TWAS hub - ZNF503-AS2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Testis	0.1620	0.0640	0.00560	0.021	NA	0.031	NA	0.059	3.8e-02	NA	1.6e-02	NA	1.3e-03
2	ROSMAP	Brain Pre-frontal Cortex	0.0657	0.0252	0.00032	0.064	0.036	0.057	0.041	0.062	1.2e-08	2e-05	6.5e-08	4.3e-06	2.2e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Impedance of arm (right)	6.9	31.9	37.8	-6.2	-5.1
Pulse wave peak to peak time	6.8	7.9	9.8	2.5	3.1
Arm predicted mass (right)	6.7	34.1	42.6	5.0	6.5
Arm fat-free mass (right)	6.6	33.8	40.1	5.2	6.3
Waist Hip Ratio (WHR)	6.5	29.2	32.0	-5.1	-5.7
Arm fat-free mass (left)	6.3	31.9	40.3	4.8	6.3
Trunk fat-free mass	6.1	34.9	42.1	5.3	6.5
Pulse wave Arterial Stiffness index	6.1	7.1	8.1	-2.5	-2.9
Trunk predicted mass	6.1	34.8	41.6	5.3	6.5
Impedance of whole body	6.1	31.0	38.3	-6.2	-4.9
Arm predicted mass (left)	6.0	30.8	40.4	4.6	6.4
Time employed in main current job	5.8	6.7	7.7	2.8	2.4
Whole body fat-free mass	5.6	32.1	38.6	5.1	6.2
Whole body water mass	5.6	31.8	38.1	5.0	6.2
Hair/balding pattern: Pattern 2	5.5	7.0	11.6	-1.5	-3.4
Impedance of arm (left)	5.4	24.8	28.2	-5.3	-4.6
Comparative body size at age 10	5.3	14.8	21.6	4.7	2.8
Mouth/teeth dental problems: Loose teeth	5.2	6.2	7.0	2.3	2.6
Basal metabolic rate	5.1	28.5	36.5	4.5	6.0
Neuroticism (2016)	4.9	7.1	12.7	1.2	3.6
Age at first live birth	4.8	8.6	12.0	3.5	2.3
Hip circumference	4.7	20.1	27.1	3.6	5.2
Pulse wave reflection index	4.7	5.8	6.6	-2.6	-2.2
Wheeze or whistling in the chest in last year	4.7	8.3	14.1	1.6	3.8
Leg fat-free mass (right)	4.5	24.3	28.0	4.5	5.3
Leg predicted mass (right)	4.5	23.8	27.3	4.5	5.2
Impedance of leg (right)	4.4	21.1	30.8	-5.5	-3.4
Age at last live birth	4.4	6.4	6.7	2.6	2.5
Body Mass Index (BMI) (2010)	4.3	5.9	6.8	2.2	2.6
Leg fat-free mass (left)	4.3	22.6	26.8	4.3	5.2
Leg predicted mass (left)	4.3	22.8	27.6	4.2	5.3
Mean Putamen Volume	4.2	4.7	6.2	1.8	2.5
Impedance of leg (left)	4.2	20.3	28.6	-5.3	-3.5
Migraine (self-reported)	4.1	5.1	6.0	-2.4	-2.1
Medication: Blood pressure	3.6	6.4	9.9	1.7	3.2
Ever had prostate specific antigen (PSA) test	3.6	4.2	7.0	1.2	2.6
Weight	3.5	17.2	26.4	2.8	5.1
Guilty feelings	3.5	5.2	8.2	1.5	2.9
Financial difficulties in last 2 years	3.4	4.6	8.8	0.6	3.0
Loneliness, isolation	3.4	4.7	9.3	0.1	3.0
Medication for cholesterol, blood pressure or diabetes	3.2	5.3	6.1	-2.1	-2.5
Medication: Atorvastatin	3.2	4.0	7.5	0.7	2.7
Average weekly spirits intake	3.1	3.9	7.7	-2.8	-0.2
Hearing difficulty/problems with background noise	3.1	5.0	6.0	-2.0	2.4
