Hub : Traits :

Prostate Cancer

327 significantly associated models · 91 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	24404988	24929676	1	1	2.1e-08	2.0e-05	3.0e-01	94	GRHL3
2	1	150527354	151021509	1	1	1.5e-08	5.4e-09	1.3e-01	93	CTSK
3	1	153220716	155699118	8	2	3.4e-09	3.8e-08	3.7e-02	86	CRTC2 DCST2
4	1	203692179	206329620	3	2	4.8e-13	2.3e-13	1.0e+00	100	MDM4 NUCKS1
5	2	10016627	11619674	2	1	2.7e-11	8.1e-12	8.6e-03	85	NOL10
6	2	20189015	21719583	1	1	1.1e-08	1.6e-10	1.6e-03	76	C2orf43
7	2	62211083	64747556	3	6	1.2e-17	5.0e-20	NaN	NaN	AC007098.1 EHBP1 WDPCP
8	2	84884961	86518249	6	1	2.5e-12	9.2e-11	8.3e-01	100	GGCX
9	3	86583852	87999964	1	1	8.7e-16	8.5e-21	5.3e-07	71	CHMP2B
10	3	112317291	114043692	3	1	7.2e-12	3.8e-09	5.9e-01	99	WDR52
11	3	127074386	128821807	3	1	8.7e-15	6.9e-14	6.8e-01	100	EEFSEC
12	3	169058009	170717996	4	4	8.1e-13	1.7e-11	1.0e+00	100	GPR160 PHC3 PRKCI SKIL
13	4	94674019	96286793	1	1	1.1e-09	1.8e-09	8.1e-02	92	PDLIM5
14	5	1635899	2131784	1	1	3.2e-12	1.4e-12	1.0e+00	100	IRX4
15	7	26010759	28573565	3	3	7.1e-17	1.3e-22	2.7e-07	72	SKAP2 TAX1BP1
16	7	97038925	98725348	7	2	2.6e-15	3.7e-18	1.2e-01	97	BHLHA15 LMTK2
17	8	22842752	24224911	1	2	6.4e-11	4.8e-28	7.1e-17	42	NKX3-1
18	9	18355044	19797850	2	1	4.1e-09	6.7e-10	5.4e-02	90	HAUS6
19	10	50336129	52456629	6	2	7.2e-68	6.1e-59	3.0e-03	97	AGAP6 NCOA4
20	10	103718818	105108455	1	1	1.7e-07	4.9e-06	6.4e-01	99	TRIM8
21	11	1938523	2541165	2	2	9.2e-12	7.2e-29	1.2e-14	52	ASCL2 TH
22	11	68227852	69623641	1	4	4.8e-38	2.5e-45	1.0e-11	77	RP11-554A11.9
23	11	75457950	76959598	1	1	3.0e-07	2.7e-08	1.0e+00	100	C11orf30
24	17	3587	1381005	5	1	3.2e-13	3.2e-12	1.0e+00	100	GEMIN4
25	17	35034943	36441093	2	4	2.2e-44	1.7e-73	1.7e-30	60	C17orf78 HNF1B
26	19	38052193	39476803	2	1	2.1e-21	4.9e-20	9.6e-03	92	PPP1R14A
27	19	41260831	42741124	3	1	2.0e-12	6.3e-12	1.0e+00	100	AC011526.1
28	20	61576647	62912463	6	2	6.6e-12	1.6e-11	1.0e+00	100	LIME1 STMN3
29	21	42591611	43141441	1	1	4.6e-08	2.4e-11	6.9e-05	64	TMPRSS2
30	22	42835727	44282307	5	1	5.0e-34	3.2e-43	8.4e-30	32	BIK

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Allergy or Eczema	3.04	8	4	8.9	0.72	0.028	AGAP6 C11orf30 DCST2 LIME1 NCOA4 STMN3 TRIM8 WDPCP
Allergy	2.78	7	2	4.4	-0.38	0.347	C11orf30 CRTC2 EEFSEC LIME1 STMN3 TRIM8 WDPCP
Hayfever, allergic rhinitis or eczema	2.66	6	2	4.4	0.71	0.111	C11orf30 DCST2 LIME1 NCOA4 STMN3 TRIM8
