Best TWAS P=3.71e-11 · Best GWAS P=1.26e-08 conditioned to 1.69e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PIAS1 | 0.25 | 0.06 | enet | 38 | 0.13 | 1.0e-10 | -5.4 | -6.6 | 3.7e-11 | -0.23 | 0.08 | 0.91 | TRUE |
| 2 | GTEx | Artery Aorta | PIAS1 | 0.26 | 0.12 | enet | 22 | 0.10 | 3.4e-06 | 2.8 | -5.8 | 9.1e-09 | -0.29 | 0.73 | 0.23 | FALSE |
| 3 | METSIM | Adipose | FEM1B | 0.03 | 0.03 | lasso | 1 | 0.02 | 1.8e-04 | -5.7 | 5.7 | 1.5e-08 | 0.08 | 0.01 | 0.98 | FALSE |
| 4 | YFS | Blood | CALML4 | 0.12 | 0.02 | enet | 49 | 0.08 | 1.0e-25 | -3.2 | -5.2 | 1.8e-07 | -0.33 | 0.98 | 0.00 | FALSE |