Hearing difficulty/problems: Yes	3.0	4.6	7.8	-1.2	2.8
Blood Red Count	2.9	28.2	31.4	-5.0	-5.6
Hair/balding pattern: Pattern 4	2.9	7.0	7.1	2.7	2.6
Eye problems/disorders: Diabetes related eye disease	2.8	3.0	5.5	2.3	-0.8
Commuting to job workplace: Car/motor vehicle	2.8	3.2	4.8	2.2	1.3
Other serious medical condition/disability diagnosed by doctor	2.7	3.6	5.1	-2.2	1.4
Worrier / anxious feelings	2.7	5.2	7.6	1.7	2.8
Illness, injury, bereavement, stress in last 2 years	2.7	3.3	6.2	-0.7	-2.5
Friendships satisfaction	2.6	3.2	6.2	-2.5	-0.4
Happiness	2.5	3.0	3.3	-1.8	1.6
Back pain experienced in last month	2.5	3.7	4.6	1.6	2.1
Sensitivity / hurt feelings	2.4	4.1	6.5	1.3	2.5
Frequency of unenthusiasm / disinterest in last 2 weeks	2.4	3.2	5.9	-0.7	2.4
Diabetes diagnosed by doctor	2.4	3.9	7.9	2.8	0.0
Financial situation satisfaction	2.4	2.9	5.8	0.1	2.4
Depression (Nagel 2018)	2.3	3.5	7.0	0.1	2.6
Frequency of depressed mood in last 2 weeks	2.3	3.3	6.5	0.2	2.6
Body mass index (BMI)	2.3	9.8	15.3	2.1	3.9
Ever had bowel cancer screening	2.3	2.7	5.3	2.3	0.3
Medication: Ramipril	2.2	2.8	5.2	0.6	2.3
Frequency of tiredness / lethargy in last 2 weeks	2.2	3.5	6.7	0.6	2.6
Falls in the last year	2.2	3.0	5.9	-0.4	2.4
Pain type(s) experienced in last month: Hip pain	2.2	2.8	4.5	1.1	2.1
Bipolar Disorder (2018)	2.1	3.2	4.4	-1.5	-2.1
Diabetes (self-reported)	2.1	3.2	6.3	2.5	-0.3
Hair/balding pattern: Pattern 3	2.1	3.1	4.6	1.3	2.1
Leg fat mass (left)	2.1	8.1	13.9	1.5	3.7
Type 2 Diabetes (T2D) (2018)	2.0	3.8	7.0	2.6	-0.8
Diabetes (mother)	2.0	2.5	4.0	1.0	2.0
Supplements: Calcium	2.0	2.2	3.2	1.1	1.8
Type 2 Diabetes (T2D) (2012)	1.9	2.2	2.5	1.6	1.3
Neuroticism	1.9	4.6	8.2	1.0	2.9
Taking other prescription medications	1.9	2.9	5.4	0.7	2.3
Medication: Omeprazole	1.9	2.2	4.5	-2.1	-0.0
Leg fat mass (right)	1.9	7.3	12.9	1.3	3.6
Arm fat mass (left)	1.9	7.9	14.7	1.1	3.8
Ever taken oral contraceptive pill	1.9	2.1	2.5	-1.3	-1.6
Age at First Birth	1.8	2.6	4.3	2.1	0.9
Fasting Glucose	1.8	2.1	2.6	1.3	-1.6
Neuroticism score	1.8	3.7	7.2	0.5	2.7
Arm fat mass (right)	1.8	7.5	14.0	1.0	3.7
Breast cancer (self-reported)	1.8	2.1	3.6	0.8	1.9
Diastolic blood pressure, automated reading	1.8	5.7	8.2	-2.9	-1.8
Commuting to job workplace: Cycle	1.8	2.1	2.9	1.7	-1.2
Deep venous thrombosis (DVT) (self-reported)	1.8	2.3	4.5	-2.1	0.1
BMI	1.7	10.1	12.3	2.8	3.5
Medication for hormone replacement therapy	1.7	1.9	3.3	-0.7	1.8
Frequency of tenseness / restlessness in last 2 weeks	1.7	2.6	5.1	0.4	2.3
Length of working week for main job	1.7	1.9	2.3	1.5	1.2
