TWAS hub - ANP32B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.0453	0.0176	3.4e-03	0.030	0.011	0.011	0.011	0.017	2.5e-05	8.6e-03	6.9e-03	7.4e-03	1.1e-03
2	YFS	Blood	0.0293	0.0098	9.6e-06	0.016	0.019	0.020	0.021	0.024	2.8e-06	3.7e-07	2.5e-07	1.7e-07	1.9e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Medication: Levothyroxine sodium	25.7	43.5	78.9	-2.8	-8.9
Hypothyroidism/myxoedema (self-reported)	23.0	44.8	84.6	-2.2	-9.2
Hypothyroidism (self reported)	22.8	52.4	102.0	-1.7	-10.1
Blood Red Count	12.7	122.7	139.2	-11.8	-10.3
Happiness	11.7	14.2	15.3	3.9	3.6
Comparative height size at age 10	8.0	44.2	49.3	6.3	7.0
Pulse wave reflection index	7.5	9.3	12.9	-2.4	-3.6
Coronary Artery Disease (CAD)	6.5	7.8	9.1	3.0	2.5
Sitting height	6.3	44.8	45.8	6.8	6.6
Hair/balding pattern: Pattern 3	6.2	9.2	12.7	3.6	2.4
Had major operations	6.2	7.3	8.2	-2.5	-2.9
Peak expiratory flow (PEF)	5.5	12.7	20.0	4.5	2.3
Leg predicted mass (left)	5.3	28.2	32.8	4.9	5.7
Leg fat-free mass (left)	5.2	27.4	31.8	4.8	5.6
Financial situation satisfaction	5.2	6.4	6.6	2.6	2.5
Forced expiratory volume in 1-second (FEV1), Best measure	5.1	16.3	22.2	4.7	3.2
Primary Biliary Cirrhosis	5.0	7.1	7.8	2.8	2.5
Leg fat-free mass (right)	5.0	27.0	31.6	4.7	5.6
Leg predicted mass (right)	5.0	26.4	30.9	4.7	5.6
Forced expiratory volume in 1-second (FEV1), predicted	4.9	10.2	12.9	3.6	2.7
Bipolar Disorder (2011)	4.8	4.6	5.3	2.3	2.0
Ever had stillbirth, spontaneous miscarriage or termination	4.8	5.1	7.9	2.8	1.5
Forced expiratory volume in 1-second (FEV1)	4.7	15.8	20.9	4.6	3.3
Weight	4.6	22.8	24.8	4.6	5.0
HDL Cholesterol	4.4	7.4	7.5	2.7	2.7
Standing height	4.4	43.2	45.8	6.4	6.8
Bipolar Disorder (2018)	4.3	6.8	7.2	2.7	2.5
Friendships satisfaction	4.3	5.3	5.7	2.4	2.2
Maternal smoking around birth	4.2	6.1	7.4	2.2	2.7
Trunk fat mass	4.2	18.2	20.0	4.1	4.5
Myopia	4.2	6.1	8.4	-1.9	-2.9
Height	4.1	78.9	89.3	8.3	9.4
Family relationship satisfaction	4.1	5.1	5.2	2.2	2.3
Basal metabolic rate	4.1	22.6	25.0	4.5	5.0
Hearing difficulty/problems with background noise	4.0	6.5	6.6	-2.6	-2.5
Emphysema/chronic bronchitis	3.8	4.3	4.5	-2.1	-2.0
Whole body fat mass	3.8	15.8	17.2	3.8	4.2
Whole body fat-free mass	3.8	21.9	24.5	4.4	4.9
Whole body water mass	3.7	20.9	23.6	4.3	4.9
Headache pain in last month	3.6	6.2	8.2	-2.9	-2.0
Illnesses of siblings: Diabetes	3.6	4.4	5.4	-1.8	-2.3
Hearing aid user	3.6	4.1	4.9	-2.2	-1.8
Arm predicted mass (right)	3.5	17.9	20.5	3.9	4.5
Forced vital capacity (FVC)	3.4	13.2	18.2	4.3	2.9
Arm fat-free mass (right)	3.4	17.6	19.7	3.9	4.4
