TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Prostate Cancer
:
←
→
chr11:1,938,523-2,541,165
Best TWAS P=9.21e-12 · Best GWAS P=7.24e-29 conditioned to 1.18e-14
2M
2.1M
2.2M
2.3M
2.4M
2.5M
0
5
10
15
20
25
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
ASCL2
0.02
0.02
lasso
2
0.02
0.00021
6.8
6.8
9.2e-12
0.54
0.00
1.00
TRUE
3
The Cancer Genome Atlas
Thyroid Carcinoma
TH
0.05
0.03
blup
60
0.01
0.01940
3.7
-6.5
1.1e-10
-0.62
0.05
0.08
TRUE
2
The Cancer Genome Atlas
Breast Invasive Carcinoma
TH
0.02
0.01
enet
11
0.01
0.00098
3.7
5.8
5.7e-09
0.55
0.11
0.33
FALSE