 0.8 -0.8
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.4 0.8 0.2 -1.2 0.4 -0.1 0.7 -0.0 0.9
Ever had hysterectomy (womb removed) 0.6 0.7 2.5 0.1 0.6 0.7 0.2 0.1 -1.3 -0.5 -1.6
Systolic blood pressure, automated reading 0.5 1.3 6.1 0.9 -0.1 0.7 0.9 -0.0 -2.5 1.0 -1.1
Eye problems/disorders: Diabetes related eye disease 0.1 0.2 1.0 0.1 -0.5 1.0 0.0 0.2 -0.1 -0.1 0.0
Angina 5.8 7.6 17.2 1.4 1.3 0.3 2.8 3.2 -4.1 3.2 -3.4
Medication for hormone replacement therapy 0.7 0.8 2.1 -0.7 -0.6 -0.8 -1.0 -0.4 0.9 -1.5 0.8
Vitamin and mineral supplements 0.2 0.3 1.4 0.3 0.0 1.2 0.0 -0.1 0.3 -0.4 0.9
Supplements: Zinc 2.7 2.9 5.2 1.5 1.6 0.1 2.0 2.1 -1.0 1.9 -2.3
Medication: Co-codamol 0.5 0.5 1.4 -1.2 -0.2 -0.4 -0.9 0.1 -0.6 -1.2 0.3
Medication: Metformin 3.4 4.8 8.9 2.8 2.1 1.1 3.0 1.7 -1.5 2.2 -2.4
Diabetes (father) 1.1 1.4 5.4 -1.6 -2.3 0.4 -1.1 -0.8 -0.4 -0.9 -0.6
Diabetes (mother) 1.6 2.0 4.6 1.1 0.2 1.2 1.4 1.1 -2.1 1.6 -1.7
Severe depression (siblings) 0.7 0.8 2.2 1.4 1.3 -1.5 0.8 0.0 -0.5 0.4 -0.2
Pack years adult smoking proportion 1.6 2.5 11.0 -3.3 -1.0 -0.5 -1.8 -1.4 -1.1 -0.9 -0.4
Impedance of leg (right) 0.3 1.2 5.8 1.1 0.5 2.4 1.1 0.6 0.2 0.8 -0.5
Leg fat-free mass (left) 1.0 5.5 17.9 -3.2 -4.2 -0.2 -2.7 -1.4 -1.7 -1.9 0.8
Trunk fat percentage 2.3 9.2 23.4 1.5 0.0 1.2 3.0 3.8 -4.8 3.7 -3.1
Hand grip strength (right) 1.5 4.2 8.9 -2.4 -2.3 -0.2 -3.0 -1.6 1.7 -2.4 1.5
Townsend deprivation index at recruitment 2.8 4.0 12.6 -2.5 0.0 -3.6 -1.6 -1.8 0.9 -1.7 1.8
Current tobacco smoking 0.4 0.6 1.9 -1.4 0.5 0.8 -0.7 0.1 0.6 -0.6 0.9
Average weekly fortified wine intake 1.0 1.2 1.9 -0.7 -1.3 -0.7 -1.4 -0.6 1.1 -1.3 1.3
Maternal smoking around birth 1.2 1.7 4.9 -2.2 -1.3 -0.6 -1.6 -1.1 -0.1 -1.6 0.1
Fed-up feelings 0.1 0.2 0.3 -0.5 -0.5 -0.3 -0.1 0.5 -0.4 0.5 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 0.3 0.4 1.6 -0.3 0.4 -1.3 -0.0 -0.4 -0.7 -0.4 0.5
Relative age voice broke 0.9 1.4 4.2 -0.1 0.2 -2.0 -0.4 -0.7 2.0 -0.8 1.1
Taking other prescription medications 2.9 4.4 7.3 1.3 1.7 0.6 2.4 1.9 -2.6 2.7 -2.5
Age when periods started (menarche) 0.6 1.3 6.0 -0.9 -0.9 -0.4 -0.9 -2.4 0.2 -0.9 1.0
Bilateral oophorectomy (both ovaries removed) 0.5 0.6 2.3 -0.6 -0.1 1.5 -0.5 0.6 -0.3 -0.6 -1.1
Heel bone mineral density (BMD) T-score, automated (left) 4.1 9.2 23.6 0.3 0.2 -3.7 -1.8 -2.9 4.2 -2.6 4.9
Tinnitus: Yes, but not now, but have in the past 2.3 2.4 6.0 1.9 2.4 0.6 2.0 1.5 0.6 1.4 -0.9
Qualifications: CSEs or equivalent 1.3 1.7 3.8 -0.9 -0.6 -0.9 -1.5 -1.9 0.6 -1.5 1.8
Serious illness, injury or assault to yourself 0.6 0.8 2.9 -0.9 0.0 0.4 -0.2 1.2 -1.7 -0.6 -0.8
High blood pressure 3.1 8.8 14.7 2.2 1.3 2.2 3.3 3.4 -3.8 3.6 -2.9
