Hub : Genes

SREBF1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adrenal Gland 0.1671 0.0994 7.1e-03 0.111 NA 0.068 NA 0.092 8.5e-05 NA 1.9e-03 NA 3.5e-04
2 GTEx Artery Aorta 0.1090 0.0490 7.6e-05 0.129 NA 0.066 NA 0.103 1.4e-07 NA 1.6e-04 NA 2.6e-06
3 GTEx Cells Transformed fibroblasts 0.0890 0.0500 5.0e-03 0.010 NA 0.011 NA 0.013 5.9e-02 NA 4.9e-02 NA 3.2e-02
4 GTEx Thyroid 0.0730 0.0350 1.2e-03 0.009 NA 0.045 NA 0.028 5.7e-02 NA 2.2e-04 NA 3.3e-03
5 GTEx Whole Blood 0.0440 0.0180 1.0e-04 0.059 NA 0.046 NA 0.049 3.5e-06 NA 4.3e-05 NA 2.4e-05
6 METSIM Adipose 0.0333 0.0174 1.6e-03 0.003 0.015 0.002 0.015 0.002 9.4e-02 2.2e-03 1.7e-01 2.0e-03 1.5e-01
7 YFS Blood 0.0742 0.0219 0.0e+00 0.113 0.103 0.108 0.108 0.108 6.5e-35 8.1e-32 2.7e-33 2.8e-33 2.2e-33
8 TCGA Stomach Adenocarcinoma 0.0430 0.0360 4.1e-03 0.025 0.023 0.008 NA 0.018 5.9e-03 7.8e-03 7.4e-02 NA 1.8e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.2 0.3 0.9 0.1 0.8 -0.6 1.0 -0.1 0.3 0.0 0.3
Bipolar Disorder or Schizophrenia 4.9 11.9 16.6 4.1 3.7 2.0 4.0 -4.0 1.4 -3.6 3.7
Depressed Affect (Nagel 2018) 1.0 2.1 16.5 0.2 -0.5 -0.0 -0.3 -0.1 4.1 -0.2 -0.4
Depression (Nagel 2018) 1.3 1.9 7.3 1.5 1.3 0.4 0.1 -1.3 2.7 -1.2 0.9
Intelligence (Savage-Jansen 2018) 4.5 13.7 21.2 -4.5 -3.0 -3.9 -2.6 4.3 -1.0 4.2 -4.6
Neuroticism (Nagel 2018) 2.1 5.0 31.0 0.9 0.2 1.9 0.7 -1.4 5.6 -1.3 0.7
Schizophrenia (2018) 8.5 17.7 26.5 5.1 4.2 3.0 4.4 -5.0 1.5 -4.7 4.5
Schizophrenia vs Biploar Disorder 5.4 7.2 10.6 3.0 2.9 2.3 1.8 -3.1 1.1 -3.2 3.3
Worry (Nagel 2018) 2.1 4.3 16.0 1.4 0.8 2.7 1.3 -1.7 4.0 -1.6 1.2
Alzheimer’s Disease (in mother) 7.8 9.1 15.7 -3.1 -2.8 -4.0 -2.8 3.0 -1.5 2.9 -3.5
Alzheimer’s Disease (in father) 1.2 1.3 2.6 -0.8 -1.4 -1.4 -1.6 1.0 -0.0 1.0 -1.0
Alzheimer’s Disease (including proxy) 6.9 10.0 17.4 -2.7 -3.2 -4.2 -3.2 3.2 -1.0 3.3 -3.6
Crohns Disease (2017) 0.2 0.5 1.1 -1.0 -0.7 0.1 -0.1 0.8 1.1 0.8 -0.7
Irritable Bowel Disease (IBD) 0.4 1.0 5.5 -0.7 -0.5 1.1 0.1 0.2 2.4 0.1 -0.2
Ulcerative Colitis (UC) 0.6 1.1 5.4 -0.2 -0.0 1.5 0.5 -0.4 2.3 -0.7 0.4
Major Depression (MDD) 0.8 1.0 4.1 -2.0 -0.3 -0.7 -0.5 1.1 0.0 0.8 -1.1
Reaction Time 5.7 10.9 23.1 3.4 1.4 2.4 1.2 -4.4 1.8 -4.8 4.5
Verbal and Numeric Reasoning (VNR) 5.8 13.8 24.5 -4.6 -2.8 -3.7 -2.6 4.3 -0.7 4.2 -5.0
Breast Cancer 4.0 9.7 14.1 -2.9 -2.8 -3.4 -2.5 3.8 -3.0 3.3 -3.0
Ovarian Cancer 1.5 2.0 4.5 2.0 0.7 1.1 -0.6 -2.1 -0.6 -1.9 1.2
Prostate Cancer 5.0 7.0 10.2 2.4 2.2 3.0 2.1 -3.0 1.6 -3.2 3.1
Age at First Birth 0.5 0.7 1.7 -0.9 -0.4 -0.5 0.3 1.0 -0.5 1.3 -1.1
Bipolar Disorder (2011) 3.3 3.2 6.3 1.5 0.4 1.4 1.6 -1.8 2.3 -2.0 2.5
Body Mass Index (BMI) (2010) 3.6 4.9 6.0 -2.1 -2.5 -2.2 -2.4 2.3 -1.0 2.5 -2.5
Coronary Artery Disease (CAD) 12.5 14.9 21.3 4.0 3.8 3.3 3.1 -4.2 3.4 -4.3 4.6
Crohns Disease (2012) 0.2 0.3 1.2 0.0 -0.4 0.0 -0.9 -0.1 1.1 -0.2 0.4
Mean Putamen Volume 0.2 0.3 1.3 -0.2 -0.5 0.4 -0.7 -0.0 1.1 -0.0 0.0
Fasting Glucose 0.9 1.1 2.1 -1.2 -1.1 -0.9 0.2 1.3 0.3 1.5 -1.1
HbA1C 5.8 6.4 12.4 3.1 1.4 2.2 2.0 -2.9 0.6 -3.1 3.5
HDL Cholesterol 1.3 2.1 3.9 -1.6 -1.9 -1.3 -0.9 1.5 -0.4 1.3 -2.0
LDL Cholesterol 0.7 1.0 5.7 -0.1 0.3 0.5 1.5 -0.1 2.4 -0.3 0.0
Lupus 0.9 1.4 3.7 1.0 1.9 1.8 0.4 -1.3 -0.0 -1.1 0.6
Neuroticism (2016) 0.9 1.3 4.4 -1.1 -0.9 -0.7 -1.0 0.9 2.1 1.1 -0.7
Primary Biliary Cirrhosis 0.1 0.2 0.8 0.1 0.2 -0.9 -0.4 0.2 -0.5 0.3 -0.3
Rheumatoid Arthritis 0.6 0.8 4.1 -0.1 0.3 2.0 0.3 -0.3 1.3 -0.3 0.6
