[Hub]/) : Traits : LDL Cholesterol : ← →

chr16:71,349,498-72,845,749

Best TWAS P=3.58e-23 · Best GWAS P=1.75e-22 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DHX38 0.31 0.39 enet 41 0.41 3.2e-54 4.3 5.5 3.3e-08 0.73 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex HPR 0.72 0.60 lasso 7 0.61 6.9e-94 9.8 9.9 3.6e-23 1.00 0.00 1.00 TRUE
3 CommonMind Brain Pre-frontal Cortex TXNL4B 0.05 0.07 lasso 3 0.06 8.8e-08 9.8 9.1 9.3e-20 0.97 0.00 1.00 FALSE
4 GTEx Brain Cortex DHODH 0.21 0.06 enet 14 0.05 1.5e-02 4.3 5.7 1.3e-08 0.81 0.01 0.90 FALSE
5 METSIM Adipose DHX38 0.08 0.06 lasso 7 0.09 4.5e-13 -5.5 5.6 1.8e-08 0.54 1.00 0.00 FALSE
6 NTR Blood DHX38 0.02 0.01 blup 355 0.02 6.5e-06 -4.1 6.2 4.9e-10 0.45 0.86 0.09 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme HPR 0.82 0.49 lasso 3 0.47 3.4e-16 9.8 9.9 5.5e-23 1.00 0.00 1.00 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma DHX38 0.02 0.01 blup 62 0.01 1.7e-02 -4.1 5.9 2.7e-09 0.48 0.04 0.41 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma HP 0.60 0.42 lasso 5 0.41 3.8e-50 9.8 9.7 2.5e-22 1.00 0.00 1.00 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma HPR 0.75 0.56 lasso 4 0.56 6.1e-76 9.8 9.7 3.3e-22 1.00 0.00 1.00 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma TXNL4B 0.44 0.29 lasso 4 0.29 3.2e-33 9.8 9.8 1.1e-22 0.99 0.00 1.00 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma HP 0.05 0.04 blup 53 0.04 9.8e-05 4.4 -5.5 4.4e-08 -0.66 0.43 0.53 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma HP 0.52 0.13 lasso 5 0.22 1.9e-21 -6.1 8.1 7.7e-16 0.12 1.00 0.00 TRUE