Hayfever, allergic rhinitis or eczema 3.3 7.1 11.5 3.4 2.2 3.3 3.3 2.5 -1.1 2.8 -1.9
Multivitamins +/- minerals 0.9 1.2 2.9 0.5 0.4 -1.1 1.0 0.6 -1.4 1.2 -1.7
Stomach or abdominal pain in last month 3.5 4.4 8.8 1.1 1.0 2.3 1.8 3.0 -2.2 2.2 -2.5
Supplements: Glucosamine 0.3 0.3 2.1 0.2 -1.4 0.5 0.0 -0.5 0.4 0.1 -0.0
Diverticular disease/diverticulitis (self-reported) 0.3 0.4 1.8 -0.3 -0.6 0.2 -0.4 -0.1 -1.3 -0.2 -0.9
Medication: Atenolol 0.8 1.1 2.8 0.2 -0.3 0.5 0.9 1.3 -1.7 1.1 -1.2
Medication: Levothyroxine sodium 0.5 0.8 3.7 -0.3 -0.5 0.2 -0.0 0.6 -1.9 0.5 -1.4
Sitting height 1.8 12.6 29.2 -3.8 -5.4 -0.1 -4.0 -3.9 0.8 -4.2 2.7
Chronic bronchitis/emphysema (father) 0.1 0.1 0.5 -0.2 0.1 -0.1 0.0 -0.6 -0.3 0.3 0.7
High blood pressure (mother) 2.0 2.8 10.4 -0.9 -2.3 -0.2 0.3 1.0 -3.2 1.2 -2.0
Body mass index (BMI) 2.3 9.8 27.7 1.0 1.0 0.4 2.6 4.0 -5.3 3.6 -3.7
Impedance of leg (left) 0.2 0.9 4.0 0.9 0.0 2.0 0.5 -0.2 1.4 -0.1 0.7
Leg predicted mass (left) 1.1 5.8 18.7 -3.2 -4.3 -0.2 -2.8 -1.4 -1.6 -2.0 0.9
Trunk fat mass 1.4 5.8 21.5 0.4 -1.4 1.0 1.7 2.8 -4.6 2.6 -2.3
Waist circumference 1.6 6.0 20.2 0.6 -0.7 1.1 1.9 2.7 -4.5 2.5 -2.9
Number of incorrect matches in round 5.0 8.3 13.2 -2.1 -2.8 -2.6 -2.7 -3.4 1.9 -3.4 3.6
Past tobacco smoking 0.4 0.7 1.5 -1.1 -1.2 0.9 -0.9 -0.7 -0.4 -0.1 -0.7
Alcohol usually taken with meals 0.7 1.2 2.8 0.6 -0.3 -1.4 -0.3 -1.7 1.6 -0.7 1.1
Nervous feelings 0.3 0.6 1.2 1.1 0.0 0.0 0.8 -1.0 0.8 0.4 1.0
Frequency of tenseness / restlessness in last 2 weeks 0.4 0.6 1.6 0.9 0.4 -0.4 1.0 0.4 -1.2 0.5 -0.6
Hearing difficulty/problems with background noise 1.7 2.8 8.3 2.2 2.9 -0.3 1.9 1.4 0.8 1.6 -0.5
Hair/balding pattern: Pattern 2 0.3 0.4 1.7 0.5 0.4 1.3 -0.2 0.2 0.5 -0.1 0.9
Had menopause 1.9 2.4 4.0 1.4 0.5 0.1 1.9 1.3 -2.0 1.9 -1.9
Had other major operations 0.2 0.2 1.1 -0.3 0.1 0.3 0.0 1.0 -0.4 0.2 -0.7
Forced vital capacity (FVC) 5.6 21.4 38.7 -4.0 -3.7 -0.6 -5.6 -4.5 4.6 -6.2 5.5
Heel bone mineral density (BMD) T-score, automated (right) 2.9 6.7 17.2 1.1 0.9 -3.1 -1.0 -2.1 4.0 -1.7 4.1
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.7 -0.3 0.4 0.6 0.4 0.5 -1.2 0.6 -1.3
Qualifications: None of the above 0.4 0.8 1.6 -1.3 0.4 -0.6 -0.9 -0.2 0.9 -1.1 1.0
Financial difficulties in last 2 years 0.4 0.5 1.2 -1.0 -0.8 -1.1 -0.6 0.5 -0.0 -0.4 0.6
Mouth/teeth dental problems 0.6 1.0 4.1 -0.0 -1.3 0.9 -0.7 -2.0 0.2 -0.6 0.1
Heart attack 4.6 5.8 20.2 0.6 0.4 1.3 1.5 2.5 -4.5 1.9 -3.5
Allergy 2.6 5.9 13.0 -3.6 -2.7 -2.5 -3.0 -2.0 0.6 -2.3 1.4
Pain all over the body in last month 0.4 0.5 2.1 -0.5 1.5 0.0 -0.2 -0.0 -1.0 -0.4 -0.4
Diabetes (self-reported) 3.2 5.0 7.0 2.5 1.8 2.0 2.7 2.0 -1.9 2.4 -2.4
Hayfever/allergic rhinitis (self-reported) 2.2 2.9 6.7 2.0 2.6 2.0 1.9 1.3 0.8 1.4 -0.6