Schizophrenia (2014) 8.6 19.1 28.0 4.9 3.9 3.7 4.2 -5.3 2.2 -5.0 4.9
Triglycerides 3.5 5.8 10.5 2.4 2.2 2.1 2.6 -2.7 1.2 -2.5 3.2
Type 2 Diabetes (T2D) (2012) 1.9 2.2 6.1 0.9 0.2 1.6 1.8 -1.4 0.0 -1.6 2.5
Ulcerative Colitis 0.5 0.7 2.8 -0.7 -0.9 0.5 -0.6 0.3 1.7 0.4 -0.6
Blood Eosinophil Count 2.9 22.4 34.3 4.2 2.6 5.9 2.8 -5.2 5.1 -5.2 5.7
Blood Platelet Count 0.2 2.8 5.4 1.4 1.3 0.1 1.8 -1.8 2.0 -1.7 2.3
Blood Red Count 2.0 19.0 29.7 5.0 3.5 5.4 1.2 -5.2 1.2 -5.0 5.5
Blood White Count 7.0 52.1 95.5 7.4 5.9 7.2 5.8 -8.2 3.7 -8.2 9.8
Heel T-Score 1.3 10.1 18.7 -3.2 -2.9 -2.8 -1.8 3.4 -2.4 3.9 -4.3
BMI 1.1 6.6 10.8 -3.3 -2.8 -1.8 -1.7 2.9 -1.5 3.0 -3.0
Height 1.0 19.2 47.6 6.9 4.3 4.0 1.8 -5.0 -0.7 -4.6 4.8
Waist Hip Ratio (WHR) 14.9 67.1 89.1 8.9 7.9 7.6 7.6 -8.7 6.6 -8.6 9.4
Systolic Blood Pressure 3.5 17.5 25.6 3.3 3.0 5.1 1.4 -4.8 4.6 -5.0 4.7
Smoking Status 0.5 1.3 2.1 -1.1 -0.6 -1.5 -1.0 1.3 -0.5 1.3 -1.3
Allergy or Eczema 5.3 13.9 30.2 3.7 2.7 3.4 1.5 -4.7 1.3 -4.7 5.5
Cardiovascular Disease 2.1 6.9 18.8 1.1 1.7 3.0 2.6 -2.2 4.3 -2.4 2.3
Hypothyroidism (self reported) 1.4 3.1 4.8 1.0 2.2 1.7 1.7 -1.6 1.8 -1.7 2.2
Respiratory disease 0.3 0.8 1.2 0.7 0.8 1.1 0.3 -0.8 1.1 -1.0 1.0
Type 2 Diabetes (T2D) (2018) 4.6 8.6 11.0 2.4 3.0 3.3 2.8 -3.2 2.2 -3.3 3.2
Lung FEV1/FVC ratio 4.4 22.5 33.1 4.9 4.9 4.2 4.7 -5.2 2.9 -4.9 5.8
Lung FVC 3.7 18.7 30.2 -4.3 -3.3 -5.2 -2.7 5.5 -1.9 5.3 -5.0
Neuroticism 1.7 4.2 21.6 1.1 0.7 1.8 0.8 -1.6 4.7 -1.5 1.3
Chronotype (morning person) 0.6 1.4 8.3 -0.5 0.5 0.9 2.9 0.5 -0.6 0.7 -0.9
Hair Pigment 0.3 7.4 17.6 -3.2 -1.5 -4.2 -0.2 3.3 -1.3 3.3 -2.5
Tanning 0.1 1.6 6.1 -0.1 -2.2 -0.3 -2.5 0.6 -0.6 0.6 -0.8
Hand grip strength (left) 0.1 0.4 1.3 0.6 1.1 -0.5 -0.6 0.5 0.5 0.5 0.1
Number of treatments/medications taken 1.8 3.2 5.2 0.9 -0.3 2.0 1.1 -2.0 2.3 -2.3 2.2
Average weekly spirits intake 3.6 4.5 7.0 1.9 2.1 2.0 1.5 -2.4 2.1 -2.6 2.2
Sensitivity / hurt feelings 5.9 10.1 20.9 2.6 2.0 3.5 1.1 -3.4 4.6 -3.5 3.5
Frequency of depressed mood in last 2 weeks 1.4 2.0 3.2 1.6 1.1 0.8 0.3 -1.8 1.8 -1.7 1.4
Hearing difficulty/problems: Yes 1.0 1.5 3.2 1.8 1.6 0.9 0.7 -1.4 0.5 -1.1 1.3
Relative age of first facial hair 0.2 0.5 2.1 -0.3 -0.5 -0.8 -0.3 0.4 -1.5 0.5 -0.5
Other serious medical condition/disability diagnosed by doctor 0.2 0.3 0.8 -0.8 -0.9 -0.1 -0.2 0.5 -0.7 0.4 0.1
Ever used hormone-replacement therapy (HRT) 3.5 4.5 10.2 -2.4 -3.2 -2.0 -2.7 1.7 -0.3 1.6 -1.8
Ever had hysterectomy (womb removed) 0.5 0.5 2.5 0.5 -0.8 -0.6 -1.6 -0.3 -0.2 -0.1 0.5
Systolic blood pressure, automated reading 2.3 6.6 10.7 2.3 1.8 3.3 0.7 -3.3 1.9 -3.2 2.9
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 1.7 0.6 0.4 0.5 0.2 -0.9 0.5 -1.1 1.3
Angina 2.5 3.2 6.5 2.4 0.6 0.5 0.9 -2.3 1.0 -2.4 2.6
Medication for hormone replacement therapy 0.7 0.8 2.1 -1.5 -1.2 -0.6 -1.1 0.8 -0.1 0.4 -0.7
Vitamin and mineral supplements 1.6 2.1 4.6 2.1 0.5 1.0 -0.1 -1.9 0.0 -2.0 1.8
Supplements: Zinc 0.8 0.9 2.7 -0.8 -0.9 -0.1 0.2 1.0 -1.6 1.1 -0.8
Medication: Co-codamol 0.6 0.7 1.5 0.1 -0.6 1.2 0.1 -0.9 0.9 -1.1 0.7
Medication: Metformin 1.7 2.3 3.3 1.2 1.4 1.8 1.0 -1.6 1.7 -1.6 1.7
Diabetes (father) 0.1 0.2 0.5 0.1 0.0 0.2 0.1 -0.4 0.5 -0.7 0.6
Diabetes (mother) 1.9 2.5 4.9 2.1 1.8 0.5 1.2 -1.8 0.2 -1.6 2.2
Severe depression (siblings) 0.3 0.3 0.8 -0.3 -0.2 -0.5 0.3 0.7 0.6 0.7 -0.9
Pack years adult smoking proportion 1.6 2.4 5.8 0.8 0.5 1.0 0.6 -2.0 1.3 -2.4 2.3
