Best TWAS P=2.39e-15 · Best GWAS P=6.69e-11 conditioned to 0.000921
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNF280D | 0.07 | 0.00 | bslmm | 407 | 0.04 | 1.4e-05 | 5.2 | -7.9 | 2.4e-15 | 0.45 | 0.07 | 0.35 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | RFX7 | 0.06 | 0.03 | enet | 7 | 0.04 | 2.6e-04 | 5.5 | -6.2 | 6.2e-10 | 0.81 | 0.23 | 0.60 | FALSE |
| 3 | GTEx | Lung | RFX7 | 0.16 | 0.08 | enet | 15 | 0.09 | 4.2e-07 | 4.9 | -5.2 | 1.7e-07 | 0.73 | 0.78 | 0.22 | FALSE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | RFX7 | 0.18 | 0.21 | lasso | 3 | 0.21 | 8.8e-12 | 4.9 | -5.3 | 1.1e-07 | 0.65 | 0.91 | 0.09 | FALSE |
| 5 | GTEx | Testis | RFX7 | 0.32 | 0.28 | lasso | 3 | 0.26 | 9.3e-12 | 4.9 | -5.1 | 2.8e-07 | 0.64 | 0.97 | 0.03 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TEX9 | 0.04 | 0.00 | lasso | 3 | 0.01 | 1.0e-02 | -6.1 | -6.0 | 1.4e-09 | 0.81 | 0.02 | 0.63 | FALSE |