152 significantly associated models · 41 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 67074053 | 68559650 | 1 | 1 | 3.3e-21 | 7.5e-28 | 2.0e-08 | 74 | IL12RB2 |
2 | 1 | 196798989 | 198436809 | 1 | 1 | 1.9e-09 | 1.0e-11 | 1.1e-03 | 77 | DENND1B |
3 | 2 | 190521054 | 191931464 | 1 | 1 | 4.1e-10 | 2.3e-14 | 1.2e-05 | 67 | INPP1 |
4 | 3 | 118779507 | 119458851 | 2 | 2 | 4.2e-09 | 4.3e-15 | 1.3e-05 | 69 | ARHGAP31 KTELC1 |
5 | 3 | 159013779 | 160970437 | 5 | 7 | 1.7e-22 | 1.4e-23 | NaN | NaN | IL12A KPNA4 SMC4 TRIM59 |
6 | 4 | 258627 | 1694809 | 3 | 1 | 1.2e-07 | 2.7e-07 | 7.0e-02 | 88 | SLC26A1 |
7 | 4 | 102852939 | 104627833 | 4 | 1 | 8.2e-10 | 8.2e-10 | 1.0e+00 | 100 | SLC9B1 |
8 | 5 | 35608310 | 36124514 | 1 | 1 | 4.5e-09 | 4.7e-11 | 1.7e-03 | 77 | IL7R |
9 | 7 | 127878155 | 129284182 | 2 | 2 | 2.2e-23 | 5.1e-23 | 4.2e-04 | 87 | IRF5 |
10 | 11 | 63316786 | 64820283 | 2 | 1 | 2.8e-09 | 1.7e-09 | 1.5e-01 | 94 | CCDC88B |
11 | 11 | 118365263 | 119765318 | 2 | 1 | 2.0e-10 | 1.1e-13 | 1.1e-04 | 73 | DDX6 |
12 | 12 | 111154626 | 112582540 | 1 | 1 | 1.4e-07 | 3.2e-08 | 3.5e-03 | 72 | SH2B3 |
13 | 15 | 78520204 | 79933757 | 1 | 1 | 2.4e-07 | 1.6e-07 | 1.0e+00 | 100 | CTSH |
14 | 16 | 10329905 | 12138068 | 4 | 2 | 6.6e-14 | 2.4e-14 | 1.0e+00 | 100 | DEXI RMI2 |
15 | 17 | 37101380 | 39048774 | 8 | 1 | 3.2e-11 | 2.6e-11 | 1.0e-01 | 94 | GSDMB |
16 | 19 | 10283932 | 11730690 | 1 | 1 | 2.0e-07 | 1.0e-10 | 5.0e-10 | 7 | CARM1 |
17 | 22 | 39064209 | 40479448 | 1 | 1 | 6.7e-12 | 2.2e-11 | 4.4e-01 | 99 | SYNGR1 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Brain Putamen basal ganglia | 1 | 0.162 | 1.7 |
GTEx | Adrenal Gland | 1 | 0.070 | 1.6 |
GTEx | Brain Cortex | 2 | 0.196 | 1.6 |
GTEx | Brain Frontal Cortex BA9 | 1 | 0.110 | 1.6 |
GTEx | Breast Mammary Tissue (Male) | 2 | 0.171 | 1.6 |
GTEx | Liver | 0 | 0.000 | 1.6 |
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.6 |
GTEx | Uterus | 0 | 0.000 | 1.6 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 3 | 0.303 | 1.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 1 | 0.093 | 1.6 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 2 | 0.387 | 1.6 |
GTEx | Adipose Subcutaneous | 4 | 0.116 | 1.5 |
GTEx | Adipose Visceral Omentum | 1 | 0.050 | 1.5 |
GTEx | Artery Aorta | 1 | 0.034 | 1.5 |
GTEx | Artery Coronary | 2 | 0.171 | 1.5 |
GTEx | Brain Caudate basal ganglia | 1 | 0.110 | 1.5 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.5 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.5 |
GTEx | Brain Nucleus accumbens basal ganglia | 1 | 0.117 | 1.5 |
GTEx | Cells EBV-transformed lymphocytes | 2 | 0.143 | 1.5 |
GTEx | Cells Transformed fibroblasts | 6 | 0.145 | 1.5 |
GTEx | Colon Sigmoid | 2 | 0.139 | 1.5 |
GTEx | Colon Transverse | 2 | 0.098 | 1.5 |
GTEx | Esophagus Gastroesophageal Junction | 0 | 0.000 | 1.5 |
GTEx | Esophagus Mucosa | 1 | 0.031 | 1.5 |
GTEx | Esophagus Muscularis | 1 | 0.031 | 1.5 |
GTEx | Heart Atrial Appendage | 2 | 0.128 | 1.5 |
GTEx | Heart Left Ventricle | 1 | 0.067 | 1.5 |
GTEx | Lung | 4 | 0.142 | 1.5 |
GTEx | Nerve Tibial | 1 | 0.024 | 1.5 |
GTEx | Ovary | 1 | 0.112 | 1.5 |
GTEx | Pancreas | 4 | 0.248 | 1.5 |
GTEx | Pituitary | 2 | 0.181 | 1.5 |
GTEx | Skin Not Sun Exposed Suprapubic | 0 | 0.000 | 1.5 |
GTEx | Skin Sun Exposed Lower leg | 5 | 0.140 | 1.5 |
GTEx | Spleen | 3 | 0.216 | 1.5 |
GTEx | Stomach | 1 | 0.069 | 1.5 |
GTEx | Testis | 2 | 0.064 | 1.5 |
GTEx | Vagina | 0 | 0.000 | 1.5 |
GTEx | Whole Blood | 6 | 0.306 | 1.5 |
NTR | Blood | 6 | 0.251 | 1.5 |
YFS | Blood | 6 | 0.130 | 1.5 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 1 | 0.062 | 1.5 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 2 | 0.187 | 1.5 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 2 | 0.100 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 3 | 0.150 | 1.5 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 2 | 0.070 | 1.5 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 4 | 0.164 | 1.5 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 3 | 0.186 | 1.5 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 2 | 0.295 | 1.5 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.5 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 5 | 0.305 | 1.5 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 3 | 0.241 | 1.5 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 1 | 0.204 | 1.5 |
GTEx | Artery Tibial | 2 | 0.054 | 1.4 |
GTEx | Brain Cerebellar Hemisphere | 1 | 0.068 | 1.4 |
GTEx | Brain Cerebellum | 1 | 0.051 | 1.4 |
GTEx | Breast Mammary Tissue | 1 | 0.051 | 1.4 |
GTEx | Breast Mammary Tissue (Female) | 1 | 0.062 | 1.4 |
GTEx | Muscle Skeletal | 2 | 0.070 | 1.4 |
GTEx | Prostate | 0 | 0.000 | 1.4 |
GTEx | Thyroid | 1 | 0.025 | 1.4 |
METSIM | Adipose | 3 | 0.066 | 1.4 |
CommonMind | Brain Pre-frontal Cortex | 7 | 0.131 | 1.4 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 3 | 0.070 | 1.4 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 3 | 0.113 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 3 | 0.075 | 1.4 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 3 | 0.072 | 1.4 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 1 | 0.064 | 1.4 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 3 | 0.067 | 1.4 |
The Cancer Genome Atlas | Thyroid Carcinoma | 5 | 0.100 | 1.4 |
ROSMAP | Brain Pre-frontal Cortex | 3 | 0.069 | 1.3 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.3 |