Best TWAS P=7.46e-09 · Best GWAS P=2.02e-05 conditioned to 0.0074
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | YFS | Blood | CTSB | 0.49 | 0.13 | enet | 54 | 0.43 | 1.3e-155 | 1.3 | 5.8 | 7.5e-09 | -0.29 | 0.04 | 0.00 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CTSB | 0.05 | 0.02 | blup | 61 | 0.03 | 1.1e-04 | 3.5 | -5.3 | 1.3e-07 | 0.44 | 0.00 | 0.05 | FALSE |