TWAS hub - CTSB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1260	0.0390	1.4e-08	0.098	0.070	0.095	0.088	0.094	6.4e-12	6.7e-09	1.4e-11	6.6e-11	1.5e-11
2	GTEx	Brain Nucleus accumbens basal ganglia	0.4130	0.1260	2.7e-03	0.077	NA	0.134	NA	0.077	4.3e-03	NA	1.9e-04	NA	4.3e-03
3	GTEx	Cells Transformed fibroblasts	0.4600	0.0590	6.3e-15	0.123	NA	0.323	NA	0.320	1.8e-09	NA	7.7e-25	NA	1.7e-24
4	GTEx	Esophagus Mucosa	0.1600	0.0560	1.8e-03	0.043	NA	0.141	NA	0.121	6.8e-04	NA	1.1e-09	NA	1.7e-08
5	GTEx	Esophagus Muscularis	0.4030	0.0700	1.8e-08	0.183	NA	0.204	NA	0.223	2.6e-11	NA	1.7e-12	NA	1.1e-13
6	GTEx	Heart Atrial Appendage	0.2590	0.0740	2.3e-04	0.077	NA	0.092	NA	0.108	2.5e-04	NA	6.6e-05	NA	1.5e-05
7	GTEx	Nerve Tibial	0.4091	0.0692	6.3e-09	0.086	NA	0.110	NA	0.115	1.1e-06	NA	3.4e-08	NA	1.6e-08
8	GTEx	Skin Not Sun Exposed Suprapubic	0.2170	0.0840	2.6e-03	0.055	NA	0.031	NA	0.068	5.7e-04	NA	8.3e-03	NA	1.4e-04
9	GTEx	Skin Sun Exposed Lower leg	0.1580	0.0490	5.9e-04	0.049	NA	0.046	NA	0.028	6.7e-05	NA	9.9e-05	NA	2.2e-03
10	GTEx	Spleen	0.4160	0.1390	1.2e-03	0.238	NA	0.200	NA	0.148	8.5e-07	NA	7.6e-06	NA	1.2e-04
11	GTEx	Testis	0.1710	0.0650	4.8e-03	0.166	NA	0.118	NA	0.151	7.6e-08	NA	7.0e-06	NA	3.4e-07
12	GTEx	Whole Blood	0.1180	0.0400	3.5e-04	0.036	NA	0.063	NA	0.064	2.6e-04	NA	1.8e-06	NA	1.6e-06
13	METSIM	Adipose	0.0792	0.0261	2.9e-04	0.013	0.023	0.015	0.026	0.019	4.4e-03	2.0e-04	2.2e-03	6.3e-05	7.1e-04
14	NTR	Blood	0.0364	0.0143	1.7e-03	0.007	0.010	0.008	0.010	0.009	1.8e-03	3.2e-04	7.9e-04	1.9e-04	4.0e-04
15	ROSMAP	Brain Pre-frontal Cortex	0.1762	0.0360	0.0e+00	0.142	0.167	0.169	0.170	0.166	8.7e-18	6.6e-21	3.8e-21	3.0e-21	7.7e-21
16	YFS	Blood	0.4935	0.0350	0.0e+00	0.131	0.395	0.428	0.393	0.406	1.4e-40	7.8e-140	1.3e-155	6.9e-139	4.5e-145
17	TCGA	Bladder Urothelial Carcinoma	0.0470	0.0250	2.7e-03	0.016	0.020	0.021	NA	0.015	1.4e-02	7.2e-03	5.8e-03	NA	1.8e-02
18	TCGA	Breast Invasive Carcinoma	0.0405	0.0152	3.6e-09	0.041	0.048	0.040	NA	0.043	7.3e-09	3.4e-10	1.0e-08	NA	2.8e-09
19	TCGA	Kidney Renal Clear Cell Carcinoma	0.0465	0.0201	3.5e-04	0.016	0.033	0.030	NA	0.020	5.9e-03	1.0e-04	2.2e-04	NA	2.0e-03
20	TCGA	Brain Lower Grade Glioma	0.0357	0.0173	9.3e-04	0.009	0.027	0.016	NA	0.017	3.2e-02	4.5e-04	6.1e-03	NA	4.4e-03
21	TCGA	Lung Adenocarcinoma	0.0645	0.0271	4.0e-05	0.040	0.045	0.032	NA	0.033	1.6e-05	4.5e-06	1.1e-04	NA	8.0e-05
22	TCGA	Prostate Adenocarcinoma	0.0913	0.0340	6.5e-08	0.077	0.074	0.068	NA	0.082	2.0e-08	3.9e-08	1.2e-07	NA	6.3e-09

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Heel bone mineral density (BMD) T-score, automated (left)	9.6	21.7	45.2	-6.7	-5.4	-4.0	-0.9	-5.4	-2.3	-6.2	-5.7	-5.9	-5.3	-5.8	-1.0	-3.1	1.4	-4.9	0.3	-5.0	-5.2	0.6	-6.4	-5.0	-5.3
Heel bone mineral density (BMD) T-score, automated (right)	8.4	19.3	40.6	-6.4	-5.5	-3.6	0.1	-4.8	-2.0	-5.8	-5.6	-5.3	-5.0	-5.4	-0.5	-2.6	0.8	-5.0	-0.7	-4.7	-5.2	1.4	-6.3	-4.3	-5.0
Neuroticism (2016)	7.6	11.0	30.4	4.4	4.8	2.7	-0.0	3.5	0.6	3.8	5.5	3.0	3.2	3.8	-0.6	1.6	-0.7	4.2	0.1	3.0	4.1	-2.1	5.1	3.2	3.7
Hypothyroidism/myxoedema (self-reported)	7.4	14.5	27.6	5.2	5.2	3.5	1.0	4.5	2.6	4.8	4.5	4.1	4.3	4.6	1.3	2.4	-2.0	3.8	-1.4	3.9	3.8	0.4	5.1	4.6	4.6
Irritability	6.9	11.7	25.2	5.0	4.5	4.2	-0.8	3.7	0.3	4.2	4.5	3.3	3.2	3.4	1.5	1.6	-1.3	4.4	0.2	3.8	4.4	-2.0	4.7	3.4	3.4
Triglycerides	6.8	11.2	24.6	4.1	3.8	4.0	-0.5	3.8	0.9	4.2	1.6	2.1	3.4	3.4	1.7	3.5	-2.1	5.0	0.6	4.0	4.7	-1.6	4.9	4.0	3.3
Worrier / anxious feelings	6.8	12.9	30.5	5.0	4.6	3.6	-1.2	3.6	1.0	4.2	5.5	3.2	3.8	4.2	0.1	1.8	-0.7	4.6	0.7	3.3	4.2	-2.5	5.5	4.0	3.5
Primary Biliary Cirrhosis	6.5	9.3	16.3	-4.0	-3.6	-3.5	-0.5	-3.6	-3.1	-3.5	-1.7	-2.5	-3.6	-3.8	-2.0	-3.7	2.1	-2.5	0.4	-3.4	-3.5	-0.7	-3.8	-3.5	-3.5
Chronic bronchitis/emphysema (mother)	6.2	7.2	13.7	3.2	2.8	2.0	2.2	3.6	3.7	2.4	2.2	3.0	3.5	3.5	0.7	2.5	-1.7	0.6	-2.5	2.5	1.6	1.9	2.8	3.6	3.4
Impedance of leg (left)	5.8	28.2	66.7	7.3	6.5	3.0	1.6	6.2	3.0	6.3	8.2	6.4	5.8	6.9	-1.5	4.2	-1.2	5.4	-0.8	5.9	5.6	-0.6	7.0	5.3	6.3
Medication: Bendroflumethiazide	5.6	8.6	21.4	-4.0	-4.6	-3.3	-1.1	-3.5	-0.3	-3.8	-2.7	-1.8	-2.5	-2.6	-2.0	-2.4	0.5	-4.2	-0.4	-3.7	-3.8	1.2	-3.7	-2.6	-3.4
Medication: Levothyroxine sodium	5.5	9.2	16.6	4.1	3.2	2.7	1.3	3.8	2.0	4.0	3.6	3.5	3.6	3.7	1.0	1.9	-1.7	2.9	-1.2	3.6	2.9	0.6	3.8	3.8	3.6
Nervous feelings	5.5	10.3	28.5	4.5	4.7	2.6	0.2	3.5	1.2	3.4	5.3	4.4	3.5	3.8	-0.3	1.8	-0.8	3.2	-0.3	3.1	3.2	-1.1	4.3	3.3	3.6
Comparative body size at age 10	5.1	14.0	38.2	-5.1	-5.2	-2.3	-1.1	-4.5	-1.9	-4.6	-6.2	-4.6	-4.1	-4.6	0.7	-2.8	0.9	-3.1	0.8	-3.3	-3.4	0.2	-4.8	-4.1	-4.8
Impedance of leg (right)	5.0	24.4	61.5	7.0	6.0	2.7	1.2	5.6	2.8	5.9	7.8	6.2	5.5	6.5	-1.5	3.5	-1.1	4.9	-1.0	5.5	5.0	-0.4	6.5	5.1	5.7
Suffer from ‘nerves’	4.5	7.1	13.0	3.6	3.1	2.5	-0.2	2.9	1.3	3.2	3.3	3.6	3.0	3.1	0.6	1.9	-0.1	3.1	0.7	3.3	3.0	-0.7	3.5	2.8	3.1
Impedance of whole body	4.5	23.0	59.8	6.8	6.2	3.2	0.1	5.1	1.7	5.6	7.7	5.3	4.8	6.0	-1.4	3.8	-0.7	5.7	0.1	5.0	5.6	-2.2	6.8	4.4	5.2
Birth weight of first child	4.3	7.9	16.0	2.9	1.5	2.2	1.7	3.7	2.5	3.7	0.6	1.0	3.5	3.2	0.9	3.9	-3.5	3.1	-0.2	4.0	3.5	0.6	3.6	2.9	3.1
Ever highly irritable/argumentative for 2 days	4.2	5.1	9.4	3.0	2.5	1.2	1.5	2.9	2.2	2.2	3.1	2.5	2.5	2.8	0.7	1.8	-1.8	0.4	-2.8	1.9	1.0	2.2	1.9	2.7	2.9
Supplements: Vitamin C	4.1	4.9	19.4	-1.9	-1.6	-3.0	4.4	-0.1	1.3	-2.2	0.1	-0.1	-0.7	-0.3	-2.2	-1.4	0.1	-3.9	-2.4	-1.8	-3.7	3.6	-2.6	0.1	-0.1
Medication: Blood pressure	4.1	7.9	17.1	-3.7	-4.1	-3.3	0.4	-2.8	-0.3	-3.8	-2.8	-1.2	-2.9	-2.5	-1.2	-2.6	0.3	-4.0	-1.6	-3.5	-3.8	1.8	-3.7	-2.5	-2.7
Mouth/teeth dental problems: Mouth ulcers	4.0	6.4	13.4	2.8	2.7	2.4	2.4	3.6	2.4	2.8	1.2	2.4	2.8	2.8	1.5	2.2	-1.6	2.1	-1.3	2.9	2.1	1.6	2.7	3.7	3.7
Mood swings	3.9	7.1	14.0	3.7	3.5	3.2	0.3	3.1	1.0	3.0	2.8	2.6	2.6	2.9	1.2	1.9	-0.6	3.2	1.0	2.9	3.3	-0.7	3.7	3.1	3.1
Tense / ‘highly strung’	3.8	6.2	15.6	3.6	3.8	2.3	-1.3	2.2	0.6	2.9	4.0	3.1	2.3	2.8	-0.1	1.4	-0.8	3.1	0.3	2.3	2.9	-1.4	3.5	2.2	2.4
Impedance of arm (right)	3.7	17.4	45.9	6.0	5.5	3.2	-1.2	3.9	1.2	4.8	6.8	4.2	3.9	5.1	-1.1	3.2	-0.7	5.1	0.5	4.1	5.2	-2.8	6.3	3.8	4.2
Pulse wave peak to peak time	3.7	4.3	13.1	2.2	2.4	1.8	-0.2	1.6	1.2	2.9	-0.3	1.7	2.3	1.9	1.4	2.4	-2.1	3.6	1.5	3.0	2.8	0.3	2.4	2.0	1.6
Sensitivity / hurt feelings	3.6	6.1	19.4	3.4	4.4	3.4	-1.6	2.3	0.2	2.6	2.1	2.0	1.9	2.3	1.9	1.5	0.1	3.5	1.3	2.2	3.2	-1.7	3.5	2.4	1.9
Average weekly fortified wine intake	3.5	4.1	10.5	2.3	3.2	1.5	-0.3	2.4	0.2	2.4	2.6	1.7	1.7	2.0	-0.1	1.8	-0.1	2.4	0.6	1.6	2.9	-1.3	3.2	1.4	2.8
