| Depressed Affect (Nagel 2018) |
1.09 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Neuroticism (Nagel 2018) |
0.95 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Worry (Nagel 2018) |
1.08 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Alzheimer’s Disease (in mother) |
1.73 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
CTSH SLC26A1 |
| Alzheimer’s Disease (including proxy) |
1.62 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SLC26A1 |
| Crohns Disease (2017) |
3.84 |
6 |
3 |
6.7 |
0.65 |
0.15829 |
CCDC88B DENND1B GSDMB IL12RB2 RMI2 SYNGR1 |
| Irritable Bowel Disease (IBD) |
4.57 |
7 |
4 |
8.9 |
0.65 |
0.11556 |
CCDC88B DENND1B GSDMB IL12RB2 IRF5 RMI2 SYNGR1 |
| Ulcerative Colitis (UC) |
3.88 |
5 |
1 |
2.2 |
0.60 |
0.20360 |
GSDMB IL12RB2 IRF5 SLC9B1 SYNGR1 |
| Reaction Time |
2.00 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
CARM1 SH2B3 |
| Prostate Cancer |
2.37 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
TRIM59 |
| Coronary Artery Disease (CAD) |
1.63 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Crohns Disease (2012) |
2.98 |
4 |
0 |
0.0 |
0.38 |
0.61698 |
CCDC88B GSDMB IL12RB2 RMI2 |
| Fasting Glucose |
2.58 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SLC9B1 |
| HDL Cholesterol |
2.02 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
GSDMB SYNGR1 |
| LDL Cholesterol |
4.53 |
3 |
1 |
2.2 |
0.00 |
1.00000 |
CARM1 SH2B3 TRIM59 |
| Lupus |
10.85 |
5 |
1 |
2.2 |
0.92 |
0.00976 |
DEXI GSDMB IL12A IL12RB2 IRF5 |
| Rheumatoid Arthritis |
5.13 |
4 |
1 |
2.2 |
0.99 |
0.00725 |
DDX6 GSDMB SH2B3 SYNGR1 |
| Ulcerative Colitis |
3.14 |
3 |
1 |
2.2 |
0.00 |
1.00000 |
GSDMB IL12RB2 IRF5 |
| Blood Eosinophil Count |
12.05 |
10 |
6 |
13.3 |
0.28 |
0.39726 |
CARM1 CCDC88B DDX6 DENND1B DEXI GSDMB IL7R IRF5 SH2B3 SLC9B1 |
| Blood Platelet Count |
2.13 |
9 |
5 |
11.1 |
0.25 |
0.52456 |
GSDMB INPP1 IRF5 KPNA4 RMI2 SH2B3 SMC4 SYNGR1 TRIM59 |
| Blood Red Count |
1.64 |
4 |
1 |
2.2 |
0.08 |
0.88213 |
KPNA4 SH2B3 SLC9B1 TRIM59 |
| Blood White Count |
8.95 |
7 |
2 |
4.4 |
0.13 |
0.78375 |
CARM1 DDX6 DEXI GSDMB IL7R SH2B3 SLC9B1 |
| Heel T-Score |
1.22 |
8 |
1 |
2.2 |
-0.46 |
0.21698 |
CCDC88B DDX6 IL12A IL12RB2 IRF5 KPNA4 SMC4 TRIM59 |
| BMI |
0.56 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Height |
0.37 |
5 |
2 |
4.4 |
-0.22 |
0.71605 |
CARM1 IL7R INPP1 SH2B3 SYNGR1 |
| Waist Hip Ratio (WHR) |
0.96 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SLC26A1 |
| Systolic Blood Pressure |
3.74 |
4 |
4 |
8.9 |
0.98 |
0.00036 |
KPNA4 SH2B3 SMC4 TRIM59 |
| Smoking Status |
1.03 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
CCDC88B |
| Allergy or Eczema |
7.32 |
6 |
4 |
8.9 |
0.18 |
0.73297 |
DDX6 DEXI GSDMB IL7R SH2B3 SLC9B1 |
| Cardiovascular Disease |
3.62 |
7 |
2 |
4.4 |
0.81 |
0.01577 |
CARM1 CCDC88B KPNA4 SH2B3 SLC26A1 SMC4 TRIM59 |
| Hypothyroidism (self reported) |
8.47 |
7 |
3 |
6.7 |
0.67 |
0.07106 |
CCDC88B IL12A IL12RB2 IL7R IRF5 SH2B3 SYNGR1 |
| Respiratory disease |
7.17 |
3 |
3 |
6.7 |
0.00 |
1.00000 |
DEXI GSDMB IL7R |
| Type 2 Diabetes (T2D) (2018) |
1.72 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 TRIM59 |
| Lung FEV1/FVC ratio |
0.75 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
GSDMB IL7R |
| Lung FVC |
0.83 |
3 |
0 |
0.0 |
0.00 |
1.00000 |
DEXI GSDMB SH2B3 |
| Neuroticism |
1.00 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Chronotype (morning person) |
1.61 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
IL12RB2 KPNA4 |
| Hair Pigment |
0.22 |
3 |
2 |
4.4 |
0.00 |
1.00000 |
CARM1 SH2B3 SYNGR1 |
| Tanning |
0.37 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 SYNGR1 |
| Number of treatments/medications taken |
3.28 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 TRIM59 |
| Sensitivity / hurt feelings |
0.99 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Other serious medical condition/disability diagnosed by doctor |
1.71 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DEXI |
