[Hub]/) : Traits : Primary Biliary Cirrhosis : ← →

chr11:63,316,786-64,820,283

Best TWAS P=2.77e-09 · Best GWAS P=1.68e-09 conditioned to 0.147

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPP1R14B 0.10 0.09 lasso 5 0.09 1.1e-10 -5.5 5.4 8.3e-08 -0.92 0.05 0.95 FALSE
2 GTEx Artery Tibial PPP1R14B 0.21 0.13 lasso 4 0.13 4.0e-10 -5.6 5.6 1.8e-08 -0.94 0.03 0.97 FALSE
3 GTEx Brain Cerebellar Hemisphere CCDC88B 0.45 0.39 lasso 3 0.41 1.2e-11 -5.6 5.8 5.5e-09 -0.97 0.01 0.99 FALSE
4 GTEx Brain Cerebellum CCDC88B 0.48 0.55 lasso 4 0.54 1.6e-18 -5.6 5.7 1.3e-08 -0.95 0.03 0.97 FALSE
5 GTEx Brain Frontal Cortex BA9 CCDC88B 0.23 0.10 lasso 10 0.09 2.4e-03 -5.8 5.9 2.8e-09 -0.92 0.02 0.97 TRUE
6 GTEx Skin Sun Exposed Lower leg CCDC88B 0.11 0.05 enet 14 0.05 2.5e-05 -5.5 5.3 1.1e-07 -0.82 0.02 0.98 FALSE
7 ROSMAP Brain Pre-frontal Cortex CCDC88B 0.33 0.39 lasso 9 0.40 1.1e-54 -6.0 5.8 7.3e-09 -0.98 0.01 0.99 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma CCDC88B 0.02 0.02 enet 9 0.02 2.4e-05 -5.2 5.5 4.0e-08 -0.94 0.01 0.99 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC88B 0.03 0.04 lasso 2 0.03 1.3e-04 -5.7 5.7 1.1e-08 -0.95 0.01 0.98 FALSE