Best TWAS P=1.5e-07 · Best GWAS P=3.79e-07 conditioned to 0.442
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cerebellar Hemisphere | NARS2 | 0.17 | 0.10 | lasso | 6 | 0.10 | 1.5e-03 | 5.0 | -5.2 | 1.5e-07 | -0.91 | 0.05 | 0.84 | TRUE |
2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | NARS2 | 0.20 | 0.21 | lasso | 9 | 0.20 | 5.6e-09 | 5.0 | -5.1 | 2.8e-07 | -0.99 | 0.02 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NARS2 | 0.30 | 0.19 | lasso | 2 | 0.17 | 2.6e-17 | 5.1 | -5.1 | 2.8e-07 | -0.99 | 0.02 | 0.98 | FALSE |