| Ever used hormone-replacement therapy (HRT) |
2.49 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
TRIM59 |
| Systolic blood pressure, automated reading |
3.01 |
5 |
2 |
4.4 |
0.87 |
0.02579 |
KPNA4 SH2B3 SLC26A1 SMC4 TRIM59 |
| Impedance of leg (right) |
0.95 |
3 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B KPNA4 TRIM59 |
| Leg fat-free mass (left) |
0.78 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Trunk fat percentage |
0.74 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SLC26A1 |
| Hand grip strength (right) |
0.76 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
IRF5 |
| Maternal smoking around birth |
1.08 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
CCDC88B |
| Fed-up feelings |
1.96 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
CCDC88B SH2B3 |
| Taking other prescription medications |
3.72 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
GSDMB SH2B3 |
| Age when periods started (menarche) |
0.81 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SLC9B1 |
| Heel bone mineral density (BMD) T-score, automated (left) |
1.77 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DDX6 |
| High blood pressure |
3.15 |
3 |
1 |
2.2 |
1.00 |
0.00349 |
KPNA4 SH2B3 TRIM59 |
| Hayfever, allergic rhinitis or eczema |
7.46 |
5 |
4 |
8.9 |
0.23 |
0.70730 |
DDX6 DEXI GSDMB IL7R SLC9B1 |
| Medication: Atenolol |
2.16 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 |
| Medication: Levothyroxine sodium |
6.43 |
3 |
1 |
2.2 |
0.00 |
1.00000 |
CCDC88B IL7R SH2B3 |
| Sitting height |
0.55 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
CTSH RMI2 |
| Body mass index (BMI) |
0.82 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Impedance of leg (left) |
0.81 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Leg predicted mass (left) |
0.79 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Trunk fat mass |
0.70 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
SLC26A1 SYNGR1 |
| Waist circumference |
0.85 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SLC26A1 |
| Past tobacco smoking |
1.43 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
CCDC88B SH2B3 |
| Nervous feelings |
1.25 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Heel bone mineral density (BMD) T-score, automated (right) |
1.98 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
DDX6 KPNA4 |
| Mouth/teeth dental problems |
2.19 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
IRF5 |
| Heart attack |
1.55 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Allergy |
8.26 |
6 |
5 |
11.1 |
-0.10 |
0.85630 |
ARHGAP31 DDX6 DEXI GSDMB IL7R SLC9B1 |
| Diabetes (self-reported) |
2.00 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
TRIM59 |
| Hayfever/allergic rhinitis (self-reported) |
4.73 |
3 |
2 |
4.4 |
0.00 |
1.00000 |
DEXI GSDMB IL7R |
| Medication: Simvastatin |
2.24 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
CARM1 |
| Illnesses of siblings |
1.82 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Weight |
0.89 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 SYNGR1 |
| Impedance of arm (right) |
1.39 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 SLC9B1 |
| Arm fat percentage (right) |
0.62 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SLC26A1 |
| Trunk fat-free mass |
1.15 |
5 |
1 |
2.2 |
-0.39 |
0.52023 |
DDX6 IL12RB2 KPNA4 SH2B3 SYNGR1 |
| Hip circumference |
0.90 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 SYNGR1 |
| Father's age at death |
1.70 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 |
| Worrier / anxious feelings |
1.04 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Number of live births |
1.66 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SLC9B1 |
| Mouth/teeth dental problems: Dentures |
2.20 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
GSDMB |
| Asthma |
7.62 |
5 |
3 |
6.7 |
0.15 |
0.81051 |
CARM1 DDX6 DEXI GSDMB IL7R |