Number of operations (self-reported)	3.4	5.1	5.5	-2.4	-2.1
Lung FEV1/FVC ratio	3.3	16.7	19.5	3.7	4.4
Qualifications: A levels/AS levels or equivalent	3.3	7.2	8.5	2.9	2.4
Miserableness	3.2	5.6	5.8	2.3	2.4
Forced vital capacity (FVC), Best measure	3.1	11.5	16.4	4.1	2.6
Mother’s age at death	3.1	3.9	4.4	-1.8	-2.1
Trunk fat percentage	3.0	11.9	13.2	3.2	3.6
Trunk predicted mass	3.0	17.4	18.9	4.0	4.3
Breast cancer (self-reported)	3.0	3.6	3.8	-2.0	-1.9
Arm predicted mass (left)	3.0	15.3	16.9	3.7	4.1
Medication: Metformin	2.9	4.1	5.2	-2.3	-1.7
Trunk fat-free mass	2.9	16.6	17.9	3.9	4.2
Arm fat-free mass (left)	2.9	14.7	16.2	3.6	4.0
Leg fat mass (right)	2.8	10.9	11.0	3.3	3.3
Noisy workplace	2.7	3.4	3.5	-1.9	-1.8
Arm fat mass (left)	2.7	11.2	12.7	3.1	3.6
Heel T-Score	2.6	20.3	23.1	-4.8	-4.2
Chronotype (morning person)	2.6	6.0	6.4	2.5	2.4
Time employed in main current job	2.6	3.0	3.8	-1.9	-1.5
Arm fat mass (right)	2.6	10.5	11.8	3.0	3.4
Medication: Omeprazole	2.6	3.1	4.8	-1.2	-2.2
Supplements: Calcium	2.6	2.8	5.0	-2.2	-0.8
Leg fat mass (left)	2.6	10.2	10.8	3.1	3.3
Wears glasses or contact lenses	2.5	2.9	4.0	-1.3	-2.0
Taking other prescription medications	2.4	3.6	6.3	-1.0	-2.5
Tinnitus: Yes, now most or all of the time	2.3	2.6	3.8	-1.2	-2.0
Medication: Blood pressure	2.3	4.3	5.3	1.8	2.3
Severe depression (siblings)	2.2	2.5	3.7	1.9	1.1
Ever unenthusiastic/disinterested for a whole week	2.2	2.7	3.7	1.9	1.3
Medication: Omeprazole (e.g. Zanprol)	2.2	2.6	4.2	-1.0	-2.1
Major Depression (MDD)	2.1	2.6	2.9	1.5	1.7
Hair Pigment	2.1	59.4	96.0	-4.8	-9.8
Hearing difficulty/problems: Yes	2.1	3.2	4.6	-1.3	-2.1
Prospective memory result	2.1	2.6	3.7	1.2	1.9
Body fat percentage	2.1	8.4	8.9	2.8	3.0
Medication for cholesterol	2.1	3.2	3.7	-1.6	-1.9
Age started oral contraceptive pill	2.1	2.7	3.1	-1.5	-1.8
Medication: Allopurinol	2.0	2.7	3.1	1.8	1.5
Fed-up feelings	1.9	3.5	4.6	1.5	2.1
Breast Cancer	1.8	4.4	5.1	2.3	1.9
Pulse wave peak to peak time	1.8	2.2	3.6	0.9	1.9
Neck or shoulder pain in last month	1.8	2.5	3.5	1.9	1.2
Ever had bowel cancer screening	1.8	2.1	3.4	-0.8	-1.9
Ever taken oral contraceptive pill	1.8	2.0	2.8	-1.7	-1.1
Number of incorrect matches in round	1.7	2.9	3.0	1.7	1.7
Diabetes (self-reported)	1.7	2.6	3.0	-1.7	-1.5
Bipolar Disorder or Schizophrenia	1.6	3.8	3.9	2.0	1.9
Ever used hormone-replacement therapy (HRT)	1.6	2.0	2.0	-1.4	-1.4
Vitamin and mineral supplements	1.6	2.2	3.2	-1.8	-1.1
Diabetes (mother)	1.6	2.1	2.4	-1.6	-1.3
Pulse wave Arterial Stiffness index	1.6	1.8	3.1	-0.8	-1.8
