[Hub]/) : Traits : Neuroticism (Nagel 2018) :

chr2:147,993,969-149,475,737

Best TWAS P=8.54e-14 · Best GWAS P=3.76e-14 conditioned to 0.00663

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue (Female) ORC4 0.12 0.00 lasso 4 0.00 0.23200 7.2 -7.2 7.1e-13 -0.89 0.03 0.37 FALSE
2 The Cancer Genome Atlas Bladder Urothelial Carcinoma ORC4L 0.07 0.04 blup 37 0.03 0.00061 -5.6 7.0 3.2e-12 0.65 0.05 0.32 FALSE
3 The Cancer Genome Atlas Brain Lower Grade Glioma ORC4L 0.06 0.01 blup 37 0.03 0.00016 6.9 7.5 8.5e-14 0.79 0.01 0.97 TRUE