High blood pressure	3.5	9.7	21.3	-4.5	-4.3	-3.7	-0.2	-3.3	0.0	-4.6	-3.2	-2.6	-2.9	-2.8	-1.2	-2.8	0.5	-4.5	-1.0	-3.8	-3.8	2.1	-3.9	-2.8	-2.9
Neuroticism score	3.5	7.3	31.0	3.5	3.7	2.2	-1.0	2.5	-1.0	2.9	5.6	3.1	2.0	2.5	-0.9	0.2	0.4	3.5	1.1	2.1	2.9	-3.0	3.8	2.4	2.5
Impedance of arm (left)	3.4	15.8	37.5	5.6	5.3	3.3	-1.1	3.8	0.6	4.7	6.1	3.6	3.5	4.6	-0.7	3.0	-0.6	5.4	0.9	3.9	5.2	-3.3	6.1	3.4	3.8
Systolic blood pressure, automated reading	3.3	9.7	19.2	-4.2	-3.4	-2.9	0.2	-3.2	-0.3	-3.9	-3.9	-3.6	-3.3	-3.0	0.4	-3.6	0.4	-4.4	-1.0	-4.1	-3.6	1.9	-4.1	-3.0	-3.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	3.3	3.9	7.8	2.8	2.0	2.5	1.0	2.3	1.0	2.7	2.1	2.3	2.3	2.2	1.9	1.5	-1.6	1.5	-0.9	2.0	1.4	0.9	1.8	2.5	2.2
Hypertension (Self-reported)	3.2	9.0	21.6	-4.3	-4.2	-3.6	0.2	-3.1	0.2	-4.5	-2.9	-2.3	-2.7	-2.6	-1.1	-2.6	0.5	-4.6	-1.2	-3.7	-3.8	2.3	-3.8	-2.7	-2.6
Diastolic blood pressure, automated reading	3.2	10.0	28.1	-3.9	-3.4	-3.4	1.5	-2.6	0.2	-3.9	-3.7	-2.8	-3.1	-2.7	-0.2	-2.6	1.2	-5.3	-2.1	-4.1	-4.2	3.3	-4.4	-2.8	-2.6
Headache pain in last month	3.1	5.3	11.0	3.1	1.5	1.9	1.9	3.0	1.6	2.7	3.0	3.2	2.6	2.8	0.3	1.6	-1.1	1.0	-1.9	2.5	1.2	1.9	2.1	3.0	3.3
Medication: Blood pressure	3.0	5.2	12.6	-3.3	-2.7	-2.6	-0.1	-2.5	-0.2	-3.6	-2.2	-2.2	-2.1	-2.2	-0.8	-1.9	0.9	-3.4	-0.2	-2.8	-2.9	0.8	-2.9	-2.1	-2.4
Age at last live birth	2.9	4.2	18.6	2.2	3.2	1.3	-0.2	1.3	-0.7	2.7	1.4	1.3	1.6	1.4	0.2	1.3	-0.4	4.3	2.4	2.4	3.5	-2.2	2.6	0.2	1.2
Smoking status: Current	2.9	4.5	13.7	-2.5	-3.6	-2.3	1.2	-2.1	0.2	-2.3	-3.0	-1.0	-1.5	-1.8	-0.1	-0.4	0.2	-3.0	-0.7	-1.2	-3.0	2.4	-3.7	-1.8	-2.4
Pulse wave Arterial Stiffness index	2.8	3.3	9.9	-1.8	-2.1	-1.4	0.0	-1.3	-1.2	-2.5	0.6	-1.6	-2.0	-1.6	-1.2	-2.1	2.1	-3.2	-1.4	-2.6	-2.3	-0.5	-1.9	-1.7	-1.3
Average weekly beer plus cider intake	2.8	4.1	13.5	2.6	1.7	1.4	0.6	2.0	1.1	2.6	3.7	3.6	2.2	2.5	-0.3	0.9	-0.8	1.4	-0.8	2.1	1.7	-0.3	2.3	2.2	2.5
Frequency of depressed mood in last 2 weeks	2.7	3.8	7.5	2.7	1.8	2.7	-0.6	2.2	0.7	1.8	2.3	2.4	1.7	2.1	0.5	1.7	-1.0	2.3	0.2	2.2	2.5	-0.8	2.7	2.5	2.2
Vascular/heart problems diagnosed by doctor	2.7	7.3	17.7	3.8	3.4	3.4	-0.4	2.7	-0.2	4.1	2.5	1.8	2.4	2.2	1.2	2.5	-0.7	4.2	1.3	3.5	3.5	-2.1	3.4	2.5	2.3
Prostate Cancer	2.6	3.6	8.0	-2.4	-2.0	-1.3	-1.8	-2.8	-1.4	-1.9	-2.6	-1.6	-2.0	-2.2	0.0	-2.3	1.5	-1.2	0.9	-1.9	-1.4	-0.4	-2.2	-2.7	-2.4
Peak expiratory flow (PEF)	2.5	5.7	12.9	3.1	2.6	2.9	-0.8	2.3	-0.2	3.4	2.4	1.8	2.5	1.9	0.8	1.9	-0.4	3.5	2.1	2.2	2.9	-1.8	3.6	2.9	2.4
Supplements: Fish oil (including cod liver oil)	2.5	3.3	7.1	-2.5	-2.6	-1.4	-0.9	-2.3	-0.2	-2.5	-2.0	-1.9	-2.0	-1.8	-0.1	-1.5	0.8	-2.2	0.6	-2.7	-2.0	0.1	-2.0	-1.6	-2.2
Medication: Ibuprofen (e.g. Nurofen)	2.4	3.1	8.4	2.0	1.0	0.5	1.3	1.8	2.4	1.5	2.9	2.8	2.1	2.3	-0.6	1.7	-1.4	-0.2	-1.6	1.7	0.6	1.6	1.2	1.8	2.2
Emphysema/chronic bronchitis	2.4	2.7	7.7	-1.7	-2.5	-2.5	1.8	-1.1	0.3	-1.5	-0.5	0.0	-0.9	-0.9	-1.5	-0.5	0.3	-2.8	-1.1	-1.3	-2.6	2.2	-2.7	-1.6	-1.2
Medication: Ibuprofen	2.4	2.8	7.9	1.6	0.2	0.5	0.5	1.2	2.8	1.4	2.3	2.6	2.2	2.2	-0.2	1.6	-2.3	-0.2	-1.8	2.0	0.6	1.8	1.0	1.7	1.9
Ulcerative Colitis (UC)	2.2	4.0	13.4	-1.7	-0.8	0.2	-2.9	-2.2	-3.4	-0.8	-1.0	-2.0	-2.4	-2.4	0.1	-1.6	1.8	1.5	3.7	-1.1	0.4	-3.6	-0.5	-1.9	-1.9
Bipolar Disorder (2011)	2.2	2.1	6.1	1.2	1.2	2.4	-0.5	1.0	1.4	1.2	-1.2	0.6	1.3	1.2	2.5	2.1	-1.5	1.3	-0.4	2.1	2.0	0.5	1.4	1.4	1.2
Ulcerative Colitis	2.2	3.2	13.8	0.5	0.7	2.3	-3.7	-0.9	-1.8	1.1	-0.5	-0.4	-0.4	-0.6	1.7	0.3	0.2	3.4	3.0	0.8	2.4	-3.3	1.6	-0.1	-0.5
Current tobacco smoking	2.2	3.6	10.9	-2.2	-3.1	-1.9	1.4	-1.6	0.7	-1.8	-3.2	-0.9	-0.9	-1.4	0.3	-0.1	-0.5	-2.8	-1.1	-0.8	-2.6	2.6	-3.3	-1.4	-2.0
Pulse rate	2.2	3.6	9.0	2.0	2.4	1.7	1.9	3.0	1.3	1.8	1.6	1.7	1.8	2.3	0.8	2.3	0.0	0.7	-1.9	2.2	1.5	1.6	1.8	2.3	3.0
Tinnitus: Yes, now most or all of the time	2.2	2.6	4.9	1.8	0.9	2.0	1.0	2.1	1.3	2.2	-0.2	1.9	1.9	1.6	1.8	1.6	-1.2	1.4	-0.5	2.2	1.6	0.8	1.5	1.9	2.0
Unable to work because of sickness or disability	2.2	2.8	12.0	-1.9	-3.5	-1.0	-1.5	-1.9	-0.7	-2.0	-1.7	-0.8	-1.6	-1.8	-0.0	-1.7	0.4	-2.1	-0.6	-0.8	-1.9	0.8	-2.6	-1.6	-2.1
Average weekly spirits intake	2.1	2.6	5.7	2.1	1.9	1.8	0.8	2.3	0.8	1.8	1.3	1.0	2.1	1.9	1.1	1.8	-0.1	1.5	-0.4	2.4	1.8	0.1	1.8	1.9	1.8
Diabetes (father)	2.1	2.6	7.0	-1.9	-2.1	-1.9	-0.0	-1.9	-0.5	-1.6	-0.6	-1.1	-1.9	-1.6	-0.5	-1.7	0.7	-2.5	-0.4	-2.5	-2.6	0.4	-2.1	-1.0	-1.6
Serious illness, injury or assault to yourself	2.1	2.6	5.0	1.9	0.2	1.4	1.0	2.0	1.8	1.7	2.0	1.7	2.1	2.1	0.6	2.1	-1.0	0.2	-1.2	2.0	1.2	1.1	1.7	2.2	1.6
High blood pressure (mother)	2.1	3.0	9.1	-2.0	-1.8	-1.0	-2.0	-2.3	-1.1	-2.0	-3.0	-1.7	-1.6	-2.1	0.6	-2.1	0.1	-0.8	1.3	-2.0	-1.0	-0.7	-1.5	-1.7	-2.3
Mouth/teeth dental problems: Bleeding gums	2.1	2.7	7.5	-2.2	-2.7	-2.0	-0.1	-1.8	-0.3	-2.1	-1.5	-0.7	-1.6	-1.4	-1.2	-0.8	0.3	-2.1	-0.9	-1.8	-2.3	1.0	-2.3	-1.5	-1.8
Number of children fathered	2.1	2.4	7.7	-1.4	-2.1	-0.8	0.6	-0.9	-0.9	-1.4	-0.4	-1.2	-1.7	-1.6	0.5	-2.1	1.8	-2.8	-0.3	-2.1	-2.7	0.8	-2.2	-0.8	-1.0
Risk taking	2.1	3.0	6.3	-2.2	-2.4	-1.5	0.6	-1.6	-1.6	-2.1	-2.5	-2.4	-1.9	-2.3	-0.3	-0.3	1.8	-0.8	1.8	-1.6	-1.4	-0.0	-2.1	-1.9	-1.7
Body mass index (BMI)	2.0	8.5	22.4	-3.4	-4.2	-1.3	0.1	-2.7	0.1	-3.5	-4.7	-3.2	-2.6	-3.1	2.1	-0.7	0.2	-4.3	-1.5	-2.9	-3.6	3.0	-4.3	-2.4	-2.7
Mouth/teeth dental problems: Dentures	2.0	3.3	6.6	-2.5	-1.7	-1.4	-0.6	-2.3	-1.2	-2.5	-2.1	-2.4	-2.2	-2.3	0.1	-1.2	0.9	-1.6	0.0	-2.0	-1.9	0.3	-2.6	-2.4	-2.1
Handedness (chirality/laterality): Left-handed	2.0	2.4	5.2	1.4	1.2	1.8	0.9	1.6	1.6	1.9	-0.7	0.9	1.9	1.5	2.3	1.7	-2.0	0.8	-0.8	1.6	1.4	1.4	1.4	2.3	1.5
Miserableness	2.0	3.4	17.4	2.4	2.0	0.7	0.0	1.9	-0.1	1.5	4.2	2.8	1.6	2.2	-1.7	-0.2	0.0	2.0	0.1	1.5	1.7	-1.4	2.4	1.7	2.2
Coronary Artery Disease (CAD)	1.9	2.2	8.3	-0.3	-0.6	-2.1	2.3	-0.1	0.5	-0.7	2.9	1.7	-0.4	0.2	-2.4	-0.6	-0.3	-2.5	-2.1	-1.2	-2.1	1.5	-1.1	-0.2	0.6
Lupus	1.9	2.9	9.6	-2.2	-1.5	-0.6	0.8	-1.0	0.5	-1.6	-3.1	-2.3	-1.5	-1.7	1.2	-1.1	1.0	-2.9	-1.3	-1.9	-1.9	1.7	-2.1	-0.9	-1.6
Pulse wave reflection index	1.9	2.3	6.6	-1.9	-2.6	-1.6	0.8	-1.0	-0.7	-1.9	-0.2	-0.9	-1.3	-1.6	-1.0	-1.9	0.8	-2.4	-0.7	-2.2	-1.9	-0.1	-1.7	-1.6	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.9	4.0	10.3	2.1	2.6	2.8	0.2	2.0	-1.1	2.2	0.8	0.2	1.3	0.7	1.5	1.1	0.0	3.0	2.8	1.9	3.2	-2.5	2.9	1.7	2.0
Medication: Co-codamol	1.8	2.1	7.2	-0.7	-0.7	0.5	-2.7	-1.8	-1.8	-1.2	-1.7	-1.1	-2.0	-1.7	1.0	-1.3	1.5	-0.2	1.0	-1.4	-0.7	-1.5	-1.1	-1.5	-2.3