Age at last live birth	1.6	2.3	3.4	-1.1	-1.8
Illnesses of father: Heart disease	1.6	2.2	4.2	2.1	0.3
Arm fat percentage (left)	1.6	6.4	7.3	2.3	2.7
Irritable Bowel Disease (IBD)	1.5	3.7	3.8	2.0	1.9
Blood Eosinophil Count	1.5	11.7	19.2	-4.4	-2.0
Age when periods started (menarche)	1.5	3.5	5.3	-2.3	-1.3
Had menopause	1.5	1.9	2.5	1.6	1.2
Heart attack	1.5	1.9	2.1	1.5	1.3
Arm fat percentage (right)	1.5	5.9	6.6	2.3	2.6
Medication for pain relief, constipation, heartburn	1.5	2.6	2.8	1.7	1.5
Medication: Aspirin	1.5	2.0	2.1	-1.3	-1.5
Depressed Affect (Nagel 2018)	1.4	3.0	4.3	1.3	2.1
Neuroticism	1.4	3.3	3.8	1.7	1.9
Average weekly fortified wine intake	1.4	1.7	3.2	-1.8	0.3
Neuroticism score	1.4	3.0	3.6	1.5	1.9
Breastfed as a baby	1.4	1.8	3.2	-0.6	-1.8
Qualifications: NVQ or HND or HNC or equivalent	1.4	1.7	2.7	0.8	1.7
Diabetes diagnosed by doctor	1.4	2.2	2.7	-1.6	-1.3
Back pain experienced in last month	1.4	2.0	3.5	0.7	1.9
Deep venous thrombosis (DVT) (self-reported)	1.4	1.8	2.0	1.4	1.2
Lupus	1.3	2.0	2.3	1.5	1.3
Type 2 Diabetes (T2D) (2012)	1.3	1.5	2.0	-1.0	-1.4
Number of live births	1.3	1.8	2.8	-0.9	-1.7
Chronic bronchitis/emphysema (mother)	1.3	1.6	2.0	-1.4	-1.1
Comparative body size at age 10	1.3	3.5	4.3	1.6	2.1
Medication: Aspirin	1.3	1.7	2.2	-1.1	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.3	1.5	3.0	0.0	-1.7
Mood swings	1.3	2.3	3.7	1.0	1.9
Osteoporosis (self-reported)	1.3	1.6	2.1	-1.1	-1.4
Guilty feelings	1.3	1.9	3.1	1.8	0.8
Heart attack/myocardial infarction (self-reported)	1.3	1.7	1.9	1.4	1.2
Hair/balding pattern: Pattern 4	1.2	2.9	5.8	-0.0	-2.4
Qualifications: College or University degree	1.2	3.9	4.5	-1.8	-2.1
Osteoarthritis (self-reported)	1.2	1.6	2.9	1.7	0.6
Smoking status: Current	1.2	1.9	2.1	1.3	1.4
Pack years adult smoking proportion	1.1	1.6	2.0	1.1	1.4
Lung cancer (father)	1.1	1.3	2.0	-1.4	-0.7
Exposure to tobacco smoke at home	1.1	1.2	2.0	0.6	1.4
Ulcerative Colitis (UC)	1.0	1.9	2.4	1.6	1.2
Body Mass Index (BMI) (2010)	1.0	1.4	1.9	0.9	1.4
Rheumatoid Arthritis	1.0	1.4	2.3	-0.7	-1.5
Ulcerative Colitis	1.0	1.4	2.1	1.4	0.8
Frequency of tenseness / restlessness in last 2 weeks	1.0	1.5	1.7	-1.3	-1.1
Qualifications: O levels/GCSEs or equivalent	1.0	1.6	2.6	1.6	0.7
Blood clot in the leg (DVT)	1.0	1.3	1.6	1.3	1.0
Gout (self-reported)	1.0	1.3	2.2	1.5	0.7
Commuting to job workplace: Walk	1.0	1.0	1.8	-0.5	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.0	2.0	3.2	1.8	0.9
High cholesterol (Self-reported)	1.0	1.8	3.5	-0.0	-1.9
