Best TWAS P=6.57e-08 · Best GWAS P=8.41e-08 conditioned to 0.199
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellum | RCCD1 | 0.45 | 0.29 | lasso | 6 | 0.31 | 8.9e-10 | 4.9 | 5.2 | 1.7e-07 | 0.85 | 0.02 | 0.98 | FALSE |
2 | GTEx | Brain Frontal Cortex BA9 | RCCD1 | 0.43 | 0.29 | lasso | 6 | 0.28 | 5.7e-08 | 5.0 | 5.4 | 6.6e-08 | 0.88 | 0.01 | 0.98 | TRUE |
3 | GTEx | Lung | RCCD1 | 0.14 | 0.09 | lasso | 3 | 0.06 | 1.2e-05 | 5.1 | 5.2 | 2.5e-07 | 0.81 | 0.02 | 0.98 | FALSE |
4 | GTEx | Testis | RCCD1 | 0.60 | 0.52 | lasso | 4 | 0.52 | 2.6e-26 | 5.1 | 5.2 | 2.1e-07 | 0.87 | 0.01 | 0.98 | FALSE |
5 | NTR | Blood | RCCD1 | 0.02 | 0.02 | lasso | 2 | 0.01 | 1.2e-05 | 5.1 | 5.1 | 3.1e-07 | 0.82 | 0.02 | 0.98 | FALSE |
6 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | RCCD1 | 0.16 | 0.11 | lasso | 2 | 0.11 | 6.5e-12 | 5.0 | 5.3 | 1.3e-07 | 0.90 | 0.01 | 0.99 | FALSE |
7 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RCCD1 | 0.18 | 0.12 | lasso | 3 | 0.12 | 1.1e-13 | 5.0 | 5.2 | 2.0e-07 | 0.88 | 0.02 | 0.98 | FALSE |