Impedance of leg (right) 5.2 25.1 35.8 4.9 4.5 5.2 4.8 -5.6 3.2 -6.0 5.5
Leg fat-free mass (left) 1.3 7.0 12.2 -1.7 -1.0 -2.4 -2.5 2.9 -3.4 3.5 -2.9
Trunk fat percentage 0.1 0.4 1.9 -0.9 -0.4 0.3 -0.1 0.2 -1.4 0.3 -0.6
Hand grip strength (right) 0.1 0.2 0.9 0.3 -0.1 -0.3 -1.0 0.5 0.7 0.4 -0.0
Townsend deprivation index at recruitment 2.5 3.6 6.1 -2.4 -1.7 -1.5 -1.0 2.5 -0.7 2.4 -2.1
Current tobacco smoking 0.7 1.2 2.2 1.4 0.8 0.8 0.8 -1.5 -0.4 -1.1 1.4
Average weekly fortified wine intake 0.8 0.9 4.1 -0.6 -0.3 -1.5 -2.0 0.3 -0.0 0.4 -0.6
Maternal smoking around birth 3.6 5.3 8.9 -2.6 -3.0 -1.7 -1.0 2.8 -0.3 2.7 -2.7
Fed-up feelings 2.3 4.2 13.8 1.6 0.5 1.4 0.3 -2.2 3.7 -2.3 2.2
Frequency of unenthusiasm / disinterest in last 2 weeks 4.8 6.4 13.8 2.2 2.3 2.3 2.5 -2.5 3.7 -2.4 2.0
Relative age voice broke 1.2 1.8 3.3 -1.5 -1.0 -1.1 -1.5 1.3 -1.8 1.2 -1.2
Taking other prescription medications 1.2 1.8 6.1 0.3 -0.3 2.5 1.2 -1.1 1.6 -1.1 1.2
Age when periods started (menarche) 1.7 4.1 9.6 1.2 0.5 2.0 1.0 -1.9 3.1 -2.5 2.6
Bilateral oophorectomy (both ovaries removed) 1.0 1.1 5.1 0.6 -1.5 -0.5 -2.3 -0.3 -0.9 -0.1 0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.3 1.7 -0.5 -0.1 0.4 1.3 -0.1 -0.4 0.2 -0.5
Tinnitus: Yes, but not now, but have in the past 1.6 1.7 5.8 -0.1 -1.5 -1.5 -0.8 0.9 -2.4 1.3 -0.6
Qualifications: CSEs or equivalent 0.2 0.2 0.5 0.6 0.3 -0.0 0.5 -0.2 -0.5 -0.3 0.7
Serious illness, injury or assault to yourself 0.4 0.5 1.3 0.3 0.9 0.8 1.2 -0.6 0.2 -0.5 0.6
High blood pressure 1.8 5.1 10.2 1.1 1.0 3.1 1.2 -2.4 3.2 -2.5 2.3
Hayfever, allergic rhinitis or eczema 3.8 8.2 22.1 2.5 1.9 2.4 0.6 -3.7 0.5 -3.7 4.7
Multivitamins +/- minerals 1.6 2.0 4.6 -2.0 -0.1 -0.7 0.3 2.0 0.4 2.2 -1.6
Stomach or abdominal pain in last month 2.0 2.5 6.0 -0.0 0.9 1.9 2.4 -1.2 1.9 -1.6 1.5
Supplements: Glucosamine 3.0 3.9 7.7 -2.5 -1.4 -1.9 0.1 2.5 -0.1 2.4 -2.8
Diverticular disease/diverticulitis (self-reported) 2.8 3.3 5.5 1.6 0.9 2.0 2.3 -1.7 1.4 -1.9 2.3
Medication: Atenolol 5.3 6.6 10.8 2.4 1.7 2.7 1.0 -3.1 2.4 -3.3 3.1
Medication: Levothyroxine sodium 2.4 4.0 8.1 0.9 1.6 1.7 2.3 -1.7 2.9 -2.0 2.3
Sitting height 1.2 8.5 14.6 3.8 3.8 3.2 0.7 -3.2 -0.9 -2.9 2.9
Chronic bronchitis/emphysema (father) 1.2 1.4 2.3 -1.2 -0.6 -1.5 -0.3 1.5 -0.6 1.4 -1.4
High blood pressure (mother) 0.5 0.7 2.5 0.5 -0.9 0.1 -1.6 -0.5 -0.3 -0.4 1.1
Body mass index (BMI) 1.2 5.0 7.8 -2.8 -2.1 -1.4 -1.7 2.5 -1.4 2.7 -2.6
Impedance of leg (left) 6.1 29.7 44.0 5.3 4.8 5.6 5.1 -6.2 3.3 -6.6 6.0
Leg predicted mass (left) 1.4 7.2 12.3 -1.8 -1.0 -2.4 -2.6 2.9 -3.4 3.5 -2.9
Trunk fat mass 0.2 0.8 4.3 -0.7 -0.2 0.0 -0.6 0.4 -2.1 0.7 -0.8
Waist circumference 0.1 0.2 0.4 0.4 0.5 0.6 0.6 -0.5 -0.6 -0.2 0.4
Number of incorrect matches in round 1.1 1.9 5.7 -0.9 -1.5 -1.5 -2.4 1.0 -0.8 0.9 -1.1
Past tobacco smoking 2.5 4.6 6.9 2.0 2.2 2.5 2.6 -2.2 1.2 -2.0 2.1
Alcohol usually taken with meals 2.0 3.2 8.0 1.8 1.4 1.2 0.3 -2.6 1.0 -2.8 1.9
Nervous feelings 3.4 6.4 14.9 2.2 1.0 2.7 2.3 -2.5 3.9 -2.5 2.3
Frequency of tenseness / restlessness in last 2 weeks 3.9 6.0 16.7 1.7 1.4 2.7 1.4 -2.5 4.1 -2.5 2.1
Hearing difficulty/problems with background noise 0.9 1.5 2.4 1.3 1.3 0.1 0.5 -1.5 1.4 -1.5 1.3
Hair/balding pattern: Pattern 2 4.0 5.1 8.2 1.7 1.5 2.4 2.9 -2.4 2.5 -2.5 1.8
Had menopause 0.2 0.3 1.0 -0.5 -0.7 -1.0 -0.3 0.1 -0.7 0.1 -0.2
Had other major operations 1.2 1.4 4.6 -0.6 -2.1 -0.3 -1.2 0.5 -1.8 1.0 -0.9