Respiratory disease	1.93	3	1	2.2	-0.32	0.594	C11orf30 EEFSEC WDPCP
Medication: Metformin	1.81	1	0	0.0	0.00	1.000	HAUS6
Birth weight	1.78	3	1	2.2	0.00	1.000	ASCL2 DCST2 NUCKS1
Crohns Disease (2017)	1.75	3	2	4.4	0.00	1.000	C11orf30 LIME1 STMN3
Hayfever/allergic rhinitis (self-reported)	1.73	1	0	0.0	0.00	1.000	C11orf30
Irritable Bowel Disease (IBD)	1.70	3	3	6.7	0.00	1.000	C11orf30 LIME1 STMN3
Hair Pigment	1.69	5	4	8.9	0.52	0.099	DCST2 GRHL3 NUCKS1 RP11-554A11.9 WDPCP
Vitamin and mineral supplements	1.67	1	0	0.0	0.00	1.000	NUCKS1
Illnesses of father: Heart disease	1.66	2	0	0.0	0.00	1.000	AC007098.1 GGCX
Crohns Disease (2012)	1.65	1	0	0.0	0.00	1.000	STMN3
Smoking Status	1.65	3	1	2.2	0.00	1.000	LMTK2 TRIM8 WDPCP
Heart disease (siblings)	1.65	1	0	0.0	0.00	1.000	AC007098.1
Lung FVC	1.64	8	3	6.7	-0.48	0.160	AC007098.1 EHBP1 LIME1 MDM4 NUCKS1 STMN3 TAX1BP1 WDPCP
Lung cancer (father)	1.63	1	0	0.0	0.00	1.000	MDM4
Systolic Blood Pressure	1.61	6	3	6.7	-0.13	0.737	C11orf30 C2orf43 CTSK LIME1 SKAP2 WDPCP
Current tobacco smoking	1.56	1	0	0.0	0.00	1.000	BHLHA15
Diabetes diagnosed by doctor	1.56	1	0	0.0	0.00	1.000	HNF1B
Asthma (self-reported)	1.56	1	0	0.0	0.00	1.000	EEFSEC
Hand grip strength (left)	1.54	4	1	2.2	-0.38	0.617	ASCL2 NUCKS1 TAX1BP1 TRIM8
Medication: Blood pressure	1.54	1	0	0.0	0.00	1.000	CTSK
Ulcerative Colitis	1.53	2	0	0.0	0.00	1.000	LIME1 STMN3
Illnesses of father: None of the above (group 1)	1.53	1	0	0.0	0.00	1.000	NUCKS1
Type 2 Diabetes (T2D) (2018)	1.52	1	0	0.0	0.00	1.000	HNF1B
Asthma	1.52	1	0	0.0	0.00	1.000	EEFSEC
Breast Cancer	1.50	2	1	2.2	0.46	0.543	BIK RP11-554A11.9
High blood pressure	1.50	4	0	0.0	0.60	0.403	CRTC2 CTSK MDM4 SKAP2
Lung FEV1/FVC ratio	1.49	5	2	4.4	0.65	0.231	BIK DCST2 EEFSEC HNF1B NUCKS1
Arm predicted mass (right)	1.47	7	2	4.4	-0.44	0.279	ASCL2 DCST2 EHBP1 GGCX NUCKS1 TRIM8 WDPCP
Impedance of leg (left)	1.44	5	2	4.4	0.41	0.489	ASCL2 DCST2 HAUS6 NOL10 NUCKS1
Past tobacco smoking	1.44	1	1	2.2	0.00	1.000	TRIM8
Heart attack	1.43	1	0	0.0	0.00	1.000	AC007098.1
Arm fat-free mass (right)	1.43	7	3	6.7	-0.44	0.273	ASCL2 DCST2 EHBP1 GGCX NUCKS1 TRIM8 WDPCP
Arm predicted mass (left)	1.43	6	3	6.7	-0.34	0.457	DCST2 EHBP1 GGCX NUCKS1 TRIM8 WDPCP
Relative age of first facial hair	1.42	1	0	0.0	0.00	1.000	MDM4
Hand grip strength (right)	1.42	2	1	2.2	0.00	1.000	NUCKS1 TAX1BP1
Arm fat-free mass (left)	1.42	7	2	4.4	-0.43	0.289	ASCL2 DCST2 EHBP1 GGCX NUCKS1 TRIM8 WDPCP
Ever smoked	1.40	1	0	0.0	0.00	1.000	TRIM8
