Best TWAS P=1.48e-08 · Best GWAS P=4.2e-14 conditioned to 8.5e-13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CCDC25 | 0.18 | 0.09 | bslmm | 659 | 0.13 | 3.1e-15 | 5.0 | 5.5 | 3.2e-08 | 0.05 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | SDAD1P1 | 0.21 | 0.14 | lasso | 5 | 0.12 | 3.7e-06 | 4.8 | -5.2 | 2.2e-07 | 0.26 | 0.97 | 0.00 | TRUE |
| 3 | GTEx | Pancreas | CCDC25 | 0.26 | 0.19 | enet | 36 | 0.14 | 1.3e-06 | 5.0 | -5.7 | 1.5e-08 | -0.11 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CCDC25 | 0.16 | 0.12 | blup | 80 | 0.13 | 5.9e-06 | 4.4 | 5.3 | 9.6e-08 | 0.05 | 0.01 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | CCDC25 | 0.06 | 0.00 | blup | 81 | 0.04 | 3.2e-03 | -3.8 | 5.3 | 1.0e-07 | 0.10 | 0.01 | 0.34 | FALSE |