Best TWAS P=2.61e-08 · Best GWAS P=3.1e-07 conditioned to 0.00343
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | TOP3A | 0.08 | 0.00 | enet | 15 | 0.00 | 0.6460 | 3.8 | -5.3 | 1.5e-07 | 0.53 | 0.05 | 0.14 | FALSE |
| 2 | METSIM | Adipose | SREBF1 | 0.03 | 0.00 | bslmm | 420 | 0.02 | 0.0020 | 3.8 | 5.6 | 2.6e-08 | -0.45 | 0.15 | 0.46 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | FLII | 0.03 | 0.01 | lasso | 4 | 0.00 | 0.0839 | -4.8 | 5.1 | 2.8e-07 | -0.81 | 0.00 | 0.46 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | FLII | 0.05 | 0.04 | blup | 47 | 0.03 | 0.0017 | -4.5 | 5.1 | 3.1e-07 | -0.71 | 0.01 | 0.53 | FALSE |