Medication: Paracetamol	1.0	1.6	2.0	-1.1	-1.4
Crohns Disease (2017)	0.9	2.0	2.4	1.3	1.5
Sensitivity / hurt feelings	0.9	1.5	2.4	1.5	0.7
Frequency of depressed mood in last 2 weeks	0.9	1.3	2.1	-1.4	-0.7
Bilateral oophorectomy (both ovaries removed)	0.9	1.1	1.4	0.8	1.2
Body mass index (BMI)	0.9	3.8	4.3	1.8	2.1
Hair/balding pattern: Pattern 2	0.9	1.1	2.0	-1.4	-0.5
Depression (self-reported)	0.9	1.1	1.6	0.7	1.3
Average weekly champagne plus white wine intake	0.9	1.3	2.1	0.7	1.5
Commuting to job workplace: Public transport	0.9	1.0	1.1	1.1	1.0
Irritability	0.9	1.6	2.1	1.1	1.4
LDL Cholesterol	0.8	1.2	1.6	1.3	0.9
Triglycerides	0.8	1.3	1.6	-1.0	-1.2
Hand grip strength (right)	0.8	2.2	4.1	2.0	0.5
Townsend deprivation index at recruitment	0.8	1.1	1.8	0.6	1.3
High blood pressure	0.8	2.3	2.7	1.4	1.6
Waist circumference	0.8	2.8	3.7	1.4	1.9
Allergy	0.8	1.8	2.2	-1.5	-1.2
Illnesses of siblings	0.8	1.1	1.3	0.9	1.1
Hip circumference	0.8	3.5	4.1	1.7	2.0
Asthma	0.8	1.6	2.6	0.8	1.6
Number of children fathered	0.8	0.9	0.9	-1.0	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	1.0	-0.9	-1.0
Eye problems/disorders: None of the above	0.8	1.0	1.2	1.1	0.9
Hypertension (Self-reported)	0.8	2.1	2.3	1.4	1.5
Vascular/heart problems diagnosed by doctor	0.8	2.1	2.6	-1.3	-1.6
Alcohol drinker status: Previous	0.8	0.9	1.4	-1.2	-0.7
BMI	0.7	3.9	4.2	2.0	1.9
Smoking Status	0.7	1.6	2.0	1.4	1.1
Cardiovascular Disease	0.7	2.4	3.4	1.2	1.8
Type 2 Diabetes (T2D) (2018)	0.7	1.3	2.4	-1.6	-0.3
Hand grip strength (left)	0.7	1.8	3.6	1.9	0.3
Number of treatments/medications taken	0.7	1.3	2.0	-0.7	-1.4
Medication: Ramipril	0.7	0.9	1.6	-1.3	-0.5
Medication: Ibuprofen	0.7	0.8	1.1	-1.0	-0.7
Supplements: Vitamin C	0.7	0.8	0.9	0.8	1.0
Asthma (self-reported)	0.7	1.4	2.2	0.7	1.5
Medication: Gliclazide	0.7	0.8	1.0	-1.0	-0.8
Diastolic blood pressure, automated reading	0.7	2.0	3.4	-0.8	-1.8
Pack years of smoking	0.7	1.0	1.1	0.9	1.0
Crohns Disease (2012)	0.6	1.0	1.0	1.0	1.0
Fasting Glucose	0.6	0.7	0.8	0.8	0.9
Hayfever, allergic rhinitis or eczema	0.6	1.2	1.8	1.3	0.8
Supplements: Glucosamine	0.6	0.8	1.4	1.2	0.3
Alcohol usually taken with meals	0.6	0.9	1.2	1.1	0.8
Mouth/teeth dental problems	0.6	0.9	1.3	0.8	1.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.8	0.9	-0.8	-0.9
Leg fat percentage (right)	0.6	2.2	2.5	1.6	1.4
Health satisfaction	0.6	0.8	1.4	1.2	0.4
Overall health rating	0.6	1.2	1.5	1.0	1.2
Schizophrenia (2014)	0.5	1.1	1.1	1.1	1.0
Blood White Count	0.5	3.7	7.1	-2.7	-0.5
Current tobacco smoking	0.5	0.8	1.0	0.8	1.0
