TWAS hub - FAM120AOS

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Heart Atrial Appendage	0.1040	0.0490	9.1e-03	0.042	NA	0.031	NA	0.043	5.8e-03	NA	0.01600	NA	5.1e-03
2	GTEx	Skin Sun Exposed Lower leg	0.0910	0.0370	6.6e-03	0.005	NA	0.010	NA	0.003	1.2e-01	NA	0.04400	NA	1.8e-01
3	YFS	Blood	0.0325	0.0126	4.4e-05	0.014	0.013	0.009	0.016	0.013	1.6e-05	2.4e-05	0.00032	5.3e-06	3.6e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Frequency of depressed mood in last 2 weeks	14.4	20.2	27.5	-5.1	-2.7	-5.2
Depression (Nagel 2018)	13.7	20.6	30.7	-5.2	-2.1	-5.5
Loneliness, isolation	12.1	16.7	31.5	-5.6	-1.6	-4.0
Comparative body size at age 10	11.4	31.5	53.3	5.4	3.5	7.3
Major Depression (MDD)	9.5	11.5	19.9	-4.5	-2.0	-3.3
Tense / ‘highly strung’	9.0	14.8	28.6	-3.2	-2.4	-5.3
Neuroticism score	8.5	17.7	30.2	-4.5	-1.6	-5.5
Number of operations (self-reported)	8.3	12.3	14.4	-3.8	-3.0	-3.7
Frequency of unenthusiasm / disinterest in last 2 weeks	8.1	10.8	18.4	-3.7	-0.4	-4.3
Neuroticism (Nagel 2018)	8.0	18.9	26.6	-4.7	-2.7	-5.2
Depressed Affect (Nagel 2018)	7.6	16.0	25.6	-5.1	-1.9	-4.3
Neuroticism	7.5	18.1	25.4	-5.0	-2.0	-5.0
Overall health rating	6.9	14.9	26.0	-5.1	-0.8	-4.3
Worry (Nagel 2018)	6.8	14.3	26.1	-3.0	-2.8	-5.1
Mood swings	6.5	11.8	18.3	-4.3	-0.5	-4.1
Hearing difficulty/problems: Yes	6.3	9.6	19.2	-4.4	-2.5	-1.8
Frequency of tenseness / restlessness in last 2 weeks	6.3	9.9	23.1	-2.3	-1.1	-4.8
Frequency of tiredness / lethargy in last 2 weeks	6.3	10.2	18.1	-3.1	-1.7	-4.3
Miserableness	5.8	10.0	19.2	-2.7	-1.8	-4.4
Pain type(s) experienced in last month: Hip pain	5.6	7.1	11.4	-3.4	-0.0	-3.1
Pain experienced in last month	5.5	9.1	16.9	3.2	0.6	4.1
Verbal and Numeric Reasoning (VNR)	5.3	12.8	27.3	5.2	0.7	3.3
Qualifications: None of the above	5.3	11.3	22.3	-4.7	-0.5	-3.4
Medication: Paracetamol	5.3	8.8	15.2	-3.3	0.7	-3.9
Medication: Co-codamol	5.1	5.8	11.2	-3.3	-1.2	-2.2
Ever unenthusiastic/disinterested for a whole week	5.1	6.2	8.7	-2.6	-1.8	-2.9
Long-standing illness, disability or infirmity	5.1	7.9	12.6	-3.5	-1.4	-3.0
Ever depressed for a whole week	5.1	6.3	9.4	-2.1	-3.1	-2.3
Townsend deprivation index at recruitment	5.0	7.1	10.9	-3.1	-0.7	-3.3
Had other major operations	5.0	6.1	12.4	-2.2	-1.1	-3.5
Unable to work because of sickness or disability	4.8	6.3	10.4	-3.2	-0.2	-2.9
Fed-up feelings	4.5	8.2	12.7	-3.6	0.3	-3.4
Stomach or abdominal pain in last month	4.5	5.6	15.8	-0.3	1.0	-4.0