Impedance of leg (right)	1.39	6	1	2.2	-0.11	0.835	AC007098.1 ASCL2 DCST2 HAUS6 NOL10 NUCKS1
Hearing difficulty/problems with background noise	1.39	2	1	2.2	0.00	1.000	NUCKS1 TRIM8
Peak expiratory flow (PEF)	1.39	2	1	2.2	0.00	1.000	MDM4 NUCKS1
Basal metabolic rate	1.36	7	3	6.7	-0.47	0.244	ASCL2 DCST2 EHBP1 GGCX NUCKS1 TRIM8 WDPCP
Vascular/heart problems diagnosed by doctor	1.36	4	0	0.0	-0.57	0.432	CRTC2 CTSK MDM4 SKAP2
Leg fat-free mass (right)	1.34	7	2	4.4	0.43	0.336	AGAP6 ASCL2 DCST2 GGCX NUCKS1 TRIM8 WDPCP
Whole body water mass	1.34	6	3	6.7	-0.40	0.371	ASCL2 DCST2 GGCX NUCKS1 TRIM8 WDPCP
Leg fat-free mass (left)	1.33	5	2	4.4	-0.45	0.376	ASCL2 DCST2 GGCX NUCKS1 WDPCP
Hypertension (Self-reported)	1.33	2	0	0.0	0.00	1.000	MDM4 SKAP2
Whole body fat-free mass	1.33	6	3	6.7	-0.39	0.393	ASCL2 DCST2 GGCX NUCKS1 TRIM8 WDPCP
Leg predicted mass (right)	1.33	7	2	4.4	0.43	0.334	AGAP6 ASCL2 DCST2 GGCX NUCKS1 TRIM8 WDPCP
Impedance of whole body	1.33	7	1	2.2	0.44	0.327	ASCL2 DCST2 EEFSEC HNF1B NOL10 NUCKS1 TAX1BP1
Reaction Time	1.32	1	0	0.0	0.00	1.000	RP11-554A11.9
Leg predicted mass (left)	1.32	5	2	4.4	-0.45	0.373	ASCL2 DCST2 GGCX NUCKS1 WDPCP
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.32	1	0	0.0	0.00	1.000	STMN3
Diastolic blood pressure, automated reading	1.31	5	0	0.0	0.71	0.175	C11orf30 LIME1 MDM4 SKAP2 STMN3
Multivitamins +/- minerals	1.30	1	0	0.0	0.00	1.000	NUCKS1
Weight	1.30	7	2	4.4	0.38	0.347	AC007098.1 DCST2 EHBP1 GGCX NUCKS1 TRIM8 WDPCP
Worrier / anxious feelings	1.30	1	0	0.0	0.00	1.000	TRIM8
Trunk fat-free mass	1.29	6	3	6.7	-0.52	0.234	ASCL2 DCST2 GGCX NUCKS1 TRIM8 WDPCP
Trunk predicted mass	1.29	6	3	6.7	-0.50	0.251	ASCL2 DCST2 GGCX NUCKS1 TRIM8 WDPCP
High cholesterol (Self-reported)	1.29	1	0	0.0	0.00	1.000	AC007098.1
Age when periods started (menarche)	1.28	4	1	2.2	-0.37	0.631	C11orf30 CRTC2 EEFSEC NUCKS1
Hip circumference	1.27	4	2	4.4	-0.46	0.440	DCST2 EHBP1 GGCX WDPCP
Tense / 'highly strung'	1.27	1	0	0.0	0.00	1.000	NUCKS1
Blood Platelet Count	1.26	13	11	24.4	0.24	0.386	BIK C11orf30 C17orf78 CRTC2 DCST2 EEFSEC HAUS6 LIME1 PPP1R14A RP11-554A11.9 STMN3 TRIM8 WDR52
Cardiovascular Disease	1.26	1	0	0.0	0.00	1.000	CRTC2
Impedance of arm (right)	1.25	6	2	4.4	0.58	0.174	ASCL2 DCST2 EEFSEC NUCKS1 TAX1BP1 WDPCP
Gout (self-reported)	1.25	1	0	0.0	0.00	1.000	DCST2
Waist circumference	1.23	2	1	2.2	0.07	0.934	EHBP1 WDPCP
Noisy workplace	1.22	1	0	0.0	0.00	1.000	CRTC2