Fed-up feelings	1.8	3.3	9.0	2.8	1.7	1.5	0.7	2.4	0.2	2.1	3.0	2.3	1.7	2.4	-0.3	-0.2	0.6	1.7	-0.0	1.9	1.8	-0.9	2.4	2.2	2.1
Lung cancer (father)	1.8	2.1	5.7	0.9	-0.1	-0.2	2.3	1.6	2.0	1.1	1.1	2.0	1.5	1.4	0.0	0.6	-1.9	-0.9	-2.4	1.0	0.0	2.3	0.2	1.0	1.8
Time employed in main current job	1.7	2.0	7.5	1.2	0.4	-0.8	0.1	0.6	1.2	1.2	2.7	2.4	1.8	1.6	-1.9	0.4	-2.4	0.3	-1.9	1.4	0.5	0.4	1.0	0.9	1.3
Worry too long after embarrassment	1.7	2.8	26.0	1.4	1.1	-0.3	0.2	1.2	-0.9	1.2	5.1	2.6	1.0	1.2	-2.7	-0.7	1.3	1.2	0.6	0.5	0.9	-1.9	1.5	0.6	1.1
Age at first live birth	1.7	3.0	11.1	2.2	3.3	1.2	0.8	1.6	-0.4	2.3	1.7	1.5	1.4	1.4	0.1	0.9	0.4	3.3	1.3	1.9	2.3	-1.2	2.0	0.5	1.6
Irritable Bowel Disease (IBD)	1.6	3.8	9.2	-1.9	-1.1	-0.3	-2.2	-2.3	-3.0	-1.4	-1.3	-2.0	-2.7	-2.7	0.3	-2.0	1.6	0.2	2.6	-1.8	-0.6	-2.7	-1.4	-2.1	-2.2
Vitamin and mineral supplements	1.6	2.2	6.8	1.9	1.8	2.3	-1.6	1.0	-0.7	1.6	-0.1	0.5	0.9	0.6	1.5	1.1	-0.5	2.6	1.2	1.5	2.3	-1.9	2.1	0.9	0.6
Age when periods started (menarche)	1.6	3.8	10.2	2.4	1.2	2.2	-0.7	1.8	0.7	3.1	0.6	0.5	2.4	2.0	1.5	2.5	-0.6	2.6	0.7	2.9	3.2	-1.1	2.7	1.2	1.4
Tinnitus: Yes, but not now, but have in the past	1.6	1.7	7.0	-1.8	-2.6	-1.2	-0.8	-1.5	-0.8	-1.2	-0.5	-1.5	-1.1	-1.5	-1.1	-1.3	1.0	-1.4	0.6	-1.2	-1.2	-0.1	-1.6	-1.4	-1.1
Stomach or abdominal pain in last month	1.6	2.0	3.8	1.6	0.1	0.7	-1.1	1.0	0.8	1.8	1.9	1.9	1.7	1.5	-0.1	1.6	-1.5	1.8	-1.0	1.9	1.5	-0.3	1.8	1.2	1.3
Fluid intelligence score	1.6	3.4	7.4	1.9	1.5	2.0	0.1	2.0	0.9	2.4	1.2	1.8	2.1	1.9	0.4	2.1	-1.6	2.7	1.0	2.3	2.2	-0.4	2.6	2.4	1.9
Medication: Amlodipine	1.6	2.2	9.3	-2.4	-2.0	-1.0	-1.3	-1.9	-0.7	-1.9	-3.1	-1.5	-1.4	-2.0	0.6	-1.0	-0.7	-0.5	0.9	-0.9	-0.6	-0.2	-1.4	-1.4	-1.8
Heart disease (mother)	1.6	1.9	6.2	-0.8	-0.4	-1.3	-0.3	-1.4	-0.7	-1.7	1.3	-0.1	-1.0	-0.9	-1.6	-2.5	1.8	-2.0	-0.6	-1.9	-2.5	0.5	-1.6	-0.5	-0.9
Medication: Aspirin	1.6	2.0	4.7	-2.2	-0.9	-1.4	-0.2	-1.7	-0.9	-2.0	-1.6	-0.9	-1.4	-1.7	-0.5	-1.4	0.8	-1.4	-0.1	-1.9	-1.7	0.1	-1.9	-1.8	-1.8
Schizophrenia (2014)	1.5	3.4	11.8	-2.5	-3.4	-2.2	0.8	-1.7	0.7	-2.4	-1.3	-0.4	-1.3	-1.3	-0.8	-0.4	-0.7	-3.1	-1.7	-1.4	-2.7	2.0	-2.6	-1.0	-1.7
Neuroticism	1.5	3.6	10.4	-1.7	-0.6	-1.7	-0.4	-1.8	-2.5	-2.4	0.5	-0.9	-2.5	-2.0	-1.3	-2.2	3.2	-1.9	0.8	-2.3	-2.0	-1.2	-2.1	-2.3	-1.9
Other serious medical condition/disability diagnosed by doctor	1.5	1.9	4.6	2.2	1.6	1.4	0.7	1.5	1.5	1.5	1.4	1.2	1.7	1.7	1.1	1.0	-0.8	0.7	-1.9	1.6	0.7	1.1	1.0	1.4	1.4
Leg fat-free mass (left)	1.5	8.0	25.3	-3.5	-4.1	-0.6	-1.8	-3.2	-1.6	-2.9	-5.0	-4.0	-2.9	-3.7	2.3	-1.5	0.3	-2.5	1.0	-2.9	-2.5	0.4	-3.4	-2.6	-3.2
Leg predicted mass (left)	1.5	7.9	25.7	-3.5	-4.0	-0.5	-1.8	-3.1	-1.6	-2.8	-5.1	-4.0	-2.9	-3.7	2.3	-1.5	0.2	-2.4	1.0	-2.9	-2.4	0.3	-3.3	-2.6	-3.2
Medication: Ramipril	1.5	2.0	7.3	-2.1	-1.8	-0.4	0.3	-1.2	-0.3	-1.3	-2.7	-1.7	-0.9	-1.6	1.6	-1.5	-0.1	-1.5	0.6	-1.2	-1.5	0.9	-2.0	-1.1	-1.2
Mineral and other dietary supplements	1.5	2.1	5.2	2.0	2.2	1.9	-0.1	1.5	-0.4	1.8	1.2	1.1	1.5	1.0	0.7	0.8	-0.7	2.2	0.4	2.3	1.8	-0.9	1.7	1.4	1.1
Osteoarthritis (self-reported)	1.5	1.9	9.0	0.7	0.2	0.1	1.7	1.1	2.5	0.1	0.4	1.2	1.2	1.1	0.7	0.7	-1.9	-1.7	-3.0	0.7	-0.8	2.8	-0.4	1.1	1.0
Medication: Lisinopril	1.5	1.9	6.8	-1.4	-1.9	-1.9	0.8	-0.5	1.3	-1.5	-0.0	-0.0	-0.7	-0.4	-1.2	-1.3	-0.0	-2.6	-2.2	-1.3	-2.1	1.9	-1.6	-0.3	-0.3
Body Mass Index (BMI) (2010)	1.4	2.0	5.7	-1.3	-0.4	-0.9	0.4	-1.3	-0.4	-1.9	-1.7	-1.1	-1.6	-1.4	0.1	-1.4	0.6	-2.4	-1.4	-1.8	-2.1	1.4	-2.0	-1.0	-1.3
Medication for cholesterol, blood pressure or diabetes	1.4	2.4	6.2	1.8	1.0	1.7	-0.2	1.4	0.4	2.5	0.4	1.5	1.6	1.3	0.8	1.4	-2.1	2.4	0.3	2.3	2.2	-0.5	1.9	1.3	1.3
Health satisfaction	1.4	1.8	8.4	-1.1	-1.6	-1.4	1.5	0.3	0.3	-1.9	0.5	-0.6	-1.0	-0.4	-1.5	-0.8	1.4	-2.9	-0.7	-1.9	-2.1	1.5	-1.2	-0.1	0.5
Neck or shoulder pain in last month	1.4	2.0	5.7	1.2	0.6	1.2	0.4	1.3	2.0	1.4	-0.2	2.2	1.4	1.4	1.4	0.6	-2.4	0.3	-2.0	1.5	0.5	2.0	0.7	1.9	1.4
Leg fat-free mass (right)	1.4	7.6	24.8	-3.5	-3.9	-0.5	-1.6	-3.0	-1.7	-2.8	-5.0	-4.1	-2.9	-3.7	2.2	-1.4	0.3	-2.3	1.2	-2.9	-2.3	0.1	-3.2	-2.6	-3.0
Osteoporosis (self-reported)	1.4	1.7	4.3	1.7	2.1	1.2	-0.9	1.3	0.8	1.4	2.0	0.8	1.3	1.6	-0.2	0.1	0.7	1.5	0.2	1.2	1.5	-0.9	2.0	1.5	1.3
Leg predicted mass (right)	1.4	7.3	23.7	-3.5	-3.9	-0.5	-1.5	-2.9	-1.6	-2.8	-4.9	-4.0	-2.9	-3.6	2.2	-1.3	0.3	-2.3	1.1	-2.9	-2.3	0.1	-3.1	-2.5	-2.9
Guilty feelings	1.4	2.1	13.9	1.1	1.3	-0.7	-0.2	0.7	-1.1	1.0	3.7	2.0	0.5	0.9	-2.7	-1.1	1.4	1.7	0.8	0.7	0.9	-2.1	1.2	-0.0	0.6
Verbal and Numeric Reasoning (VNR)	1.3	3.2	6.0	2.0	1.0	1.8	0.2	1.8	1.3	2.2	1.6	1.9	2.4	2.1	0.0	2.3	-2.4	2.2	0.2	2.1	1.6	0.1	2.3	2.2	1.8
Bilateral oophorectomy (both ovaries removed)	1.3	1.6	5.7	-1.1	-1.7	0.3	-0.9	-0.7	-2.4	-1.2	-0.5	-1.5	-1.7	-1.7	0.1	-0.9	1.3	0.2	1.8	-1.1	-0.4	-1.9	-0.7	-1.2	-1.0
Leg pain on walking	1.3	1.7	8.0	-1.0	-1.0	-1.6	1.1	-0.6	-0.1	-1.2	0.0	-0.2	-0.6	-0.7	-0.8	-1.6	0.9	-2.8	-1.4	-1.5	-2.2	1.3	-1.9	-1.1	-0.6
Age started oral contraceptive pill	1.3	1.6	4.5	1.6	2.1	1.3	0.7	1.4	0.1	1.7	1.2	1.7	1.4	1.2	0.9	0.7	-1.5	1.5	-0.4	1.4	1.0	0.1	1.2	1.2	1.4
Schizophrenia (2018)	1.2	2.5	8.0	-1.8	-2.7	-2.1	1.7	-0.9	1.1	-2.1	-0.8	0.1	-0.9	-0.7	-1.1	0.0	-0.6	-2.8	-1.6	-1.2	-2.4	2.2	-2.1	-0.4	-1.2
Ever used hormone-replacement therapy (HRT)	1.2	1.6	5.9	1.5	0.6	0.8	-0.1	1.0	2.2	0.8	0.7	1.4	1.3	1.6	1.1	0.9	-0.9	-0.8	-2.4	0.4	-0.2	2.0	0.6	1.8	0.8
Sitting height	1.2	8.3	14.7	-3.5	-3.2	-3.1	-0.9	-3.4	-2.7	-3.2	-1.9	-2.1	-3.6	-3.4	-1.6	-3.1	3.4	-2.2	1.4	-3.8	-3.2	-0.3	-3.5	-3.6	-2.7
Alcohol usually taken with meals	1.2	1.9	3.8	-2.0	-0.9	-1.8	0.2	-1.6	-0.7	-1.7	-0.9	-1.5	-1.0	-1.5	-1.5	-0.7	1.1	-1.4	0.3	-1.8	-1.7	0.1	-1.7	-1.8	-1.6
Father’s age at death	1.2	1.6	9.6	1.4	2.3	-0.0	0.2	1.1	-0.4	1.3	3.1	0.8	0.7	1.0	-1.1	-0.1	0.9	1.5	0.3	0.7	1.0	-1.4	1.7	1.1	1.1
Serious illness, injury or assault of a close relative in last 2 years	1.2	1.4	6.2	1.5	0.5	0.9	-0.2	1.1	0.4	1.5	2.5	1.4	1.5	1.4	-0.3	0.7	-0.2	1.2	-0.1	1.4	0.9	-0.2	1.4	1.4	1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.2	1.3	6.1	-1.2	-1.5	-2.0	0.9	-0.4	1.3	-0.3	-1.4	0.1	0.1	-0.2	-1.2	0.5	-1.4	-1.1	-0.8	0.1	-1.4	2.5	-1.5	-0.1	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.5	6.0	1.1	0.9	0.7	1.1	1.3	2.0	0.9	0.1	2.0	1.3	1.1	1.3	1.0	-0.0	-0.7	-1.5	0.9	-0.4	2.4	-0.1	1.2	1.1
Crohns Disease (2017)	1.1	2.5	5.8	-1.7	-1.2	-1.2	-0.3	-1.5	-1.8	-1.6	-0.7	-1.4	-2.4	-2.2	-0.1	-2.0	1.2	-1.7	0.3	-2.2	-1.9	-0.5	-2.2	-1.8	-1.6
Mean Putamen Volume	1.1	1.2	3.4	-1.8	-1.1	-0.0	-1.7	-1.6	-0.2	-0.8	-1.5	-1.9	-0.5	-1.2	0.4	-1.6	-0.0	-1.0	1.1	-1.0	-1.1	0.1	-0.7	-0.1	-1.0