Forced vital capacity (FVC), Best measure	1.7	6.3	7.4	2.7	2.3
Shortness of breath walking on level ground	1.7	2.0	4.0	-0.0	2.0
Whole body fat mass	1.7	7.2	13.9	0.7	3.7
Schizophrenia vs Biploar Disorder	1.6	2.1	3.8	1.9	0.7
Breast Cancer	1.6	3.9	5.2	1.6	2.3
Lung FVC	1.6	8.0	8.5	2.9	2.7
Current tobacco smoking	1.6	2.6	5.2	0.2	2.3
Stomach or abdominal pain in last month	1.6	2.0	3.5	1.9	0.8
Number of incorrect matches in round	1.6	2.6	4.0	-2.0	-1.1
Depression (self-reported)	1.6	1.9	3.1	-0.8	1.8
Qualifications: O levels/GCSEs or equivalent	1.6	2.6	5.1	2.3	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.8	3.5	-0.4	1.9
Medication: Gliclazide	1.6	1.9	3.2	1.8	-0.7
Smoking status: Current	1.6	2.5	5.1	-0.0	2.3
Ever used hormone-replacement therapy (HRT)	1.5	1.9	2.0	-1.4	1.3
Fed-up feelings	1.5	2.7	5.2	-0.4	2.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.5	2.4	3.4	-1.9	1.1
Neck or shoulder pain in last month	1.5	2.1	2.3	1.4	1.5
Angina (self-reported)	1.5	1.9	3.1	-0.9	1.8
Smoking status: Previous	1.5	2.2	3.8	-0.8	-1.9
Commuting to job workplace: Public transport	1.5	1.8	3.6	-1.9	-0.2
Heart attack/myocardial infarction (self-reported)	1.5	1.9	2.3	1.5	1.2
Serious illness, injury or assault to yourself	1.4	1.7	3.4	0.2	1.8
Fluid intelligence score	1.4	2.8	3.0	1.7	-1.6
Alcohol intake versus 10 years previously	1.4	2.2	3.7	0.8	-1.9
Mouth/teeth dental problems: Dentures	1.4	2.3	2.9	1.7	1.3
Blood clot in the leg (DVT)	1.4	1.8	3.6	-1.9	0.1
Forced expiratory volume in 1-second (FEV1), predicted	1.4	2.8	5.3	0.6	2.3
Long-standing illness, disability or infirmity	1.4	2.2	3.9	-0.7	2.0
Mineral and other dietary supplements	1.4	1.9	3.3	-1.8	-0.7
Pack years of smoking	1.4	2.0	2.3	1.5	1.3
Neuroticism (Nagel 2018)	1.3	3.1	5.8	0.7	2.4
Coronary Artery Disease (CAD)	1.3	1.6	2.1	1.4	1.1
Angina	1.3	1.7	2.8	-0.8	1.7
Supplements: Glucosamine	1.3	1.7	2.4	1.6	1.0
Trunk fat mass	1.3	5.4	10.8	0.2	3.3
Qualifications: A levels/AS levels or equivalent	1.3	3.0	5.3	2.3	0.8
Exposure to tobacco smoke outside home	1.3	1.8	2.0	1.2	1.4
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	2.1	-1.5	-1.0
Supplements: Fish oil (including cod liver oil)	1.3	1.7	3.3	1.8	0.4
Unable to work because of sickness or disability	1.3	1.6	2.8	-1.7	-0.7
Worry (Nagel 2018)	1.2	2.5	4.4	0.8	2.1
Qualifications: None of the above	1.2	2.6	5.1	-2.2	-0.3
Heart attack	1.2	1.5	1.5	1.2	1.2
Noisy workplace	1.2	1.5	2.3	-1.5	-0.8
Ever highly irritable/argumentative for 2 days	1.2	1.4	2.2	-1.5	0.8
