TWAS
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Usage
Models
Genes
Traits
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Traits
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Blood Red Count
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chr1:117,451,498-118,858,218
Best TWAS P=7.66e-15 · Best GWAS P=3.05e-20 conditioned to 7.96e-10
117.4M
117.6M
117.8M
118M
118.2M
118.4M
118.6M
118.8M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
FAM46C
0.04
0.01
bslmm
394
0.01
0.00068
7.6
-7.8
7.7e-15
-0.50
0.12
0.48
TRUE
1
ROSMAP
Brain Pre-frontal Cortex
FAM46C
0.04
0.00
bslmm
409
0.01
0.04050
-3.1
-5.6
2.7e-08
-0.39
0.04
0.36
FALSE