Forced vital capacity (FVC) 2.3 8.9 15.4 -2.2 -2.0 -3.9 -2.3 3.7 -2.3 3.6 -3.0
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 2.4 -1.4 -0.8 -0.4 0.2 0.9 -0.8 1.2 -1.5
Ever unenthusiastic/disinterested for a whole week 0.2 0.2 0.5 -0.4 -0.6 0.3 0.1 0.5 0.2 0.6 -0.7
Qualifications: None of the above 1.4 3.0 4.9 2.2 0.0 2.2 1.4 -2.0 -0.1 -2.1 1.8
Financial difficulties in last 2 years 0.7 0.9 1.9 0.0 -0.4 -1.2 0.4 1.1 -1.1 1.4 -1.2
Mouth/teeth dental problems 0.3 0.4 1.5 0.1 0.6 -1.2 -0.4 -0.1 -1.1 0.0 0.0
Heart attack 9.3 11.9 17.2 4.1 2.8 3.1 2.2 -4.1 2.3 -4.0 4.2
Allergy 2.0 4.7 12.0 -1.9 -1.5 -2.1 -0.7 2.6 -0.8 2.6 -3.5
Pain all over the body in last month 2.7 2.9 8.3 1.8 1.0 2.9 1.5 -2.1 0.3 -1.6 1.4
Diabetes (self-reported) 4.2 6.5 10.5 2.1 2.0 2.6 1.8 -3.0 2.0 -3.2 3.2
Hayfever/allergic rhinitis (self-reported) 1.3 1.7 5.5 0.9 0.5 1.3 0.4 -1.6 0.2 -1.7 2.3
Medication: Ramipril 5.0 6.4 11.4 2.3 2.3 2.4 1.4 -2.7 3.4 -2.5 2.7
Medication: Simvastatin 0.8 1.2 2.5 -0.4 -1.1 -1.6 -0.1 1.2 1.4 1.2 -0.8
Fluid intelligence score 4.4 9.2 19.8 -3.8 -1.5 -2.7 -2.2 3.5 -0.9 3.5 -4.5
Illnesses of siblings 0.3 0.4 1.4 -0.5 -0.7 -0.5 -1.2 0.5 -0.4 0.4 -0.6
Neuroticism score 2.5 5.3 22.1 1.4 1.0 2.4 1.1 -2.0 4.7 -2.0 1.5
Weight 0.4 2.0 6.7 -0.8 -0.5 -0.8 -1.4 1.2 -2.6 1.7 -1.4
Impedance of arm (right) 0.4 1.8 4.5 1.2 1.3 0.7 1.2 -1.8 -0.6 -2.1 1.2
Arm fat percentage (right) 1.0 4.1 6.6 -2.6 -1.9 -1.5 -1.5 1.9 -2.1 2.1 -2.4
Trunk fat-free mass 0.2 1.4 6.1 1.0 0.9 -0.4 -1.3 0.5 -2.5 1.1 -0.3
Hip circumference 3.7 15.8 21.5 -4.3 -3.4 -3.1 -3.4 4.1 -4.1 4.4 -4.6
Time employed in main current job 4.3 5.0 9.5 2.6 1.7 1.7 0.3 -2.9 0.4 -3.1 2.9
Alcohol intake versus 10 years previously 2.3 3.5 8.3 2.9 1.9 1.2 2.2 -1.9 0.1 -1.5 2.0
Father’s age at death 0.5 0.6 3.9 -0.4 -0.2 -0.4 -0.6 0.4 -2.0 0.6 -0.3
Worrier / anxious feelings 1.1 2.1 9.8 0.9 0.3 1.8 0.8 -0.9 3.1 -0.9 0.9
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.3 5.4 0.7 0.1 0.9 0.8 -1.1 2.3 -1.1 0.8
Falls in the last year 2.2 3.0 5.2 -1.7 -1.7 -1.7 -1.6 1.9 -0.5 1.9 -2.3
Hair/balding pattern: Pattern 3 0.4 0.6 2.2 -0.2 -1.5 -0.5 -1.3 0.5 -0.3 0.6 -0.2
Number of live births 2.1 3.0 8.8 -1.1 -0.8 -1.8 0.1 1.8 -3.0 2.1 -1.6
Forced expiratory volume in 1-second (FEV1) 0.6 1.9 5.2 -0.8 -0.4 -2.3 -0.7 1.9 -0.8 1.9 -1.2
Pulse rate 9.9 16.7 21.5 4.1 4.5 3.9 3.5 -4.5 2.7 -4.6 4.5
Happiness 2.5 3.0 5.2 1.6 0.7 1.7 1.2 -2.2 1.6 -2.0 2.3
Noisy workplace 1.3 1.6 3.2 1.4 0.6 1.8 1.1 -1.4 0.0 -1.4 1.5
Qualifications: A levels/AS levels or equivalent 0.3 0.7 1.7 -0.5 -0.2 -0.8 -0.8 0.5 -1.1 0.8 -1.3
Serious illness, injury or assault of a close relative in last 2 years 2.7 3.1 6.8 1.2 2.3 1.9 2.6 -1.4 1.2 -1.4 1.6
Mouth/teeth dental problems: Dentures 2.8 4.8 6.7 2.6 1.0 2.5 1.3 -2.5 1.8 -2.6 2.4
Asthma 1.0 1.9 4.1 0.8 0.7 2.0 1.3 -1.1 1.7 -1.2 1.6
Medication: Ibuprofen (e.g. Nurofen) 0.3 0.4 1.4 0.1 1.2 0.0 0.8 0.1 1.1 0.1 0.4
Medication: Cholesterol lowering 1.6 2.5 8.2 1.5 0.6 0.6 1.2 -1.4 2.9 -1.6 1.7
Depression (self-reported) 1.9 2.3 4.6 -1.4 -1.6 -1.1 -1.3 1.8 -0.1 1.8 -2.1
Medication: Lansoprazole 0.7 0.8 3.3 -0.5 -1.3 0.2 -1.8 0.1 0.9 -0.1 -0.1
Prospective memory result 0.8 1.0 3.5 0.6 -1.9 -0.3 -0.8 -0.3 -1.6 -0.2 0.4
Lung cancer (father) 1.1 1.3 3.6 1.9 -0.1 0.8 -0.5 -1.0 -1.5 -0.7 1.4
Illnesses of mother 0.6 0.7 2.0 -0.9 0.3 -0.5 0.2 1.0 -0.8 1.0 -1.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 1.1 3.4 -0.3 0.6 -1.8 -0.3 1.2 -1.1 1.4 -0.4