Stomach or abdominal pain in last month	0.5	0.7	1.3	0.1	1.1
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	0.7	-0.7	-0.8
Pain all over the body in last month	0.5	0.5	0.9	1.0	-0.4
Fluid intelligence score	0.5	1.1	1.6	1.3	0.8
Pulse rate	0.5	0.9	1.1	0.8	1.1
Medication: Cholesterol lowering	0.5	0.7	1.5	-0.1	-1.2
Medication: Paracetamol	0.5	0.8	0.9	-1.0	-0.9
Glaucoma (self-reported)	0.5	0.6	1.1	0.4	-1.0
Birth weight	0.5	1.0	2.0	0.2	-1.4
Wheeze or whistling in the chest in last year	0.5	0.9	1.2	1.1	0.8
Mouth/teeth dental problems: Loose teeth	0.5	0.5	0.8	-0.9	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	1.0	-0.4	-1.0
Eye problems/disorders: Cataract	0.5	0.6	0.7	-0.8	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.5	0.8	1.6	-0.3	-1.2
Number of self-reported non-cancer illnesses	0.5	0.9	1.8	0.0	-1.4
Medication: Lisinopril	0.5	0.6	0.9	-0.6	-1.0
Average weekly beer plus cider intake	0.5	0.7	1.1	0.5	1.1
Ever depressed for a whole week	0.5	0.6	1.1	1.0	0.4
Neuroticism (Nagel 2018)	0.4	1.0	1.0	1.0	1.0
Ovarian Cancer	0.4	0.5	0.7	0.6	0.8
Average weekly spirits intake	0.4	0.5	1.0	-1.0	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	1.4	-1.2	-0.6
Past tobacco smoking	0.4	0.7	0.9	-0.6	-1.0
Had other major operations	0.4	0.5	0.8	0.5	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	0.6	0.8	0.8
Mouth/teeth dental problems: Dentures	0.4	0.7	0.9	-0.7	-1.0
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.8	-0.3	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.0	0.4	1.0
Chest pain or discomfort	0.4	0.6	0.9	0.5	1.0
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.9	-0.9	-0.4
Leg fat percentage (left)	0.4	1.6	1.7	1.3	1.2
Intelligence (Savage-Jansen 2018)	0.3	1.0	1.5	-0.6	-1.2
Alzheimer’s Disease (including proxy)	0.3	0.4	0.8	0.3	0.9
HbA1C	0.3	0.3	0.7	-0.1	0.8
Waist Hip Ratio (WHR)	0.3	1.3	2.6	-1.6	0.0
Relative age of first facial hair	0.3	0.7	1.0	-0.6	-1.0
Angina	0.3	0.4	0.6	-0.4	0.8
Supplements: Zinc	0.3	0.3	0.5	0.4	-0.7
Impedance of leg (right)	0.3	1.6	2.5	-0.8	-1.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	0.4	-0.7	0.5
Relative age voice broke	0.3	0.4	0.6	-0.5	-0.8
Impedance of leg (left)	0.3	1.6	2.6	-0.8	-1.6
Falls in the last year	0.3	0.4	0.5	0.5	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	0.7	-0.3	0.9
Loud music exposure frequency	0.3	0.4	0.6	-0.3	-0.8
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	0.7	0.5	0.8
Exposure to tobacco smoke outside home	0.3	0.4	0.6	0.8	0.3
Number of full brothers	0.3	0.4	0.7	0.9	-0.1