Qualifications: A levels/AS levels or equivalent	4.5	10.0	19.5	4.4	-0.6	3.2
Guilty feelings	4.5	6.8	12.5	-3.5	0.1	-2.8
Schizophrenia (2018)	4.4	9.1	14.5	-3.4	-1.1	-3.8
Other serious medical condition/disability diagnosed by doctor	4.4	5.7	9.7	-3.1	-2.3	-1.5
Pain all over the body in last month	4.4	4.7	8.7	-2.3	0.0	-3.0
Medication for pain relief, constipation, heartburn	4.4	7.6	12.1	2.6	1.9	3.5
Worrier / anxious feelings	4.3	8.1	15.1	-2.2	-2.1	-3.9
Noisy workplace	4.3	5.3	11.6	-3.4	1.5	-1.5
Financial difficulties in last 2 years	4.2	5.6	11.8	-3.4	0.5	-2.2
Medication: Ibuprofen (e.g. Nurofen)	4.2	5.3	10.4	-2.2	-1.0	-3.2
Illness, injury, bereavement, stress in last 2 years	4.2	5.1	9.5	2.1	1.2	3.1
Sensitivity / hurt feelings	4.1	7.1	10.6	-1.4	-3.3	-3.0
Falls in the last year	3.9	5.3	10.6	-2.3	-0.6	-3.2
Bipolar Disorder (2011)	3.8	3.6	8.2	-1.4	-0.9	-2.9
Schizophrenia (2014)	3.8	8.4	10.8	-3.1	-2.2	-3.3
Ever highly irritable/argumentative for 2 days	3.8	4.6	10.4	-1.8	-0.2	-3.2
Neck or shoulder pain in last month	3.8	5.4	8.1	-2.9	-1.2	-2.6
Medication: Paracetamol	3.8	5.9	8.0	-2.0	2.4	-2.8
Ever used hormone-replacement therapy (HRT)	3.7	4.7	5.6	-2.4	-1.7	-2.4
Osteoarthritis (self-reported)	3.6	4.7	8.6	-2.3	-0.4	-2.9
Neuroticism (2016)	3.5	5.1	8.9	-2.5	0.2	-3.0
Headache pain in last month	3.5	6.0	11.4	-2.3	-1.2	-3.4
Hearing aid user	3.5	3.9	9.5	-1.3	-3.1	0.7
Bipolar Disorder or Schizophrenia	3.3	8.0	14.7	-3.0	-0.5	-3.8
Number of full brothers	3.3	4.2	8.4	-2.9	0.0	-2.0
Irritability	3.3	5.6	8.7	-3.0	-0.2	-2.8
Risk taking	3.3	4.8	10.5	-3.2	-1.2	-1.5
Lupus	3.2	4.8	8.4	-2.9	1.1	-2.1
Chronic bronchitis/emphysema (father)	3.2	3.8	5.6	-1.9	-1.4	-2.4
Qualifications: College or University degree	3.2	10.2	17.9	4.2	-0.3	3.5
Qualifications: O levels/GCSEs or equivalent	3.1	4.9	10.2	3.2	-1.0	1.8
Wheeze or whistling in the chest in last year	3.1	5.5	13.6	-1.4	-1.1	-3.7
Ever had stillbirth, spontaneous miscarriage or termination	3.1	3.3	5.2	-1.8	-1.2	-2.3
Heel T-Score	2.9	22.9	62.1	-7.9	2.0	1.6
Intelligence (Savage-Jansen 2018)	2.8	8.7	21.0	4.6	-0.4	2.2
Serious illness, injury or assault to yourself	2.8	3.4	4.7	-1.8	-1.5	-2.2
Nervous feelings	2.8	5.2	7.9	-1.6	-2.8	-2.3
Hearing difficulty/problems with background noise	2.7	4.3	7.6	-2.8	-2.3	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.6	3.1	8.2	1.0	-2.9	0.3
Mouth/teeth dental problems	2.5	3.9	6.2	1.5	1.8	2.5
Father’s age at death	2.5	3.3	6.6	1.2	2.6	1.4
