[Hub]/) : Traits : Blood Red Count : ← →

chr9:129,883,806-132,601,229

Best TWAS P=3.5e-17 · Best GWAS P=6.47e-23 conditioned to 0.000136

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
48	YFS	Blood	ENG	0.06	0.05	lasso	2	0.05	8.9e-16	8.11	-8.4	3.5e-17	-0.63	1.00	0.00	TRUE
27	GTEx	Heart Left Ventricle	RP11-247A12.1	0.14	0.11	lasso	5	0.13	1.7e-07	-6.08	6.9	7.0e-12	0.04	0.02	0.98	TRUE
34	GTEx	Nerve Tibial	RP11-228B15.4	0.09	0.00	enet	22	0.02	2.8e-02	0.25	-5.5	3.0e-08	-0.27	0.12	0.23	TRUE
22	GTEx	Esophagus Mucosa	RP11-247A12.1	0.23	0.13	enet	16	0.16	4.3e-11	-6.38	6.6	5.2e-11	0.00	0.01	0.99	FALSE
43	GTEx	Thyroid	PPP2R4	0.07	0.06	enet	9	0.08	1.0e-06	-6.08	6.6	5.3e-11	0.01	0.02	0.97	FALSE
54	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PPP2R4	0.06	0.05	blup	41	0.08	3.7e-05	-6.11	6.5	6.7e-11	0.03	0.02	0.97	FALSE
70	The Cancer Genome Atlas	Thyroid Carcinoma	CRAT	0.06	0.11	enet	10	0.11	7.1e-11	-6.11	6.5	6.7e-11	0.03	0.02	0.98	FALSE
58	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP2R4	0.03	0.01	blup	40	0.03	2.9e-04	-5.93	6.5	9.2e-11	0.03	0.02	0.94	FALSE
56	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CRAT	0.07	0.08	enet	3	0.10	2.7e-05	-6.11	6.4	1.9e-10	0.02	0.01	0.98	FALSE
19	GTEx	Esophagus Mucosa	CRAT	0.23	0.14	enet	19	0.23	2.1e-15	-6.08	6.4	2.0e-10	0.01	0.02	0.98	FALSE
37	GTEx	Pancreas	RP11-247A12.1	0.27	0.35	lasso	7	0.36	8.4e-16	-6.05	-6.4	2.0e-10	-0.03	0.02	0.98	FALSE
14	GTEx	Colon Transverse	CRAT	0.30	0.26	lasso	3	0.31	1.7e-15	-6.04	6.3	2.4e-10	0.02	0.02	0.98	FALSE
23	GTEx	Esophagus Mucosa	RP11-203J24.9	0.15	0.11	enet	13	0.12	4.2e-08	4.84	-6.3	3.2e-10	-0.34	0.99	0.00	FALSE
52	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PPP2R4	0.08	0.07	enet	8	0.08	2.5e-09	-4.81	6.3	3.7e-10	0.04	0.11	0.89	FALSE
47	YFS	Blood	DOLPP1	0.02	0.00	blup	365	0.01	1.0e-03	4.31	6.2	4.0e-10	-0.02	0.03	0.56	FALSE
6	GTEx	Artery Tibial	CRAT	0.15	0.12	lasso	5	0.10	5.6e-08	-6.13	6.2	4.2e-10	0.04	0.02	0.98	FALSE
69	The Cancer Genome Atlas	Stomach Adenocarcinoma	PPP2R4	0.09	0.10	blup	40	0.09	7.2e-07	-5.93	6.2	4.4e-10	0.04	0.03	0.97	FALSE
53	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CRAT	0.03	0.01	blup	32	0.01	8.9e-03	-5.93	6.2	5.8e-10	0.02	0.02	0.90	FALSE
35	GTEx	Pancreas	CRAT	0.31	0.40	lasso	6	0.43	8.0e-20	-6.05	-6.2	6.4e-10	-0.03	0.02	0.98	FALSE
42	GTEx	Thyroid	CRAT	0.12	0.09	lasso	6	0.09	1.3e-07	-6.08	6.2	6.7e-10	0.03	0.02	0.98	FALSE
60	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	PPP2R4	0.13	0.06	lasso	2	0.06	1.1e-04	-6.08	6.2	7.9e-10	0.02	0.02	0.95	FALSE
26	GTEx	Heart Left Ventricle	CRAT	0.18	0.13	lasso	5	0.14	1.1e-07	-6.05	6.1	8.4e-10	0.03	0.02	0.98	FALSE