Angina (self-reported)	0.3	0.4	0.8	-0.2	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	0.4	0.4	0.7
Mineral and other dietary supplements	0.3	0.4	0.6	-0.5	0.8
Illnesses of father: None of the above (group 1)	0.3	0.3	0.7	-0.8	0.1
Illnesses of father: High blood pressure	0.3	0.4	0.6	0.5	0.8
Risk taking	0.3	0.4	0.7	-0.8	-0.4
Basal cell carcinoma (self-reported)	0.3	0.4	0.4	0.7	0.5
Alzheimer’s Disease (in mother)	0.2	0.2	0.4	-0.4	0.6
Neuroticism (2016)	0.2	0.3	0.6	0.8	0.1
Blood Platelet Count	0.2	2.6	3.2	1.8	-1.4
Respiratory disease	0.2	0.3	0.7	-0.8	-0.1
Ever had hysterectomy (womb removed)	0.2	0.2	0.4	0.6	-0.1
Medication for hormone replacement therapy	0.2	0.2	0.2	0.4	0.5
Multivitamins +/- minerals	0.2	0.2	0.3	0.5	-0.4
Medication: Atenolol	0.2	0.2	0.4	0.3	0.6
High blood pressure (mother)	0.2	0.2	0.4	0.6	0.3
Father’s age at death	0.2	0.3	0.6	-0.7	0.1
Worrier / anxious feelings	0.2	0.4	0.4	0.6	0.6
Medication: Lansoprazole	0.2	0.2	0.3	-0.5	-0.3
Illnesses of mother	0.2	0.2	0.2	0.4	0.5
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.3	-0.5	-0.4
Worry too long after embarrassment	0.2	0.3	0.4	0.7	0.3
Age at first live birth	0.2	0.4	0.5	-0.7	-0.6
Shortness of breath walking on level ground	0.2	0.2	0.4	-0.7	0.1
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.4	0.7	0.3
Loneliness, isolation	0.2	0.3	0.5	-0.2	0.7
Long-standing illness, disability or infirmity	0.2	0.4	0.6	0.8	0.4
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.4	0.6	0.3
Supplements: Fish oil (including cod liver oil)	0.2	0.3	0.5	0.3	-0.7
Depression (Nagel 2018)	0.1	0.1	0.2	-0.4	0.3
Schizophrenia (2018)	0.1	0.2	0.2	0.4	0.5
Schizophrenia vs Biploar Disorder	0.1	0.1	0.2	-0.2	0.4
Worry (Nagel 2018)	0.1	0.2	0.5	0.1	-0.7
Reaction Time	0.1	0.3	0.3	0.5	0.6
Age at First Birth	0.1	0.1	0.2	-0.4	-0.3
Lung FVC	0.1	0.7	1.1	0.6	-1.0
Tanning	0.1	1.8	2.4	1.1	1.6
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	0.3	0.4
Serious illness, injury or assault to yourself	0.1	0.1	0.1	0.4	0.2
Chronic bronchitis/emphysema (father)	0.1	0.2	0.3	-0.1	-0.5
Nervous feelings	0.1	0.3	0.5	-0.2	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.5	-0.7	-0.1
Financial difficulties in last 2 years	0.1	0.2	0.4	-0.0	0.6
Alcohol intake versus 10 years previously	0.1	0.2	0.2	0.5	-0.4
Impedance of arm (left)	0.1	0.4	0.5	0.5	0.7
Length of working week for main job	0.1	0.1	0.3	-0.5	0.1
Birth weight of first child	0.1	0.2	0.5	-0.0	-0.7
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.1	-0.3	-0.3
Medication: Amlodipine	0.1	0.1	0.2	-0.5	-0.1