Diverticular disease/diverticulitis (self-reported)	1.20	1	0	0.0	0.00	1.000	PPP1R14A
Medication: Allopurinol	1.20	1	0	0.0	0.00	1.000	DCST2
Pulse rate, automated reading	1.20	4	0	0.0	-0.45	0.549	C11orf30 CTSK PDLIM5 PPP1R14A
Angina	1.19	1	0	0.0	0.00	1.000	GGCX
Impedance of arm (left)	1.19	4	2	4.4	0.70	0.300	ASCL2 DCST2 EEFSEC TAX1BP1
Angina (self-reported)	1.17	1	0	0.0	0.00	1.000	GGCX
Body mass index (BMI)	1.14	4	0	0.0	0.62	0.268	AC007098.1 DCST2 EHBP1 WDPCP
Ulcerative Colitis (UC)	1.12	2	0	0.0	0.00	1.000	C11orf30 STMN3
Mean time to correctly identify matches	1.12	2	0	0.0	0.00	1.000	NUCKS1 RP11-554A11.9
Arm fat mass (left)	1.12	3	0	0.0	-0.38	0.616	DCST2 EHBP1 WDPCP
Illnesses of father: High blood pressure	1.11	1	0	0.0	0.00	1.000	MDM4
Nervous feelings	1.09	2	0	0.0	0.00	1.000	BHLHA15 LMTK2
Arm fat mass (right)	1.08	3	0	0.0	0.50	0.504	DCST2 EHBP1 WDPCP
Number of treatments/medications taken	1.07	1	0	0.0	0.00	1.000	NUCKS1
Heel bone mineral density (BMD) T-score, automated (right)	1.07	1	0	0.0	0.00	1.000	TAX1BP1
Forced expiratory volume in 1-second (FEV1)	1.07	2	0	0.0	0.00	1.000	LIME1 MDM4
Whole body fat mass	1.06	2	0	0.0	0.00	1.000	EHBP1 WDPCP
Comparative height size at age 10	1.06	5	2	4.4	0.44	0.453	DCST2 GGCX HAUS6 NUCKS1 TRIM8
Leg fat mass (left)	1.06	2	0	0.0	0.00	1.000	EHBP1 WDPCP
Worry (Nagel 2018)	1.05	2	0	0.0	0.00	1.000	BHLHA15 LMTK2
Waist Hip Ratio (WHR)	1.04	6	2	4.4	0.02	0.965	CTSK DCST2 RP11-554A11.9 SKAP2 TRIM8 WDR52
Leg fat mass (right)	1.03	2	0	0.0	0.00	1.000	EHBP1 WDPCP
Forced expiratory volume in 1-second (FEV1), predicted	1.03	1	1	2.2	0.00	1.000	TRIM8
Neuroticism (Nagel 2018)	1.02	2	0	0.0	0.00	1.000	BHLHA15 LMTK2
Forced vital capacity (FVC)	1.02	4	1	2.2	-0.40	0.596	LIME1 MDM4 STMN3 TRIM8
Neuroticism score	1.01	1	0	0.0	0.00	1.000	NUCKS1
BMI	1.00	4	2	4.4	-0.88	0.048	ASCL2 DCST2 EHBP1 WDPCP
Forced expiratory volume in 1-second (FEV1), Best measure	1.00	1	0	0.0	0.00	1.000	MDM4
Hair/balding pattern: Pattern 4	1.00	2	2	4.4	0.00	1.000	CRTC2 GRHL3
Comparative body size at age 10	0.99	1	1	2.2	0.00	1.000	NUCKS1
Trunk fat mass	0.97	3	0	0.0	0.40	0.499	EHBP1 GGCX WDPCP
Fluid intelligence score	0.97	1	0	0.0	0.00	1.000	CRTC2
Systolic blood pressure, automated reading	0.94	2	0	0.0	0.00	1.000	LIME1 SKAP2
Coronary Artery Disease (CAD)	0.93	1	0	0.0	0.00	1.000	GGCX
Tanning	0.93	5	3	6.7	-0.04	0.926	DCST2 EHBP1 LMTK2 RP11-554A11.9 WDPCP
