[Hub]/) : Traits : Neuroticism (Nagel 2018) :

chr1:7,715,776-9,571,422

Best TWAS P=6.7e-08 · Best GWAS P=1.77e-08 conditioned to 9.32e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RERE 0.20 0.23 lasso 2 0.24 1.7e-19 -5.1 -5.4 6.7e-08 -0.06 0.01 0.99 TRUE
2 GTEx Breast Mammary Tissue RP5-1115A15.1 0.10 0.07 lasso 2 0.03 7.0e-03 -5.1 -5.1 3.1e-07 -0.07 0.01 0.98 FALSE
3 GTEx Breast Mammary Tissue (Male) RP5-1115A15.1 0.18 0.07 lasso 3 0.06 1.7e-02 3.9 -5.3 8.9e-08 -0.05 0.02 0.59 FALSE
4 GTEx Cells Transformed fibroblasts RERE 0.12 0.08 lasso 4 0.05 6.0e-05 -5.2 -5.2 2.5e-07 -0.07 0.01 0.98 FALSE
5 METSIM Adipose RERE 0.08 0.12 lasso 17 0.13 1.8e-19 -5.1 -5.1 2.9e-07 -0.02 0.01 0.98 FALSE