Mouth/teeth dental problems: Bleeding gums	2.5	3.3	4.5	-2.0	1.1	-2.1
Had major operations	2.5	2.9	6.1	-1.6	-2.5	-0.2
Illnesses of siblings: Diabetes	2.5	3.1	7.9	-2.8	-0.7	-1.0
Chronotype (morning person)	2.4	5.5	11.2	-3.3	-0.9	-2.1
Time employed in main current job	2.4	2.8	4.7	2.2	1.7	0.9
Glaucoma (self-reported)	2.4	2.8	6.4	0.4	2.5	1.4
Back pain experienced in last month	2.4	3.5	7.9	-1.7	-0.0	-2.8
Heel bone mineral density (BMD) T-score, automated (left)	2.3	5.3	11.2	-3.4	2.0	0.9
Tinnitus: Yes, but not now, but have in the past	2.3	2.4	4.7	-1.6	0.4	-2.2
Exposure to tobacco smoke at home	2.3	2.6	4.6	-0.9	-1.6	-2.1
Leg fat percentage (right)	2.3	8.4	13.8	-3.3	3.7	0.7
Leg pain on walking	2.3	2.9	4.6	-2.1	-0.9	-1.8
Number of treatments/medications taken	2.2	3.9	6.1	-1.9	-1.4	-2.5
Age at first live birth	2.2	3.9	6.4	2.5	-0.8	2.1
Qualifications: nursing, teaching	2.2	3.4	5.1	2.2	1.7	1.5
Leg fat percentage (left)	2.2	7.8	12.2	-3.2	3.5	0.9
Triglycerides	2.1	3.4	4.0	1.7	2.0	1.8
Impedance of leg (right)	2.1	10.0	19.9	-2.0	2.4	-4.5
Taking other prescription medications	2.1	3.3	3.7	-1.9	-1.9	-1.6
Impedance of leg (left)	2.1	10.2	21.0	-2.2	2.2	-4.6
Number of live births	2.1	3.0	7.6	-2.8	-0.7	-1.0
Mouth/teeth dental problems: Mouth ulcers	2.1	3.3	5.9	-0.7	-2.4	-1.9
Financial situation satisfaction	2.1	2.6	3.9	-2.0	0.5	-1.9
Ulcerative Colitis	2.0	2.9	4.6	-2.1	-1.0	-1.8
Lung FEV1/FVC ratio	2.0	10.1	22.4	-4.7	1.2	-2.5
Severe depression (siblings)	2.0	2.3	3.7	-1.9	-1.4	-1.1
Pack years adult smoking proportion	2.0	3.1	5.2	-2.3	0.4	-2.0
Heel bone mineral density (BMD) T-score, automated (right)	2.0	4.7	13.0	-3.6	0.9	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	2.0	3.0	5.2	-1.4	-1.4	-2.3
Gout (self-reported)	2.0	2.8	7.5	2.7	0.1	0.9
Eye problems/disorders: Glaucoma	2.0	2.3	5.9	0.3	2.4	1.0
Age started oral contraceptive pill	2.0	2.5	3.0	1.7	1.3	1.6
Heart disease (siblings)	2.0	2.5	6.2	-0.1	-2.5	-1.1
Age when periods started (menarche)	1.9	4.5	10.8	-1.4	-0.8	-3.3
Schizophrenia vs Biploar Disorder	1.8	2.4	3.4	-1.5	-1.9	-1.1
Medication for hormone replacement therapy	1.8	2.0	2.7	-1.3	-1.2	-1.7
Knee pain experienced in last month	1.8	2.8	4.4	-1.6	-1.2	-2.1
Number of self-reported non-cancer illnesses	1.8	3.1	5.4	-2.3	-0.2	-2.0
Hand grip strength (left)	1.7	4.4	7.9	2.1	1.0	2.8
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	2.9	-1.7	1.2	-1.3
Fluid intelligence score	1.7	3.5	8.6	2.9	0.4	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	1.7	5.3	13.9	-0.9	-1.2	-3.7