Medication: Ramipril 1.0 1.2 3.4 1.4 1.8 -0.4 1.5 0.6 -0.0 1.1 -0.5
Medication: Simvastatin 2.2 3.3 4.6 1.3 1.9 0.2 2.1 2.1 -2.0 2.1 -1.9
Fluid intelligence score 2.3 4.9 11.7 0.8 -0.3 3.4 1.3 2.7 -2.3 2.0 -2.8
Illnesses of siblings 8.5 11.9 23.6 -1.9 -1.5 -2.0 -3.2 -4.2 4.5 -3.8 4.9
Neuroticism score 0.2 0.5 1.1 0.8 0.5 -0.9 0.6 -0.2 0.8 0.1 1.1
Weight 0.7 3.2 10.7 -1.8 -3.2 0.4 -0.8 0.4 -3.3 0.1 -0.7
Impedance of arm (right) 0.4 1.7 6.0 0.6 -0.3 2.2 -0.0 -0.1 2.4 -0.4 1.3
Arm fat percentage (right) 3.4 13.4 26.1 2.1 1.5 1.3 3.7 5.1 -4.9 4.6 -3.7
Trunk fat-free mass 2.0 11.7 32.9 -4.1 -5.7 -0.2 -4.2 -2.9 -0.6 -3.7 2.0
Hip circumference 0.6 2.8 13.2 -1.1 -2.4 -0.4 0.1 0.3 -3.6 0.8 -1.0
Time employed in main current job 0.3 0.3 1.0 0.5 -0.0 -0.8 0.6 0.4 1.0 0.1 0.3
Alcohol intake versus 10 years previously 0.7 1.1 5.9 -0.8 0.4 -0.5 0.4 2.4 -0.3 0.5 -1.0
Father’s age at death 0.8 1.1 2.2 -0.6 -1.4 -0.9 -0.7 -1.5 1.0 -0.7 1.1
Worrier / anxious feelings 0.4 0.7 2.2 1.3 0.9 -0.5 1.5 0.1 0.0 0.9 -0.0
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 1.4 0.3 0.8 0.6 0.7 1.1 -1.2 0.8 -0.5
Falls in the last year 0.5 0.6 2.0 -0.7 0.4 -0.5 -0.6 -0.7 1.0 -0.7 1.4
Hair/balding pattern: Pattern 3 0.1 0.2 0.6 -0.1 -0.6 0.3 -0.2 0.3 -0.7 -0.1 -0.7
Number of live births 0.4 0.6 2.8 1.0 1.7 -0.2 0.9 -0.2 0.1 0.3 0.2
Forced expiratory volume in 1-second (FEV1) 1.1 3.6 6.8 -2.1 -2.0 2.0 -2.6 -0.9 1.2 -2.2 1.4
Pulse rate 0.3 0.6 3.6 -0.6 0.0 1.9 -0.4 0.1 -0.6 -0.2 0.0
Happiness 0.2 0.3 1.3 -0.2 0.6 -1.1 0.4 0.6 0.1 0.0 -0.2
Noisy workplace 1.5 1.8 5.3 -0.4 0.8 -1.6 -0.8 -0.7 2.3 -1.0 1.9
Qualifications: A levels/AS levels or equivalent 0.5 1.0 2.8 1.6 0.5 0.6 1.3 0.1 0.6 1.7 0.1
Serious illness, injury or assault of a close relative in last 2 years 2.4 2.8 5.8 2.0 1.2 2.4 2.1 1.5 -0.4 2.0 -0.7
Mouth/teeth dental problems: Dentures 0.3 0.6 2.7 0.1 1.0 -1.6 0.4 -0.2 -0.6 0.2 0.1
Asthma 0.3 0.7 2.1 0.6 0.5 -1.5 -0.1 -1.1 0.1 -1.0 0.6
Medication: Ibuprofen (e.g. Nurofen) 1.0 1.3 3.7 -1.9 -1.1 0.5 -1.7 -0.8 0.3 -1.1 0.7
Medication: Cholesterol lowering 1.6 2.5 7.3 1.0 0.7 -0.4 1.4 1.7 -2.7 1.5 -1.9
Depression (self-reported) 0.4 0.5 2.0 0.5 0.6 -0.3 0.9 -0.2 -1.4 0.6 -0.6
Medication: Lansoprazole 0.4 0.4 1.1 0.8 -0.2 0.4 0.9 -0.4 -1.0 0.3 -0.7
Prospective memory result 7.1 8.7 11.9 -3.4 -2.7 -3.3 -3.3 -3.2 1.1 -3.4 2.3
Lung cancer (father) 0.4 0.5 2.2 0.4 -0.2 -0.7 0.3 -1.5 -0.5 -0.3 0.7
Illnesses of mother 3.7 4.6 13.8 -0.3 0.6 -1.6 -1.4 -1.9 3.7 -2.1 3.2
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 2.8 5.5 -1.8 -1.9 2.3 -2.2 -0.6 1.1 -1.7 0.8
Pulse wave Arterial Stiffness index 0.1 0.1 0.2 0.1 -0.2 0.4 -0.0 -0.0 0.4 -0.3 0.4
Impedance of arm (left) 0.3 1.2 5.0 0.1 -0.6 0.8 -0.3 -1.1 2.2 -0.7 1.3
