[Hub]/) : Traits : Prostate Cancer :

chr11:68,227,852-69,623,641

Best TWAS P=4.77e-38 · Best GWAS P=2.55e-45 conditioned to 1.02e-11

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-554A11.9 0.34 0.13 enet 43 0.26 4.1e-21 4.167 6.5 7.8e-11 0.15 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum RP11-554A11.9 0.28 0.01 enet 27 0.13 4.3e-07 4.167 6.3 3.2e-10 0.22 0.36 0.03 FALSE
3 GTEx Brain Cerebellar Hemisphere RP11-554A11.9 0.49 0.17 lasso 9 0.20 8.5e-06 10.835 9.6 7.1e-22 0.30 0.53 0.04 TRUE
4 GTEx Brain Cerebellum RP11-554A11.9 0.59 0.16 enet 29 0.33 1.4e-10 9.653 5.3 1.2e-07 0.04 0.40 0.03 TRUE
5 GTEx Breast Mammary Tissue RP11-554A11.9 0.32 0.11 lasso 7 0.26 9.4e-14 4.167 7.7 1.4e-14 0.21 0.73 0.09 FALSE
6 GTEx Breast Mammary Tissue (Male) RP11-554A11.9 0.23 0.08 lasso 4 0.08 6.7e-03 10.241 12.9 4.8e-38 0.47 0.04 0.38 TRUE
7 GTEx Breast Mammary Tissue (Female) RP11-554A11.9 0.40 0.25 enet 18 0.30 1.5e-09 4.167 5.5 5.0e-08 0.18 0.58 0.02 FALSE
8 GTEx Colon Sigmoid RP11-554A11.9 0.65 0.29 enet 36 0.41 8.3e-16 4.167 7.7 1.7e-14 0.26 0.99 0.00 FALSE
9 GTEx Colon Transverse RP11-554A11.9 0.26 0.11 lasso 9 0.10 2.5e-05 9.653 9.6 1.1e-21 0.27 0.28 0.04 FALSE
10 GTEx Esophagus Muscularis RP11-554A11.9 0.31 0.18 lasso 9 0.22 1.4e-13 4.167 6.9 3.7e-12 0.13 1.00 0.00 FALSE
11 GTEx Heart Atrial Appendage RP11-554A11.9 0.24 0.05 lasso 8 0.09 9.5e-05 2.724 8.0 1.5e-15 0.04 0.15 0.04 FALSE
12 GTEx Heart Left Ventricle RP11-554A11.9 0.16 0.11 lasso 3 0.09 2.2e-05 4.167 7.1 1.4e-12 0.22 0.39 0.03 FALSE
13 GTEx Lung RP11-554A11.9 0.28 0.10 enet 34 0.20 1.6e-15 4.167 9.5 2.2e-21 0.28 1.00 0.00 TRUE
14 GTEx Nerve Tibial RP11-554A11.9 0.43 0.10 lasso 11 0.33 8.7e-24 4.167 6.9 6.4e-12 0.18 1.00 0.00 FALSE
15 GTEx Prostate RP11-554A11.9 0.44 0.11 enet 13 0.18 2.8e-05 7.911 9.6 8.8e-22 0.29 0.17 0.05 FALSE
16 GTEx Skin Not Sun Exposed Suprapubic RP11-554A11.9 0.28 0.13 lasso 9 0.21 1.5e-11 0.054 6.4 1.3e-10 0.17 0.83 0.01 FALSE
17 GTEx Thyroid RP11-554A11.9 0.40 0.14 lasso 7 0.25 8.1e-19 4.167 6.8 8.2e-12 0.15 1.00 0.00 FALSE
18 GTEx Vagina RP11-554A11.9 0.49 0.11 lasso 6 0.12 9.5e-04 10.835 9.1 7.2e-20 0.25 0.09 0.06 FALSE