Pulse wave Arterial Stiffness index 0.6 0.7 2.6 -0.7 -1.1 -0.8 -1.6 0.5 0.0 0.1 0.2
Impedance of arm (left) 0.2 1.1 2.8 0.7 1.1 0.5 1.1 -1.3 -0.7 -1.7 0.7
Arm fat mass (right) 0.7 3.0 4.5 -1.9 -1.2 -1.1 -1.4 1.8 -2.1 2.0 -2.1
Trunk predicted mass 0.3 1.4 6.0 0.8 0.8 -0.5 -1.4 0.6 -2.4 1.2 -0.4
Standing height 0.8 8.1 20.3 4.5 3.5 1.6 0.6 -2.8 -2.8 -2.3 2.8
Length of working week for main job 3.5 3.9 10.7 2.1 2.0 3.3 1.4 -2.2 -0.3 -1.7 1.5
Exposure to tobacco smoke at home 1.4 1.6 3.7 1.2 1.2 0.9 0.3 -1.9 -1.0 -1.7 1.0
Breastfed as a baby 0.4 0.5 1.4 0.2 -0.1 0.1 -1.2 -0.7 0.1 -0.9 1.2
Tense / ‘highly strung’ 2.6 4.3 11.9 1.4 1.3 2.9 1.5 -1.8 3.5 -1.9 1.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.8 1.3 2.9 -1.2 -0.2 -0.3 0.3 1.3 1.4 1.4 -1.7
Hair/balding pattern: Pattern 4 0.9 2.2 3.9 -2.0 -1.1 -0.3 -1.3 1.5 -1.8 1.6 -1.6
Birth weight of first child 2.8 5.1 13.6 -1.5 -0.3 -1.9 0.7 2.2 -3.7 3.1 -2.5
Peak expiratory flow (PEF) 0.1 0.2 0.6 -0.3 0.1 -0.8 -0.0 0.5 -0.2 0.4 0.3
Pulse wave reflection index 7.1 8.8 12.2 -2.7 -2.8 -3.3 -3.3 3.5 -1.3 3.4 -2.9
Ever highly irritable/argumentative for 2 days 0.3 0.4 1.4 0.6 0.0 1.1 1.2 -0.3 -0.2 -0.1 0.2
Loud music exposure frequency 0.5 0.6 2.4 0.7 -0.5 0.3 -1.1 -0.4 -1.5 0.1 -0.3
Qualifications: O levels/GCSEs or equivalent 1.3 2.1 6.0 -1.9 -0.9 -2.4 -1.6 1.4 0.3 1.1 -0.8
Mouth/teeth dental problems: Bleeding gums 1.2 1.5 2.7 -1.1 -0.9 -0.2 -0.9 1.4 -1.6 1.6 -1.5
Blood clot in the leg (DVT) 0.2 0.3 1.0 0.7 0.2 1.0 0.7 -0.5 -0.4 -0.1 0.1
Medication: Paracetamol 0.4 0.7 1.9 0.3 0.7 0.8 1.0 -0.7 1.4 -0.9 0.8
Headache pain in last month 5.8 9.9 16.1 2.5 2.7 3.6 4.0 -2.9 3.0 -3.0 3.2
Medication for cholesterol, blood pressure or diabetes 1.6 2.7 9.5 -1.3 -0.2 -1.2 -0.5 1.6 -3.1 1.8 -1.6
Glaucoma (self-reported) 0.7 0.9 1.5 0.7 1.2 1.1 1.2 -0.9 -0.9 -0.7 0.4
Gout (self-reported) 0.4 0.5 3.5 0.4 -0.2 0.3 -0.4 -0.3 1.9 -0.4 -0.2
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 3.9 0.0 1.2 0.9 1.3 -0.4 2.0 -0.8 1.2
Medication: Amlodipine 0.4 0.5 1.3 0.3 -0.3 1.2 1.0 -0.5 0.7 -0.5 0.6
Medication: Ventolin 100micrograms inhaler 0.4 0.5 1.6 0.1 -0.5 0.8 1.2 -0.6 0.2 -0.7 0.7
Birth weight 0.6 1.3 4.9 0.7 -0.7 -1.1 -0.7 0.6 -2.2 1.1 -1.1
Chronic bronchitis/emphysema (mother) 0.2 0.3 0.7 -0.3 -0.8 0.2 0.2 0.4 0.3 0.6 -0.8
High blood pressure (siblings) 0.3 0.4 1.2 -0.6 -0.1 -0.6 -1.1 0.8 -0.1 0.5 -0.6
Forced vital capacity (FVC), Best measure 1.1 3.9 8.2 -1.3 -0.5 -2.9 -1.5 2.5 -2.1 2.5 -1.7
Body fat percentage 0.1 0.4 1.2 -1.1 -0.6 0.3 -0.3 0.2 -1.1 0.2 -0.6
Leg fat percentage (right) 0.1 0.3 1.3 -0.1 0.1 1.2 0.6 -0.6 0.0 -0.6 0.4
Arm fat-free mass (right) 0.2 1.0 4.3 0.3 0.5 -0.1 -1.1 0.7 -2.1 1.2 -0.4
Exposure to tobacco smoke outside home 1.9 2.6 6.7 1.0 0.7 2.6 0.7 -1.5 2.2 -1.6 1.5
Comparative body size at age 10 3.2 8.8 12.4 -3.0 -2.4 -3.5 -2.7 3.3 -1.4 3.2 -3.5
Number of full brothers 0.7 0.9 3.8 -0.7 0.1 -0.3 2.0 0.8 -0.5 1.0 -0.7
Worry too long after embarrassment 1.2 2.1 7.5 0.5 0.8 1.6 1.4 -1.2 2.7 -1.2 0.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.7 1.7 -0.5 -0.0 1.3 1.2 0.1 1.3 0.3 -0.6
Wheeze or whistling in the chest in last year 0.4 0.6 1.2 0.5 0.6 0.8 1.1 -0.6 1.0 -0.6 0.9
Number of children fathered 1.1 1.2 2.2 1.0 0.7 1.3 0.1 -1.4 1.1 -1.5 1.0
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.2 0.8 -0.4 -0.9 -0.2 -0.6 0.4 0.2 0.3 -0.1
