222 significantly associated models · 57 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 190521054 | 192254289 | 4 | 2 | 3.1e-18 | 9.7e-66 | 1.4e-53 | 19 | MFSD6 NAB1 |
2 | 3 | 57622089 | 59105913 | 2 | 1 | 1.8e-08 | 1.3e-07 | 6.3e-01 | 99 | PXK |
3 | 4 | 102093807 | 103243101 | 1 | 1 | 2.4e-07 | 4.5e-10 | 9.0e-05 | 60 | BANK1 |
4 | 6 | 34065982 | 35552627 | 2 | 2 | 1.3e-09 | 3.3e-08 | 2.9e-02 | 84 | TAF11 UHRF1BP1 |
5 | 7 | 127812871 | 129502461 | 6 | 10 | 1.5e-44 | 3.8e-45 | NaN | NaN | ATP6V1F IRF5 RP11-286H14.6 TSPAN33 |
6 | 8 | 10265712 | 11891593 | 6 | 6 | 2.7e-16 | 5.2e-18 | NaN | NaN | AF131215.2 AF131215.9 BLK FAM167A |
7 | 11 | 198510 | 1423176 | 10 | 2 | 1.6e-12 | 3.5e-11 | 2.4e-02 | 88 | HRAS TMEM80 |
8 | 11 | 34189564 | 35949179 | 2 | 2 | 2.4e-11 | 2.9e-11 | 9.8e-01 | 100 | APIP CD44 |
9 | 12 | 128579481 | 130007356 | 1 | 1 | 2.1e-08 | 1.0e-07 | 4.8e-03 | 72 | SLC15A4 |
10 | 16 | 30154740 | 31957368 | 7 | 7 | 1.4e-32 | 1.8e-46 | NaN | NaN | BCL7C HSD3B7 ITGAD ITGAM MIR4519 |
11 | 17 | 37363793 | 38783469 | 4 | 1 | 8.1e-10 | 5.3e-07 | 9.1e-01 | 100 | IKZF3 |
12 | 19 | 1473344 | 2923263 | 1 | 1 | 2.7e-07 | 3.8e-06 | 1.2e-01 | 89 | DOT1L |
13 | 19 | 9755448 | 11146499 | 2 | 2 | 3.0e-08 | 1.5e-12 | 9.6e-08 | 43 | ICAM3 ICAM5 |
14 | 22 | 21075537 | 22685340 | 4 | 1 | 4.1e-15 | 8.3e-14 | 3.2e-01 | 98 | CCDC116 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Artery Coronary | 2 | 0.170 | 1.8 |
GTEx | Brain Putamen basal ganglia | 1 | 0.162 | 1.8 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 3 | 0.435 | 1.8 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.7 |
GTEx | Heart Atrial Appendage | 3 | 0.191 | 1.7 |
GTEx | Small Intestine Terminal Ileum | 2 | 0.440 | 1.7 |
GTEx | Spleen | 2 | 0.143 | 1.7 |
GTEx | Whole Blood | 5 | 0.252 | 1.7 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 5 | 0.245 | 1.7 |
GTEx | Adipose Visceral Omentum | 6 | 0.296 | 1.6 |
GTEx | Adrenal Gland | 3 | 0.208 | 1.6 |
GTEx | Brain Cortex | 1 | 0.097 | 1.6 |
GTEx | Brain Frontal Cortex BA9 | 1 | 0.109 | 1.6 |
GTEx | Breast Mammary Tissue (Male) | 1 | 0.084 | 1.6 |
GTEx | Cells EBV-transformed lymphocytes | 1 | 0.071 | 1.6 |
GTEx | Colon Sigmoid | 2 | 0.138 | 1.6 |
GTEx | Colon Transverse | 2 | 0.098 | 1.6 |
GTEx | Esophagus Muscularis | 6 | 0.187 | 1.6 |
GTEx | Heart Left Ventricle | 1 | 0.066 | 1.6 |
GTEx | Liver | 1 | 0.141 | 1.6 |
GTEx | Ovary | 3 | 0.332 | 1.6 |
GTEx | Pancreas | 4 | 0.246 | 1.6 |
GTEx | Pituitary | 1 | 0.090 | 1.6 |
GTEx | Skin Sun Exposed Lower leg | 4 | 0.111 | 1.6 |
GTEx | Uterus | 0 | 0.000 | 1.6 |
GTEx | Vagina | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 4 | 0.242 | 1.6 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 2 | 0.183 | 1.6 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 3 | 0.295 | 1.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 2 | 0.182 | 1.6 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 4 | 0.242 | 1.6 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 1 | 0.094 | 1.6 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 1 | 0.188 | 1.6 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 1 | 0.079 | 1.6 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 2 | 0.396 | 1.6 |
GTEx | Adipose Subcutaneous | 4 | 0.115 | 1.5 |
GTEx | Artery Aorta | 7 | 0.236 | 1.5 |
GTEx | Artery Tibial | 4 | 0.107 | 1.5 |
GTEx | Brain Caudate basal ganglia | 1 | 0.110 | 1.5 |
GTEx | Brain Cerebellar Hemisphere | 0 | 0.000 | 1.5 |
GTEx | Brain Cerebellum | 4 | 0.203 | 1.5 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.5 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.5 |
GTEx | Breast Mammary Tissue | 2 | 0.102 | 1.5 |
GTEx | Cells Transformed fibroblasts | 2 | 0.048 | 1.5 |
GTEx | Esophagus Gastroesophageal Junction | 2 | 0.139 | 1.5 |
GTEx | Esophagus Mucosa | 5 | 0.151 | 1.5 |
GTEx | Lung | 3 | 0.105 | 1.5 |
GTEx | Muscle Skeletal | 3 | 0.104 | 1.5 |
GTEx | Nerve Tibial | 5 | 0.116 | 1.5 |
GTEx | Prostate | 1 | 0.121 | 1.5 |
GTEx | Skin Not Sun Exposed Suprapubic | 5 | 0.204 | 1.5 |
GTEx | Stomach | 0 | 0.000 | 1.5 |
GTEx | Testis | 4 | 0.127 | 1.5 |
GTEx | Thyroid | 6 | 0.151 | 1.5 |
METSIM | Adipose | 9 | 0.196 | 1.5 |
NTR | Blood | 3 | 0.125 | 1.5 |
ROSMAP | Brain Pre-frontal Cortex | 6 | 0.137 | 1.5 |
YFS | Blood | 4 | 0.087 | 1.5 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 9 | 0.205 | 1.5 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 3 | 0.146 | 1.5 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 3 | 0.110 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 6 | 0.147 | 1.5 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 6 | 0.140 | 1.5 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 1 | 0.034 | 1.5 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 3 | 0.120 | 1.5 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 3 | 0.189 | 1.5 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 1 | 0.076 | 1.5 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 7 | 0.152 | 1.5 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 4 | 0.238 | 1.5 |
The Cancer Genome Atlas | Thyroid Carcinoma | 9 | 0.175 | 1.5 |
GTEx | Breast Mammary Tissue (Female) | 2 | 0.123 | 1.4 |
CommonMind | Brain Pre-frontal Cortex | 5 | 0.093 | 1.4 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.4 |