Mean time to correctly identify matches	0.1	0.2	0.3	0.3	0.6
Heart disease (mother)	0.1	0.1	0.1	-0.1	-0.4
Pulse rate, automated reading	0.1	0.3	0.4	0.7	0.4
Alcohol intake frequency.	0.1	0.2	0.3	-0.6	-0.2
Number of full sisters	0.1	0.1	0.1	-0.4	-0.1
Suffer from ‘nerves’	0.1	0.1	0.2	0.4	0.3
Leg pain on walking	0.1	0.1	0.1	-0.3	0.2
Knee pain experienced in last month	0.1	0.2	0.2	0.5	0.3
Smoking status: Previous	0.1	0.1	0.2	0.2	0.4
Average weekly red wine intake	0.1	0.2	0.3	0.2	0.5
Medication: Bendroflumethiazide	0.1	0.1	0.1	0.2	0.3
Alcohol drinker status: Never	0.1	0.1	0.1	0.3	0.3
Ever smoked	0.1	0.2	0.4	0.2	0.6
Fractured/broken bones in last 5 years	0.1	0.2	0.3	-0.1	-0.5
Commuting to job workplace: Cycle	0.1	0.1	0.2	0.4	-0.2
Cholesterol lowering medication	0.1	0.1	0.2	0.5	0.3
Pain experienced in last month	0.1	0.1	0.2	0.0	-0.4
Alzheimer’s Disease (in father)	0.0	0.0	0.0	0.1	-0.0
Verbal and Numeric Reasoning (VNR)	0.0	0.0	0.0	0.2	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Mean Putamen Volume	0.0	0.0	0.0	-0.1	0.1
Systolic Blood Pressure	0.0	0.2	0.4	0.2	0.6
Allergy or Eczema	0.0	0.0	0.1	0.3	-0.0
Other serious medical condition/disability diagnosed by doctor	0.0	0.0	0.0	0.2	0.1
Systolic blood pressure, automated reading	0.0	0.1	0.2	-0.2	-0.5
Medication: Co-codamol	0.0	0.0	0.1	-0.2	-0.1
Diabetes (father)	0.0	0.0	0.0	0.1	0.1
Tinnitus: Yes, but not now, but have in the past	0.0	0.0	0.0	0.0	0.1
Qualifications: CSEs or equivalent	0.0	0.0	0.0	0.2	-0.2
Qualifications: None of the above	0.0	0.1	0.1	-0.2	0.3
Hayfever/allergic rhinitis (self-reported)	0.0	0.0	0.1	0.3	0.1
Medication: Simvastatin	0.0	0.0	0.0	0.0	0.1
Impedance of arm (right)	0.0	0.2	0.3	0.6	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.1	0.1	0.2	-0.2
Tense / ‘highly strung’	0.0	0.0	0.0	0.2	-0.0
High blood pressure (siblings)	0.0	0.1	0.1	0.0	-0.4
Medication: Blood pressure	0.0	0.0	0.0	-0.1	-0.1
Migraine (self-reported)	0.0	0.0	0.0	0.0	-0.2
Medication: Seretide 50 evohaler	0.0	0.0	0.1	-0.2	0.0
Illness, injury, bereavement, stress in last 2 years	0.0	0.0	0.1	-0.2	-0.2
Qualifications: nursing, teaching	0.0	0.1	0.1	0.2	-0.3
Eye problems/disorders: Glaucoma	0.0	0.0	0.1	0.3	-0.2
Medication: Atorvastatin	0.0	0.0	0.0	0.2	-0.2
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	-0.2	-0.1
Unable to work because of sickness or disability	0.0	0.0	0.1	-0.3	0.1
Heart disease (siblings)	0.0	0.0	0.0	-0.1	0.1
Impedance of whole body	0.0	0.0	0.1	0.3	0.0

Hub : Genes

ANP32B

Models

Trait associations