Best TWAS P=2.37e-12 · Best GWAS P=4.36e-37 conditioned to 2.17e-13
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adrenal Gland | KITLG | 0.27 | -0.01 | enet | 22 | 0.06 | 2.7e-03 | -0.35 | 6.9 | 4.0e-12 | 0.53 | 0.04 | 0.15 | TRUE |
2 | GTEx | Breast Mammary Tissue (Female) | CEP290 | 0.39 | -0.01 | enet | 46 | 0.07 | 4.0e-03 | 5.87 | -6.4 | 1.4e-10 | -0.35 | 0.03 | 0.07 | FALSE |
3 | GTEx | Skin Not Sun Exposed Suprapubic | TMTC3 | 0.35 | 0.05 | enet | 39 | 0.19 | 6.9e-11 | -1.33 | 5.8 | 5.4e-09 | 0.22 | 0.81 | 0.01 | TRUE |
4 | GTEx | Testis | C12orf29 | 0.19 | 0.00 | enet | 24 | 0.00 | 2.4e-01 | 5.34 | 7.0 | 2.4e-12 | 0.46 | 0.03 | 0.46 | TRUE |