Best TWAS P=2.28e-12 · Best GWAS P=1.64e-12 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | NLRC5 | 0.38 | 0.24 | lasso | 4 | 0.30 | 5.0e-23 | -6.5 | 6.3 | 3.1e-10 | -0.65 | 0.06 | 0.94 | FALSE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CETP | 0.05 | 0.03 | enet | 10 | 0.03 | 2.7e-04 | -5.7 | 5.5 | 3.1e-08 | -0.67 | 0.04 | 0.91 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | CETP | 0.21 | 0.19 | lasso | 3 | 0.18 | 2.6e-10 | -6.5 | 6.9 | 4.7e-12 | -0.81 | 0.04 | 0.96 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | CETP | 0.06 | 0.04 | lasso | 1 | 0.04 | 2.8e-05 | -7.0 | 7.0 | 2.3e-12 | -0.99 | 0.00 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CETP | 0.07 | 0.08 | lasso | 1 | 0.07 | 7.8e-08 | -7.0 | 7.0 | 2.3e-12 | -0.99 | 0.00 | 1.00 | FALSE |