Best TWAS P=3.36e-13 · Best GWAS P=1.4e-14 conditioned to 0.000176
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | DGAT2 | 0.05 | 0.02 | blup | 457 | 0.04 | 1.5e-05 | 6.0 | -5.2 | 2.1e-07 | -0.57 | 0.06 | 0.93 | FALSE |
| 2 | GTEx | Whole Blood | DGAT2 | 0.10 | 0.09 | enet | 5 | 0.09 | 1.6e-08 | 7.1 | -7.1 | 1.5e-12 | -0.69 | 0.32 | 0.68 | FALSE |
| 3 | GTEx | Whole Blood | RP11-535A19.1 | 0.07 | 0.08 | enet | 7 | 0.08 | 1.4e-07 | 7.1 | -7.3 | 3.4e-13 | -0.68 | 0.29 | 0.70 | TRUE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | DGAT2 | 0.05 | 0.04 | blup | 450 | 0.03 | 9.7e-05 | 6.3 | -6.2 | 7.7e-10 | -0.68 | 0.22 | 0.72 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | UVRAG | 0.05 | 0.00 | blup | 144 | 0.01 | 2.4e-02 | 6.0 | 5.8 | 6.6e-09 | 0.60 | 0.03 | 0.81 | FALSE |