Best TWAS P=1.56e-09 · Best GWAS P=5.94e-10 conditioned to 0.127
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Glioblastoma Multiforme | JUND | 0.17 | 0.00 | blup | 57 | 0.03 | 0.0545 | -3.7 | -5.3 | 1.1e-07 | 0.27 | 0.00 | 0.01 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | JUND | 0.11 | 0.03 | blup | 58 | 0.04 | 0.0014 | 3.6 | -5.8 | 8.8e-09 | 0.24 | 0.00 | 0.06 | TRUE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | MAST3 | 0.02 | 0.02 | lasso | 3 | 0.01 | 0.0147 | -5.8 | 6.0 | 1.6e-09 | -0.92 | 0.01 | 0.91 | TRUE |
4 | The Cancer Genome Atlas | Thyroid Carcinoma | MAST3 | 0.04 | 0.02 | lasso | 2 | 0.00 | 0.3360 | -5.8 | 6.0 | 1.6e-09 | -0.92 | 0.01 | 0.91 | FALSE |