Best TWAS P=1.13e-08 · Best GWAS P=5.73e-11 conditioned to 0.303
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | C10orf11 | 0.24 | 0.21 | lasso | 9 | 0.20 | 3.3e-16 | -4.4 | 5.1 | 2.8e-07 | -0.29 | 0.13 | 0.87 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | C10orf11 | 0.40 | 0.32 | enet | 11 | 0.27 | 2.2e-14 | -4.4 | 5.4 | 6.8e-08 | -0.35 | 0.19 | 0.81 | FALSE |
| 3 | GTEx | Adrenal Gland | C10orf11 | 0.24 | 0.22 | enet | 21 | 0.18 | 5.8e-07 | -4.4 | 5.5 | 4.9e-08 | -0.33 | 0.06 | 0.94 | FALSE |
| 4 | GTEx | Artery Tibial | C10orf11 | 0.26 | 0.17 | enet | 17 | 0.18 | 5.0e-14 | 4.1 | 5.7 | 1.1e-08 | -0.17 | 1.00 | 0.00 | TRUE |
| 5 | ROSMAP | Brain Pre-frontal Cortex | ZNF503-AS2 | 0.07 | 0.06 | lasso | 2 | 0.06 | 2.2e-08 | -5.8 | -5.6 | 2.2e-08 | 0.94 | 0.05 | 0.95 | TRUE |