Best TWAS P=2.01e-10 · Best GWAS P=1.14e-13 conditioned to 0.000106
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Colon Sigmoid | CCDC153 | 0.18 | 0.02 | enet | 18 | 0.14 | 8.0e-06 | -7.3 | 5.6 | 1.7e-08 | -0.58 | 0.02 | 0.74 | FALSE |
2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | DDX6 | 0.26 | 0.09 | lasso | 3 | 0.08 | 9.6e-04 | -5.9 | 5.9 | 4.3e-09 | -0.62 | 0.01 | 0.48 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | DDX6 | 0.05 | 0.03 | blup | 14 | 0.03 | 1.2e-03 | -6.9 | 6.4 | 2.0e-10 | -0.81 | 0.00 | 0.96 | TRUE |