| Medication: Cholesterol lowering |
1.38 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
CARM1 |
| Illnesses of mother |
2.35 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
TRIM59 |
| Pulse wave Arterial Stiffness index |
1.50 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
CCDC88B |
| Impedance of arm (left) |
1.41 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 SLC9B1 |
| Arm fat mass (right) |
0.69 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B SLC26A1 |
| Trunk predicted mass |
1.16 |
5 |
1 |
2.2 |
-0.38 |
0.52544 |
DDX6 IL12RB2 KPNA4 SH2B3 SYNGR1 |
| Standing height |
0.46 |
4 |
1 |
2.2 |
-0.50 |
0.49824 |
CARM1 CTSH SH2B3 SYNGR1 |
| Seen doctor (GP) for nerves, anxiety, tension or depression |
1.40 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Birth weight of first child |
2.57 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 |
| Blood clot in the leg (DVT) |
1.19 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Medication for cholesterol, blood pressure or diabetes |
2.56 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
CARM1 SH2B3 |
| Gout (self-reported) |
3.05 |
3 |
0 |
0.0 |
0.00 |
1.00000 |
CCDC88B IRF5 SH2B3 |
| Hypothyroidism/myxoedema (self-reported) |
7.01 |
5 |
1 |
2.2 |
0.71 |
0.18317 |
CCDC88B IL7R IRF5 SH2B3 SYNGR1 |
| Medication: Amlodipine |
1.54 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SLC26A1 |
| Medication: Ventolin 100micrograms inhaler |
4.28 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
DEXI GSDMB |
| Birth weight |
1.01 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 |
| High blood pressure (siblings) |
1.35 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Forced vital capacity (FVC), Best measure |
0.53 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
CARM1 |
| Body fat percentage |
0.81 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SLC26A1 |
| Leg fat percentage (right) |
0.92 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SLC26A1 |
| Arm fat-free mass (right) |
1.23 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 SYNGR1 |
| Exposure to tobacco smoke outside home |
1.47 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Comparative body size at age 10 |
1.54 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
TRIM59 |
| Wheeze or whistling in the chest in last year |
3.28 |
2 |
2 |
4.4 |
0.00 |
1.00000 |
DEXI GSDMB |
| Number of children fathered |
1.73 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B |
| Pulse wave peak to peak time |
1.41 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
CCDC88B |
| Qualifications: College or University degree |
1.55 |
4 |
0 |
0.0 |
-1.00 |
0.00155 |
CCDC88B KPNA4 SMC4 TRIM59 |
| Medication: Blood pressure |
3.09 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 |
| Medication: Allopurinol |
3.08 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
CCDC88B SH2B3 |
| Medication: Seretide 50 evohaler |
1.82 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
DEXI GSDMB |
| Mean time to correctly identify matches |
1.65 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 |
| Whole body fat mass |
0.74 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SLC26A1 |
| Leg fat mass (right) |
0.79 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SLC26A1 |
| Arm predicted mass (right) |
1.25 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 SYNGR1 |
| Alcohol intake frequency. |
1.97 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
SLC9B1 TRIM59 |
| Comparative height size at age 10 |
0.74 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 |
| Suffer from 'nerves' |
2.55 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
SMC4 TRIM59 |
| Overall health rating |
1.61 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
TRIM59 |
| Chest pain or discomfort |
1.13 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
GSDMB |
| Medication: Aspirin |