Type 2 Diabetes (T2D) (2012)	1.1	1.3	3.7	0.8	-0.3	1.2	1.1	1.3	1.3	1.1	-1.1	0.5	1.5	1.1	1.9	1.5	-0.3	-0.4	-1.3	1.5	0.3	1.8	0.4	1.3	0.8
Ever had hysterectomy (womb removed)	1.1	1.3	3.0	-1.3	-1.5	-0.5	-0.3	-1.3	-0.8	-1.7	-1.7	-1.2	-1.6	-1.4	0.7	-0.1	0.3	-0.8	0.3	-1.1	-1.1	-0.2	-1.5	-1.2	-1.4
Supplements: Glucosamine	1.1	1.5	3.8	1.1	0.1	0.3	1.7	1.3	1.9	1.0	0.9	1.9	1.4	1.5	0.3	1.2	-0.9	-0.7	-1.4	0.2	-0.3	1.9	0.5	1.2	1.6
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.7	1.2	1.0	1.6	-0.9	0.8	1.6	1.1	-0.2	1.0	1.5	0.9	1.9	1.9	-1.0	0.6	-0.1	0.8	0.9	0.7	1.2	1.2	0.6
Past tobacco smoking	1.1	1.9	7.5	1.1	1.8	1.4	-1.9	0.4	-1.9	1.1	0.2	-0.4	-0.1	-0.2	0.3	-0.1	1.1	2.5	1.9	0.7	2.1	-2.7	1.8	-0.3	0.5
Hair/balding pattern: Pattern 2	1.1	1.4	4.0	0.9	-0.2	0.9	0.8	1.4	1.8	1.1	0.3	1.2	1.2	1.2	0.8	1.2	-1.4	-0.8	-1.5	0.9	-0.2	2.0	0.4	1.9	1.4
Qualifications: None of the above	1.1	2.3	8.8	1.2	0.6	0.4	0.5	1.0	2.5	0.5	1.2	2.6	1.3	1.5	0.9	0.9	-1.5	-1.7	-2.9	0.5	-0.9	3.0	-0.1	1.5	1.2
Qualifications: A levels/AS levels or equivalent	1.1	2.4	6.4	1.6	1.1	0.6	1.9	2.0	0.4	2.2	1.7	1.5	1.8	1.4	-0.9	1.1	-2.5	2.1	-0.3	2.2	1.6	-0.2	1.6	1.1	1.7
Depression (self-reported)	1.1	1.3	3.8	1.3	0.8	1.9	-1.2	0.7	0.4	1.2	0.1	0.5	1.5	0.9	1.3	0.9	-0.1	1.8	0.5	1.4	1.5	-0.9	1.2	1.3	0.6
Wheeze or whistling in the chest in last year	1.1	1.9	5.4	-1.3	-1.7	-1.2	-0.4	-1.7	0.2	-2.0	-1.3	-0.3	-1.4	-1.0	0.1	-0.7	0.0	-2.3	-0.9	-1.5	-1.9	1.5	-2.3	-1.6	-1.5
Arm predicted mass (right)	1.1	5.7	15.4	-3.1	-3.7	-1.1	-0.3	-2.3	-1.1	-2.6	-3.9	-2.7	-2.4	-3.0	1.4	-1.8	0.4	-2.8	0.2	-2.6	-2.7	1.1	-3.2	-2.2	-2.3
Whole body water mass	1.1	6.2	18.0	-3.3	-3.8	-0.9	-1.1	-2.7	-1.5	-2.6	-4.2	-3.4	-2.6	-3.3	1.6	-1.8	0.2	-2.3	0.8	-2.6	-2.3	0.3	-3.0	-2.4	-2.6
Basal metabolic rate	1.1	6.0	17.7	-3.1	-3.7	-0.7	-1.2	-2.6	-1.3	-2.5	-4.2	-3.4	-2.5	-3.2	1.9	-1.5	0.3	-2.4	0.7	-2.6	-2.3	0.6	-3.0	-2.3	-2.5
Deep venous thrombosis (DVT) (self-reported)	1.1	1.4	5.3	-1.1	-1.3	-1.1	1.5	-0.4	0.2	-0.9	-1.2	-0.2	-0.6	-0.8	0.1	0.3	-0.5	-2.1	-1.7	-1.0	-2.0	2.3	-1.8	-0.3	-0.4
Schizophrenia vs Biploar Disorder	1.0	1.4	4.3	-0.8	-1.1	-1.8	1.5	-0.7	0.7	-1.0	0.3	0.3	-0.4	-0.4	-1.3	-0.5	-0.3	-1.9	-1.1	-1.1	-2.1	1.8	-1.8	-0.9	-0.4
HbA1C	1.0	1.1	2.2	-1.0	-1.1	-1.5	0.5	-0.9	-1.0	-0.9	-0.9	-0.3	-1.3	-1.0	-1.0	-1.4	0.3	-1.1	-0.1	-1.3	-1.3	0.1	-1.5	-1.3	-1.2
Forced expiratory volume in 1-second (FEV1)	1.0	3.2	11.0	1.8	1.4	2.5	-0.4	1.6	-1.9	2.1	1.4	0.1	0.9	0.3	0.9	0.5	0.7	2.5	3.3	0.9	2.3	-3.0	2.5	1.7	1.4
Length of working week for main job	1.0	1.1	4.1	-1.0	-1.7	-1.6	1.6	0.1	-0.2	-0.7	0.7	-0.7	-0.4	-0.3	-2.0	0.1	-0.0	-1.9	-1.2	-0.7	-1.2	0.5	-0.9	-0.9	0.3
Blood clot in the leg (DVT)	1.0	1.3	7.0	-0.6	-0.8	-0.8	1.8	-0.0	0.7	-0.4	-1.0	0.2	-0.0	-0.3	0.4	0.6	-0.7	-1.9	-2.1	-0.5	-1.8	2.7	-1.5	0.1	-0.0
Medication: Aspirin	1.0	1.3	3.7	-1.9	-0.5	-1.2	-0.2	-1.3	-0.6	-1.6	-1.9	-0.6	-1.0	-1.4	-0.2	-0.7	0.7	-0.9	0.3	-1.5	-1.2	0.2	-1.5	-1.7	-1.5
Whole body fat-free mass	1.0	5.9	17.9	-3.2	-3.7	-0.8	-1.1	-2.6	-1.4	-2.5	-4.2	-3.4	-2.5	-3.2	1.7	-1.7	0.2	-2.3	0.8	-2.6	-2.2	0.5	-3.0	-2.2	-2.5
Arm fat mass (left)	1.0	4.1	11.9	-2.1	-3.0	-0.4	-0.6	-2.0	0.1	-2.4	-3.4	-2.6	-1.7	-2.1	2.1	-0.0	-0.0	-2.9	-1.0	-2.0	-2.3	2.0	-2.8	-1.8	-2.0
Wears glasses or contact lenses	1.0	1.2	3.1	1.5	0.9	0.5	0.7	1.3	1.2	0.4	1.8	1.3	1.3	1.5	-0.6	1.3	-0.1	0.1	-1.4	0.9	1.0	0.1	1.3	1.0	1.1
Depression (Nagel 2018)	0.9	1.3	2.6	1.5	0.5	1.5	0.7	1.6	0.7	0.9	1.1	1.2	0.6	1.2	0.1	1.5	-1.0	1.1	0.7	1.4	1.2	0.0	1.4	1.6	1.5
Supplements: Zinc	0.9	1.0	4.1	-0.9	-0.8	-1.7	0.9	-0.6	1.2	-1.1	-0.0	0.3	-0.2	0.2	-1.1	-0.4	0.3	-1.6	-0.9	-0.9	-1.7	2.0	-1.2	-0.3	-0.4
Pack years adult smoking proportion	0.9	1.4	7.2	-1.2	-2.7	-1.7	0.5	-0.8	1.1	-0.8	-1.8	0.0	0.2	-0.1	-0.7	0.2	-0.9	-1.4	-0.7	-0.1	-1.4	1.9	-1.5	-0.6	-1.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	14.3	1.1	1.5	2.1	-0.8	1.0	-2.4	1.3	0.8	-0.4	-0.1	-0.5	0.9	-0.3	0.9	2.3	3.8	0.2	2.0	-3.5	1.9	1.0	0.8
Arm fat mass (right)	0.9	3.8	10.3	-1.8	-2.9	-0.5	-0.0	-1.7	0.5	-2.2	-3.1	-2.0	-1.5	-1.7	2.0	0.3	-0.1	-3.2	-1.5	-1.9	-2.4	2.5	-2.8	-1.6	-1.6
Medication: Paracetamol	0.9	1.4	6.1	1.0	-0.6	-0.1	0.5	0.9	1.4	1.1	2.3	2.5	1.4	1.4	-0.6	0.1	-1.6	-0.5	-1.3	0.6	-0.5	1.3	0.4	1.7	1.0
Eye problems/disorders: None of the above	0.9	1.1	3.0	1.2	1.2	0.7	0.8	1.0	1.5	1.7	-0.1	0.7	1.4	1.0	1.0	0.4	-1.0	0.7	0.3	1.2	0.5	1.3	0.7	1.7	0.8
Mouth/teeth dental problems: Loose teeth	0.9	1.1	5.9	-0.6	-0.4	-0.3	0.5	-0.4	1.2	-0.7	-1.3	-0.7	-0.0	-0.3	0.6	0.0	-1.9	-1.7	-1.6	-0.4	-1.1	2.4	-1.0	0.4	-0.1
Number of full sisters	0.9	1.1	3.5	-0.7	-1.9	0.4	-0.9	-1.1	-0.4	-0.8	-1.8	-0.4	-1.2	-1.0	1.7	-0.1	0.5	-1.2	-0.1	-1.0	-1.1	0.4	-1.5	-0.8	-1.0
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	3.5	1.4	0.6	0.9	-0.2	1.0	0.7	1.9	0.1	0.8	1.1	1.1	0.5	1.7	0.0	1.5	0.5	1.0	1.4	-0.2	1.5	0.7	1.2
Smoking status: Previous	0.9	1.4	4.9	0.0	-0.3	-0.6	1.9	0.6	1.9	-0.3	1.1	1.3	0.8	1.0	-0.2	0.3	-1.4	-1.9	-2.1	-0.4	-1.3	2.2	-0.4	1.0	0.4
Medication for cholesterol	0.9	1.3	5.9	0.5	1.1	0.9	-1.2	-0.1	-1.7	0.9	1.7	-0.5	0.0	-0.2	-0.3	0.5	1.4	1.8	2.4	0.5	1.1	-2.3	0.8	-0.2	0.1
Medication: Gliclazide	0.9	1.0	2.5	-1.1	-0.4	-1.4	0.7	-0.6	0.3	-1.6	-1.3	-0.4	-0.7	-0.9	-0.8	-0.5	0.1	-1.5	-0.3	-1.3	-1.5	0.7	-1.3	-1.1	-1.1
Arm fat-free mass (left)	0.9	4.4	12.7	-2.6	-3.3	-0.9	-0.3	-2.1	-0.5	-2.2	-3.6	-2.4	-1.8	-2.5	1.6	-1.3	0.1	-2.6	-0.2	-2.2	-2.4	1.5	-2.9	-1.8	-1.9
Cholesterol lowering medication	0.9	1.3	5.5	0.7	0.4	-1.0	1.5	1.0	1.5	0.0	1.3	1.9	0.8	1.5	-1.6	-0.1	-0.4	-0.8	-2.3	0.3	-0.4	1.6	0.4	0.9	1.1
Pain experienced in last month	0.9	1.4	4.7	-1.2	-0.3	-1.3	-0.2	-1.2	-1.4	-1.2	0.7	-1.2	-1.2	-1.0	-2.2	-1.1	1.7	-0.2	1.5	-1.2	-0.3	-2.0	-0.4	-1.3	-1.0
Supplements: Calcium	0.9	1.0	3.8	-0.9	-1.1	-1.7	-0.8	-0.9	0.2	-0.9	1.3	0.1	-0.5	-0.1	-1.9	-1.4	1.0	-1.3	-0.5	-1.0	-0.9	0.2	-0.6	-1.0	-0.5
Arm predicted mass (left)	0.9	4.8	13.5	-2.8	-3.5	-0.9	-0.3	-2.1	-0.6	-2.4	-3.7	-2.6	-2.0	-2.6	1.7	-1.4	0.2	-2.9	-0.2	-2.3	-2.5	1.5	-3.0	-1.9	-1.9
Fasting Glucose	0.8	0.9	4.3	1.0	1.2	1.3	-0.4	0.7	0.7	0.5	-1.6	-0.5	0.4	0.6	2.1	1.4	-0.3	0.7	0.1	0.8	1.3	0.2	1.1	1.2	0.4
Maternal smoking around birth	0.8	1.2	4.2	1.2	0.7	1.2	0.3	1.5	1.0	0.4	0.7	2.1	0.8	1.2	0.4	1.7	-0.9	0.3	-1.1	1.2	1.1	0.3	1.2	1.3	1.6
Chronic bronchitis/emphysema (father)	0.8	0.9	3.0	1.1	0.6	1.4	-0.6	0.8	1.1	1.3	-0.5	0.4	1.3	1.1	1.7	1.4	-0.5	0.8	-0.1	1.1	1.2	0.4	0.7	0.6	0.3