Arm fat mass (right) 1.8 7.5 24.3 0.5 -0.5 1.3 1.9 3.5 -4.9 3.0 -3.0
Trunk predicted mass 2.0 11.2 31.9 -4.0 -5.7 -0.2 -4.1 -2.8 -0.7 -3.6 2.0
Standing height 4.3 42.2 86.7 -6.0 -9.3 0.1 -7.3 -7.3 3.8 -7.4 6.2
Length of working week for main job 0.3 0.3 0.8 0.5 0.0 -0.7 -0.2 -0.4 0.5 -0.7 0.9
Exposure to tobacco smoke at home 0.6 0.7 3.2 0.3 0.7 -0.6 -0.1 -0.3 0.9 -0.4 1.8
Breastfed as a baby 1.6 2.0 4.1 1.7 2.0 -0.8 2.0 0.5 -0.1 1.7 -1.0
Tense / ‘highly strung’ 0.1 0.1 0.3 0.5 0.5 0.1 0.3 -0.3 -0.5 0.1 0.0
Seen doctor (GP) for nerves, anxiety, tension or depression 1.7 2.5 6.1 1.6 2.5 1.4 1.9 1.3 -1.0 1.4 -1.2
Hair/balding pattern: Pattern 4 0.1 0.2 0.6 -0.3 0.6 -0.6 -0.3 0.7 -0.1 -0.2 0.5
Birth weight of first child 1.3 2.4 6.4 -0.1 -0.7 -1.4 -1.4 -1.3 2.1 -1.6 2.5
Peak expiratory flow (PEF) 2.9 6.6 15.9 0.5 -0.5 4.0 1.1 3.2 -2.8 2.6 -3.2
Pulse wave reflection index 0.1 0.1 0.2 -0.3 0.2 0.3 0.1 0.5 0.4 0.4 0.1
Ever highly irritable/argumentative for 2 days 0.4 0.5 1.4 0.2 0.9 -1.2 0.5 1.2 0.4 0.1 0.3
Loud music exposure frequency 0.2 0.2 0.7 0.3 0.5 0.4 -0.2 -0.4 0.8 -0.3 0.5
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 2.9 1.7 1.1 0.4 1.2 0.7 -0.1 1.1 0.2
Mouth/teeth dental problems: Bleeding gums 1.3 1.6 2.8 -1.7 -1.1 0.4 -1.6 0.4 1.3 -1.4 1.6
Blood clot in the leg (DVT) 3.1 4.0 6.1 1.9 1.2 1.8 1.9 2.5 -2.1 2.3 -2.2
Medication: Paracetamol 0.3 0.4 1.9 -0.6 -0.3 0.3 -0.4 1.4 -0.8 -0.3 -0.5
Headache pain in last month 0.3 0.5 1.9 -1.4 -1.0 -0.0 -0.6 0.1 0.2 -0.6 -0.1
Medication for cholesterol, blood pressure or diabetes 4.2 6.9 10.9 -1.9 -1.4 -0.7 -3.0 -3.1 3.3 -3.3 3.0
Glaucoma (self-reported) 0.4 0.5 1.2 0.5 0.0 -0.2 1.1 -0.0 -0.9 0.8 -1.1
Gout (self-reported) 0.7 1.0 3.8 0.3 -0.5 2.0 0.8 -0.4 -1.1 1.0 -0.8
Hypothyroidism/myxoedema (self-reported) 2.2 4.3 14.9 0.6 0.4 -0.1 1.6 1.3 -3.9 2.2 -3.1
Medication: Amlodipine 1.6 2.2 5.6 0.2 -0.0 -0.3 1.7 0.9 -2.4 2.1 -1.9
Medication: Ventolin 100micrograms inhaler 0.3 0.3 1.1 0.6 0.6 -1.1 0.3 -0.7 0.5 -0.3 0.2
Birth weight 3.4 7.3 15.2 -3.2 -3.9 -2.6 -2.9 -2.8 1.7 -2.1 1.5
Chronic bronchitis/emphysema (mother) 0.6 0.7 2.0 -0.3 0.4 1.0 0.6 0.9 -1.4 0.4 -1.2
High blood pressure (siblings) 6.0 8.6 18.3 1.5 0.9 1.4 2.7 3.5 -3.9 3.3 -4.3
Forced vital capacity (FVC), Best measure 5.2 19.0 33.2 -3.9 -3.8 -0.6 -5.4 -4.4 4.2 -5.8 4.9
Body fat percentage 3.3 13.0 28.4 2.1 0.9 1.4 3.7 4.5 -5.3 4.5 -3.7
Leg fat percentage (right) 5.4 19.4 41.1 2.5 2.1 1.7 4.3 5.4 -6.4 5.5 -4.8
Arm fat-free mass (right) 1.4 7.0 20.5 -3.4 -4.5 -0.8 -2.9 -2.2 -1.9 -2.3 0.9
Exposure to tobacco smoke outside home 0.4 0.6 2.8 -0.6 0.0 1.7 -0.5 0.8 -0.3 -0.6 -0.0
Comparative body size at age 10 0.5 1.3 3.7 0.6 0.4 0.9 0.8 1.2 -1.7 1.0 -1.9
