Best TWAS P=4.54e-09 · Best GWAS P=4.94e-10 conditioned to 0.0375
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 0.0008 | -6.0 | 5.9 | 4.5e-09 | -0.94 | 0.01 | 0.98 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 0.0614 | -5.5 | -5.8 | 8.8e-09 | 0.90 | 0.07 | 0.85 | FALSE |
| 3 | GTEx | Spleen | MLLT10 | 0.16 | 0.02 | lasso | 7 | 0.02 | 0.1030 | -5.5 | 5.7 | 1.3e-08 | -0.92 | 0.03 | 0.55 | FALSE |