Hypothyroidism/myxoedema (self-reported)	1.7	3.3	6.9	-2.6	-1.1	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	3.9	-0.9	-1.2	-2.0
Illnesses of father: None of the above (group 1)	1.7	2.1	3.5	0.6	1.9	1.5
Fractured/broken bones in last 5 years	1.7	2.2	5.4	0.3	-2.3	-1.1
Medication: Omeprazole (e.g. Zanprol)	1.7	2.0	3.8	1.5	-1.9	0.2
HDL Cholesterol	1.6	2.7	5.6	-1.2	-2.4	-1.1
Medication: Ibuprofen	1.6	1.9	4.5	-1.0	-0.0	-2.1
Friendships satisfaction	1.6	2.0	5.6	-2.4	0.4	-0.5
Average weekly champagne plus white wine intake	1.6	2.2	3.6	1.3	-1.2	1.9
Tinnitus: Yes, now most or all of the time	1.6	1.9	2.5	-1.0	-1.5	-1.6
Cholesterol lowering medication	1.6	2.3	4.2	1.6	-0.2	2.1
Hand grip strength (right)	1.5	4.0	7.6	2.8	0.6	2.0
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	4.7	-0.7	-0.9	-2.2
Worry too long after embarrassment	1.5	2.5	4.7	-1.3	-1.1	-2.2
Medication for cholesterol	1.5	2.3	5.6	1.1	2.4	0.2
Commuting to job workplace: Cycle	1.5	1.8	4.5	0.3	2.1	0.9
Alzheimer’s Disease (in father)	1.4	1.6	2.5	-0.7	-1.3	-1.6
Angina	1.4	1.8	3.9	-0.9	-2.0	-0.9
Relative age voice broke	1.4	2.2	5.1	-0.6	-1.0	-2.3
Medication: Levothyroxine sodium	1.4	2.4	5.4	-2.3	-0.8	-1.0
Hair/balding pattern: Pattern 4	1.4	3.4	7.3	-1.2	2.7	-1.1
Health satisfaction	1.4	1.9	2.2	-1.3	-1.5	-1.2
Smoking status: Previous	1.4	2.1	3.4	1.5	-0.8	1.8
Pack years of smoking	1.4	2.1	3.8	-2.0	0.5	-1.5
Age at First Birth	1.3	1.9	3.6	1.9	0.6	1.3
Body Mass Index (BMI) (2010)	1.3	1.8	3.5	-0.1	1.9	1.4
LDL Cholesterol	1.3	2.0	4.6	1.0	2.1	0.7
Heart attack	1.3	1.7	4.9	0.1	-2.2	-0.4
Arm fat percentage (right)	1.3	5.0	9.0	-0.8	2.3	3.0
Mouth/teeth dental problems: Loose teeth	1.3	1.5	4.1	0.4	-2.0	0.5
Angina (self-reported)	1.3	1.7	3.7	-0.8	-1.9	-0.9
Alcohol drinker status: Previous	1.3	1.4	3.4	-0.6	-0.8	-1.8
BMI	1.2	6.7	12.5	-1.3	2.4	3.5
Maternal smoking around birth	1.2	1.8	2.1	1.3	1.4	1.3
Body mass index (BMI)	1.2	5.0	7.2	-2.1	1.9	2.7
Waist circumference	1.2	4.4	5.5	-1.9	2.0	2.3
Number of incorrect matches in round	1.2	1.9	3.8	-1.4	-0.3	-1.9
Past tobacco smoking	1.2	2.3	3.0	-1.7	1.1	-1.6
Happiness	1.2	1.4	3.8	-0.7	0.2	-2.0
Mouth/teeth dental problems: Dentures	1.2	2.0	4.7	0.2	-1.2	-2.2
Prospective memory result	1.2	1.5	2.2	-1.4	-1.5	0.6
Medication: Ventolin 100micrograms inhaler	1.2	1.6	3.3	1.1	1.8	0.5
Chronic bronchitis/emphysema (mother)	1.2	1.5	2.5	1.6	-0.1	1.4
Leg fat mass (right)	1.2	4.7	8.1	-2.8	2.2	1.1