Number of full brothers 0.3 0.4 1.1 0.1 1.0 -0.1 0.3 0.5 0.9 -0.2 0.8
Worry too long after embarrassment 0.9 1.5 4.2 0.3 -0.2 -0.7 -0.4 -1.5 1.6 -1.5 2.0
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.4 5.2 1.7 2.3 -0.7 1.3 0.0 0.6 0.5 0.2
Wheeze or whistling in the chest in last year 0.8 1.4 4.0 -0.4 0.8 -1.3 0.6 1.1 -2.0 0.6 -1.6
Number of children fathered 0.6 0.7 3.5 0.4 0.5 1.9 0.1 0.5 -0.6 0.4 -0.8
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 0.5 0.2 0.7 -0.7 0.2 0.2 0.5 0.3 -0.3
Age at first live birth 1.5 2.6 4.8 2.2 1.6 1.0 1.8 1.8 -0.2 2.0 -1.3
Pulse wave peak to peak time 0.1 0.1 0.3 -0.5 -0.4 -0.3 -0.5 -0.4 -0.2 -0.2 -0.1
Health satisfaction 1.8 2.3 4.5 1.6 1.0 0.4 2.1 1.2 -1.7 1.7 -1.6
Shortness of breath walking on level ground 0.3 0.4 1.2 -1.1 -0.5 0.6 -0.6 1.1 -0.2 -0.3 -0.0
Qualifications: College or University degree 0.6 2.0 6.1 2.5 1.5 0.3 1.3 0.4 1.9 1.2 0.5
Eye problems/disorders: None of the above 0.2 0.2 0.7 -0.3 0.4 0.8 -0.4 0.7 0.3 -0.0 -0.4
Mouth/teeth dental problems: Loose teeth 0.6 0.8 2.2 -1.5 -1.0 -0.6 -0.9 -0.3 -0.3 -1.0 0.7
Emphysema/chronic bronchitis 0.3 0.4 0.9 -0.9 -0.6 1.0 -0.4 -0.5 -0.2 -0.6 -0.0
Medication for pain relief, constipation, heartburn 0.9 1.5 5.7 0.6 0.3 0.4 -0.3 -1.2 2.4 -0.8 1.8
Neck or shoulder pain in last month 0.8 1.1 3.1 -0.4 0.0 0.8 0.6 0.8 -1.8 0.9 -1.7
Medication: Blood pressure 4.0 7.1 13.5 1.7 1.2 0.9 3.2 2.4 -3.7 3.6 -3.1
Angina (self-reported) 5.4 7.1 17.1 1.3 1.1 0.3 2.6 3.0 -4.1 3.0 -3.3
Migraine (self-reported) 1.2 1.5 4.2 -0.5 0.4 -0.1 -0.9 -1.2 1.9 -1.3 2.1
Medication: Ibuprofen 1.0 1.2 3.0 -1.7 -1.3 0.5 -1.5 -1.0 -0.2 -1.2 0.5
Medication: Allopurinol 1.3 1.7 3.7 0.6 0.0 1.9 1.4 0.2 -1.9 1.7 -1.0
Medication: Omeprazole 0.6 0.7 1.6 0.4 1.3 -1.1 1.0 0.2 -0.7 1.0 -0.6
Medication: Seretide 50 evohaler 0.6 0.6 1.6 -1.3 -0.9 -0.3 -1.0 -0.3 0.7 -1.0 -0.2
Mean time to correctly identify matches 0.5 0.9 2.6 -0.5 -1.0 -0.4 0.3 0.3 -1.4 1.0 -1.6
Heart disease (mother) 2.5 3.0 9.1 0.1 0.1 1.1 0.7 3.0 -2.7 1.6 -1.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.3 0.3 0.6 -0.5 -0.8 0.2 -0.7 -0.7 -0.5 -0.6 -0.1
Whole body fat mass 1.7 7.2 26.2 0.5 -0.8 1.0 2.0 3.1 -5.1 2.9 -2.9
Leg fat mass (right) 3.0 11.5 35.4 1.1 0.2 1.5 2.8 4.0 -5.9 3.9 -3.8
Arm predicted mass (right) 1.3 6.5 19.1 -3.2 -4.4 -0.8 -2.9 -2.1 -1.7 -2.3 1.0
Pulse rate, automated reading 0.2 0.7 2.3 -0.9 -0.0 1.5 -1.0 -0.4 0.4 -0.8 0.8
Alcohol intake frequency. 2.1 4.9 14.4 -3.8 -2.1 -2.3 -2.4 -1.7 -0.3 -2.2 1.1
Comparative height size at age 10 4.4 24.0 56.7 -5.2 -7.5 0.5 -5.5 -5.2 2.4 -5.3 4.2
Number of full sisters 0.1 0.1 0.3 -0.3 0.5 0.0 -0.1 -0.1 0.1 -0.3 -0.2
Suffer from ‘nerves’ 0.2 0.4 1.1 0.6 -0.3 -1.1 0.5 -0.5 0.5 0.2 0.9