Headache pain in last month	1.2	2.0	2.7	-1.1	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.2	1.5	3.1	-0.2	1.8
Health satisfaction	1.2	1.5	3.1	0.0	1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.2	1.4	2.7	-1.6	0.5
Mother’s age at death	1.2	1.5	2.6	0.5	-1.6
Illnesses of father: High blood pressure	1.2	1.5	2.5	0.7	1.6
Fractured/broken bones in last 5 years	1.2	1.5	2.6	0.6	1.6
Pain experienced in last month	1.2	2.0	2.6	-1.2	-1.6
Pack years adult smoking proportion	1.1	1.7	1.8	1.3	1.2
Pain all over the body in last month	1.1	1.1	1.6	1.3	0.8
Medication: Amlodipine	1.1	1.6	3.1	1.8	-0.0
Qualifications: College or University degree	1.1	3.3	6.6	2.6	-0.3
Medication: Seretide 50 evohaler	1.1	1.3	2.2	1.5	0.7
Number of full sisters	1.1	1.3	2.6	-1.6	-0.3
Alcohol drinker status: Never	1.1	1.3	2.7	0.0	1.6
Medication: Co-codamol	1.0	1.1	2.2	1.5	0.3
Medication: Metformin	1.0	1.4	2.8	1.7	0.3
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	2.2	-1.5	0.7
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	1.7	0.8	-1.3
Comparative height size at age 10	1.0	5.3	9.0	1.3	3.0
Had major operations	1.0	1.2	1.8	0.8	-1.3
Age started oral contraceptive pill	1.0	1.2	2.0	0.7	1.4
Major Depression (MDD)	0.9	1.1	1.7	-0.6	1.3
Systolic blood pressure, automated reading	0.9	2.7	3.9	-1.2	-2.0
Diabetes (father)	0.9	1.2	2.3	-0.1	1.5
Sitting height	0.9	6.1	9.2	3.0	1.7
Waist circumference	0.9	3.3	5.5	1.1	2.4
Nervous feelings	0.9	1.8	2.2	-1.5	1.2
Standing height	0.9	8.9	15.0	1.7	3.9
Tense / ‘highly strung’	0.9	1.4	2.0	0.9	1.4
High blood pressure (siblings)	0.9	1.2	2.5	1.6	0.1
Overall health rating	0.9	1.9	3.8	0.3	1.9
Chest pain or discomfort	0.9	1.3	2.2	-0.6	1.5
Medication: Aspirin	0.9	1.1	1.9	1.4	0.6
Ovarian Cancer	0.8	1.1	2.1	-0.2	1.5
HDL Cholesterol	0.8	1.4	2.6	0.4	1.6
Ever had hysterectomy (womb removed)	0.8	0.9	1.7	0.0	-1.3
Medication: Simvastatin	0.8	1.2	2.3	0.1	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	2.9	1.4	1.7
Loud music exposure frequency	0.8	0.9	1.6	0.4	-1.2
Worry too long after embarrassment	0.8	1.4	2.6	0.5	1.6
Emphysema/chronic bronchitis	0.8	0.9	1.8	0.1	1.3
Pulse rate, automated reading	0.8	2.7	4.8	-2.2	-0.8
Family relationship satisfaction	0.8	1.0	2.0	-1.4	0.2
Handedness (chirality/laterality): Left-handed	0.8	0.9	1.2	-1.1	-0.8
Eye problems/disorders: Cataract	0.8	1.0	1.9	1.4	-0.0
Irritability	0.8	1.3	2.5	0.3	1.6
Basal cell carcinoma (self-reported)	0.8	0.9	1.8	-0.2	-1.4
Intelligence (Savage-Jansen 2018)	0.7	2.2	3.8	0.9	-1.9
Blood Platelet Count	0.7	7.6	10.8	3.3	2.1