Weight	0.8	4.1	11.5	-2.1	-3.0	-0.2	-1.1	-2.1	-0.6	-2.2	-3.4	-2.7	-1.9	-2.4	2.2	-0.6	0.4	-2.5	-0.2	-2.2	-2.1	1.3	-2.6	-1.9	-2.0
Trunk fat-free mass	0.8	4.7	11.6	-2.9	-3.3	-1.0	-0.9	-2.4	-1.5	-2.2	-3.4	-2.9	-2.3	-3.0	1.1	-1.9	0.2	-2.0	0.7	-2.4	-2.1	0.3	-2.7	-2.1	-2.2
Hip circumference	0.8	3.4	7.8	-1.7	-2.8	0.2	-0.9	-1.8	-0.6	-2.0	-2.8	-2.3	-2.0	-2.1	2.4	-0.4	0.8	-2.6	-0.7	-2.1	-2.0	1.3	-2.4	-1.6	-1.6
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.2	3.5	1.6	0.9	1.8	-0.5	1.4	0.0	0.6	1.5	1.0	0.5	0.9	1.1	0.6	-0.3	1.0	0.3	1.0	1.2	-0.5	1.5	1.9	1.3
Trunk predicted mass	0.8	4.7	11.7	-2.9	-3.3	-1.0	-0.8	-2.3	-1.5	-2.2	-3.4	-2.8	-2.3	-2.9	1.1	-1.9	0.3	-2.0	0.7	-2.4	-2.1	0.3	-2.7	-2.1	-2.2
Breastfed as a baby	0.8	1.0	3.9	0.8	0.6	0.0	0.0	0.6	1.5	1.1	1.8	2.0	1.5	1.2	-0.4	-0.2	-1.0	-0.2	-1.4	0.5	0.1	0.7	0.6	0.7	1.0
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	4.7	1.4	1.4	0.6	0.2	0.9	-0.9	1.4	2.2	-0.2	0.6	0.5	-0.8	-0.3	-0.6	1.8	0.3	0.6	1.7	-1.8	1.5	-0.4	0.7
Arm fat-free mass (right)	0.8	4.3	13.6	-2.7	-3.3	-0.9	-0.1	-1.9	-0.7	-2.2	-3.7	-2.4	-2.0	-2.6	1.4	-1.3	0.2	-2.5	-0.0	-2.2	-2.3	1.2	-2.8	-1.8	-1.8
Medication for pain relief, constipation, heartburn	0.8	1.4	7.0	-0.9	-0.7	0.2	-1.0	-1.0	-1.8	-0.6	-1.6	-2.6	-1.4	-1.2	0.6	-0.4	0.9	0.5	1.1	-0.6	0.6	-1.9	-0.0	-1.2	-1.2
Leg fat mass (right)	0.8	2.9	9.3	-1.2	-2.5	0.0	0.1	-1.1	1.0	-1.6	-2.9	-1.6	-0.9	-1.2	2.4	0.5	-0.5	-2.7	-1.5	-1.1	-2.0	3.1	-2.4	-0.8	-1.2
Comparative height size at age 10	0.8	4.2	7.7	-2.4	-1.2	-1.1	-2.2	-2.6	-2.8	-2.2	-2.2	-2.0	-2.6	-2.5	0.1	-2.6	1.6	-0.5	2.4	-2.1	-1.0	-1.8	-1.7	-2.4	-2.3
Overall health rating	0.8	1.8	7.9	-0.9	-2.4	0.4	-0.1	-0.4	0.3	-1.5	-1.9	-0.4	-1.3	-0.9	2.0	0.2	0.3	-2.8	-1.2	-1.5	-1.6	1.7	-1.6	-0.3	-0.7
Friendships satisfaction	0.8	1.0	3.3	0.0	-0.9	-1.0	1.8	0.4	0.4	-0.5	1.2	0.9	-0.2	0.1	-0.8	-0.8	0.5	-1.6	-1.8	-0.4	-1.3	1.7	-0.9	-0.2	0.6
Back pain experienced in last month	0.8	1.2	3.2	1.3	0.3	1.6	0.2	1.2	0.9	0.7	-0.2	1.6	0.5	1.0	1.8	1.1	-1.3	-0.8	-1.7	-0.0	0.1	1.5	0.5	1.3	1.0
Mother’s age at death	0.8	1.0	2.8	1.3	1.6	-0.4	0.1	0.7	0.5	1.0	1.7	1.6	0.7	1.1	-1.0	1.0	0.7	1.0	-0.4	1.1	1.1	0.0	1.2	-0.1	0.8
Eye problems/disorders: Glaucoma	0.8	1.0	6.0	-1.7	-0.6	-0.5	-0.0	-0.7	-0.7	-1.4	-2.4	-1.4	-1.0	-1.2	0.2	-0.4	-0.3	-0.2	0.5	-0.3	-0.3	-0.2	-1.1	-1.2	-1.0
Pain type(s) experienced in last month: Hip pain	0.8	1.0	3.8	-1.0	-0.7	-1.0	0.7	-0.2	-0.2	-1.4	0.4	0.1	-1.3	-0.8	-0.2	-1.0	0.4	-2.0	-1.7	-1.3	-1.5	0.8	-1.4	-0.7	-0.1
Number of operations (self-reported)	0.8	1.2	7.1	-1.1	-2.7	-0.6	0.5	-0.6	0.7	-1.0	-0.7	-0.4	-0.5	-0.5	0.1	0.1	-0.9	-2.1	-1.5	-0.2	-1.5	1.4	-1.3	0.0	-0.7
Bipolar Disorder or Schizophrenia	0.7	1.6	6.1	-1.7	-2.5	-0.7	0.5	-1.0	0.7	-1.7	-1.9	-0.5	-1.0	-1.0	0.7	0.4	-0.9	-2.0	-0.9	-0.6	-1.4	1.6	-1.6	-0.1	-1.2
Intelligence (Savage-Jansen 2018)	0.7	2.2	4.0	1.9	1.1	1.6	0.0	1.5	1.4	1.5	1.5	1.7	1.9	2.0	0.4	1.7	-1.9	1.0	-0.7	1.7	1.3	0.6	1.7	1.9	1.4
Blood Red Count	0.7	6.5	33.4	-1.4	-1.1	-0.1	-3.8	-1.8	-3.4	-0.5	-1.4	-2.4	-1.6	-1.9	-0.8	0.1	3.0	3.4	5.8	-0.6	2.4	-5.3	1.2	-1.8	-1.7
Waist Hip Ratio (WHR)	0.7	3.2	8.3	1.3	0.4	-1.4	2.6	1.4	2.2	0.8	2.3	2.5	1.7	2.1	-2.2	2.0	-1.8	-0.8	-2.2	1.2	-0.8	2.9	0.2	1.8	1.3
Smoking Status	0.7	1.7	5.8	-0.5	-2.4	-1.8	1.3	-0.4	0.9	-0.5	1.6	1.5	0.3	0.4	-1.8	-0.5	-0.5	-2.1	-1.7	-0.3	-2.1	1.6	-1.5	0.1	-0.6
Allergy or Eczema	0.7	1.9	5.2	1.2	0.7	0.3	1.8	1.6	1.4	1.4	1.5	2.3	1.5	1.6	-0.4	2.1	-1.1	0.9	-0.5	1.3	0.7	1.0	1.2	1.4	1.8
Hypothyroidism (self reported)	0.7	1.5	3.5	1.3	1.9	1.2	1.0	1.4	1.3	1.6	-0.5	0.2	1.2	0.9	1.8	0.5	-1.0	1.6	-0.2	1.4	1.4	0.9	1.4	1.4	1.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	4.1	1.1	0.8	1.3	-0.5	1.0	0.1	0.8	2.0	1.2	0.2	0.9	-0.2	0.4	-0.3	0.8	0.2	0.8	1.0	-0.6	1.2	1.3	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	2.8	1.5	1.0	1.6	-0.2	1.1	-0.3	1.0	1.2	1.1	0.7	0.9	0.5	1.1	0.2	1.6	0.5	1.7	1.3	-0.4	1.0	1.0	1.0
Had menopause	0.7	0.9	3.5	1.1	0.3	0.6	-0.6	0.3	1.9	0.6	-0.1	1.8	1.0	1.2	0.9	0.9	-1.3	-0.3	-1.1	0.4	0.2	1.7	0.5	0.8	0.4
Had other major operations	0.7	0.9	3.8	-0.4	-1.8	-0.6	0.9	0.2	1.2	-0.1	-0.5	0.3	0.4	0.4	0.2	1.2	-1.1	-1.5	-1.4	0.1	-0.9	2.0	-0.6	0.5	0.2
Mouth/teeth dental problems	0.7	1.1	4.9	1.0	1.0	1.1	-1.3	0.3	-1.0	1.1	0.5	0.0	0.5	0.2	0.2	-0.2	0.6	1.5	1.6	0.8	1.6	-2.2	1.3	0.1	-0.1
Pain all over the body in last month	0.7	0.8	2.7	-0.5	-0.9	-0.3	-1.3	-1.2	-0.5	-0.7	-1.0	-1.4	-0.9	-1.1	0.6	0.1	0.9	0.1	1.6	-0.8	-0.4	-0.4	-0.7	-0.9	-0.8
Medication: Simvastatin	0.7	1.0	3.0	-1.3	-0.9	-0.6	-0.2	-0.7	-0.4	-1.7	-0.8	-0.7	-1.4	-0.7	-0.0	-1.5	1.1	-1.7	-0.5	-1.4	-1.1	0.0	-1.0	-0.7	-1.1
Arm fat percentage (right)	0.7	2.6	7.4	-1.4	-2.3	-0.3	-0.5	-1.5	0.7	-2.0	-2.3	-1.8	-1.2	-1.2	1.7	0.6	-0.2	-2.7	-1.4	-1.5	-1.9	2.1	-2.2	-1.3	-1.4
Alcohol intake versus 10 years previously	0.7	1.1	4.4	0.1	0.7	1.7	-1.4	-0.3	-1.3	-0.1	-0.6	-1.5	-0.4	-0.7	1.2	-0.1	0.6	1.4	2.1	-0.3	0.7	-1.8	0.5	0.4	-0.6
Illnesses of mother	0.7	0.8	3.7	0.9	0.6	1.3	0.6	0.9	0.4	1.3	-0.5	-0.2	0.8	0.6	1.4	1.9	-0.1	1.3	0.4	1.4	1.1	0.1	0.6	0.4	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.9	0.5	0.7	2.0	-1.9	-0.1	-1.5	0.0	0.4	-0.2	-0.2	-0.6	1.6	-0.1	0.2	1.3	1.7	0.5	1.0	-1.7	0.5	0.3	-0.5
Medication: Omeprazole	0.7	0.8	4.1	-1.1	-0.7	-0.2	-0.9	-0.9	-0.3	-0.7	-2.0	-0.5	-0.2	-1.2	0.6	-0.9	0.1	0.3	2.0	-0.6	-0.5	-0.1	-0.8	-0.3	-1.1
Arm fat percentage (left)	0.7	3.0	7.2	-1.7	-2.5	-0.4	-0.5	-1.7	0.5	-2.1	-2.7	-2.0	-1.4	-1.5	1.7	0.3	-0.2	-2.6	-1.3	-1.6	-1.9	1.9	-2.3	-1.5	-1.7
Financial situation satisfaction	0.7	0.9	2.5	-1.1	-0.4	-0.7	-0.1	-0.5	-0.4	-1.4	-0.2	-1.3	-1.2	-1.1	-0.6	-1.0	0.7	-1.6	0.8	-1.5	-1.2	0.1	-1.1	-0.7	-0.3
Ever smoked	0.7	1.3	5.0	0.1	-0.8	-0.2	1.4	0.4	2.2	0.3	-0.4	1.0	1.3	1.1	0.4	1.2	-2.0	-0.8	-1.5	1.0	-0.6	2.2	-0.5	1.1	0.3
Ever had prostate specific antigen (PSA) test	0.7	0.8	5.1	0.3	-0.5	-0.1	-0.2	0.2	-0.3	0.6	-0.9	-0.7	0.4	0.2	0.0	0.8	-0.3	2.3	1.7	1.3	1.3	-1.1	0.9	0.1	-0.1
Heart disease (siblings)	0.7	0.9	2.2	1.0	1.5	1.4	0.2	1.4	0.7	0.6	0.5	0.1	1.0	1.1	0.9	1.0	-0.7	0.7	-0.3	1.2	1.3	0.2	1.0	0.9	1.0
Leg fat mass (left)	0.7	2.8	9.0	-1.2	-2.4	-0.0	0.1	-1.1	1.0	-1.5	-2.9	-1.6	-0.8	-1.2	2.4	0.7	-0.4	-2.6	-1.4	-1.1	-1.9	3.0	-2.3	-0.8	-1.1
Bipolar Disorder (2018)	0.6	0.9	6.2	-0.6	-0.5	1.5	-1.4	-0.4	-0.2	-0.2	-2.1	-0.9	-0.4	-0.6	2.5	0.7	-0.7	0.3	0.4	0.5	0.7	-0.1	0.1	0.3	-0.5
Rheumatoid Arthritis	0.6	0.8	2.3	1.5	1.3	1.5	-0.4	0.8	0.2	1.0	0.3	0.1	0.5	0.6	1.5	0.9	0.4	1.0	-0.4	0.6	1.1	-0.2	1.1	0.5	0.6
Cardiovascular Disease	0.6	2.0	6.7	1.0	1.3	-0.1	0.8	1.4	2.6	0.5	1.5	1.8	1.7	2.4	-0.9	0.5	-0.2	-0.5	-1.7	0.6	0.4	2.1	1.4	1.6	2.1
