Best TWAS P=9.13e-13 · Best GWAS P=1.26e-14 conditioned to 0.000253
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | GNG12 | 0.19 | 0.16 | lasso | 5 | 0.14 | 5.0e-11 | -5.4 | -5.4 | 6.1e-08 | -0.29 | 1.00 | 0.00 | FALSE |
| 2 | METSIM | Adipose | GADD45A | 0.05 | 0.03 | enet | 35 | 0.02 | 1.1e-04 | 2.4 | -5.3 | 1.4e-07 | -0.07 | 0.47 | 0.02 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | GNG12 | 0.05 | 0.02 | lasso | 4 | 0.04 | 3.1e-05 | -5.4 | -7.1 | 9.1e-13 | -0.64 | 0.12 | 0.86 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | GNG12 | 0.04 | 0.03 | enet | 9 | 0.04 | 1.0e-04 | 6.4 | -6.3 | 3.0e-10 | -0.79 | 0.15 | 0.78 | FALSE |