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	1.5	-0.3	1.2
Past tobacco smoking	0.7	1.2	1.7	0.8	1.3
Forced vital capacity (FVC)	0.7	2.6	3.8	1.9	1.2
Glaucoma (self-reported)	0.7	0.8	0.8	0.9	0.9
Knee pain experienced in last month	0.7	1.0	1.5	-0.7	1.2
Leg fat percentage (left)	0.7	2.4	4.9	-0.0	2.2
Ever depressed for a whole week	0.7	0.8	0.9	-0.9	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	1.8	-1.3	-0.1
Heart disease (siblings)	0.7	0.8	1.2	-1.1	0.7
Triglycerides	0.6	1.1	2.0	-0.4	-1.4
Systolic Blood Pressure	0.6	3.1	5.1	-1.1	-2.3
Trunk fat percentage	0.6	2.6	3.3	-1.4	1.8
Average weekly fortified wine intake	0.6	0.7	1.5	1.2	0.1
Pulse rate	0.6	1.1	1.7	-1.3	0.6
Asthma	0.6	1.2	1.7	0.9	1.3
Peak expiratory flow (PEF)	0.6	1.5	2.8	-1.7	0.4
Birth weight	0.6	1.2	1.9	1.4	0.8
Body fat percentage	0.6	2.3	3.6	-1.0	1.9
Leg fat percentage (right)	0.6	2.2	4.3	-0.2	2.1
Qualifications: nursing, teaching	0.6	1.0	1.8	1.3	0.3
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	1.9	-0.1	1.4
Eye problems/disorders: Glaucoma	0.6	0.7	1.5	1.2	0.1
Medication: Blood pressure	0.6	1.2	1.6	0.9	-1.3
Myopia	0.6	0.9	1.6	0.5	1.3
Depressed Affect (Nagel 2018)	0.5	1.0	2.0	-0.3	1.4
Ulcerative Colitis (UC)	0.5	1.0	1.5	-0.8	-1.2
Schizophrenia (2014)	0.5	1.0	1.9	1.4	0.3
Height	0.5	9.3	17.6	0.9	4.2
Smoking Status	0.5	1.2	1.6	-0.9	1.3
Lung FEV1/FVC ratio	0.5	2.8	4.3	-2.1	-1.1
Hand grip strength (left)	0.5	1.3	2.4	1.6	0.5
Hand grip strength (right)	0.5	1.5	2.9	1.7	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	1.7	-1.3	-0.7
Qualifications: CSEs or equivalent	0.5	0.7	1.2	0.4	1.1
Medication: Atenolol	0.5	0.7	0.9	-0.6	-0.9
Medication: Levothyroxine sodium	0.5	0.8	1.3	-0.6	-1.1
Alcohol usually taken with meals	0.5	0.9	1.4	1.2	-0.5
Had menopause	0.5	0.6	1.2	-0.3	1.1
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	1.0	-0.5	1.0
Number of live births	0.5	0.7	1.2	-1.1	-0.5
Breastfed as a baby	0.5	0.7	0.8	0.9	-0.7
Heart disease (mother)	0.5	0.6	0.9	-0.5	-1.0
Suffer from ‘nerves’	0.5	0.8	0.9	-0.9	0.8
Hypertension (Self-reported)	0.5	1.5	2.8	0.5	1.7
Arm fat percentage (left)	0.5	1.9	3.8	-0.3	1.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.1	1.2	1.1	1.0
Cholesterol lowering medication	0.5	0.7	1.5	-0.2	-1.2
LDL Cholesterol	0.4	0.6	0.9	-0.5	1.0
Primary Biliary Cirrhosis	0.4	0.5	0.5	0.7	-0.7
Age when periods started (menarche)	0.4	0.9	1.1	-0.8	1.0
Had other major operations	0.4	0.5	0.9	0.9	-0.3
Mouth/teeth dental problems	0.4	0.6	0.8	-0.6	-0.9
Arm fat percentage (right)	0.4	1.5	2.4	-0.7	1.6
Father’s age at death	0.4	0.6	0.7	0.6	-0.9
