[Hub]/) : Traits : Neuroticism (Nagel 2018) : ← →

chr9:95,502,571-96,913,764

Best TWAS P=1.18e-10 · Best GWAS P=2.39e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	RP11-165J3.6	0.22	0.13	enet	18	0.16	2.5e-13	6.1	5.2	2.5e-07	0.92	0.01	0.99	FALSE
2	GTEx	Adipose Visceral Omentum	RP11-165J3.6	0.26	0.13	lasso	6	0.13	4.2e-07	4.8	5.6	1.6e-08	0.69	0.25	0.74	FALSE
3	GTEx	Artery Aorta	RP11-165J3.6	0.23	0.22	enet	10	0.22	2.3e-12	6.1	6.1	9.7e-10	0.96	0.02	0.98	FALSE
4	GTEx	Artery Tibial	RP11-165J3.6	0.22	0.20	lasso	2	0.19	4.9e-15	6.1	6.1	9.3e-10	0.98	0.01	0.99	FALSE
5	GTEx	Brain Caudate basal ganglia	RP11-165J3.6	0.47	0.33	lasso	7	0.31	1.0e-09	6.1	5.6	2.3e-08	0.96	0.01	0.99	FALSE
6	GTEx	Brain Cerebellum	RP11-165J3.6	0.44	0.31	lasso	7	0.28	5.0e-09	6.1	5.8	6.3e-09	0.98	0.01	0.99	FALSE
7	GTEx	Brain Frontal Cortex BA9	RP11-165J3.6	0.41	0.14	lasso	6	0.20	6.1e-06	6.1	5.9	4.1e-09	0.97	0.01	0.99	FALSE
8	GTEx	Brain Nucleus accumbens basal ganglia	RP11-165J3.6	0.31	0.11	lasso	6	0.16	5.4e-05	6.1	5.3	1.0e-07	0.85	0.02	0.92	FALSE
9	GTEx	Breast Mammary Tissue	RP11-165J3.6	0.28	0.11	enet	24	0.13	2.7e-07	6.0	5.7	9.4e-09	0.87	0.01	0.99	FALSE
10	GTEx	Breast Mammary Tissue (Female)	RP11-165J3.6	0.21	0.02	lasso	3	0.00	2.3e-01	6.0	6.2	6.2e-10	0.95	0.02	0.73	FALSE
11	GTEx	Colon Sigmoid	RP11-165J3.6	0.31	0.12	enet	17	0.16	1.8e-06	6.3	5.4	7.2e-08	0.88	0.01	0.99	FALSE
12	GTEx	Colon Transverse	RP11-165J3.6	0.37	0.20	lasso	4	0.18	3.6e-09	6.1	5.9	3.3e-09	0.96	0.01	0.99	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	RP11-165J3.6	0.34	0.26	lasso	8	0.27	3.0e-10	6.1	6.3	3.9e-10	0.98	0.01	0.99	FALSE
14	GTEx	Heart Atrial Appendage	RP11-165J3.6	0.38	0.21	lasso	7	0.25	8.7e-12	6.1	6.4	1.6e-10	0.92	0.01	0.99	FALSE
15	GTEx	Heart Left Ventricle	RP11-165J3.6	0.13	0.06	lasso	5	0.05	1.9e-03	6.1	5.5	3.7e-08	0.92	0.02	0.96	FALSE
16	GTEx	Lung	RP11-165J3.6	0.25	0.16	lasso	7	0.17	4.1e-13	6.1	6.4	1.2e-10	0.96	0.01	0.99	TRUE
17	GTEx	Pituitary	RP11-165J3.6	0.49	0.22	lasso	8	0.29	6.9e-08	6.0	6.0	1.5e-09	0.92	0.01	0.98	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	RP11-165J3.6	0.27	0.14	lasso	7	0.19	1.4e-10	6.2	6.1	1.1e-09	0.94	0.01	0.99	FALSE
19	GTEx	Skin Sun Exposed Lower leg	RP11-165J3.6	0.32	0.27	lasso	5	0.35	6.8e-30	6.0	6.2	4.3e-10	0.94	0.01	0.99	FALSE
20	GTEx	Thyroid	RP11-165J3.6	0.35	0.27	lasso	3	0.29	1.2e-22	6.1	6.3	2.2e-10	0.96	0.01	0.99	FALSE
21	YFS	Blood	FAM120AOS	0.03	0.01	bslmm	488	0.02	5.3e-06	6.0	-5.2	2.4e-07	-0.72	0.01	0.98	FALSE