TWAS
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Models
Genes
Traits
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Traits
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Blood Red Count
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chr11:77,454,076-78,979,645
Best TWAS P=1.5e-07 · Best GWAS P=3.79e-07 conditioned to 0.442
77.4M
77.6M
77.8M
78M
78.2M
78.4M
78.6M
78.8M
79M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Cerebellar Hemisphere
NARS2
0.17
0.10
lasso
6
0.10
1.5e-03
5.0
-5.2
1.5e-07
-0.91
0.05
0.84
TRUE
2
The Cancer Genome Atlas
Pancreatic Adenocarcinoma
NARS2
0.20
0.21
lasso
9
0.20
5.6e-09
5.0
-5.1
2.8e-07
-0.99
0.02
0.98
FALSE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
NARS2
0.30
0.19
lasso
2
0.17
2.6e-17
5.1
-5.1
2.8e-07
-0.99
0.02
0.98
FALSE