Overall health rating 1.4 3.0 6.6 1.2 1.8 -1.2 2.6 1.2 -1.9 2.1 -1.2
Chest pain or discomfort 5.8 8.3 14.7 1.7 2.8 1.4 3.1 3.8 -3.1 2.9 -3.4
Had major operations 0.2 0.2 0.6 0.5 0.1 -0.8 0.5 -0.1 0.1 0.4 0.3
Age at last live birth 0.3 0.4 1.6 0.6 0.7 -1.3 0.4 0.1 0.4 0.2 0.4
Family relationship satisfaction 0.6 0.7 2.7 -0.5 -0.6 0.4 0.4 1.6 -0.9 0.5 -1.1
Leg pain on walking 0.2 0.3 1.3 -0.5 0.2 0.5 0.1 -0.0 -1.2 -0.2 -0.3
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.3 0.8 -0.9 -0.1 0.7 -0.7 -0.6 -0.1 -0.6 -0.2
Commuting to job workplace: Car/motor vehicle 0.1 0.1 0.5 -0.1 -0.5 0.0 -0.7 -0.1 0.1 -0.3 0.6
Illness, injury, bereavement, stress in last 2 years 0.4 0.5 1.6 0.1 -0.4 -0.7 -0.3 -1.3 0.9 -0.4 0.8
Medication: Aspirin 5.1 6.7 13.5 1.4 1.1 0.7 2.4 3.3 -3.5 2.9 -3.7
Supplements: Vitamin C 0.3 0.4 1.0 -0.5 -0.6 0.3 0.1 0.9 -0.5 0.7 -1.0
Knee pain experienced in last month 2.5 3.8 6.4 1.6 0.5 2.0 2.2 1.9 -2.5 2.4 -1.8
Hypertension (Self-reported) 3.2 8.9 15.7 1.9 1.0 2.5 3.0 3.7 -4.0 3.5 -3.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.5 1.7 4.4 2.1 1.4 -0.2 2.1 0.5 -0.7 1.5 -0.5
Illnesses of father: Heart disease 3.1 4.3 7.7 2.1 2.3 2.1 1.8 2.8 -1.4 1.7 -2.1
Illnesses of siblings: Diabetes 0.1 0.1 0.3 -0.3 0.1 -0.2 -0.2 -0.5 0.2 -0.4 0.2
Smoking status: Previous 0.3 0.4 2.5 0.6 0.3 -1.6 0.4 0.3 -0.0 -0.2 0.4
Forced expiratory volume in 1-second (FEV1), predicted 4.4 9.2 18.1 -2.8 -4.3 -0.9 -3.3 -4.0 1.5 -3.0 2.9
Whole body fat-free mass 1.7 9.5 28.5 -3.9 -5.3 -0.3 -3.7 -2.4 -1.1 -3.1 1.6
Leg fat-free mass (right) 1.5 8.2 22.9 -3.7 -4.8 -0.6 -3.5 -2.2 -0.5 -2.8 1.9
Arm fat percentage (left) 3.3 13.1 26.7 2.0 1.4 0.6 3.6 4.7 -5.2 4.7 -3.8
Average weekly red wine intake 0.1 0.1 0.5 0.3 -0.2 0.2 -0.3 -0.1 0.7 -0.4 0.3
Handedness (chirality/laterality): Left-handed 0.2 0.2 0.7 0.8 -0.6 0.2 -0.1 -0.4 0.8 -0.2 0.1
Mood swings 0.8 1.4 3.5 0.4 1.1 0.4 1.5 1.9 -0.8 1.6 -0.9
Loneliness, isolation 0.5 0.7 2.1 0.9 0.6 -1.5 1.2 0.5 -0.6 0.7 -0.4
Long-standing illness, disability or infirmity 0.6 1.0 1.8 1.1 1.3 -0.2 1.3 1.1 -1.1 0.8 -0.1
Ever had bowel cancer screening 4.7 5.5 10.1 3.2 2.6 1.6 3.0 2.4 -0.9 2.5 -1.6
Diabetes diagnosed by doctor 2.4 3.9 6.3 2.4 1.3 1.8 2.5 1.9 -1.4 2.1 -2.1
Ever had stillbirth, spontaneous miscarriage or termination 0.5 0.5 1.8 -0.5 -0.1 -0.6 -0.6 -0.5 1.3 -0.7 0.7
Friendships satisfaction 0.4 0.4 1.4 0.2 0.8 0.1 0.6 1.2 -0.4 0.3 -0.9
Qualifications: nursing, teaching 1.2 1.8 3.6 1.7 1.6 0.5 1.9 0.9 -0.2 1.9 -0.9
Commuting to job workplace: Walk 0.8 0.8 2.0 1.0 1.0 1.4 1.1 0.3 -0.8 0.7 -0.5
Eye problems/disorders: Cataract 1.3 1.5 2.8 1.5 1.2 0.5 1.7 1.2 -0.9 1.7 -0.7
