[Hub]/) : Traits : Primary Biliary Cirrhosis : ← →

chr16:10,329,905-12,138,068

Best TWAS P=6.61e-14 · Best GWAS P=2.38e-14 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RMI2	0.49	0.43	bslmm	534	0.57	4.4e-84	-5.8	-5.4	7.4e-08	0.17	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	RMI2	0.10	0.06	lasso	5	0.07	1.9e-06	-5.1	-5.2	1.7e-07	-0.06	0.95	0.00	FALSE
3	GTEx	Adrenal Gland	RMI2	0.24	0.12	lasso	7	0.15	5.2e-06	-5.8	-5.1	2.9e-07	0.14	0.63	0.21	FALSE
4	GTEx	Artery Aorta	RMI2	0.30	0.11	lasso	5	0.17	1.3e-09	-5.1	-6.0	2.2e-09	0.05	0.99	0.00	FALSE
5	GTEx	Artery Coronary	RMI2	0.32	0.14	lasso	6	0.12	9.9e-05	-5.0	-5.3	9.2e-08	-0.02	0.76	0.06	FALSE
6	GTEx	Artery Tibial	RMI2	0.27	0.11	enet	27	0.21	1.4e-16	-5.0	-5.7	1.4e-08	0.05	1.00	0.00	FALSE
7	GTEx	Brain Caudate basal ganglia	RMI2	0.46	0.22	enet	19	0.24	1.2e-07	-5.8	-6.3	2.9e-10	0.13	0.78	0.04	FALSE
8	GTEx	Brain Cortex	RMI2	0.55	0.15	enet	10	0.17	2.3e-05	-5.8	-5.6	1.8e-08	0.14	0.73	0.03	FALSE
9	GTEx	Brain Putamen basal ganglia	RMI2	0.48	0.31	lasso	9	0.40	1.7e-10	-5.8	-5.8	7.2e-09	0.29	0.69	0.03	FALSE
10	GTEx	Breast Mammary Tissue	RMI2	0.37	0.25	lasso	7	0.21	3.5e-11	-5.8	-5.7	1.5e-08	0.12	1.00	0.00	FALSE
11	GTEx	Breast Mammary Tissue (Male)	RMI2	0.32	0.15	enet	25	0.10	2.9e-03	-5.8	-5.4	7.4e-08	0.30	0.07	0.13	FALSE
12	GTEx	Breast Mammary Tissue (Male)	DEXI	0.18	0.04	lasso	3	-0.01	4.9e-01	-7.3	-7.5	6.6e-14	0.96	0.02	0.73	TRUE
13	GTEx	Cells EBV-transformed lymphocytes	RMI2	0.50	0.06	enet	11	0.35	4.3e-12	-3.3	5.5	3.6e-08	-0.14	0.58	0.31	FALSE
14	GTEx	Cells Transformed fibroblasts	DEXI	0.12	0.05	lasso	5	0.08	9.6e-07	-6.6	-5.6	2.4e-08	0.82	0.02	0.98	FALSE
15	GTEx	Cells Transformed fibroblasts	RP11-876N24.4	0.12	0.04	lasso	5	0.08	2.1e-06	-6.6	-5.6	1.8e-08	0.83	0.02	0.98	FALSE
16	GTEx	Colon Sigmoid	RMI2	0.30	0.09	enet	11	0.12	6.2e-05	-5.8	-6.1	8.5e-10	0.19	0.74	0.08	FALSE
17	GTEx	Heart Atrial Appendage	RMI2	0.33	0.13	lasso	8	0.10	4.0e-05	-5.7	-6.5	8.6e-11	0.22	0.38	0.12	FALSE
18	GTEx	Heart Left Ventricle	RMI2	0.24	0.09	lasso	6	0.12	6.2e-07	-5.1	-5.7	9.4e-09	0.01	0.86	0.01	FALSE
19	GTEx	Muscle Skeletal	RMI2	0.28	0.12	lasso	11	0.20	2.1e-19	-5.1	-6.4	1.9e-10	0.00	0.95	0.05	TRUE
20	GTEx	Ovary	RMI2	0.48	0.26	lasso	9	0.20	1.2e-05	-5.8	-6.2	6.5e-10	0.15	0.32	0.09	FALSE
21	GTEx	Pancreas	DEXI	0.13	0.06	lasso	4	0.07	5.7e-04	-5.1	-5.5	4.4e-08	0.82	0.06	0.89	FALSE
22	GTEx	Pancreas	RP11-876N24.4	0.11	0.05	lasso	3	0.04	8.6e-03	-5.1	-5.6	2.7e-08	0.83	0.06	0.88	FALSE
23	GTEx	Pituitary	RMI2	0.52	0.18	enet	6	0.32	6.6e-09	-5.8	-5.8	5.1e-09	0.14	0.42	0.05	FALSE
24	GTEx	Thyroid	RMI2	0.44	0.31	enet	37	0.40	2.2e-32	-5.8	-5.3	9.1e-08	0.16	1.00	0.00	FALSE
25	METSIM	Adipose	RMI2	0.20	0.18	lasso	8	0.26	3.0e-38	-5.8	-5.2	2.1e-07	0.15	1.00	0.00	FALSE
26	NTR	Blood	C16orf75	0.03	0.01	enet	10	0.02	6.4e-08	-5.1	-5.7	9.3e-09	0.06	0.85	0.08	FALSE
27	ROSMAP	Brain Pre-frontal Cortex	RMI2	0.46	0.49	bslmm	510	0.58	1.5e-92	-5.8	-5.4	5.3e-08	0.16	1.00	0.00	FALSE
28	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C16orf75	0.32	0.14	enet	10	0.27	8.2e-14	-3.3	5.9	2.9e-09	-0.15	0.02	0.98	FALSE
29	The Cancer Genome Atlas	Glioblastoma Multiforme	C16orf75	0.12	0.02	blup	112	0.04	1.9e-02	-5.8	5.3	8.9e-08	-0.10	0.02	0.60	FALSE
30	The Cancer Genome Atlas	Skin Cutaneous Melanoma	DEXI	0.20	0.00	blup	49	0.06	1.3e-02	5.5	-5.3	1.2e-07	0.54	0.01	0.33	FALSE
31	The Cancer Genome Atlas	Stomach Adenocarcinoma	C16orf75	0.21	0.10	lasso	6	0.18	9.8e-13	-5.2	5.5	2.9e-08	-0.05	0.12	0.88	FALSE
32	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C16orf75	0.27	0.14	lasso	4	0.20	1.4e-07	-5.2	5.5	4.2e-08	-0.01	0.24	0.68	FALSE