Number of treatments/medications taken	0.6	1.1	5.0	-0.5	-1.1	-0.8	0.3	-0.3	0.8	-1.4	0.9	0.5	-0.4	-0.1	-0.2	-1.2	-0.4	-2.2	-2.1	-1.2	-1.6	1.5	-1.1	0.1	0.0
Severe depression (siblings)	0.6	0.7	2.1	-1.0	-1.3	-0.5	-0.4	-1.1	-0.3	-1.0	-1.0	-0.8	-0.8	-0.7	-0.1	-1.4	0.5	-0.3	-0.2	-1.2	-0.6	-0.4	-0.6	-0.6	-1.4
Qualifications: CSEs or equivalent	0.6	0.8	3.8	1.1	0.3	1.4	0.0	0.8	0.7	0.6	0.4	0.6	0.7	1.0	1.1	2.0	-0.7	0.2	0.6	0.8	0.5	0.4	0.9	1.7	0.9
Multivitamins +/- minerals	0.6	0.8	2.3	-1.5	-1.2	-1.3	-0.2	-1.2	0.1	-0.8	-0.8	-0.6	-0.9	-1.0	-0.4	-1.0	-0.1	-0.9	0.3	-1.0	-0.9	0.5	-1.2	-1.0	-1.0
Medication: Atenolol	0.6	0.8	3.8	-0.5	-0.5	-0.3	0.7	-0.2	1.1	-0.7	-1.8	0.0	-0.4	-0.4	1.0	-0.3	-0.9	-1.1	-1.0	-0.2	-0.9	2.0	-0.9	0.0	-0.3
Financial difficulties in last 2 years	0.6	0.8	1.5	-1.1	-0.9	-0.5	-0.5	-0.9	-1.0	-1.2	-0.0	-0.8	-1.2	-1.0	-0.4	-1.1	1.0	-1.0	0.5	-1.2	-1.2	-0.3	-1.2	-0.8	-1.0
Hayfever/allergic rhinitis (self-reported)	0.6	0.8	4.6	-0.1	0.2	-0.2	-0.4	-0.2	-1.9	0.0	-0.1	-0.3	-0.8	-0.8	-0.5	-1.2	0.5	1.4	0.9	0.1	0.6	-2.2	0.1	-1.2	-0.8
Happiness	0.6	0.7	3.3	-0.3	0.2	-1.4	0.7	-0.2	-0.3	-0.8	1.4	0.2	-0.5	-0.3	-1.8	-1.8	1.3	-0.5	0.0	-0.6	-1.2	0.4	-0.5	-0.4	0.2
Birth weight	0.6	1.2	4.3	-0.0	0.1	1.5	-1.3	0.4	-0.9	0.3	-1.8	-1.0	-0.2	-0.2	1.8	0.2	0.4	2.1	2.1	0.8	1.6	-1.2	0.9	0.1	0.1
Number of full brothers	0.6	0.7	3.7	-0.1	-1.3	1.1	0.2	0.2	0.8	0.0	-1.6	0.1	0.1	-0.2	1.9	0.3	-0.7	-1.3	-0.7	0.3	-0.4	1.5	-0.8	0.6	0.1
Angina (self-reported)	0.6	0.8	2.3	-0.5	-0.9	-1.1	1.2	-0.4	-0.0	-0.6	-0.2	0.4	-0.4	-0.7	-0.2	-0.9	0.7	-1.5	-1.1	-0.8	-1.5	1.3	-1.4	-0.9	-0.7
Family relationship satisfaction	0.6	0.8	5.8	0.9	0.7	-0.1	0.7	0.8	-0.2	0.5	2.4	1.5	0.5	0.6	-1.0	-0.3	1.2	-0.3	-0.6	-0.2	-0.3	0.5	0.4	0.4	1.4
Illnesses of siblings: Diabetes	0.6	0.8	4.0	-0.0	-0.1	-1.1	1.1	0.1	0.8	-0.5	1.1	0.3	0.0	0.4	-0.8	0.0	0.8	-2.0	-1.3	-1.1	-1.1	1.2	-0.8	-0.6	0.3
Illnesses of father: None of the above (group 1)	0.6	0.7	3.4	0.4	1.0	0.2	1.9	1.5	-0.5	0.8	1.2	1.0	0.6	0.5	-0.6	-0.1	0.8	0.3	-0.6	0.7	0.6	-0.2	0.5	0.1	1.5
Number of self-reported non-cancer illnesses	0.6	1.0	4.6	0.5	0.9	-0.4	1.1	1.1	1.7	-0.2	1.1	1.2	0.8	1.3	-0.5	0.7	-0.7	-0.9	-2.1	0.2	-0.2	1.3	0.4	0.9	1.0
Commuting to job workplace: Public transport	0.6	0.7	2.9	0.8	0.4	-0.2	-0.9	0.1	0.1	0.9	1.3	1.7	0.9	1.0	-1.7	0.2	-0.3	1.2	0.2	0.8	0.7	-0.4	0.8	0.1	0.5
Medication: Atorvastatin	0.6	0.7	1.9	0.9	1.1	-1.1	1.1	0.7	1.4	0.2	0.9	0.7	0.6	1.1	-1.0	0.4	0.2	0.1	-1.1	0.4	0.1	1.3	0.4	0.3	0.9
Commuting to job workplace: Cycle	0.6	0.7	3.3	-0.7	-1.1	-1.5	-0.0	-1.2	0.4	-1.0	0.4	0.5	-0.5	-0.2	-1.8	-0.4	0.2	-0.9	-0.5	-0.7	-1.2	0.6	-0.8	-1.0	-0.8
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	1.7	-1.3	-1.2	-0.9	-0.2	-0.9	-0.5	-0.9	-1.3	0.0	-0.2	-1.2	-0.5	-0.9	0.5	-0.2	1.3	-0.4	-1.1	0.2	-1.1	-0.5	-1.1
Basal cell carcinoma (self-reported)	0.6	0.7	3.4	-0.9	-0.8	-0.7	1.8	0.4	-0.6	-0.7	-0.7	-0.9	-0.5	-0.9	0.1	0.1	1.1	-1.3	-0.3	-1.0	-1.1	0.7	-0.9	-0.1	-0.2
Pack years of smoking	0.6	0.9	4.7	-1.0	-2.2	-1.3	0.2	-0.8	1.0	-0.6	-1.6	-0.0	0.4	-0.0	-0.6	0.3	-1.0	-0.8	-0.3	0.1	-1.0	1.5	-1.0	-0.4	-1.0
Alzheimer’s Disease (in mother)	0.5	0.6	1.4	-0.9	-1.0	-0.7	-0.9	-1.0	-0.9	-0.7	-0.3	-0.7	-1.0	-0.6	-1.0	0.3	0.9	0.2	0.9	-0.6	0.4	-1.2	0.1	-0.7	-0.6
Crohns Disease (2012)	0.5	0.7	2.2	-0.8	-0.1	-0.3	-0.4	-0.8	-1.5	-0.9	-0.6	-0.7	-1.4	-1.5	0.4	-0.6	-0.0	-0.7	-0.2	-1.4	-0.9	-0.4	-1.0	-1.1	-0.8
BMI	0.5	2.7	4.9	2.2	1.0	1.9	0.2	1.6	2.0	1.8	1.2	1.4	2.1	1.8	1.5	1.9	-1.8	0.4	-1.8	1.8	1.1	1.3	1.5	2.0	2.1
Lung FVC	0.5	2.4	7.6	-2.1	-1.4	-0.5	1.1	-0.9	-1.8	-1.5	-2.8	-2.0	-1.6	-2.5	0.1	-1.1	-0.5	-0.4	2.7	-1.4	-0.6	-1.7	-1.0	-0.6	-1.4
Chronotype (morning person)	0.5	1.1	3.3	1.8	1.3	1.3	0.5	1.4	0.2	1.2	1.3	0.6	1.0	0.8	0.8	0.4	0.6	0.9	0.7	0.5	1.1	-0.2	1.4	1.2	1.5
Angina	0.5	0.7	1.8	-0.5	-0.7	-1.2	1.1	-0.5	-0.2	-0.7	-0.1	0.4	-0.5	-0.7	-0.4	-0.9	0.8	-1.2	-0.8	-0.8	-1.4	0.9	-1.2	-1.0	-0.8
Medication for hormone replacement therapy	0.5	0.6	2.0	0.6	-0.2	0.9	-0.7	0.2	1.3	0.6	-1.3	0.6	0.6	0.5	1.4	0.6	-1.2	0.3	-0.7	0.6	0.4	0.8	0.3	0.6	-0.1
Diabetes (mother)	0.5	0.6	1.9	0.1	-1.2	0.3	0.4	0.8	1.3	-0.2	-0.2	0.1	0.7	0.9	-0.0	0.9	-1.4	-0.5	-1.0	0.6	-0.1	1.1	0.3	1.3	0.6
Hand grip strength (right)	0.5	1.4	4.2	-1.1	-1.0	0.1	-0.5	-0.6	-2.0	-0.2	-1.7	-2.0	-1.5	-1.8	0.9	-1.3	1.1	0.5	1.8	-1.0	0.1	-1.3	-0.4	-1.1	-0.9
Townsend deprivation index at recruitment	0.5	0.7	4.0	-1.0	-1.6	-0.0	-2.0	-1.3	-0.5	-0.1	-0.5	-0.6	-0.6	-0.7	0.0	-1.2	-0.4	-0.1	0.1	-0.8	-0.1	-0.9	-0.4	-0.5	-1.1
Hair/balding pattern: Pattern 3	0.5	0.7	4.7	0.7	2.2	0.2	1.1	0.3	1.1	0.1	0.8	0.5	0.9	0.5	1.1	-0.5	0.5	-0.5	-1.2	0.6	-0.2	1.2	-0.2	0.1	0.3
Standing height	0.5	4.7	14.0	2.6	2.4	2.3	-2.2	1.4	-1.4	2.5	2.5	0.7	1.3	1.4	0.5	0.6	0.5	3.7	2.6	1.4	3.1	-3.2	3.4	1.2	1.7
Medication: Ventolin 100micrograms inhaler	0.5	0.7	2.6	-0.4	-0.8	-1.3	0.3	-0.6	0.0	-0.8	0.6	1.2	-0.4	-0.1	-1.6	0.0	0.3	-1.1	-0.7	-0.8	-1.2	0.4	-1.0	-0.8	-0.7
Forced vital capacity (FVC), Best measure	0.5	1.7	12.2	-0.2	0.1	0.6	-0.7	-0.3	-2.6	0.1	-0.1	-0.5	-1.1	-1.2	-0.1	-0.9	1.5	1.0	3.5	-0.8	0.8	-3.1	0.5	-0.4	-0.4
Leg fat percentage (right)	0.5	1.8	13.0	0.2	-1.2	0.2	0.8	0.1	2.0	-0.5	-1.2	0.0	0.2	0.3	1.9	1.2	-0.9	-2.0	-2.4	0.0	-1.3	3.6	-1.2	0.3	0.0
Pulse rate, automated reading	0.5	1.7	6.8	1.0	1.7	2.0	0.4	2.0	0.2	1.1	-0.5	0.5	0.9	1.2	1.8	2.6	1.3	0.2	-1.2	1.2	1.7	0.5	1.2	0.7	1.7
Diabetes diagnosed by doctor	0.5	0.7	2.3	-0.9	-0.9	-0.9	-0.1	-0.9	-0.2	-1.5	-0.4	-0.2	-1.2	-1.0	-0.2	-0.4	0.4	-1.3	0.2	-1.4	-1.2	0.3	-1.1	-1.0	-0.7
Eye problems/disorders: Cataract	0.5	0.6	2.8	0.7	-0.0	1.1	-1.7	0.4	-0.9	0.3	0.7	0.3	-0.2	0.4	0.1	0.8	0.1	0.8	-0.3	-0.0	1.3	-1.4	1.2	-0.2	0.9
Breast cancer (self-reported)	0.5	0.5	1.5	0.8	0.8	1.2	0.7	0.9	0.9	0.3	-0.2	0.4	0.6	0.7	1.2	1.0	0.2	-0.0	-1.1	0.7	0.2	0.6	0.3	0.9	0.6
Ever taken oral contraceptive pill	0.5	0.5	1.3	1.0	0.6	0.2	0.9	0.9	0.8	0.4	0.8	0.2	0.7	0.9	0.2	1.1	-0.9	0.2	-0.1	1.1	0.3	0.9	0.5	0.6	0.7
Illnesses of father: High blood pressure	0.5	0.6	2.9	-0.5	-0.6	0.1	-1.2	-1.0	0.6	-0.7	-1.6	-0.9	-0.3	-0.5	1.2	-0.3	-1.7	-0.4	-0.1	-0.4	-0.5	0.7	-0.4	0.3	-0.6
Alcohol drinker status: Never	0.5	0.6	5.9	0.7	2.4	0.1	0.3	0.5	1.0	0.4	0.9	0.5	0.6	0.4	0.1	-0.4	0.7	-0.3	-0.4	0.2	-0.1	0.9	0.4	0.9	0.7
Alzheimer’s Disease (in father)	0.4	0.4	1.8	0.3	0.4	-0.6	0.4	0.4	-0.0	-0.2	1.3	1.2	-0.3	0.4	-1.1	-0.6	0.8	-0.7	-1.1	-0.4	-0.4	0.7	0.0	0.4	0.5