Forced expiratory volume in 1-second (FEV1)	0.4	1.2	1.2	1.1	1.1
Illnesses of mother	0.4	0.5	0.8	-0.9	-0.4
Exposure to tobacco smoke at home	0.4	0.4	0.5	-0.7	0.6
Medication: Paracetamol	0.4	0.7	0.7	-0.8	-0.8
Medication: Ventolin 100micrograms inhaler	0.4	0.5	0.6	0.7	0.7
Average weekly red wine intake	0.4	0.5	0.7	-0.8	0.6
Asthma (self-reported)	0.4	0.8	1.1	0.8	1.0
Medication: Aspirin	0.4	0.5	0.8	0.9	0.4
Medication: Bendroflumethiazide	0.4	0.7	1.0	0.6	1.0
Medication: Paracetamol	0.4	0.6	1.0	-1.0	-0.4
Medication: Lisinopril	0.4	0.5	0.6	0.8	-0.6
Alcohol drinker status: Previous	0.4	0.4	0.8	-0.9	0.3
Schizophrenia (2018)	0.3	0.6	0.9	0.6	0.9
Ulcerative Colitis	0.3	0.5	0.9	-0.2	-0.9
Blood White Count	0.3	2.2	2.3	1.5	1.4
Heel T-Score	0.3	2.6	3.5	-1.3	-1.9
Cardiovascular Disease	0.3	1.1	1.4	1.2	0.9
Maternal smoking around birth	0.3	0.4	0.7	-0.1	0.9
Bilateral oophorectomy (both ovaries removed)	0.3	0.4	0.7	-0.0	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.7	-0.9	0.1
Lung cancer (father)	0.3	0.4	0.6	0.4	0.8
Eye problems/disorders: None of the above	0.3	0.3	0.7	-0.8	0.1
Mean time to correctly identify matches	0.3	0.7	1.2	-0.3	-1.1
Leg pain on walking	0.3	0.3	0.7	-0.2	0.8
Illnesses of siblings: Diabetes	0.3	0.3	0.5	0.3	0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.5	-0.7	0.2
Medication for cholesterol	0.3	0.5	0.9	0.3	0.9
Osteoarthritis (self-reported)	0.3	0.4	0.4	0.6	-0.6
Number of operations (self-reported)	0.3	0.4	0.8	0.9	0.0
Vascular/heart problems diagnosed by doctor	0.3	0.7	1.4	-0.3	-1.2
Alzheimer’s Disease (in mother)	0.2	0.2	0.4	-0.1	0.7
Alzheimer’s Disease (including proxy)	0.2	0.3	0.6	0.2	0.8
Irritable Bowel Disease (IBD)	0.2	0.5	0.5	-0.7	-0.7
Verbal and Numeric Reasoning (VNR)	0.2	0.6	1.1	0.3	-1.0
Blood Eosinophil Count	0.2	1.7	2.5	1.6	0.9
Allergy or Eczema	0.2	0.4	0.7	0.9	0.3
Respiratory disease	0.2	0.4	0.7	0.2	0.8
Tanning	0.2	2.0	2.2	-1.5	-1.3
Number of treatments/medications taken	0.2	0.4	0.5	0.7	0.5
Vitamin and mineral supplements	0.2	0.3	0.6	0.8	-0.1
High blood pressure	0.2	0.6	1.1	0.3	1.0
Multivitamins +/- minerals	0.2	0.3	0.3	-0.5	-0.5
Chronic bronchitis/emphysema (father)	0.2	0.2	0.5	0.2	-0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	1.0	-1.0	0.2
Medication: Cholesterol lowering	0.2	0.3	0.5	-0.4	0.7
Medication: Lansoprazole	0.2	0.3	0.5	0.7	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.3	0.5	0.3	-0.7
Alcohol intake frequency.	0.2	0.4	0.5	-0.7	0.5
Supplements: Vitamin C	0.2	0.2	0.3	0.3	0.5
Mood swings	0.2	0.4	0.8	-0.1	0.9
