Best TWAS P=3.76e-32 · Best GWAS P=7.5e-35 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NANS | 0.08 | 0.09 | lasso | 3 | 0.08 | 2.4e-10 | 6.3 | 6.2 | 5.3e-10 | 0.50 | 1.00 | 0.00 | FALSE |
| 2 | CommonMind | Brain Pre-frontal Cortex | TRIM14 | 0.10 | 0.02 | enet | 22 | 0.05 | 5.3e-07 | 10.6 | -7.6 | 4.2e-14 | -0.54 | 0.30 | 0.33 | FALSE |
| 3 | GTEx | Adipose Subcutaneous | TRIM14 | 0.11 | 0.05 | enet | 13 | 0.02 | 6.1e-03 | 6.3 | -7.6 | 2.7e-14 | -0.53 | 0.74 | 0.02 | FALSE |
| 4 | GTEx | Breast Mammary Tissue (Female) | C9orf156 | 0.42 | 0.22 | lasso | 10 | 0.23 | 1.5e-07 | 3.0 | 8.0 | 1.5e-15 | 0.71 | 0.05 | 0.89 | FALSE |
| 5 | GTEx | Cells Transformed fibroblasts | NANS | 0.41 | 0.26 | enet | 20 | 0.28 | 2.6e-21 | -5.0 | -5.7 | 9.7e-09 | -0.39 | 1.00 | 0.00 | FALSE |
| 6 | GTEx | Ovary | C9orf156 | 0.39 | 0.23 | enet | 15 | 0.18 | 3.9e-05 | 3.0 | 6.0 | 2.1e-09 | 0.55 | 0.22 | 0.24 | FALSE |
| 7 | GTEx | Testis | NANS | 0.38 | 0.15 | enet | 51 | 0.15 | 3.3e-07 | 10.9 | 9.0 | 2.4e-19 | 0.67 | 0.20 | 0.79 | FALSE |
| 8 | METSIM | Adipose | ANP32B | 0.05 | 0.03 | lasso | 6 | 0.02 | 1.1e-03 | 12.3 | -11.8 | 3.8e-32 | -0.97 | 0.00 | 1.00 | TRUE |
| 9 | YFS | Blood | ANP32B | 0.03 | 0.02 | lasso | 9 | 0.02 | 1.9e-08 | 12.3 | -10.3 | 7.1e-25 | -0.86 | 0.00 | 1.00 | FALSE |