1.45 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Knee pain experienced in last month |
1.68 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
DEXI |
| Hypertension (Self-reported) |
2.92 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 TRIM59 |
| Illnesses of father: Heart disease |
1.36 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Smoking status: Previous |
1.56 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Whole body fat-free mass |
1.07 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 SYNGR1 |
| Leg fat-free mass (right) |
0.87 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Arm fat percentage (left) |
0.65 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SLC26A1 |
| Average weekly red wine intake |
1.31 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
GSDMB |
| Loneliness, isolation |
1.26 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Diabetes diagnosed by doctor |
2.17 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
TRIM59 |
| Mouth/teeth dental problems: Mouth ulcers |
11.34 |
10 |
6 |
13.3 |
-0.55 |
0.05026 |
DENND1B IL12A IL12RB2 IL7R IRF5 KPNA4 SH2B3 SLC9B1 SMC4 TRIM59 |
| Medication for cholesterol |
2.68 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 |
| Asthma (self-reported) |
7.68 |
5 |
3 |
6.7 |
0.18 |
0.76933 |
CARM1 DDX6 DEXI GSDMB IL7R |
| Osteoporosis (self-reported) |
1.30 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
CCDC88B |
| Illnesses of father: None of the above (group 1) |
1.81 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Forced expiratory volume in 1-second (FEV1), predicted percentage |
1.45 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
GSDMB |
| Whole body water mass |
1.08 |
4 |
1 |
2.2 |
-0.22 |
0.78182 |
DDX6 KPNA4 SH2B3 SYNGR1 |
| Leg predicted mass (right) |
0.86 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Arm fat mass (left) |
0.71 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
DENND1B SLC26A1 |
| Number of self-reported non-cancer illnesses |
4.17 |
4 |
2 |
4.4 |
0.61 |
0.27378 |
GSDMB KPNA4 SH2B3 TRIM59 |
| Miserableness |
1.18 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
GSDMB |
| Medication: Blood pressure |
1.75 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 |
| High cholesterol (Self-reported) |
3.08 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
CARM1 |
| Medication: Bendroflumethiazide |
1.45 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Medication: Lisinopril |
1.36 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Illnesses of father: High blood pressure |
1.24 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Ever smoked |
1.36 |
2 |
0 |
0.0 |
0.00 |
1.00000 |
CCDC88B SH2B3 |
| Basal metabolic rate |
1.02 |
3 |
1 |
2.2 |
0.00 |
1.00000 |
DDX6 SH2B3 SYNGR1 |
| Leg fat percentage (left) |
0.92 |
1 |
1 |
2.2 |
0.00 |
1.00000 |
SLC26A1 |
| Arm fat-free mass (left) |
1.31 |
4 |
1 |
2.2 |
-0.02 |
0.97928 |
DDX6 IL12RB2 SH2B3 SYNGR1 |
| Ever had prostate specific antigen (PSA) test |
1.62 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SLC26A1 |
| Diastolic blood pressure, automated reading |
3.30 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
INPP1 SH2B3 |
| Vascular/heart problems diagnosed by doctor |
3.09 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
SH2B3 TRIM59 |
| Cholesterol lowering medication |
3.21 |
2 |
1 |
2.2 |
0.00 |
1.00000 |
CARM1 SLC26A1 |
| Pain experienced in last month |
2.20 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Heart attack/myocardial infarction (self-reported) |
1.66 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Deep venous thrombosis (DVT) (self-reported) |
1.14 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SH2B3 |
| Impedance of whole body |
1.05 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SLC9B1 |
| Leg fat mass (left) |
0.82 |
1 |
0 |
0.0 |
0.00 |
1.00000 |
SLC26A1 |
| Arm predicted mass (left) |
1.28 |
3 |
1 |
2.2 |
0.00 |
1.00000 |
DDX6 SH2B3 SYNGR1 |