Suffer from ‘nerves’	1.2	2.0	4.0	-0.7	-1.2	-2.0
Commuting to job workplace: Walk	1.2	1.2	1.8	1.1	1.3	-0.8
Ever taken oral contraceptive pill	1.2	1.3	3.0	0.8	-1.7	-0.5
Basal cell carcinoma (self-reported)	1.2	1.4	2.7	-1.2	-1.6	0.3
Leg fat mass (left)	1.2	4.5	7.8	-2.8	2.1	1.2
Relative age of first facial hair	1.1	2.3	5.4	-0.3	-1.1	-2.3
Bilateral oophorectomy (both ovaries removed)	1.1	1.2	2.8	-1.7	-0.9	0.0
Impedance of arm (right)	1.1	5.1	14.9	3.9	0.6	-0.1
Forced vital capacity (FVC), Best measure	1.1	3.9	8.7	0.5	-1.7	-2.9
Body fat percentage	1.1	4.2	5.7	-2.1	2.4	1.6
Medication: Seretide 50 evohaler	1.1	1.3	2.5	1.6	0.7	1.0
Family relationship satisfaction	1.1	1.4	2.6	-1.6	0.7	-1.0
Arm fat percentage (left)	1.1	4.3	8.8	-1.0	1.8	3.0
Commuting to job workplace: Public transport	1.1	1.3	2.0	1.4	-0.7	1.2
Blood Platelet Count	1.0	11.3	23.2	-4.8	1.1	-3.0
Smoking Status	1.0	2.3	3.6	1.7	-1.9	0.7
High blood pressure (mother)	1.0	1.4	2.8	-0.9	0.8	-1.7
Alcohol usually taken with meals	1.0	1.7	3.8	1.1	-1.9	0.4
Hair/balding pattern: Pattern 2	1.0	1.3	1.7	1.3	-1.3	-0.7
Medication: Amlodipine	1.0	1.4	1.8	-1.3	-0.9	-1.3
Medication: Blood pressure	1.0	2.0	4.0	-1.1	-2.0	0.8
Illnesses of father: High blood pressure	1.0	1.2	2.3	-1.5	0.7	-0.9
Heart attack/myocardial infarction (self-reported)	1.0	1.3	3.6	0.5	-1.9	-0.2
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	2.3	0.3	1.5	1.2
Vitamin and mineral supplements	0.9	1.2	1.9	-0.1	1.3	1.4
Average weekly fortified wine intake	0.9	1.1	1.6	0.5	1.3	1.1
Hayfever, allergic rhinitis or eczema	0.9	2.0	5.7	-0.2	0.3	-2.4
Medication: Atenolol	0.9	1.1	2.9	-0.1	-0.5	1.7
Diabetes (self-reported)	0.9	1.4	2.2	-1.2	-1.5	-0.8
Alcohol intake versus 10 years previously	0.9	1.4	2.2	-1.4	1.5	-0.3
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	6.3	0.1	-1.5	-2.5
Pulse wave Arterial Stiffness index	0.9	1.0	2.8	0.4	-1.7	-0.2
Impedance of arm (left)	0.9	4.3	12.8	3.6	-0.2	-0.3
Loud music exposure frequency	0.9	1.0	2.1	-0.8	0.4	-1.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	2.9	-0.7	-1.7	-0.2
Alcohol intake frequency.	0.9	2.1	3.6	-1.9	0.1	-1.6
Comparative height size at age 10	0.9	4.9	8.6	2.9	-0.8	2.3
Diabetes diagnosed by doctor	0.9	1.4	3.2	-1.0	-1.8	-0.2
Osteoporosis (self-reported)	0.9	1.1	1.7	-0.8	-1.3	-0.9
Average weekly beer plus cider intake	0.9	1.3	2.8	-1.7	0.2	-1.0
Height	0.8	16.3	37.8	0.2	-6.2	-3.3
Respiratory disease	0.8	1.8	3.4	-1.3	0.4	-1.8
