Best TWAS P=5.4e-10 · Best GWAS P=4.46e-11 conditioned to 0.00187
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PLCL2 | 0.10 | 0.06 | lasso | 5 | 0.09 | 4.5e-07 | 6.0 | 5.8 | 6.6e-09 | 0.64 | 0.30 | 0.70 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | PLCL2 | 0.06 | 0.00 | enet | 1 | 0.00 | 5.0e-01 | 5.5 | 5.5 | 4.8e-08 | 0.82 | 0.04 | 0.77 | FALSE |
| 3 | METSIM | Adipose | PLCL2 | 0.08 | 0.03 | lasso | 6 | 0.04 | 2.3e-06 | 6.4 | 6.2 | 5.4e-10 | 0.71 | 0.03 | 0.97 | TRUE |
| 4 | YFS | Blood | PLCL2 | 0.10 | 0.10 | lasso | 7 | 0.11 | 3.7e-34 | 5.8 | 5.2 | 2.1e-07 | 0.64 | 0.20 | 0.80 | FALSE |