Age at first live birth 1.7 3.0 6.6 1.3 2.0 1.2 1.8 -1.5 2.6 -1.7 1.4
Pulse wave peak to peak time 0.6 0.7 2.1 1.0 1.1 0.7 1.5 -0.7 -0.3 -0.3 -0.1
Health satisfaction 6.0 7.8 12.6 1.6 1.0 3.2 1.9 -3.2 3.2 -3.4 3.5
Shortness of breath walking on level ground 0.3 0.3 1.6 -0.2 0.7 -0.0 1.3 0.1 0.5 0.0 -0.1
Qualifications: College or University degree 0.9 3.0 7.3 -2.7 -0.6 -0.7 -1.5 2.0 0.5 1.8 -2.5
Eye problems/disorders: None of the above 1.7 2.0 4.1 -0.8 -1.2 -2.0 -1.4 1.6 -0.9 1.7 -1.3
Mouth/teeth dental problems: Loose teeth 0.5 0.6 2.0 -0.0 -0.9 0.7 1.0 -0.5 1.4 -0.5 0.6
Emphysema/chronic bronchitis 0.4 0.4 0.9 0.2 0.5 -0.9 0.3 0.8 -0.2 1.0 -0.8
Medication for pain relief, constipation, heartburn 0.5 0.8 1.5 -0.7 -1.0 -0.4 -0.7 0.8 -0.8 1.1 -1.2
Neck or shoulder pain in last month 0.7 1.0 2.3 0.9 0.0 0.4 1.5 -1.2 0.6 -1.2 1.2
Medication: Blood pressure 1.2 2.2 8.3 0.6 0.2 1.6 0.4 -1.3 2.9 -1.5 1.4
Angina (self-reported) 2.4 3.1 6.2 2.5 0.4 0.4 0.9 -2.3 0.9 -2.4 2.4
Migraine (self-reported) 2.1 2.6 4.6 1.1 2.1 2.1 1.7 -1.3 1.2 -1.4 1.6
Medication: Ibuprofen 0.4 0.4 1.8 0.3 0.6 0.3 0.9 -0.2 1.3 -0.2 0.5
Medication: Allopurinol 0.7 0.9 4.1 0.9 0.3 0.5 -0.7 -0.9 2.0 -0.9 -0.0
Medication: Omeprazole 2.6 3.0 7.7 -1.8 -2.0 -0.9 -0.5 1.7 -2.8 1.7 -1.6
Medication: Seretide 50 evohaler 0.2 0.2 1.1 -1.0 -0.7 0.1 -0.0 0.2 0.0 0.3 -0.1
Mean time to correctly identify matches 5.0 9.5 20.6 3.2 1.2 1.9 0.9 -4.2 1.5 -4.5 4.4
Heart disease (mother) 1.3 1.6 2.7 1.1 1.5 1.5 0.8 -1.4 0.4 -1.7 1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.5 0.9 0.6 -0.0 0.8 0.8 -0.8 0.6 -0.9 1.0
Whole body fat mass 0.2 0.9 3.6 -0.9 -0.4 -0.2 -0.7 0.7 -1.9 0.9 -1.0
Leg fat mass (right) 0.2 0.7 2.2 -0.9 -0.2 -0.1 -0.5 0.7 -1.5 1.0 -1.1
Arm predicted mass (right) 0.1 0.8 3.4 0.2 0.4 -0.1 -1.0 0.6 -1.9 1.0 -0.1
Pulse rate, automated reading 6.7 21.6 36.1 5.2 3.8 4.1 3.7 -5.3 3.2 -5.2 6.0
Alcohol intake frequency. 2.8 6.5 15.7 2.3 1.5 3.0 4.0 -2.6 0.4 -2.3 2.7
Comparative height size at age 10 1.1 6.0 12.2 3.5 2.5 0.7 0.2 -2.6 -3.0 -2.4 2.8
Number of full sisters 0.9 1.1 2.6 1.3 0.8 0.5 1.5 -0.5 -1.6 -0.3 1.1
Suffer from ‘nerves’ 2.0 3.2 7.4 1.1 0.7 2.4 1.2 -1.8 2.7 -1.8 1.7
Overall health rating 6.7 14.4 17.1 3.3 3.3 3.8 4.0 -4.0 3.6 -4.1 4.1
Chest pain or discomfort 0.3 0.4 1.0 -0.6 -1.0 -1.0 -0.1 0.5 -0.6 0.4 0.2
Had major operations 1.7 2.0 4.6 -1.9 -0.7 -1.7 0.5 1.6 0.1 1.4 -2.1
Age at last live birth 0.7 1.0 2.4 0.5 1.4 0.4 1.1 -0.7 1.6 -0.8 0.5
Family relationship satisfaction 0.4 0.5 1.5 0.0 0.9 0.2 0.9 -0.4 1.2 -0.2 0.6
Leg pain on walking 0.2 0.2 0.9 0.1 0.2 -0.6 1.0 -0.4 -0.0 -0.3 0.2
Qualifications: NVQ or HND or HNC or equivalent 1.6 2.0 6.3 2.5 1.2 0.3 0.5 -1.6 -0.1 -1.6 1.5
Commuting to job workplace: Car/motor vehicle 1.0 1.1 2.8 1.4 0.9 1.7 0.2 -1.0 0.9 -1.0 0.9
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 2.7 -0.6 -1.1 -0.6 -1.6 0.0 -0.2 -0.0 -0.3
Medication: Aspirin 1.0 1.3 3.1 1.3 0.7 0.7 -0.0 -1.4 0.7 -1.5 1.8
Supplements: Vitamin C 1.6 1.9 3.3 0.6 0.9 1.8 1.3 -1.3 1.6 -1.5 1.5
Knee pain experienced in last month 2.2 3.5 6.8 2.6 1.5 1.2 1.9 -2.3 0.4 -2.2 1.9
Hypertension (Self-reported) 1.9 5.3 9.8 1.4 1.2 3.0 1.3 -2.6 3.1 -2.6 2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 2.3 -0.7 0.1 1.2 0.7 -0.3 1.5 -0.4 -0.2
Illnesses of father: Heart disease 0.9 1.3 3.9 0.4 0.1 1.4 2.0 -0.8 1.6 -0.7 0.4
Illnesses of siblings: Diabetes 4.6 5.6 9.3 2.6 1.5 1.7 2.1 -3.0 1.5 -2.8 3.1