Diabetes (father)	0.8	1.0	1.4	-1.1	1.2	-0.6
Trunk fat percentage	0.8	3.1	4.6	-1.7	2.1	1.3
Allergy	0.8	1.9	4.1	-0.0	-1.3	2.0
Medication: Ramipril	0.8	1.0	2.6	0.5	-1.6	0.4
Hair/balding pattern: Pattern 3	0.8	1.2	2.5	1.6	-0.2	1.0
Arm fat mass (right)	0.8	3.1	4.5	-1.7	1.4	2.1
Breastfed as a baby	0.8	1.0	2.6	-0.7	-1.6	0.2
Birth weight of first child	0.8	1.4	3.4	1.8	-0.7	0.7
Shortness of breath walking on level ground	0.8	0.9	2.3	-1.5	0.2	-0.7
Eye problems/disorders: None of the above	0.8	0.9	2.0	1.4	0.5	0.6
Migraine (self-reported)	0.8	1.0	2.1	-0.8	1.4	-0.3
Medication: Omeprazole	0.8	1.0	2.7	0.4	-1.6	-0.2
Arm predicted mass (right)	0.8	4.2	9.6	-3.1	-1.7	-0.3
Age at last live birth	0.8	1.2	1.7	1.3	-0.6	1.2
Commuting to job workplace: Car/motor vehicle	0.8	0.9	2.7	-0.2	-0.2	1.6
Medication: Aspirin	0.8	1.1	1.4	-1.2	-1.1	-0.8
Hypertension (Self-reported)	0.8	2.3	3.3	-1.6	-1.0	1.8
Handedness (chirality/laterality): Left-handed	0.8	1.0	1.4	-1.1	0.7	1.2
Eye problems/disorders: Cataract	0.8	0.9	1.4	-1.2	-1.1	-0.2
Arm fat mass (left)	0.8	3.3	5.4	-1.8	1.1	2.3
Alcohol drinker status: Never	0.8	1.0	1.7	-1.1	-1.3	0.1
Supplements: Calcium	0.8	0.8	1.2	1.1	-1.1	-0.4
Coronary Artery Disease (CAD)	0.7	0.9	0.9	-0.9	0.9	-1.0
Blood Red Count	0.7	6.8	13.0	1.2	3.6	2.4
Allergy or Eczema	0.7	1.9	5.2	-0.7	-0.2	-2.3
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.2	0.0	1.5	0.3
Multivitamins +/- minerals	0.7	0.8	2.4	0.3	-0.1	-1.5
Sitting height	0.7	4.7	5.8	-1.8	-2.2	-2.4
Forced vital capacity (FVC)	0.7	2.8	4.5	1.3	-1.5	-2.1
Asthma	0.7	1.5	3.7	-0.3	0.8	-1.9
Depression (self-reported)	0.7	0.9	1.4	-0.2	-1.0	-1.2
Blood clot in the leg (DVT)	0.7	0.9	2.1	-0.1	1.4	0.7
Medication for cholesterol, blood pressure or diabetes	0.7	1.1	1.8	1.3	-0.5	-1.2
Arm fat-free mass (right)	0.7	3.8	8.1	-2.8	-1.7	-0.6
Medication: Blood pressure	0.7	1.2	2.4	-1.5	0.1	1.1
Whole body fat mass	0.7	2.8	4.3	-2.1	1.4	1.4
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	2.3	-0.6	-1.3	-1.5
Ever had bowel cancer screening	0.7	0.9	1.8	-0.9	0.1	-1.3
Breast cancer (self-reported)	0.7	0.8	1.3	-1.1	0.0	-1.1
Supplements: Fish oil (including cod liver oil)	0.7	1.0	2.1	0.9	1.5	-0.1
Vascular/heart problems diagnosed by doctor	0.7	2.0	2.4	1.4	1.5	-1.2
Bipolar Disorder (2018)	0.6	0.9	2.0	-0.6	0.6	-1.4
Alzheimer’s Disease (in mother)	0.6	0.8	1.2	1.0	0.4	1.1
Crohns Disease (2017)	0.6	1.2	2.2	-1.5	-0.2	-1.2
Irritable Bowel Disease (IBD)	0.6	1.5	3.1	-1.8	-0.4	-1.1
