TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Blood Red Count
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chr8:25,544,268-28,325,411
Best TWAS P=1.48e-08 · Best GWAS P=4.2e-14 conditioned to 8.5e-13
25.5M
26M
26.5M
27M
27.5M
28M
0
5
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Pancreas
CCDC25
0.26
0.19
enet
36
0.14
1.3e-06
5.0
-5.7
1.5e-08
-0.11
0.01
0.99
TRUE
2
GTEx
Heart Atrial Appendage
SDAD1P1
0.21
0.14
lasso
5
0.12
3.7e-06
4.8
-5.2
2.2e-07
0.26
0.97
0.00
TRUE
1
CommonMind
Brain Pre-frontal Cortex
CCDC25
0.18
0.09
bslmm
659
0.13
3.1e-15
5.0
5.5
3.2e-08
0.05
0.01
0.98
FALSE
4
The Cancer Genome Atlas
Pheochromocytoma and Paraganglioma
CCDC25
0.16
0.12
blup
80
0.13
5.9e-06
4.4
5.3
9.6e-08
0.05
0.01
0.98
FALSE
5
The Cancer Genome Atlas
Soft Tissue Sarcoma
CCDC25
0.06
0.00
blup
81
0.04
3.2e-03
-3.8
5.3
1.0e-07
0.10
0.01
0.34
FALSE