39	GTEx	Skin Sun Exposed Lower leg	PPP2R4	0.08	0.03	lasso	4	0.02	8.1e-03	-5.93	6.1	8.5e-10	0.03	0.02	0.97	FALSE
44	GTEx	Whole Blood	CRAT	0.07	0.09	lasso	1	0.08	3.4e-08	-6.13	6.1	8.5e-10	0.03	0.02	0.98	FALSE
18	GTEx	Esophagus Gastroesophageal Junction	CRAT	0.14	0.11	lasso	8	0.06	3.9e-03	-6.04	6.1	9.0e-10	0.02	0.03	0.93	FALSE
59	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CRAT	0.03	0.03	blup	31	0.03	1.6e-04	-6.08	6.1	9.1e-10	0.03	0.02	0.96	FALSE
11	GTEx	Cells Transformed fibroblasts	CRAT	0.23	0.26	lasso	5	0.26	2.1e-19	-6.04	6.1	9.7e-10	0.03	0.02	0.98	FALSE
10	GTEx	Cells EBV-transformed lymphocytes	CRAT	0.17	0.17	lasso	3	0.11	1.6e-04	-6.11	6.1	9.8e-10	0.03	0.02	0.97	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CRAT	0.08	0.08	lasso	1	0.07	7.1e-09	-6.11	6.1	1.0e-09	0.02	0.03	0.97	FALSE
4	GTEx	Artery Aorta	PPP2R4	0.18	0.08	lasso	4	0.09	1.6e-05	-6.09	6.1	1.1e-09	0.02	0.02	0.98	FALSE
5	GTEx	Artery Coronary	CRAT	0.18	0.12	lasso	5	0.12	9.2e-05	-6.11	6.1	1.1e-09	0.03	0.02	0.96	FALSE
7	GTEx	Artery Tibial	PPP2R4	0.14	0.16	lasso	1	0.14	3.0e-11	-6.09	6.1	1.1e-09	0.02	0.02	0.98	FALSE
9	GTEx	Breast Mammary Tissue	PPP2R4	0.11	0.08	lasso	3	0.05	1.9e-03	-6.09	6.1	1.1e-09	0.02	0.02	0.94	FALSE
25	GTEx	Heart Atrial Appendage	CRAT	0.26	0.24	lasso	4	0.25	2.0e-11	-6.11	6.1	1.1e-09	0.03	0.02	0.98	FALSE
45	GTEx	Whole Blood	RP11-247A12.1	0.10	0.03	lasso	6	0.01	1.7e-02	-6.05	6.1	1.1e-09	0.03	0.02	0.94	FALSE
31	GTEx	Muscle Skeletal	RP11-247A12.1	0.08	0.10	lasso	2	0.09	1.9e-09	-6.08	6.1	1.2e-09	0.02	0.02	0.98	FALSE
17	GTEx	Colon Transverse	RP11-247A12.1	0.12	0.10	lasso	4	0.08	9.8e-05	-6.04	6.1	1.3e-09	0.02	0.02	0.97	FALSE
30	GTEx	Muscle Skeletal	CRAT	0.13	0.14	lasso	4	0.13	8.3e-13	-6.08	6.1	1.3e-09	0.02	0.02	0.98	FALSE
33	GTEx	Nerve Tibial	PPP2R4	0.17	0.04	lasso	3	0.03	5.1e-03	-4.81	6.0	1.4e-09	0.04	0.07	0.85	FALSE
3	GTEx	Artery Aorta	CRAT	0.24	0.32	lasso	4	0.31	1.9e-17	-6.04	6.0	1.5e-09	0.02	0.02	0.98	FALSE
68	The Cancer Genome Atlas	Stomach Adenocarcinoma	CRAT	0.07	0.06	blup	29	0.08	3.1e-06	-5.96	6.0	1.6e-09	0.02	0.02	0.98	FALSE
64	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPP2R4	0.03	0.01	blup	43	0.02	1.7e-03	-6.08	6.0	1.7e-09	0.03	0.02	0.91	FALSE
41	GTEx	Stomach	CRAT	0.26	0.10	lasso	7	0.08	1.6e-04	-5.86	6.0	1.8e-09	0.03	0.02	0.96	FALSE
63	The Cancer Genome Atlas	Prostate Adenocarcinoma	CRAT	0.02	0.02	blup	31	0.02	4.5e-03	-6.11	6.0	1.9e-09	0.02	0.02	0.87	FALSE
2	GTEx	Adipose Visceral Omentum	CRAT	0.13	0.09	lasso	9	0.06	5.3e-04	-6.04	6.0	2.0e-09	0.02	0.02	0.96	FALSE
20	GTEx	Esophagus Mucosa	AK1	0.14	0.11	enet	12	0.14	1.7e-09	4.84	-6.0	2.3e-09	-0.34	1.00	0.00	FALSE