Systolic Blood Pressure	0.6	3.1	8.1	0.2	-2.8	-1.1
Medication: Metformin	0.6	0.8	2.1	-1.5	-0.4	-0.4
Qualifications: CSEs or equivalent	0.6	0.8	1.7	-0.8	1.3	-0.1
High blood pressure	0.6	1.6	2.6	-1.6	-0.8	1.2
Pulse rate	0.6	1.1	2.4	-0.8	-1.6	0.3
Standing height	0.6	6.4	10.8	0.5	-3.3	-2.8
Medication: Allopurinol	0.6	0.9	1.9	1.4	-0.6	0.6
Heart disease (mother)	0.6	0.7	2.0	0.1	0.1	-1.4
Supplements: Vitamin C	0.6	0.7	1.6	-0.2	-1.3	-0.7
Asthma (self-reported)	0.6	1.2	3.0	-0.2	0.8	-1.7
Smoking status: Current	0.6	1.0	1.7	-0.1	-1.1	-1.3
Medication: Bendroflumethiazide	0.6	0.8	2.4	-1.5	-0.4	0.2
Medication: Lisinopril	0.6	0.8	1.8	-1.3	-0.8	0.2
Arm fat-free mass (left)	0.6	3.1	8.1	-2.8	-0.9	-0.5
Ever had prostate specific antigen (PSA) test	0.6	0.7	2.0	0.1	1.4	-0.2
Impedance of whole body	0.6	3.2	7.7	1.0	0.8	-2.8
Arm predicted mass (left)	0.6	3.3	8.4	-2.9	-1.1	-0.4
Ulcerative Colitis (UC)	0.5	0.9	1.9	-1.4	-0.7	-0.5
Crohns Disease (2012)	0.5	0.9	1.2	-1.1	-0.7	-0.9
HbA1C	0.5	0.5	0.9	0.9	0.7	0.5
Rheumatoid Arthritis	0.5	0.7	1.4	-1.2	-0.7	-0.5
Blood Eosinophil Count	0.5	3.9	5.8	1.7	2.4	1.7
Blood White Count	0.5	3.9	10.9	0.2	3.3	0.9
Cardiovascular Disease	0.5	1.5	2.1	-0.9	-1.2	1.5
Supplements: Zinc	0.5	0.6	1.4	1.2	-0.6	-0.1
Diabetes (mother)	0.5	0.6	1.1	-0.9	-1.0	-0.2
Current tobacco smoking	0.5	0.8	1.9	-0.1	-0.7	-1.4
Trunk fat mass	0.5	2.3	3.2	-1.8	1.4	1.4
Medication: Simvastatin	0.5	0.7	1.6	0.8	0.1	1.3
Illnesses of siblings	0.5	0.7	1.5	1.2	0.8	-0.1
Illnesses of mother	0.5	0.6	0.9	-0.5	-0.9	0.9
Length of working week for main job	0.5	0.5	1.2	0.7	1.1	0.1
Pulse wave peak to peak time	0.5	0.6	1.6	-0.1	1.3	0.2
Emphysema/chronic bronchitis	0.5	0.6	0.6	0.8	0.8	0.8
Mean time to correctly identify matches	0.5	0.9	1.9	-0.5	1.4	-0.8
Leg fat-free mass (right)	0.5	2.5	4.1	0.3	-2.0	1.8
Average weekly red wine intake	0.5	0.7	1.2	0.5	-1.1	-0.8
Leg predicted mass (right)	0.5	2.6	4.7	0.2	-2.2	1.7
Medication: Atorvastatin	0.5	0.6	1.7	0.3	-0.1	1.3
Ever smoked	0.5	0.8	2.0	-0.0	-1.4	-0.6
Myopia	0.5	0.7	1.6	1.3	0.5	0.3
Type 2 Diabetes (T2D) (2018)	0.4	0.7	1.0	-0.6	-0.9	1.0
Ever had hysterectomy (womb removed)	0.4	0.5	0.9	-0.9	-0.6	0.5
Trunk fat-free mass	0.4	2.4	4.7	-1.5	-2.2	-0.2
Hip circumference	0.4	1.9	4.5	-0.6	0.9	2.1
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.0	0.4	-1.0	-0.3
Trunk predicted mass	0.4	2.3	4.7	-1.5	-2.2	-0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.1	-0.6	-0.3	1.1
Illnesses of father: Heart disease	0.4	0.5	0.8	0.8	-0.3	0.9
