[Hub]/) : Traits : Neuroticism (2016) :

chr11:46,686,260-48,559,571

Best TWAS P=4.19e-08 · Best GWAS P=2.27e-07 conditioned to 0.0392

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts FNBP4 0.11 0.05 lasso 8 0.08 1.6e-06 4.6 -5.1 3.0e-07 -0.70 0.10 0.89 FALSE
2 GTEx Esophagus Gastroesophageal Junction NUP160 0.18 0.02 enet 18 0.11 7.1e-05 2.6 -5.3 1.4e-07 -0.55 0.11 0.57 FALSE
3 GTEx Esophagus Muscularis MTCH2 0.09 0.04 lasso 6 0.02 1.8e-02 -4.7 -5.5 4.2e-08 -0.66 0.12 0.78 TRUE
4 GTEx Liver C1QTNF4 0.25 0.14 enet 16 0.20 2.3e-06 -3.7 5.3 1.2e-07 0.83 0.07 0.86 FALSE
5 GTEx Testis C1QTNF4 0.14 0.12 lasso 4 0.11 1.6e-05 4.7 5.2 1.8e-07 0.74 0.06 0.92 FALSE
6 YFS Blood SPI1 0.65 0.18 enet 75 0.27 1.6e-87 -3.9 5.3 1.3e-07 0.26 0.56 0.38 FALSE
7 The Cancer Genome Atlas Prostate Adenocarcinoma NUP160 0.03 0.02 enet 7 0.02 6.3e-03 -4.3 -5.2 2.4e-07 -0.69 0.04 0.57 FALSE