Osteoporosis (self-reported)	0.2	0.2	0.4	0.6	0.3
Number of self-reported non-cancer illnesses	0.2	0.3	0.5	0.7	0.3
Wears glasses or contact lenses	0.2	0.2	0.4	-0.7	0.1
Hearing aid user	0.2	0.2	0.4	0.2	0.6
Risk taking	0.2	0.3	0.4	-0.5	0.7
Bipolar Disorder or Schizophrenia	0.1	0.2	0.3	-0.4	-0.6
Alzheimer’s Disease (in father)	0.1	0.1	0.1	-0.2	-0.4
Crohns Disease (2017)	0.1	0.2	0.2	-0.5	0.4
Reaction Time	0.1	0.2	0.2	-0.4	-0.5
Prostate Cancer	0.1	0.1	0.1	-0.2	-0.3
Crohns Disease (2012)	0.1	0.2	0.5	-0.7	-0.0
HbA1C	0.1	0.1	0.1	0.1	0.3
Lupus	0.1	0.1	0.1	-0.4	-0.2
Hypothyroidism (self reported)	0.1	0.2	0.4	0.6	0.1
Chronotype (morning person)	0.1	0.2	0.3	0.5	-0.3
Relative age of first facial hair	0.1	0.1	0.1	0.3	0.4
Supplements: Zinc	0.1	0.1	0.1	-0.3	-0.2
Severe depression (siblings)	0.1	0.1	0.2	-0.1	-0.4
Townsend deprivation index at recruitment	0.1	0.2	0.3	-0.0	0.6
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.2	-0.5	-0.2
High blood pressure (mother)	0.1	0.1	0.1	0.3	-0.3
Allergy	0.1	0.1	0.2	0.5	-0.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.2	-0.2	0.5
Prospective memory result	0.1	0.2	0.2	0.3	0.5
Gout (self-reported)	0.1	0.1	0.1	0.3	0.3
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.4	-0.6	-0.3
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.3	0.1	-0.5
Number of children fathered	0.1	0.1	0.2	0.5	0.2
Medication for pain relief, constipation, heartburn	0.1	0.1	0.2	0.1	-0.4
Medication: Allopurinol	0.1	0.1	0.1	-0.3	-0.2
Illnesses of father: Heart disease	0.1	0.1	0.2	-0.4	-0.2
Commuting to job workplace: Walk	0.1	0.1	0.2	-0.1	0.4
Illnesses of father: None of the above (group 1)	0.1	0.1	0.1	0.3	-0.1
Average weekly champagne plus white wine intake	0.1	0.2	0.4	0.6	0.0
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.2	0.4	0.4
High cholesterol (Self-reported)	0.1	0.1	0.2	-0.4	-0.2
Ever smoked	0.1	0.2	0.3	-0.3	-0.6
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	-0.1
Rheumatoid Arthritis	0.0	0.1	0.1	0.1	0.3
Hair Pigment	0.0	0.3	0.3	0.5	-0.6
Relative age voice broke	0.0	0.0	0.0	-0.1	0.2
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.0	0.1	0.2
Illnesses of siblings	0.0	0.0	0.0	-0.0	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.0	0.0	0.0	0.0	0.0
Birth weight of first child	0.0	0.1	0.2	0.0	0.4
Number of full brothers	0.0	0.0	0.1	0.2	-0.2
Medication: Ibuprofen	0.0	0.0	0.0	-0.2	0.2
Miserableness	0.0	0.1	0.1	0.4	0.1
Average weekly beer plus cider intake	0.0	0.0	0.0	-0.1	-0.1

Hub : Genes

ZNF503-AS2

Models

Trait associations