Best TWAS P=3.79e-09 · Best GWAS P=1.9e-10 conditioned to 0.000217
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | RCN1 | 0.07 | 0.00 | blup | 176 | 0.01 | 4.2e-02 | -0.28 | -5.2 | 2.2e-07 | -0.43 | 0.03 | 0.18 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PAX6 | 0.11 | 0.06 | enet | 3 | 0.05 | 4.2e-06 | 5.51 | 5.2 | 2.2e-07 | 0.40 | 0.30 | 0.57 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | PAX6 | 0.11 | 0.11 | lasso | 3 | 0.09 | 2.2e-09 | 5.51 | 5.9 | 3.8e-09 | 0.56 | 0.34 | 0.66 | TRUE |