Forced vital capacity (FVC), Best measure	0.93	3	1	2.2	0.00	1.000	MDM4 STMN3 TRIM8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.93	1	0	0.0	0.00	1.000	NUCKS1
Heel T-Score	0.92	5	3	6.7	-0.92	0.001	GPR160 PDLIM5 PHC3 RP11-554A11.9 TAX1BP1
Blood Eosinophil Count	0.91	8	4	8.9	0.22	0.594	C11orf30 DCST2 GEMIN4 GGCX GPR160 MDM4 NKX3-1 PHC3
Sitting height	0.90	3	2	4.4	0.00	1.000	DCST2 NUCKS1 TRIM8
Arm fat percentage (right)	0.90	1	0	0.0	0.00	1.000	TAX1BP1
Bipolar Disorder or Schizophrenia	0.89	2	0	0.0	0.00	1.000	DCST2 EEFSEC
Height	0.88	12	6	13.3	0.08	0.811	C11orf30 DCST2 GGCX HAUS6 LIME1 MDM4 NKX3-1 NUCKS1 SKAP2 TH TRIM8 WDR52
Mood swings	0.87	1	0	0.0	0.00	1.000	NUCKS1
Heel bone mineral density (BMD) T-score, automated (left)	0.86	1	0	0.0	0.00	1.000	TAX1BP1
High blood pressure (mother)	0.86	1	0	0.0	0.00	1.000	MDM4
Body fat percentage	0.86	1	0	0.0	0.00	1.000	EHBP1
Age at First Birth	0.85	1	1	2.2	0.00	1.000	CRTC2
Trunk fat percentage	0.85	1	0	0.0	0.00	1.000	TAX1BP1
Verbal and Numeric Reasoning (VNR)	0.84	2	0	0.0	0.00	1.000	AC007098.1 CRTC2
Medication: Omeprazole (e.g. Zanprol)	0.84	1	0	0.0	0.00	1.000	C2orf43
Standing height	0.80	4	3	6.7	0.12	0.876	DCST2 GGCX NUCKS1 TRIM8
Intelligence (Savage-Jansen 2018)	0.75	2	0	0.0	0.00	1.000	AC007098.1 CRTC2
Blood White Count	0.71	6	2	4.4	0.29	0.573	C11orf30 C17orf78 GGCX STMN3 TH TRIM8
Hypothyroidism (self reported)	0.70	1	0	0.0	0.00	1.000	DCST2
Chronotype (morning person)	0.64	1	0	0.0	0.00	1.000	CTSK
Blood Red Count	0.50	4	2	4.4	0.53	0.467	C17orf78 LIME1 NKX3-1 STMN3

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Prostate	4	0.529	2.0
The Cancer Genome Atlas	Prostate Adenocarcinoma	17	0.418	1.8
GTEx	Adipose Subcutaneous	9	0.288	1.7
GTEx	Brain Cerebellar Hemisphere	4	0.301	1.7
GTEx	Brain Frontal Cortex BA9	3	0.358	1.7
GTEx	Brain Nucleus accumbens basal ganglia	2	0.254	1.7
GTEx	Brain Putamen basal ganglia	1	0.178	1.7
GTEx	Breast Mammary Tissue	7	0.393	1.7
GTEx	Breast Mammary Tissue (Male)	4	0.372	1.7
GTEx	Breast Mammary Tissue (Female)	6	0.405	1.7
GTEx	Colon Transverse	7	0.378	1.7
GTEx	Esophagus Mucosa	10	0.337	1.7
GTEx	Esophagus Muscularis	9	0.314	1.7
GTEx	Nerve Tibial	14	0.362	1.7
GTEx	Spleen	3	0.235	1.7
NTR	Blood	8	0.380	1.7
YFS	Blood	12	0.297	1.7
The Cancer Genome Atlas	Esophageal Carcinoma	1	0.169	1.7
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	3	0.167	1.7
GTEx	Adipose Visceral Omentum	6	0.325	1.6
GTEx	Artery Tibial	8	0.240	1.6
