Best TWAS P=9.21e-12 · Best GWAS P=7.24e-29 conditioned to 1.18e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ASCL2 | 0.02 | 0.02 | lasso | 2 | 0.02 | 0.00021 | 6.8 | 6.8 | 9.2e-12 | 0.54 | 0.00 | 1.00 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TH | 0.02 | 0.01 | enet | 11 | 0.01 | 0.00098 | 3.7 | 5.8 | 5.7e-09 | 0.55 | 0.11 | 0.33 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | TH | 0.05 | 0.03 | blup | 60 | 0.01 | 0.01940 | 3.7 | -6.5 | 1.1e-10 | -0.62 | 0.05 | 0.08 | TRUE |