Best TWAS P=4.17e-09 · Best GWAS P=3.45e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PRSS23 | 0.23 | 0.14 | lasso | 4 | 0.13 | 1.5e-07 | 5.9 | 5.9 | 4.2e-09 | 1.00 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Artery Aorta | ME3 | 0.33 | 0.13 | enet | 15 | 0.27 | 5.0e-15 | 5.9 | 5.1 | 2.9e-07 | 0.83 | 0.01 | 0.99 | FALSE |
| 3 | GTEx | Thyroid | ME3 | 0.20 | 0.03 | lasso | 6 | 0.04 | 1.0e-03 | 4.7 | 5.3 | 9.4e-08 | 0.70 | 0.28 | 0.33 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | ME3 | 0.12 | 0.01 | blup | 223 | 0.05 | 4.5e-04 | 4.7 | 5.6 | 2.3e-08 | 0.72 | 0.03 | 0.81 | FALSE |