Medication: Aspirin	0.4	0.5	0.8	-0.9	-0.4	-0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.8	1.1	0.7	1.0	-0.9
Wears glasses or contact lenses	0.4	0.5	0.7	0.0	0.8	-0.8
Ovarian Cancer	0.3	0.4	1.2	-1.1	-0.3	-0.0
Fasting Glucose	0.3	0.4	0.8	0.1	0.5	0.9
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.6	0.3	0.4	0.8
Waist Hip Ratio (WHR)	0.3	1.3	2.0	-1.4	1.4	-0.2
Hypothyroidism (self reported)	0.3	0.6	1.0	-0.9	-1.0	0.4
Average weekly spirits intake	0.3	0.4	1.0	-0.1	-0.5	1.0
Leg fat-free mass (left)	0.3	1.8	2.9	-0.1	-1.6	1.7
Supplements: Glucosamine	0.3	0.4	0.5	0.7	-0.4	-0.7
Leg predicted mass (left)	0.3	1.7	2.6	-0.2	-1.5	1.6
Had menopause	0.3	0.3	0.9	0.0	0.9	0.3
Weight	0.3	1.5	2.9	-1.7	0.3	1.2
Medication: Cholesterol lowering	0.3	0.4	1.2	-1.1	-0.2	0.4
Medication: Lansoprazole	0.3	0.3	0.5	0.7	0.3	0.7
Birth weight	0.3	0.6	1.5	1.2	0.2	0.4
High blood pressure (siblings)	0.3	0.4	1.0	-1.0	-0.1	-0.4
Exposure to tobacco smoke outside home	0.3	0.4	1.0	-0.4	-0.4	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.5	0.5	0.5	0.7
Number of full sisters	0.3	0.4	0.6	-0.8	-0.6	-0.3
Chest pain or discomfort	0.3	0.4	0.6	-0.6	-0.3	-0.8
Whole body fat-free mass	0.3	1.9	4.1	-1.2	-2.0	0.5
Whole body water mass	0.3	2.0	4.2	-1.1	-2.1	0.6
High cholesterol (Self-reported)	0.3	0.5	0.9	0.8	-0.3	0.9
Basal metabolic rate	0.3	1.5	2.0	-1.4	-1.4	0.6
Diastolic blood pressure, automated reading	0.3	1.0	2.8	-1.7	0.0	-0.3
Reaction Time	0.2	0.4	0.8	-0.1	0.6	-0.9
Breast Cancer	0.2	0.4	1.1	0.5	0.0	1.0
Lung FVC	0.2	1.2	3.1	-0.2	-0.7	-1.8
Tanning	0.2	2.1	3.1	-1.0	-1.8	-1.5
Systolic blood pressure, automated reading	0.2	0.7	2.0	-0.3	-1.4	0.1
Peak expiratory flow (PEF)	0.2	0.5	1.0	0.3	-0.7	-1.0
Number of children fathered	0.2	0.3	0.7	-0.3	-0.0	0.9
Pulse rate, automated reading	0.2	0.6	1.8	0.2	-1.3	0.1
Mineral and other dietary supplements	0.2	0.3	0.7	-0.9	-0.1	0.4
Medication: Gliclazide	0.2	0.3	0.8	0.1	-0.9	-0.1
Mother’s age at death	0.2	0.3	0.4	-0.6	-0.4	-0.5
Mean Putamen Volume	0.1	0.1	0.2	-0.4	-0.4	-0.0
Primary Biliary Cirrhosis	0.1	0.1	0.2	-0.2	-0.3	0.5
Pulse wave reflection index	0.1	0.1	0.2	-0.1	-0.4	0.4
Alzheimer’s Disease (including proxy)	0.0	0.0	0.1	0.1	-0.2	0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	1.1	3.1	1.8	-0.5	-0.2
Lung cancer (father)	0.0	0.1	0.1	-0.1	-0.2	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.0	0.1	0.2	-0.1

Hub : Genes

FAM120AOS

Models

Trait associations