Smoking status: Previous 3.3 5.0 8.2 -2.0 -1.7 -2.9 -2.0 2.7 -1.0 2.5 -2.5
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.1 5.9 2.4 2.2 -0.2 0.5 -0.8 -1.8 -0.8 1.0
Whole body fat-free mass 0.4 2.4 8.0 -0.0 0.2 -1.1 -1.8 1.3 -2.8 1.9 -1.1
Leg fat-free mass (right) 1.1 6.0 11.6 -1.5 -0.8 -2.2 -2.3 2.5 -3.4 3.2 -2.6
Arm fat percentage (left) 1.1 4.3 7.3 -2.7 -1.8 -1.5 -1.4 2.0 -2.1 2.2 -2.6
Average weekly red wine intake 0.8 1.1 5.4 -0.3 -0.7 -1.3 -2.3 -0.2 -1.0 -0.5 -0.4
Handedness (chirality/laterality): Left-handed 0.6 0.7 1.5 -0.0 1.2 1.2 1.1 -0.3 1.1 -0.4 0.1
Mood swings 0.6 1.1 7.9 -0.1 -0.6 -0.2 -0.5 0.0 2.8 -0.1 -0.5
Loneliness, isolation 0.7 1.0 7.3 0.0 -0.2 0.8 0.0 -0.3 2.7 -0.3 0.3
Long-standing illness, disability or infirmity 1.7 2.6 3.8 1.1 0.4 1.8 1.9 -1.9 1.6 -2.0 1.8
Ever had bowel cancer screening 5.0 5.8 8.9 -2.2 -2.6 -3.0 -2.0 2.6 -0.6 2.6 -2.8
Diabetes diagnosed by doctor 3.6 5.9 10.1 2.3 1.9 2.5 1.7 -2.8 1.5 -2.9 3.2
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.6 1.1 -1.1 -0.8 -0.2 -0.7 1.0 -0.8 0.9 -0.6
Friendships satisfaction 0.3 0.4 2.5 -0.5 0.0 0.6 -0.1 -0.3 1.6 -0.1 0.1
Qualifications: nursing, teaching 0.9 1.4 3.7 -1.0 0.2 -0.7 -0.1 1.2 -1.4 1.6 -1.9
Commuting to job workplace: Walk 0.7 0.8 1.7 -1.3 -0.0 -1.2 -0.3 0.8 -1.3 0.6 -0.4
Eye problems/disorders: Cataract 1.0 1.1 2.5 0.9 0.3 1.3 -0.2 -1.6 0.1 -1.6 1.2
Mouth/teeth dental problems: Mouth ulcers 2.6 4.1 7.6 -1.6 -1.9 -2.8 -1.9 2.1 -1.5 1.9 -2.3
Medication for cholesterol 1.7 2.6 5.7 -0.5 -0.3 -1.7 -0.6 1.7 -2.4 2.0 -2.1
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.9 3.5 4.6 -1.8 -1.6 -2.1 -2.1 1.7 -1.4 1.9 -2.1
Back pain experienced in last month 2.3 3.4 9.3 0.9 0.9 2.0 2.3 -1.5 3.0 -1.4 1.6
Mineral and other dietary supplements 1.3 1.7 3.0 1.5 1.1 1.2 -0.5 -1.6 0.1 -1.7 1.6
Breast cancer (self-reported) 0.5 0.6 4.1 0.7 -0.4 -0.4 -2.0 -0.2 -0.3 -0.1 0.1
Asthma (self-reported) 0.8 1.7 4.0 0.9 0.7 2.0 1.3 -1.1 1.3 -1.1 1.4
Osteoporosis (self-reported) 6.3 7.7 12.1 -2.3 -3.5 -2.7 -2.4 2.8 -2.4 3.0 -3.1
Osteoarthritis (self-reported) 0.9 1.1 2.9 -0.7 -1.7 -1.1 -0.8 0.6 -0.9 0.6 -1.5
Medication: Aspirin 1.1 1.5 3.7 1.2 0.2 0.7 -0.2 -1.6 0.5 -1.9 1.9
Medication: Gliclazide 1.8 2.1 4.8 0.4 1.3 2.2 1.8 -0.8 2.1 -1.0 0.8
Illnesses of father: None of the above (group 1) 0.7 0.8 3.2 -0.1 -0.7 -0.6 -1.6 0.1 -1.8 0.0 0.3
Smoking status: Current 0.5 0.8 1.5 0.9 0.8 0.7 0.6 -1.2 -0.8 -0.9 1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.5 1.4 -0.5 0.2 -1.2 -0.1 0.9 0.4 1.0 -0.8
Whole body water mass 0.4 2.4 7.8 -0.0 0.2 -1.1 -1.8 1.3 -2.8 1.9 -1.1
Leg predicted mass (right) 1.2 6.2 11.3 -1.5 -0.9 -2.2 -2.4 2.6 -3.4 3.3 -2.7
Arm fat mass (left) 0.8 3.2 4.8 -2.0 -1.3 -1.1 -1.5 1.8 -2.2 2.1 -2.1
Number of self-reported non-cancer illnesses 6.5 11.3 17.2 2.8 2.1 4.2 2.9 -3.7 3.2 -3.8 3.8
Average weekly champagne plus white wine intake 1.1 1.5 2.9 -1.4 -1.1 -0.5 -1.7 1.1 -0.9 1.1 -1.6
Miserableness 1.0 1.7 11.4 -0.2 -0.6 -0.7 -0.7 0.3 3.4 0.1 -0.7
Guilty feelings 0.8 1.2 4.1 -1.4 0.0 -0.2 -0.1 0.8 2.0 0.9 -1.6
Wears glasses or contact lenses 0.5 0.6 2.1 0.8 0.9 0.1 1.4 -0.8 0.0 -0.8 0.3
Ever taken oral contraceptive pill 0.3 0.4 1.4 -0.4 0.7 -0.6 -0.5 0.3 -1.2 0.3 0.2
Hearing aid user 0.6 0.6 1.2 0.2 1.0 -0.2 0.3 -0.8 0.9 -1.0 1.1
Mother’s age at death 3.0 3.8 7.1 -1.5 -0.5 -2.5 -0.5 2.0 -2.7 2.1 -2.5
Financial situation satisfaction 1.5 1.8 3.3 -1.2 -0.9 -1.8 -1.7 1.4 -0.6 1.6 -1.2
