499 significantly associated models · 154 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 24871730 | 26855401 | 7 | 2 | 2.3e-12 | 1.9e-10 | 2.9e-01 | 97 | LDLRAP1 TMEM50A |
2 | 1 | 54527647 | 56375280 | 2 | 1 | 6.3e-13 | 1.9e-28 | 3.3e-22 | 23 | USP24 |
3 | 1 | 61510619 | 63844736 | 3 | 1 | 6.1e-18 | 2.6e-18 | 1.0e+00 | 100 | DOCK7 |
4 | 1 | 92277843 | 93942442 | 1 | 1 | 4.9e-08 | 1.5e-07 | 2.4e-01 | 95 | EVI5 |
5 | 1 | 108654479 | 111016796 | 18 | 8 | 3.9e-172 | 9.7e-171 | 1.0e+00 | 100 | AMIGO1 GSTM1 PSRC1 RP5-1065J22.8 SORT1 STXBP3 TMEM167B |
6 | 2 | 20062043 | 21958745 | 2 | 2 | 6.2e-114 | 4.5e-114 | 1.0e+00 | 100 | APOB HS1BP3 |
7 | 2 | 43302571 | 44735953 | 3 | 2 | 1.1e-14 | 1.7e-47 | 1.6e-31 | 35 | ABCG5 DYNC2LI1 |
8 | 3 | 11900101 | 13321852 | 2 | 1 | 2.4e-08 | 2.2e-07 | 6.7e-02 | 88 | MKRN2 |
9 | 5 | 73626450 | 75704085 | 9 | 1 | 1.7e-41 | 5.1e-45 | 5.7e-06 | 90 | HMGCR |
10 | 6 | 33856903 | 35362848 | 1 | 1 | 3.6e-08 | 4.7e-07 | 4.2e-01 | 98 | C6orf106 |
11 | 6 | 115569351 | 117264735 | 3 | 1 | 2.2e-09 | 2.9e-09 | 1.0e+00 | 100 | FRK |
12 | 6 | 160293151 | 161336020 | 2 | 2 | 6.4e-08 | 1.7e-17 | 1.2e-12 | 30 | LPA SLC22A1 |
13 | 7 | 21336058 | 22188630 | 1 | 1 | 9.4e-10 | 6.9e-10 | 3.4e-02 | 88 | DNAH11 |
14 | 7 | 43885849 | 45318389 | 3 | 4 | 8.0e-09 | 1.0e-09 | NaN | NaN | DDX56 NPC1L1 TMED4 |
15 | 9 | 135629944 | 137034272 | 3 | 1 | 6.2e-30 | 2.3e-21 | 2.1e-03 | 90 | ABO |
16 | 11 | 17923676 | 19345331 | 2 | 1 | 5.2e-08 | 2.9e-07 | 8.9e-01 | 100 | SPTY2D1 |
17 | 11 | 60549966 | 62605067 | 9 | 1 | 1.1e-21 | 1.2e-21 | 1.0e+00 | 100 | TMEM258 |
18 | 11 | 115953897 | 117800682 | 4 | 4 | 4.8e-16 | 1.5e-14 | 2.1e-02 | 91 | BUD13 PAFAH1B2 PCSK7 ZNF259 |
19 | 11 | 125134725 | 126914307 | 3 | 2 | 2.0e-11 | 1.2e-15 | 1.7e-05 | 71 | DCPS ST3GAL4 |
20 | 12 | 111193499 | 113517494 | 7 | 1 | 1.5e-09 | 1.5e-09 | 7.8e-03 | 81 | ALDH2 |
21 | 12 | 120722064 | 122167693 | 3 | 1 | 3.8e-13 | 3.3e-15 | 1.9e-03 | 84 | HNF1A |
22 | 13 | 32275990 | 33700374 | 1 | 1 | 1.5e-07 | 7.5e-08 | 1.4e-01 | 93 | N4BP2L1 |
23 | 14 | 24179343 | 25582885 | 1 | 1 | 3.8e-08 | 4.9e-11 | 2.1e-04 | 68 | NYNRIN |
24 | 16 | 56330832 | 57810318 | 2 | 1 | 2.3e-12 | 1.6e-12 | 1.0e+00 | 100 | CETP |
25 | 16 | 71349498 | 72845749 | 5 | 2 | 3.6e-23 | 1.8e-22 | 1.0e+00 | 100 | HP HPR |
26 | 17 | 26279731 | 27684579 | 1 | 1 | 1.5e-07 | 5.3e-05 | 6.4e-01 | 99 | SDF2 |
27 | 17 | 44788310 | 46474610 | 5 | 1 | 1.3e-11 | 3.9e-09 | 4.2e-02 | 88 | EFCAB13 |
28 | 19 | 9982334 | 12191233 | 12 | 10 | 3.6e-56 | 4.3e-117 | NaN | NaN | CARM1 DOCK6 KANK2 SMARCA4 SPC24 |
29 | 19 | 18333894 | 20451172 | 7 | 1 | 5.0e-20 | 6.7e-22 | 2.9e-03 | 90 | ATP13A1 |
30 | 19 | 44190626 | 46547330 | 16 | 23 | 1.2e-84 | 8.7e-147 | NaN | NaN | APOC1 APOE BCAM BLOC1S3 CEACAM16 CEACAM19 CTB-179K24.3 GEMIN7 KLC3 PVR PVRL2 TOMM40 ZNF229 ZNF285 |
31 | 19 | 48525507 | 49955222 | 4 | 1 | 5.0e-08 | 7.6e-08 | 1.0e+00 | 100 | RASIP1 |
32 | 20 | 39270768 | 40683594 | 4 | 1 | 1.2e-19 | 3.4e-19 | 1.0e+00 | 100 | ZHX3 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Liver | 5 | 0.718 | 3.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 7 | 0.670 | 3.5 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 11 | 0.691 | 2.3 |
GTEx | Whole Blood | 8 | 0.415 | 2.1 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 8 | 0.415 | 2.1 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 7 | 0.362 | 2.0 |
GTEx | Esophagus Mucosa | 13 | 0.402 | 1.9 |
