[Hub]/) : Traits : Blood Red Count :

chr1:37,222,762-39,167,106

Best TWAS P=7.62e-11 · Best GWAS P=7.52e-10 conditioned to 0.144

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial MEAF6 0.25 0.13 lasso 7 0.17 2.4e-13 -5.8 -5.3 1.4e-07 -0.10 0.02 0.98 FALSE
2 GTEx Breast Mammary Tissue RP11-109P14.9 0.19 0.00 lasso 4 0.01 1.4e-01 -6.0 -6.0 2.5e-09 -0.32 0.04 0.23 FALSE
3 GTEx Breast Mammary Tissue (Male) RP11-422J8.1 0.09 0.04 lasso 3 0.06 1.7e-02 -4.8 5.5 2.9e-08 0.24 0.05 0.14 FALSE
4 GTEx Cells EBV-transformed lymphocytes GNL2 0.25 0.10 lasso 4 0.07 2.3e-03 -5.8 -6.5 7.6e-11 -0.08 0.02 0.96 TRUE
5 GTEx Cells EBV-transformed lymphocytes MEAF6 0.36 0.10 lasso 5 0.23 5.6e-08 -5.8 -6.0 2.6e-09 -0.09 0.02 0.97 FALSE
6 GTEx Cells Transformed fibroblasts GNL2 0.24 0.19 lasso 6 0.18 7.6e-14 -5.7 -5.7 1.6e-08 -0.11 0.02 0.98 FALSE
7 GTEx Esophagus Mucosa MEAF6 0.12 0.10 enet 7 0.09 2.1e-06 -5.8 -5.5 3.6e-08 -0.09 0.02 0.98 FALSE
8 GTEx Esophagus Muscularis MEAF6 0.13 0.02 lasso 5 0.01 4.6e-02 -6.0 -5.8 8.9e-09 -0.06 0.02 0.94 FALSE
9 GTEx Lung MEAF6 0.11 0.10 lasso 3 0.10 2.9e-08 -5.8 -5.8 6.0e-09 -0.10 0.02 0.98 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic MEAF6 0.13 0.11 lasso 2 0.09 7.9e-06 -5.8 -5.8 8.5e-09 -0.11 0.02 0.96 FALSE
11 GTEx Spleen MEAF6 0.24 0.18 lasso 3 0.14 2.2e-04 -6.0 -5.5 3.4e-08 -0.07 0.02 0.91 FALSE
12 GTEx Stomach MEAF6 0.17 0.09 lasso 7 0.11 6.5e-06 2.9 -5.5 3.5e-08 -0.06 0.07 0.89 FALSE
13 GTEx Whole Blood FHL3 0.24 0.20 enet 20 0.23 3.1e-21 6.2 5.3 1.2e-07 0.90 0.00 1.00 FALSE
14 GTEx Whole Blood SF3A3 0.16 0.08 lasso 4 0.09 2.3e-08 6.2 5.5 4.7e-08 0.92 0.00 1.00 FALSE
15 NTR Blood MEAF6 0.05 0.02 lasso 3 0.03 3.9e-11 3.2 -5.2 2.5e-07 -0.05 0.90 0.09 FALSE
16 ROSMAP Brain Pre-frontal Cortex EPHA10 0.10 0.06 enet 34 0.07 1.2e-09 -2.5 5.2 1.8e-07 0.44 0.97 0.02 FALSE
17 YFS Blood FHL3 0.69 0.49 enet 33 0.57 8.2e-237 6.2 5.5 3.4e-08 0.90 0.00 1.00 TRUE
18 YFS Blood GNL2 0.06 0.06 lasso 12 0.06 2.0e-20 -5.7 -5.3 8.6e-08 -0.05 0.03 0.97 FALSE
19 The Cancer Genome Atlas Bladder Urothelial Carcinoma GNL2 0.03 0.01 enet 4 0.03 1.2e-03 -5.7 -5.4 8.1e-08 -0.07 0.01 0.92 FALSE
20 The Cancer Genome Atlas Bladder Urothelial Carcinoma MEAF6 0.10 0.02 blup 45 0.07 1.6e-06 3.0 -6.4 1.9e-10 -0.04 0.01 0.93 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma GNL2 0.08 0.09 lasso 3 0.09 1.0e-10 -5.7 -5.7 1.5e-08 -0.09 0.00 1.00 FALSE
22 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MEAF6 0.08 0.03 enet 8 0.06 2.0e-07 2.9 -5.7 1.6e-08 -0.04 0.02 0.97 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma GNL2 0.04 0.04 lasso 1 0.03 1.2e-04 -5.7 -5.7 9.5e-09 -0.10 0.00 0.99 FALSE
24 The Cancer Genome Atlas Lung Squamous Cell Carcinoma MEAF6 0.03 0.01 lasso 2 0.01 1.7e-02 3.2 -5.2 1.9e-07 -0.05 0.02 0.66 FALSE
25 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma GNL2 0.07 0.00 blup 48 0.01 3.8e-02 -5.7 -5.8 4.8e-09 -0.02 0.01 0.62 FALSE
26 The Cancer Genome Atlas Pancreatic Adenocarcinoma MEAF6 0.12 0.06 blup 45 0.08 3.5e-04 -5.8 -5.9 3.7e-09 -0.05 0.01 0.88 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma GNL2 0.07 0.00 enet 15 0.01 1.5e-02 4.1 -5.5 3.4e-08 -0.02 0.01 0.31 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma MEAF6 0.22 0.09 enet 9 0.15 8.8e-15 3.2 -5.1 2.9e-07 0.02 0.99 0.00 FALSE