Tinnitus: Yes, now most or all of the time 1.2 1.4 2.2 -1.1 -1.1 -1.3 0.3 1.3 1.3 1.2 -1.5
Commuting to job workplace: Public transport 0.5 0.6 1.9 -0.8 -0.3 -1.4 -0.9 0.8 -0.2 0.7 -0.8
Eye problems/disorders: Glaucoma 0.6 0.7 2.0 0.4 0.7 1.4 0.6 -0.9 -0.4 -0.8 0.7
Medication: Blood pressure 2.1 4.0 8.1 1.0 0.4 2.6 1.7 -2.0 2.8 -2.0 2.4
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.6 -0.3 -0.7 -0.7 0.2 0.6 0.1 0.6 -0.4
Supplements: Fish oil (including cod liver oil) 0.4 0.6 2.0 -0.9 -0.0 -0.4 0.2 0.9 1.4 0.8 -0.4
High cholesterol (Self-reported) 1.8 3.1 10.5 1.5 0.7 1.1 1.2 -1.5 3.2 -1.6 2.1
Medication: Bendroflumethiazide 3.3 5.1 9.1 1.0 1.6 3.0 2.0 -2.3 2.5 -2.4 2.5
Medication: Paracetamol 0.2 0.3 0.7 0.6 -0.1 0.2 0.4 -0.6 0.8 -0.8 0.5
Medication: Lisinopril 1.3 1.7 2.4 -1.1 -1.4 -1.5 -1.0 1.5 -0.4 1.5 -1.4
Medication: Atorvastatin 4.5 5.5 8.8 1.4 1.5 2.9 1.1 -2.4 2.8 -2.9 3.0
Illnesses of father: High blood pressure 0.3 0.4 1.5 -0.5 0.2 -0.6 -0.2 0.8 0.2 0.8 -1.2
Alcohol drinker status: Never 1.5 1.7 3.1 1.3 0.0 1.8 1.6 -1.2 -1.7 -1.1 1.0
Ever smoked 0.9 1.6 5.8 -0.8 -1.5 -1.5 -2.4 0.7 -0.7 0.6 -0.8
Basal metabolic rate 0.4 2.4 8.0 -0.2 0.1 -0.9 -1.6 1.3 -2.8 2.0 -1.3
Leg fat percentage (left) 0.1 0.5 1.6 0.0 0.0 1.3 0.5 -0.9 0.2 -1.0 0.6
Arm fat-free mass (left) 0.1 0.6 2.6 0.4 0.3 0.2 -1.1 0.4 -1.6 0.9 -0.0
Number of operations (self-reported) 1.5 2.3 4.0 -0.9 -2.0 -1.5 -1.7 1.1 -1.6 1.3 -1.7
Average weekly beer plus cider intake 0.4 0.6 2.8 0.1 0.4 0.7 1.7 0.6 0.4 0.7 -0.6
Irritability 0.4 0.7 4.6 -0.3 0.3 0.8 0.1 -0.6 2.1 -0.5 -0.0
Risk taking 0.4 0.6 3.7 -0.2 1.9 0.2 0.2 0.2 -0.9 0.4 -0.5
Ever had prostate specific antigen (PSA) test 0.0 0.0 0.1 0.4 -0.1 0.3 -0.2 -0.1 0.2 -0.1 -0.0
Fractured/broken bones in last 5 years 0.2 0.2 1.2 -0.1 -0.5 0.0 0.0 0.4 0.2 0.5 -1.1
Age started oral contraceptive pill 2.2 2.8 5.3 1.9 1.7 1.0 1.0 -2.3 0.0 -2.2 2.0
Diastolic blood pressure, automated reading 0.7 2.3 5.2 1.4 2.1 2.3 0.4 -1.5 1.0 -1.4 1.1
Ever depressed for a whole week 0.2 0.2 0.6 0.4 0.5 0.3 0.8 0.4 0.6 0.4 -0.1
Unable to work because of sickness or disability 1.3 1.7 2.9 1.7 0.5 1.3 1.3 -1.5 0.4 -1.7 1.4
Commuting to job workplace: Cycle 0.1 0.1 0.2 0.5 0.1 -0.2 -0.3 -0.4 0.1 -0.3 0.2
Myopia 4.9 7.1 9.4 3.0 2.8 2.4 3.1 -2.9 1.6 -2.6 2.6
Vascular/heart problems diagnosed by doctor 2.8 7.5 11.3 -1.9 -1.4 -3.1 -1.7 3.1 -3.4 3.3 -3.2
Cholesterol lowering medication 0.9 1.4 8.1 -0.2 -1.1 0.3 -0.0 -0.1 2.9 -0.4 1.1
Medication: Omeprazole (e.g. Zanprol) 1.7 2.1 5.1 -1.8 -1.6 -0.7 -0.4 1.5 -2.3 1.4 -1.3
Pain experienced in last month 7.2 11.9 16.7 -3.0 -2.4 -4.1 -4.0 3.5 -3.5 3.5 -3.5
Supplements: Calcium 0.9 1.0 2.3 -1.1 -0.6 0.3 0.2 1.0 -1.5 1.0 -1.3
Basal cell carcinoma (self-reported) 1.7 2.0 3.7 -0.8 -0.8 -1.9 -1.7 1.4 -0.9 1.5 -1.9
Heart attack/myocardial infarction (self-reported) 8.7 11.2 17.0 4.1 2.6 2.8 2.0 -4.1 2.3 -4.0 4.0
Deep venous thrombosis (DVT) (self-reported) 0.2 0.3 1.0 0.5 0.0 1.0 0.5 -0.4 -0.7 0.0 0.0
Heart disease (siblings) 4.4 5.4 6.5 2.0 2.2 2.2 2.4 -2.5 2.4 -2.5 2.4
Alcohol drinker status: Previous 2.6 2.9 5.3 -2.3 -1.8 -1.2 -0.5 2.2 -0.7 2.2 -1.8
Pack years of smoking 1.9 2.7 6.9 1.1 0.7 1.1 0.5 -2.2 1.1 -2.6 2.4
Impedance of whole body 2.1 10.6 18.5 2.9 2.8 3.2 3.2 -3.8 1.6 -4.3 3.5
Leg fat mass (left) 0.1 0.6 1.6 -0.8 -0.2 -0.0 -0.5 0.6 -1.3 0.8 -0.9
Arm predicted mass (left) 0.1 0.6 2.5 0.6 0.7 0.3 -0.8 0.2 -1.6 0.7 0.1