Mouth/teeth dental problems: Mouth ulcers 1.9 3.0 6.4 2.1 2.5 -1.0 2.3 1.4 0.1 1.9 -1.1
Medication for cholesterol 1.0 1.6 3.6 -0.0 -0.2 -1.0 -0.7 -1.6 1.9 -1.0 1.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 0.9 3.7 -0.1 -0.2 0.5 0.2 0.4 -1.9 0.6 -1.6
Back pain experienced in last month 3.4 5.0 15.5 0.3 -0.0 0.2 1.7 1.7 -3.9 2.3 -3.6
Mineral and other dietary supplements 0.3 0.4 1.3 -0.3 0.3 1.1 -0.5 -0.3 0.3 -0.6 1.0
Breast cancer (self-reported) 1.3 1.6 3.2 -1.8 -1.3 -1.3 -1.3 -1.2 0.4 -1.4 1.1
Asthma (self-reported) 0.3 0.5 1.8 0.6 0.7 -1.3 0.1 -0.8 -0.1 -0.9 0.2
Osteoporosis (self-reported) 0.7 0.9 3.1 1.4 1.8 0.0 1.0 0.7 0.0 0.7 0.2
Osteoarthritis (self-reported) 1.2 1.6 3.0 -0.6 -0.8 -1.2 -1.2 -1.7 0.4 -1.7 1.6
Medication: Aspirin 5.2 6.7 11.8 1.7 1.4 0.6 2.6 3.2 -3.4 3.0 -3.4
Medication: Gliclazide 1.9 2.1 6.2 1.7 0.8 2.5 1.2 1.4 -1.3 0.9 -1.2
Illnesses of father: None of the above (group 1) 1.8 2.2 5.6 -0.8 -0.7 -0.8 -1.2 -1.5 1.9 -1.6 2.4
Smoking status: Current 0.4 0.6 1.3 -1.2 0.7 0.7 -0.6 -0.1 0.8 -0.7 1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 1.5 0.6 0.6 1.2 0.5 0.8 -0.2 0.6 -1.2
Whole body water mass 1.6 9.1 26.6 -3.8 -5.2 -0.5 -3.6 -2.4 -1.0 -3.0 1.6
Leg predicted mass (right) 1.5 8.2 22.8 -3.6 -4.8 -0.6 -3.5 -2.3 -0.5 -2.8 1.9
Arm fat mass (left) 1.8 7.2 24.5 0.4 -0.4 0.6 1.9 3.3 -4.9 2.9 -3.0
Number of self-reported non-cancer illnesses 6.3 11.0 15.4 2.8 2.6 1.6 3.9 3.4 -3.9 3.9 -3.7
Average weekly champagne plus white wine intake 1.2 1.7 3.4 1.8 0.8 -0.8 1.8 1.3 0.1 1.8 -0.9
Miserableness 0.9 1.5 4.4 1.6 2.1 -0.8 1.6 0.7 0.2 1.3 0.0
Guilty feelings 0.4 0.5 2.3 0.8 0.8 -1.5 0.7 -0.4 0.3 0.2 0.3
Wears glasses or contact lenses 1.0 1.2 3.1 1.3 -0.0 -0.1 1.8 0.2 -1.1 1.1 -1.4
Ever taken oral contraceptive pill 1.0 1.2 3.7 -0.7 -1.2 -1.9 -0.6 -1.4 0.5 -0.5 0.9
Hearing aid user 0.8 0.9 3.1 1.0 0.6 1.8 0.2 -0.5 0.8 -0.4 1.1
Mother’s age at death 0.2 0.3 1.0 0.6 0.2 0.0 0.7 0.3 -0.5 1.0 -0.3
Financial situation satisfaction 0.2 0.2 0.7 -0.4 -0.7 -0.8 -0.3 -0.2 -0.1 -0.3 0.3
Tinnitus: Yes, now most or all of the time 0.5 0.5 1.2 -1.1 0.1 -1.1 -1.0 0.9 -0.0 -0.4 0.0
Commuting to job workplace: Public transport 0.2 0.3 1.2 0.1 0.3 0.7 0.5 -1.1 0.5 0.3 0.1
Eye problems/disorders: Glaucoma 0.3 0.4 1.5 -0.5 -0.8 -0.7 0.0 -1.2 0.0 -0.4 0.1
Medication: Blood pressure 0.9 1.6 2.7 0.5 0.2 1.4 1.2 1.6 -1.6 1.4 -1.4
Pain type(s) experienced in last month: Hip pain 2.4 3.1 10.1 0.2 0.6 1.1 1.1 2.1 -3.2 1.6 -2.2
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.6 0.0 -0.9 -1.3 0.1 -0.2 -0.6 0.3 -0.5
High cholesterol (Self-reported) 2.7 4.9 10.4 1.7 1.8 0.4 2.4 3.2 -1.9 2.7 -2.3
Medication: Bendroflumethiazide 0.6 0.9 2.0 1.0 0.7 0.8 1.3 1.4 0.2 1.1 0.0
