Best TWAS P=6.7e-08 · Best GWAS P=1.77e-08 conditioned to 9.32e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RERE | 0.20 | 0.23 | lasso | 2 | 0.24 | 1.7e-19 | -5.1 | -5.4 | 6.7e-08 | -0.06 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | RP5-1115A15.1 | 0.10 | 0.07 | lasso | 2 | 0.03 | 7.0e-03 | -5.1 | -5.1 | 3.1e-07 | -0.07 | 0.01 | 0.98 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Male) | RP5-1115A15.1 | 0.18 | 0.07 | lasso | 3 | 0.06 | 1.7e-02 | 3.9 | -5.3 | 8.9e-08 | -0.05 | 0.02 | 0.59 | FALSE |
| 4 | GTEx | Cells Transformed fibroblasts | RERE | 0.12 | 0.08 | lasso | 4 | 0.05 | 6.0e-05 | -5.2 | -5.2 | 2.5e-07 | -0.07 | 0.01 | 0.98 | FALSE |
| 5 | METSIM | Adipose | RERE | 0.08 | 0.12 | lasso | 17 | 0.13 | 1.8e-19 | -5.1 | -5.1 | 2.9e-07 | -0.02 | 0.01 | 0.98 | FALSE |