Best TWAS P=2.09e-10 · Best GWAS P=1.96e-10 conditioned to 0.000291
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | PABPC4 | 0.01 | 0.00 | blup | 383 | 0.00 | 2.8e-02 | 4.4 | -6.3 | 2.1e-10 | 0.15 | 0.09 | 0.05 | TRUE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | BMP8A | 0.04 | 0.03 | blup | 48 | 0.04 | 3.5e-05 | 3.9 | 5.3 | 1.2e-07 | 0.01 | 0.01 | 0.76 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | MFSD2A | 0.08 | 0.02 | enet | 10 | 0.06 | 1.2e-06 | 3.1 | 5.5 | 2.8e-08 | -0.72 | 0.09 | 0.88 | TRUE |