ROSMAP | Brain Pre-frontal Cortex | 19 | 0.443 | 1.9 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 6 | 0.402 | 1.9 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 4 | 0.404 | 1.9 |
GTEx | Muscle Skeletal | 9 | 0.320 | 1.8 |
GTEx | Stomach | 6 | 0.423 | 1.8 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 3 | 0.289 | 1.8 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 3 | 0.310 | 1.8 |
GTEx | Brain Hippocampus | 2 | 0.392 | 1.7 |
GTEx | Pancreas | 6 | 0.376 | 1.7 |
GTEx | Pituitary | 5 | 0.455 | 1.7 |
GTEx | Skin Sun Exposed Lower leg | 13 | 0.368 | 1.7 |
GTEx | Spleen | 7 | 0.507 | 1.7 |
NTR | Blood | 11 | 0.461 | 1.7 |
YFS | Blood | 9 | 0.197 | 1.7 |
CommonMind | Brain Pre-frontal Cortex | 23 | 0.436 | 1.7 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 18 | 0.443 | 1.7 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 3 | 0.462 | 1.7 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 2 | 0.415 | 1.7 |
GTEx | Adrenal Gland | 7 | 0.492 | 1.6 |
GTEx | Artery Tibial | 12 | 0.329 | 1.6 |
GTEx | Brain Cerebellar Hemisphere | 4 | 0.275 | 1.6 |
GTEx | Brain Cortex | 2 | 0.199 | 1.6 |
GTEx | Breast Mammary Tissue (Male) | 4 | 0.345 | 1.6 |
GTEx | Cells Transformed fibroblasts | 21 | 0.514 | 1.6 |
GTEx | Colon Sigmoid | 3 | 0.210 | 1.6 |
GTEx | Colon Transverse | 6 | 0.300 | 1.6 |
GTEx | Heart Atrial Appendage | 2 | 0.130 | 1.6 |
GTEx | Ovary | 4 | 0.451 | 1.6 |
GTEx | Skin Not Sun Exposed Suprapubic | 5 | 0.208 | 1.6 |
GTEx | Small Intestine Terminal Ileum | 2 | 0.442 | 1.6 |
GTEx | Uterus | 3 | 0.541 | 1.6 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 13 | 0.313 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 13 | 0.336 | 1.6 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 12 | 0.433 | 1.6 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 6 | 0.381 | 1.6 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 24 | 0.549 | 1.6 |
The Cancer Genome Atlas | Thyroid Carcinoma | 15 | 0.307 | 1.6 |
GTEx | Adipose Subcutaneous | 8 | 0.236 | 1.5 |
GTEx | Adipose Visceral Omentum | 5 | 0.253 | 1.5 |
GTEx | Artery Aorta | 7 | 0.242 | 1.5 |
GTEx | Artery Coronary | 1 | 0.087 | 1.5 |
GTEx | Brain Cerebellum | 4 | 0.207 | 1.5 |
GTEx | Brain Frontal Cortex BA9 | 1 | 0.111 | 1.5 |
GTEx | Brain Hypothalamus | 2 | 0.349 | 1.5 |
GTEx | Brain Putamen basal ganglia | 1 | 0.165 | 1.5 |
GTEx | Breast Mammary Tissue | 2 | 0.104 | 1.5 |
GTEx | Breast Mammary Tissue (Female) | 3 | 0.190 | 1.5 |
GTEx | Cells EBV-transformed lymphocytes | 2 | 0.145 | 1.5 |
GTEx | Esophagus Gastroesophageal Junction | 1 | 0.071 | 1.5 |
GTEx | Esophagus Muscularis | 10 | 0.318 | 1.5 |
GTEx | Nerve Tibial | 11 | 0.261 | 1.5 |
GTEx | Prostate | 2 | 0.246 | 1.5 |
GTEx | Testis | 9 | 0.292 | 1.5 |
GTEx | Thyroid | 10 | 0.258 | 1.5 |
GTEx | Vagina | 0 | 0.000 | 1.5 |
METSIM | Adipose | 16 | 0.354 | 1.5 |
The Cancer Genome Atlas | Esophageal Carcinoma | 2 | 0.308 | 1.5 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 10 | 0.389 | 1.5 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 9 | 0.380 | 1.5 |
GTEx | Brain Caudate basal ganglia | 1 | 0.111 | 1.4 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.4 |
GTEx | Heart Left Ventricle | 3 | 0.203 | 1.4 |
GTEx | Lung | 3 | 0.107 | 1.4 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 2 | 0.129 | 1.4 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 3 | 0.239 | 1.4 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 5 | 0.418 | 1.4 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.2 |