Best TWAS P=4.72e-08 · Best GWAS P=3.33e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LOC100272217 | 0.24 | 0.23 | enet | 16 | 0.24 | 1.7e-28 | 5.1 | 5.3 | 1.4e-07 | 0.98 | 0 | 1.00 | FALSE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | LOC100272217 | 0.28 | 0.12 | lasso | 4 | 0.09 | 9.3e-04 | 5.1 | 5.2 | 1.9e-07 | 1.00 | 0 | 0.94 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | LOC100272217 | 0.07 | 0.02 | blup | 44 | 0.02 | 1.5e-03 | 5.0 | 5.3 | 9.3e-08 | 0.80 | 0 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | LOC100272217 | 0.33 | 0.16 | lasso | 8 | 0.18 | 8.6e-08 | 5.1 | 5.5 | 4.7e-08 | 0.95 | 0 | 1.00 | TRUE |
| 5 | The Cancer Genome Atlas | Soft Tissue Sarcoma | LOC100272217 | 0.09 | 0.05 | enet | 8 | 0.04 | 3.7e-03 | 5.1 | 5.2 | 2.0e-07 | 0.87 | 0 | 0.75 | FALSE |