Alzheimer’s Disease (including proxy)	0.4	0.6	4.1	-0.5	-1.0	-1.2	-0.5	-0.4	-0.6	-0.9	1.1	0.4	-0.8	0.2	-2.0	-0.2	1.3	-0.5	-0.4	-0.6	0.0	-0.7	0.2	-0.3	-0.3
Breast Cancer	0.4	1.0	4.9	0.3	-0.7	-0.5	1.2	0.6	1.6	0.5	-0.9	1.1	0.7	0.7	0.1	0.9	-1.5	-1.3	-1.3	0.6	-0.8	2.2	-0.5	0.9	0.6
LDL Cholesterol	0.4	0.7	3.0	0.6	-0.5	-0.9	1.3	0.1	0.1	-0.4	1.4	1.7	-0.1	0.4	-1.4	0.3	0.7	-0.8	-1.0	-0.1	-1.2	0.8	-0.8	-0.1	0.1
Height	0.4	7.5	28.6	-1.6	-0.3	1.1	-3.9	-2.4	-4.0	-1.2	-2.6	-3.8	-2.4	-2.7	1.3	-1.5	3.4	2.0	5.3	-1.5	1.4	-4.7	-0.1	-3.0	-2.2
Hand grip strength (left)	0.4	1.1	3.8	-1.1	-1.2	0.6	-0.3	-0.2	-1.4	-0.2	-1.8	-1.9	-1.3	-1.5	1.1	-0.9	1.1	0.1	2.0	-0.7	0.1	-0.9	-0.2	-0.4	-0.4
Relative age voice broke	0.4	0.6	2.8	-0.1	-0.9	-1.1	1.7	-0.1	-0.6	-0.4	1.5	0.1	-0.2	-0.2	-1.6	0.3	-0.5	-0.7	-0.7	-0.2	-0.9	0.4	-0.7	-0.4	-0.0
Taking other prescription medications	0.4	0.6	2.3	1.0	1.5	1.0	0.4	1.0	0.5	0.2	0.5	1.1	0.6	0.7	1.2	0.7	-0.0	0.0	-1.5	0.2	0.4	0.6	0.5	0.5	0.6
Forced vital capacity (FVC)	0.4	1.4	8.4	0.8	0.4	1.3	-0.5	0.6	-1.5	1.4	0.5	0.4	0.5	-0.0	0.5	0.2	0.6	1.7	2.9	0.3	1.5	-2.4	1.5	0.7	0.5
Medication: Cholesterol lowering	0.4	0.6	3.9	-0.5	0.5	-0.5	-0.1	-0.5	-0.5	-1.2	0.1	-0.9	-0.8	-0.6	-0.1	-0.8	2.0	-0.7	-0.1	-1.1	-0.6	-0.2	-0.5	-0.8	-0.4
Prospective memory result	0.4	0.5	2.6	-0.4	0.0	-0.5	0.1	-0.8	-0.6	-0.8	0.2	0.1	-0.5	-0.6	-0.1	-0.6	1.6	-0.8	-0.0	-1.1	-1.1	0.3	-0.9	-0.6	-0.5
Exposure to tobacco smoke at home	0.4	0.5	2.0	-0.9	-1.3	-0.5	-1.4	-1.0	0.5	-0.6	-0.5	-0.1	-0.3	-0.0	-0.8	-0.4	-1.3	-0.3	0.0	-0.5	-0.6	-0.3	-0.2	-0.1	-0.8
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	2.9	-0.5	0.1	0.8	-1.7	-0.7	-0.6	-0.5	-0.5	-0.4	-0.8	-0.8	0.9	-0.5	0.1	0.4	1.0	0.1	0.7	-1.0	-0.1	-0.6	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	3.5	0.7	0.3	0.4	0.2	0.7	-0.6	0.5	1.9	0.4	0.3	0.7	-0.1	-0.1	0.7	0.7	0.6	-0.1	0.4	-0.8	0.9	0.6	0.8
Whole body fat mass	0.4	1.7	6.1	-0.6	-2.0	0.6	-0.4	-0.8	0.8	-1.0	-2.1	-1.3	-0.5	-0.8	2.5	0.9	-0.3	-1.9	-1.3	-0.9	-1.2	2.2	-1.5	-0.6	-0.8
Had major operations	0.4	0.5	2.7	0.4	-0.6	-0.2	0.8	0.5	0.8	-0.1	0.9	1.1	0.2	0.7	-0.5	0.4	-0.2	-1.2	-1.6	0.0	-0.6	1.0	-0.2	0.6	0.3
Commuting to job workplace: Car/motor vehicle	0.4	0.4	3.6	0.3	0.3	0.7	-0.2	-0.2	-0.1	0.2	-1.5	-0.3	-0.1	-0.3	1.9	0.6	0.1	0.7	1.0	0.4	0.6	-0.1	-0.1	-0.2	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	2.3	0.4	-0.2	0.8	-0.4	0.3	0.9	0.3	-0.6	1.0	0.9	0.3	0.8	0.8	-1.1	0.1	0.2	0.8	0.1	1.0	0.4	1.5	0.4
Loneliness, isolation	0.4	0.5	1.7	-0.1	0.6	1.1	-1.1	0.0	-1.2	-0.2	1.0	-0.4	-0.6	-0.3	0.2	-0.8	1.1	0.4	0.7	-0.0	0.4	-1.3	0.4	0.4	0.3
Long-standing illness, disability or infirmity	0.4	0.6	4.0	1.0	1.3	0.9	0.3	0.2	0.9	-0.7	0.4	0.5	0.0	0.6	1.3	-0.1	-0.9	-0.9	-2.0	-0.5	-0.5	0.7	-0.1	0.2	-0.1
Commuting to job workplace: Walk	0.4	0.4	3.0	0.5	-0.3	0.3	-0.4	0.2	0.7	0.3	0.8	0.8	0.5	0.6	-0.2	-0.3	-1.2	-0.4	-1.7	0.3	-0.2	0.8	0.1	0.4	0.6
Medication: Paracetamol	0.4	0.6	2.5	0.2	-1.4	-0.6	-0.5	-0.2	0.6	0.6	1.6	1.4	0.6	0.5	-0.6	-0.9	-1.4	-0.3	-0.8	0.1	-0.6	0.6	-0.2	0.5	-0.1
Leg fat percentage (left)	0.4	1.6	11.3	-0.0	-1.1	0.2	0.9	0.1	1.8	-0.5	-1.3	-0.2	0.1	0.1	1.8	1.3	-0.6	-1.9	-2.1	-0.1	-1.2	3.4	-1.3	0.1	0.1
Myopia	0.4	0.5	2.3	0.9	1.2	0.3	-0.5	0.2	0.3	0.7	1.5	0.6	0.5	1.0	-0.1	0.8	0.4	0.4	0.3	-0.2	0.9	-0.5	1.2	0.3	0.6
Major Depression (MDD)	0.3	0.4	1.4	-0.8	-1.2	0.6	0.2	0.4	-0.9	-0.0	-0.8	-1.0	-0.6	-0.6	0.5	-0.6	0.1	0.2	1.0	-0.0	0.4	-1.1	0.1	0.3	0.2
Reaction Time	0.3	0.6	2.6	0.5	1.3	1.1	-0.2	0.9	-0.3	1.1	-0.5	0.5	0.2	0.2	1.0	0.3	-0.9	1.0	-0.2	0.6	1.6	-1.1	0.9	0.0	0.1
Age at First Birth	0.3	0.4	2.0	0.2	1.2	0.3	-0.4	0.2	-0.9	0.4	0.4	-0.0	0.2	-0.0	-0.5	-0.6	0.0	1.0	0.7	0.2	0.7	-1.4	0.7	-0.4	0.3
HDL Cholesterol	0.3	0.5	2.3	0.1	-0.5	-0.7	0.8	0.1	0.6	0.1	1.5	1.1	0.2	0.5	-0.4	-1.0	0.1	-0.8	-1.2	-0.2	-0.7	1.1	-0.5	-0.2	0.6
Systolic Blood Pressure	0.3	1.3	10.0	-1.2	-0.6	-1.8	0.1	-0.9	0.7	-1.1	0.2	-0.5	-0.6	-0.1	-1.0	-3.2	-1.1	-1.5	-0.5	-1.7	-1.1	0.5	-0.6	-0.4	-0.6
Respiratory disease	0.3	0.6	4.8	0.8	0.9	-0.1	-0.6	0.1	0.6	0.1	0.8	2.2	0.2	0.7	-0.5	1.2	-0.4	0.8	-0.8	0.7	0.7	-0.1	0.3	-0.5	0.1
Medication: Metformin	0.3	0.4	1.8	0.1	-0.1	0.2	1.1	0.5	1.0	-0.6	-1.0	0.4	-0.1	0.1	1.1	0.5	-0.1	-1.0	-0.3	-0.6	-0.5	1.4	-0.5	-0.1	0.3
Trunk fat percentage	0.3	1.0	5.5	1.1	-0.3	1.5	-0.6	0.5	1.3	0.3	-0.3	-0.2	0.6	0.8	2.3	2.2	-0.4	-0.4	-1.3	0.4	0.4	1.5	0.3	0.5	0.6
Number of incorrect matches in round	0.3	0.5	4.5	0.4	2.1	-0.2	0.6	0.8	0.5	-0.0	0.5	0.3	0.4	0.6	-0.3	-0.2	-1.0	0.5	-0.8	0.5	0.5	0.1	0.6	0.8	0.6
Hearing difficulty/problems with background noise	0.3	0.5	2.3	0.9	0.5	0.7	-0.5	0.5	0.3	0.6	1.5	0.8	1.0	0.8	0.1	0.3	-0.2	0.1	-0.9	0.5	0.7	-0.4	0.7	0.3	0.7
Allergy	0.3	0.8	2.5	1.1	0.9	1.2	-1.0	0.7	-0.2	1.0	0.4	-0.3	0.7	0.6	0.9	-0.4	-0.2	1.0	0.8	0.8	1.6	-1.1	1.5	0.9	0.7
Diabetes (self-reported)	0.3	0.4	2.3	-0.3	-0.3	-0.3	0.2	-0.2	0.5	-1.1	-0.3	0.3	-0.7	-0.4	0.3	-0.3	-0.4	-1.5	-0.7	-1.1	-0.9	0.9	-0.7	-0.3	-0.1
Illnesses of siblings	0.3	0.4	2.3	0.3	0.6	-0.1	0.4	0.1	0.1	1.1	-0.6	0.5	0.5	0.0	-0.0	0.3	-0.2	1.4	0.9	1.5	0.6	-0.0	0.2	0.2	-0.0
Number of live births	0.3	0.4	1.5	-0.4	-1.2	0.1	-1.0	-0.8	-0.5	0.0	-1.0	-1.0	-0.4	-0.7	1.1	-0.8	-0.1	0.5	0.4	-0.1	0.1	-0.1	-0.3	-0.0	-0.6
Asthma	0.3	0.6	3.5	-0.5	-0.2	0.4	-1.2	-0.8	0.4	-0.6	-1.9	0.2	-0.8	-0.4	1.2	1.1	-0.7	-0.1	-0.2	-0.2	-0.2	0.2	-0.6	-0.7	-1.2
Loud music exposure frequency	0.3	0.4	2.3	-0.5	-0.6	0.9	-0.5	-0.4	-0.7	-0.0	-1.3	-0.8	-0.3	-0.5	1.5	-0.3	-0.4	0.4	0.3	0.0	0.2	-0.2	-0.3	0.2	-0.5
High blood pressure (siblings)	0.3	0.4	2.0	-0.7	-0.8	-0.2	-1.1	-0.7	-0.3	-0.9	-0.0	-0.5	-0.7	-0.4	0.2	-1.0	-0.2	-0.9	-0.4	-1.4	-0.6	-0.1	-0.4	-0.4	-0.4
Body fat percentage	0.3	1.0	5.0	0.3	-1.0	0.8	-0.3	-0.1	1.4	-0.5	-0.9	-0.4	0.1	0.2	2.1	1.6	-0.4	-1.3	-1.7	-0.1	-0.6	2.2	-0.6	0.0	-0.0
Shortness of breath walking on level ground	0.3	0.4	1.6	0.5	1.0	-0.2	0.1	0.2	0.8	-0.0	0.8	1.3	-0.0	0.6	-0.2	0.2	-0.9	-0.7	-0.9	-0.2	-0.5	1.1	-0.3	-0.0	0.7
Medication: Seretide 50 evohaler	0.3	0.4	1.9	-0.1	-0.4	-0.9	0.8	-0.0	0.1	-0.3	0.5	1.0	0.0	0.2	-0.5	0.5	0.1	-0.8	-1.4	-0.1	-1.1	0.9	-0.7	-0.2	0.3
Chest pain or discomfort	0.3	0.4	2.2	-0.2	-1.5	-0.9	0.9	0.4	-0.5	-0.1	1.1	0.3	0.0	-0.2	-1.0	-0.8	0.4	-0.3	-0.3	0.1	-0.2	-0.2	-0.4	-0.5	0.6
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	4.0	-0.2	0.6	-0.2	0.1	-0.3	0.2	0.3	-2.0	-0.5	0.3	-0.4	0.7	0.0	-1.2	0.7	0.1	0.1	0.4	0.5	-0.1	-0.4	-0.3
Average weekly red wine intake	0.3	0.5	1.2	-1.0	-0.5	-1.0	0.5	-0.7	-0.4	-1.1	-0.2	-0.7	-0.6	-0.5	-1.0	-0.4	0.4	-0.7	0.1	-0.6	-0.9	0.1	-0.9	-0.7	-0.7