GTEx	Brain Cerebellum	6	0.334	1.6
GTEx	Brain Cortex	3	0.319	1.6
GTEx	Brain Hippocampus	0	0.000	1.6
GTEx	Brain Hypothalamus	1	0.185	1.6
GTEx	Cells EBV-transformed lymphocytes	4	0.316	1.6
GTEx	Cells Transformed fibroblasts	10	0.269	1.6
GTEx	Colon Sigmoid	5	0.381	1.6
GTEx	Heart Atrial Appendage	2	0.141	1.6
GTEx	Heart Left Ventricle	4	0.292	1.6
GTEx	Liver	1	0.156	1.6
GTEx	Lung	5	0.195	1.6
GTEx	Pancreas	2	0.137	1.6
GTEx	Pituitary	0	0.000	1.6
GTEx	Skin Not Sun Exposed Suprapubic	7	0.318	1.6
GTEx	Skin Sun Exposed Lower leg	11	0.338	1.6
GTEx	Small Intestine Terminal Ileum	1	0.245	1.6
GTEx	Stomach	3	0.231	1.6
GTEx	Testis	9	0.320	1.6
GTEx	Thyroid	10	0.281	1.6
GTEx	Vagina	2	0.345	1.6
GTEx	Whole Blood	4	0.225	1.6
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	4	0.279	1.6
The Cancer Genome Atlas	Breast Invasive Carcinoma	12	0.308	1.6
The Cancer Genome Atlas	Glioblastoma Multiforme	2	0.219	1.6
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	2	0.207	1.6
The Cancer Genome Atlas	Lung Adenocarcinoma	8	0.309	1.6
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	0	0.000	1.6
The Cancer Genome Atlas	Thyroid Carcinoma	12	0.263	1.6
GTEx	Adrenal Gland	2	0.154	1.5
GTEx	Artery Aorta	5	0.188	1.5
GTEx	Artery Coronary	2	0.187	1.5
GTEx	Brain Caudate basal ganglia	0	0.000	1.5
GTEx	Esophagus Gastroesophageal Junction	2	0.153	1.5
GTEx	Muscle Skeletal	6	0.233	1.5
GTEx	Ovary	1	0.121	1.5
GTEx	Uterus	1	0.195	1.5
METSIM	Adipose	6	0.149	1.5
ROSMAP	Brain Pre-frontal Cortex	6	0.150	1.5
CommonMind	Brain Pre-frontal Cortex	11	0.232	1.5
The Cancer Genome Atlas	Colon Adenocarcinoma	0	0.000	1.5
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	2	0.084	1.5
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	3	0.083	1.5
The Cancer Genome Atlas	Brain Lower Grade Glioma	6	0.158	1.5
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	2	0.145	1.5
The Cancer Genome Atlas	Stomach Adenocarcinoma	1	0.069	1.5
The Cancer Genome Atlas	Testicular Germ Cell Tumors	1	0.089	1.5
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	0	0.000	1.4
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	1	0.046	1.4
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	0	0.000	1.4
The Cancer Genome Atlas	Rectum Adenocarcinoma	0	0.000	1.4
The Cancer Genome Atlas	Skin Cutaneous Melanoma	1	0.213	1.4
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	0	0.000	1.4
The Cancer Genome Atlas	Soft Tissue Sarcoma	0	0.000	1.3