66	The Cancer Genome Atlas	Soft Tissue Sarcoma	PPP2R4	0.13	0.11	blup	40	0.10	1.1e-06	-6.08	6.0	2.3e-09	0.02	0.02	0.98	FALSE
29	GTEx	Lung	PPP2R4	0.07	0.03	lasso	3	0.03	3.8e-03	-5.86	6.0	2.6e-09	0.02	0.02	0.97	FALSE
24	GTEx	Esophagus Muscularis	CRAT	0.13	0.09	enet	7	0.11	5.4e-07	-6.13	5.9	2.9e-09	0.03	0.02	0.98	FALSE
57	The Cancer Genome Atlas	Lung Adenocarcinoma	CRAT	0.07	0.08	lasso	4	0.09	3.0e-10	-6.13	5.9	3.0e-09	0.03	0.02	0.98	FALSE
61	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CRAT	0.07	0.05	lasso	1	0.03	2.7e-02	-5.93	5.9	3.1e-09	0.04	0.02	0.61	FALSE
13	GTEx	Colon Sigmoid	PIP5KL1	0.48	0.18	enet	42	0.13	2.6e-05	2.90	5.9	3.2e-09	0.50	0.53	0.35	FALSE
51	The Cancer Genome Atlas	Glioblastoma Multiforme	PPP2R4	0.16	0.04	blup	42	0.08	2.3e-03	-5.43	5.9	3.3e-09	0.02	0.02	0.67	FALSE
55	The Cancer Genome Atlas	Brain Lower Grade Glioma	CRAT	0.03	0.04	blup	31	0.03	1.6e-04	-5.89	5.9	3.6e-09	0.02	0.03	0.97	FALSE
15	GTEx	Colon Transverse	PPP2R4	0.19	0.05	lasso	5	0.09	6.6e-05	-3.19	5.9	4.7e-09	0.00	0.05	0.86	FALSE
67	The Cancer Genome Atlas	Stomach Adenocarcinoma	AK1	0.07	0.03	blup	36	0.05	8.3e-05	6.14	-5.8	5.3e-09	-0.31	0.58	0.04	FALSE
40	GTEx	Spleen	CRAT	0.28	0.28	lasso	2	0.37	2.5e-10	-6.04	5.8	8.5e-09	0.02	0.02	0.96	FALSE
46	YFS	Blood	CRAT	0.13	0.19	enet	27	0.22	2.6e-71	-5.90	5.8	8.8e-09	0.01	0.04	0.96	FALSE
32	GTEx	Nerve Tibial	CRAT	0.14	0.07	lasso	3	0.05	2.6e-04	-5.93	5.7	1.0e-08	0.04	0.02	0.97	FALSE
62	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PPP2R4	0.07	0.04	blup	45	0.03	1.8e-02	-4.73	5.7	1.5e-08	0.02	0.03	0.45	FALSE
8	GTEx	Brain Cerebellum	CRAT	0.35	0.27	lasso	8	0.27	1.1e-08	-5.93	5.6	2.2e-08	0.03	0.03	0.97	FALSE
36	GTEx	Pancreas	DOLPP1	0.14	0.14	lasso	3	0.08	2.7e-04	-5.93	-5.6	2.2e-08	-0.05	0.03	0.96	FALSE
12	GTEx	Cells Transformed fibroblasts	RP11-247A12.1	0.07	0.04	enet	8	0.04	5.0e-04	-4.49	5.5	3.1e-08	0.03	0.04	0.93	FALSE
38	GTEx	Prostate	PPP2R4	0.28	0.00	enet	21	0.01	2.1e-01	3.32	5.5	5.0e-08	0.01	0.04	0.20	FALSE
21	GTEx	Esophagus Mucosa	DOLPP1	0.21	0.18	enet	16	0.19	6.7e-13	-4.49	5.4	5.3e-08	0.02	0.08	0.92	FALSE
65	The Cancer Genome Atlas	Soft Tissue Sarcoma	CRAT	0.10	0.06	blup	28	0.07	6.4e-05	-6.38	5.3	1.3e-07	0.02	0.01	0.98	FALSE
49	The Cancer Genome Atlas	Colon Adenocarcinoma	AK1	0.10	0.03	enet	7	0.03	4.2e-03	-0.95	-5.2	2.5e-07	-0.35	0.08	0.07	FALSE
50	The Cancer Genome Atlas	Esophageal Carcinoma	PPP2R4	0.16	0.11	lasso	3	0.08	1.3e-03	-4.81	5.1	2.7e-07	0.05	0.03	0.41	FALSE
28	GTEx	Liver	PKN3	0.63	0.52	lasso	4	0.50	5.1e-16	5.12	5.1	2.8e-07	0.03	0.82	0.18	FALSE
16	GTEx	Colon Transverse	PKN3	0.37	0.35	lasso	3	0.34	6.2e-17	5.12	5.1	2.9e-07	0.03	0.82	0.18	FALSE