Best TWAS P=1.29e-09 · Best GWAS P=3.29e-08 conditioned to 0.0287
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | UHRF1BP1 | 0.32 | 0.26 | enet | 33 | 0.33 | 1.3e-12 | 4.2 | 5.4 | 8.0e-08 | 0.39 | 0.18 | 0.82 | FALSE |
2 | GTEx | Esophagus Muscularis | TAF11 | 0.13 | 0.02 | lasso | 6 | 0.00 | 1.6e-01 | 5.4 | -6.1 | 1.3e-09 | -0.61 | 0.02 | 0.60 | TRUE |
3 | GTEx | Heart Left Ventricle | UHRF1BP1 | 0.23 | 0.12 | lasso | 7 | 0.22 | 1.2e-11 | 4.3 | 5.5 | 3.7e-08 | 0.36 | 0.22 | 0.78 | FALSE |
4 | GTEx | Muscle Skeletal | UHRF1BP1 | 0.34 | 0.34 | enet | 45 | 0.39 | 4.3e-40 | 4.2 | 5.3 | 1.2e-07 | 0.40 | 0.74 | 0.26 | FALSE |
5 | GTEx | Skin Not Sun Exposed Suprapubic | UHRF1BP1 | 0.20 | 0.10 | enet | 30 | 0.15 | 2.1e-08 | 4.0 | 5.7 | 9.9e-09 | 0.33 | 0.18 | 0.82 | FALSE |
6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UHRF1BP1 | 0.06 | 0.05 | blup | 70 | 0.04 | 8.6e-06 | 5.1 | 5.4 | 5.3e-08 | 0.31 | 0.03 | 0.97 | TRUE |