Best TWAS P=1.13e-08 · Best GWAS P=1.62e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | C15orf41 | 0.08 | 0.05 | lasso | 4 | 0.04 | 2.0e-06 | 5.6 | -5.6 | 2.2e-08 | -0.98 | 0 | 1.00 | FALSE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C15orf41 | 0.08 | 0.04 | lasso | 3 | 0.04 | 2.1e-05 | 5.5 | -5.4 | 8.5e-08 | -0.96 | 0 | 1.00 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | C15orf41 | 0.06 | 0.06 | lasso | 4 | 0.04 | 6.9e-05 | 5.4 | -5.7 | 1.1e-08 | -0.97 | 0 | 0.99 | TRUE |