Medication: Paracetamol 0.2 0.2 0.7 -0.3 -0.4 0.2 -0.5 0.8 -0.4 -0.7 -0.2
Medication: Lisinopril 2.1 2.7 4.7 1.1 0.7 1.8 1.9 0.9 -2.0 2.2 -1.9
Medication: Atorvastatin 1.1 1.4 4.7 0.6 -0.4 0.3 0.8 1.2 -1.6 1.0 -2.2
Illnesses of father: High blood pressure 1.9 2.3 3.8 1.3 1.1 0.5 1.7 1.9 -1.5 2.0 -1.6
Alcohol drinker status: Never 0.1 0.2 0.4 -0.4 0.6 -0.5 0.1 -0.3 0.6 -0.2 0.1
Ever smoked 0.8 1.4 4.1 1.6 2.0 -0.3 1.5 1.1 0.5 0.8 0.5
Basal metabolic rate 1.3 7.1 23.6 -3.5 -4.9 -0.2 -3.1 -1.7 -1.5 -2.3 1.1
Leg fat percentage (left) 3.9 14.0 31.4 2.1 1.5 1.2 3.7 4.6 -5.6 4.7 -3.9
Arm fat-free mass (left) 1.1 5.7 18.4 -3.1 -4.3 -0.1 -2.6 -1.4 -2.0 -2.1 0.7
Number of operations (self-reported) 1.1 1.7 6.2 0.6 1.0 1.0 1.2 2.5 -0.8 1.2 -1.2
Average weekly beer plus cider intake 0.7 1.0 2.7 0.9 1.6 -1.0 1.3 0.4 0.2 1.2 -0.2
Irritability 1.6 2.6 5.6 0.2 -0.1 1.5 1.1 2.2 -2.4 1.6 -2.1
Risk taking 0.3 0.4 0.9 -0.9 0.3 -0.2 -0.4 1.0 -0.6 -0.4 -0.9
Ever had prostate specific antigen (PSA) test 0.9 1.0 2.4 1.6 0.4 -0.0 1.2 0.6 -0.5 1.5 -1.0
Fractured/broken bones in last 5 years 1.8 2.3 6.2 0.6 0.7 0.8 1.6 0.9 -2.5 1.7 -2.1
Age started oral contraceptive pill 1.1 1.4 2.6 1.5 1.3 -0.3 1.6 1.4 -0.6 1.4 -0.8
Diastolic blood pressure, automated reading 0.9 2.8 12.0 -0.2 -0.4 1.2 0.5 1.3 -3.5 1.2 -2.4
Ever depressed for a whole week 0.1 0.2 0.5 0.1 0.7 0.3 0.2 0.3 -0.1 0.2 -0.7
Unable to work because of sickness or disability 1.2 1.5 3.5 -1.5 -0.5 -1.4 -1.0 -1.9 0.2 -1.6 0.8
Commuting to job workplace: Cycle 0.5 0.6 2.6 -0.1 0.7 0.9 0.0 1.6 0.4 0.1 -0.7
Myopia 0.3 0.5 1.5 0.4 1.2 0.5 0.7 1.0 0.7 0.4 -0.2
Vascular/heart problems diagnosed by doctor 3.5 9.5 16.6 -1.9 -1.5 -2.0 -3.1 -3.9 4.1 -3.8 3.3
Cholesterol lowering medication 10.2 15.0 27.0 2.5 2.6 2.2 3.9 4.7 -4.2 4.5 -5.2
Medication: Omeprazole (e.g. Zanprol) 0.1 0.2 1.1 0.1 0.3 -1.1 0.2 0.0 -0.3 0.1 0.0
Pain experienced in last month 3.1 5.2 10.4 -0.5 -1.0 -1.7 -2.1 -2.5 3.2 -2.6 3.1
Supplements: Calcium 2.4 2.6 5.2 2.0 2.3 -1.7 1.9 1.4 0.2 1.8 -0.6
Basal cell carcinoma (self-reported) 1.7 2.0 4.2 -2.0 -1.5 -0.7 -2.0 -0.7 0.7 -2.0 0.2
Heart attack/myocardial infarction (self-reported) 4.1 5.3 18.6 0.6 0.3 1.3 1.4 2.4 -4.3 1.8 -3.3
Deep venous thrombosis (DVT) (self-reported) 3.0 3.9 5.4 2.0 1.1 1.8 1.9 2.3 -2.1 2.3 -2.0
Heart disease (siblings) 6.7 8.2 15.4 2.1 3.0 -0.0 3.1 3.9 -3.0 3.1 -2.9
Alcohol drinker status: Previous 1.0 1.1 3.6 -1.3 0.2 -1.9 -0.8 -0.6 0.4 -1.0 1.1
Pack years of smoking 1.6 2.3 10.0 -3.2 -1.1 -0.6 -1.6 -1.0 -1.5 -0.7 -0.8
Impedance of whole body 0.2 1.0 3.4 0.9 -0.0 1.6 0.5 -0.4 1.8 -0.2 0.8
Leg fat mass (left) 2.3 9.0 29.9 0.8 -0.1 1.2 2.3 3.5 -5.5 3.4 -3.2
Arm predicted mass (left) 1.2 5.9 19.8 -3.1 -4.5 0.5 -2.8 -1.2 -2.0 -2.1 0.5