Qualifications: nursing, teaching	0.3	0.4	1.9	0.4	-0.6	0.1	0.4	0.4	-1.0	0.9	-0.0	0.3	0.4	-0.1	-0.4	0.8	0.5	1.4	0.8	0.7	0.9	-1.0	0.4	-0.3	0.1
Asthma (self-reported)	0.3	0.7	2.3	-0.8	-0.6	-0.2	-1.1	-1.2	0.4	-1.1	-1.5	0.4	-1.0	-0.6	0.6	0.7	-0.5	-0.6	-0.5	-0.5	-0.7	0.4	-1.0	-0.9	-1.4
Average weekly champagne plus white wine intake	0.3	0.4	1.4	0.3	0.3	-0.7	1.2	0.5	0.9	0.1	0.2	0.5	0.5	0.5	-1.0	0.8	-0.7	0.3	-0.1	0.4	0.3	0.8	0.4	0.0	0.8
High cholesterol (Self-reported)	0.3	0.5	2.1	-0.3	0.0	-1.2	1.1	0.1	0.6	-0.8	-0.1	-0.1	-0.1	0.4	-1.1	-0.9	1.4	-0.8	-1.1	-0.2	-0.5	1.1	-0.4	-0.3	0.2
Fractured/broken bones in last 5 years	0.3	0.4	1.5	0.7	1.0	0.6	-0.3	0.3	1.2	0.6	0.1	0.1	1.2	0.8	0.5	-0.0	-0.4	-0.5	-0.1	0.6	0.4	0.4	0.4	0.8	0.1
Ever depressed for a whole week	0.3	0.4	1.3	0.7	1.1	0.7	-0.0	0.6	-0.0	0.5	1.1	0.7	0.3	0.3	0.5	-1.2	0.3	0.7	-0.0	0.1	0.6	-0.5	0.7	0.9	0.8
Ovarian Cancer	0.2	0.2	1.3	0.0	0.5	-0.2	-1.0	-0.5	0.4	0.1	-0.5	0.0	0.3	-0.1	0.1	-0.3	-1.2	0.3	-1.0	0.3	-0.0	0.0	-0.1	-0.0	-0.5
Blood Platelet Count	0.2	2.0	11.2	1.6	2.0	0.6	1.2	1.9	0.3	0.4	1.0	1.7	0.8	1.4	-0.3	3.3	1.2	1.2	1.1	0.6	1.6	-0.4	1.9	0.6	1.7
Lung FEV1/FVC ratio	0.2	1.2	4.6	-1.0	-1.0	-0.6	0.8	-0.2	-1.2	-1.2	1.2	-2.2	-0.8	-1.1	-0.9	-0.3	1.7	-1.5	1.4	-1.3	-1.7	-0.0	-0.8	0.7	0.1
Tanning	0.2	2.2	4.8	-1.7	-1.2	-1.9	1.2	-1.0	-1.9	-1.6	-0.2	-0.4	-2.1	-1.6	-1.8	-1.5	1.8	-1.6	0.8	-2.2	-1.5	-1.3	-1.3	-1.3	-1.1
Hearing difficulty/problems: Yes	0.2	0.3	1.0	0.0	-0.3	0.6	-0.8	-0.4	-0.4	-0.3	0.3	-0.8	-0.1	-0.2	0.4	-0.7	-0.3	-0.7	-1.0	-0.7	-0.2	-0.5	-0.2	-0.2	-0.4
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	1.2	-0.1	0.2	0.3	-0.8	-0.4	-0.3	-0.7	0.2	0.4	-0.5	-0.5	0.8	-0.2	0.6	-0.5	-0.4	-0.4	-0.0	-0.3	-0.5	-1.1	-0.7
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.7	-0.2	-0.2	-0.8	1.1	0.1	0.4	-0.3	1.0	0.9	-0.2	0.2	-1.3	0.9	-0.1	-0.4	-0.4	-0.4	-0.8	0.7	-0.4	-0.3	0.2
Trunk fat mass	0.2	1.0	6.4	0.0	-1.2	1.1	-0.8	-0.3	0.7	-0.5	-1.5	-1.2	-0.2	-0.3	2.5	1.4	-0.2	-1.1	-0.9	-0.5	-0.4	1.5	-0.7	-0.3	-0.3
Waist circumference	0.2	0.9	5.0	0.4	-0.8	0.7	0.4	0.1	1.3	-0.2	-0.4	-0.1	0.4	0.3	1.6	1.2	-0.8	-1.4	-1.7	-0.1	-0.9	2.2	-0.7	0.5	0.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.9	0.3	0.9	0.8	0.9	0.9	-0.2	-0.1	0.6	0.2	-0.1	0.1	0.6	0.2	0.3	0.2	0.1	-0.2	0.2	-0.2	0.5	0.8	0.9
Falls in the last year	0.2	0.3	1.1	-0.4	0.1	-0.6	-0.3	-0.4	-0.3	0.1	-0.1	0.3	-0.3	-0.5	-0.3	-1.1	0.1	-0.7	-0.7	-0.9	-0.6	0.3	-0.7	-0.9	-0.6
Noisy workplace	0.2	0.3	1.4	-0.1	-1.1	1.0	-0.9	-0.4	-0.3	0.1	0.5	0.4	-0.0	-0.1	0.8	-1.2	-0.0	-0.7	-0.2	-0.3	-0.2	0.1	-0.2	0.3	0.2
Medication: Lansoprazole	0.2	0.2	1.2	0.2	-0.7	0.2	-1.1	-0.3	-0.5	0.1	0.5	0.1	0.1	-0.1	-0.5	0.7	0.2	0.2	0.2	0.3	0.2	-0.5	0.3	0.3	-0.1
Glaucoma (self-reported)	0.2	0.3	1.3	-1.1	-0.0	-0.6	0.1	-0.3	-0.1	-1.0	-1.1	-0.2	-0.4	-0.5	-0.2	0.1	-0.5	-0.2	-0.4	-0.1	-0.1	0.2	-0.5	-0.8	-0.2
Gout (self-reported)	0.2	0.3	1.6	0.1	0.2	0.2	-0.8	-0.2	-0.3	-0.4	-0.5	-0.4	-0.5	-0.1	0.6	-0.3	1.3	0.4	1.1	-0.5	0.4	-0.8	0.1	-0.5	-0.4
Exposure to tobacco smoke outside home	0.2	0.2	0.6	0.1	-0.5	0.2	-0.3	0.4	0.0	0.5	0.7	0.7	0.3	0.3	-0.3	0.0	0.2	0.8	0.6	0.4	0.6	-0.5	0.6	0.8	0.4
Migraine (self-reported)	0.2	0.2	1.0	0.7	0.7	0.4	0.1	0.3	0.2	-0.2	1.0	0.7	0.0	0.3	-0.3	0.4	0.2	-0.5	-0.7	-0.3	-0.1	-0.0	0.2	0.1	0.5
Medication: Allopurinol	0.2	0.2	1.6	0.1	0.3	0.7	-0.0	0.1	0.3	-0.4	-0.6	0.4	-0.4	0.0	1.3	0.1	0.8	-0.3	0.3	-0.6	-0.4	0.7	-0.4	0.1	0.2
Alcohol intake frequency.	0.2	0.4	1.8	0.3	1.2	1.0	-1.1	-0.3	0.3	-0.4	-0.5	-0.6	-0.5	-0.3	1.3	-1.2	0.6	-0.1	-0.2	-0.5	-0.1	0.3	-0.2	0.6	-0.4
Knee pain experienced in last month	0.2	0.3	1.2	-0.5	-0.8	0.2	-0.6	-0.4	-0.2	-0.3	-0.7	0.1	-0.2	-0.7	1.1	-0.5	0.0	-0.5	-0.5	-0.2	-0.6	0.2	-0.9	-0.6	-0.7
Illnesses of father: Heart disease	0.2	0.2	1.0	-0.2	-0.2	-0.3	-0.8	-0.9	-0.4	-0.6	0.3	0.0	-0.4	-0.4	-0.3	-0.1	-0.3	0.2	0.5	-0.5	-0.2	-0.8	-0.2	-0.3	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	1.8	0.2	-0.3	-0.2	-1.0	-0.2	-0.4	0.1	1.1	-0.4	-0.0	-0.2	-0.7	-0.6	0.1	0.4	1.3	-0.3	-0.1	-0.9	0.3	0.4	-0.3
Ever had bowel cancer screening	0.2	0.3	1.8	0.6	0.7	0.3	-0.6	0.0	-0.2	0.5	0.3	-0.1	0.6	0.2	0.0	0.2	-0.1	1.3	0.7	0.6	0.7	-0.8	0.7	0.0	-0.1
Hearing aid user	0.2	0.2	1.7	-0.2	-0.2	-0.5	0.4	0.1	0.6	-0.1	0.4	0.5	-0.0	-0.0	-0.6	-1.3	-0.2	-0.3	-0.5	-0.2	-0.4	0.5	-0.2	0.1	0.3
Alcohol drinker status: Previous	0.2	0.2	0.8	0.0	0.3	0.9	-0.3	0.4	-0.6	-0.3	-0.1	-0.6	-0.4	-0.4	0.9	-0.5	0.0	0.1	-0.0	-0.3	0.5	-0.6	0.1	0.1	-0.1
Depressed Affect (Nagel 2018)	0.1	0.2	1.2	0.7	0.3	-0.1	0.8	0.5	0.1	-0.1	1.1	0.7	0.0	0.6	-0.4	-0.5	0.7	-0.2	-0.2	0.5	-0.2	0.5	-0.1	0.5	0.4
Neuroticism (Nagel 2018)	0.1	0.2	1.0	0.5	0.4	-0.2	-0.0	-0.1	-0.2	-0.4	0.7	0.6	-0.0	0.3	-0.3	-0.6	1.0	-0.1	0.5	0.5	-0.1	-0.1	-0.3	-0.1	-0.4
Worry (Nagel 2018)	0.1	0.2	0.5	0.5	0.6	0.1	-0.1	0.2	0.3	-0.1	0.5	0.4	0.3	0.5	-0.1	0.6	0.7	0.1	0.7	0.7	0.0	-0.0	0.2	0.3	0.1
Blood Eosinophil Count	0.1	1.0	3.3	1.1	1.4	1.8	-1.4	0.3	1.2	0.9	-0.5	0.4	1.0	0.7	1.7	1.6	-1.0	0.7	0.2	0.7	0.8	0.1	0.9	1.1	0.3
Blood White Count	0.1	0.5	1.9	-0.2	-0.5	1.0	-1.4	-0.1	0.0	-0.7	-1.0	-0.3	-0.4	-0.0	0.6	1.2	0.9	0.1	0.8	0.4	0.6	-0.9	0.5	0.7	-0.6
Type 2 Diabetes (T2D) (2018)	0.1	0.3	1.1	-0.0	0.6	-0.2	-0.7	-0.3	-0.3	-0.7	0.7	0.2	-0.8	-0.3	-0.1	-0.3	1.1	-0.6	0.3	-1.0	-0.3	-0.5	-0.1	-0.5	0.0
Hair Pigment	0.1	2.9	8.9	-2.4	-0.8	1.1	-1.4	-1.1	-2.6	-0.9	-2.7	-3.0	-1.4	-2.3	1.9	-1.1	0.8	1.1	2.7	0.1	-0.0	-2.0	-1.0	-0.4	-1.8
Relative age of first facial hair	0.1	0.3	0.8	-0.0	-0.5	0.2	-0.8	-0.6	-0.8	-0.6	0.7	-0.6	-0.7	-0.6	-0.4	0.2	-0.7	-0.2	0.2	-0.8	-0.2	-0.9	-0.0	-0.5	-0.4
Qualifications: College or University degree	0.1	0.5	1.7	0.3	-0.3	0.6	0.6	0.5	-0.3	0.8	0.0	0.3	0.9	0.3	-0.4	0.8	-1.3	1.3	1.0	1.0	0.6	-0.7	0.6	0.3	0.0
Mean time to correctly identify matches	0.1	0.2	0.9	-0.3	1.0	0.1	0.2	0.1	-0.3	-0.0	-0.5	0.3	-0.4	-0.4	0.3	-0.2	-0.0	-0.3	-0.7	-0.5	0.5	-0.5	-0.1	-0.7	-0.3
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.7	0.1	-0.2	-0.0	-0.2	-0.0	-0.4	0.1	-0.1	0.2	-0.1	-0.2	0.4	-0.1	0.9	0.1	0.3	-0.1	-0.0	-0.4	-0.1	-0.3	-0.2
Heel T-Score	0.0	0.3	1.6	-0.5	0.0	-0.5	-0.1	-0.4	-0.8	-0.6	-0.1	0.3	-0.5	-0.2	-1.3	0.4	-0.0	0.5	0.6	-0.2	0.2	-1.2	0.4	-0.1	-0.4
Heart attack	0.0	0.1	0.5	0.2	-0.2	-0.1	0.0	0.1	-0.4	0.2	0.1	0.2	-0.1	-0.1	0.3	-0.0	0.7	0.2	0.2	-0.1	0.0	-0.4	-0.0	-0.4	-0.1
Hair/balding pattern: Pattern 4	0.0	0.1	0.5	0.1	-0.5	0.1	-0.2	0.2	-0.4	0.2	-0.1	-0.1	-0.1	0.2	-0.3	0.1	0.5	0.3	0.2	0.1	-0.0	-0.7	0.2	0.2	-0.0

Hub : Genes

CTSB

Models

Trait associations