[Hub]/) : Traits : Blood Red Count :

chr15:71,414,363-73,775,043

Best TWAS P=1.42e-30 · Best GWAS P=6.74e-29 conditioned to 0.0253

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MYO9A 0.06 0.03 lasso 2 0.01 4.7e-02 -10.9 11.0 3.8e-28 -0.95 0.03 0.92 FALSE
2 GTEx Artery Tibial MYO9A 0.07 0.08 enet 11 0.09 2.5e-07 -10.8 10.3 1.1e-24 -0.94 0.07 0.93 FALSE
3 GTEx Brain Cerebellum MYO9A 0.18 0.12 lasso 2 0.06 6.3e-03 -7.3 7.5 8.5e-14 -0.67 0.09 0.27 FALSE
4 GTEx Breast Mammary Tissue MYO9A 0.19 0.02 lasso 8 0.03 9.4e-03 -10.9 11.5 2.2e-30 -0.88 0.02 0.94 TRUE
5 GTEx Cells EBV-transformed lymphocytes MYO9A 0.13 0.08 lasso 3 0.08 1.7e-03 -10.2 10.3 4.6e-25 -0.89 0.42 0.34 FALSE
6 GTEx Cells EBV-transformed lymphocytes CTD-2524L6.3 0.18 0.12 enet 15 0.11 2.3e-04 -9.0 6.6 3.2e-11 -0.73 0.20 0.40 FALSE
7 GTEx Cells Transformed fibroblasts MYO9A 0.06 0.04 lasso 5 0.03 3.8e-03 -9.5 9.1 7.3e-20 -0.93 0.12 0.82 FALSE
8 GTEx Esophagus Mucosa PKM 0.11 0.04 enet 20 0.06 6.4e-05 -10.4 -8.1 7.5e-16 0.77 0.08 0.91 FALSE
9 GTEx Lung PARP6 0.09 0.03 lasso 5 0.01 8.1e-02 -11.2 -9.7 3.1e-22 0.96 0.02 0.96 FALSE
10 GTEx Nerve Tibial MYO9A 0.13 0.13 lasso 3 0.11 2.1e-08 -11.2 11.5 1.4e-30 -0.97 0.00 1.00 FALSE
11 GTEx Nerve Tibial PARP6 0.09 0.07 lasso 11 0.06 7.2e-05 -5.8 -5.8 6.1e-09 0.21 0.47 0.20 FALSE
12 GTEx Pituitary BBS4 0.27 0.02 enet 21 0.05 2.1e-02 -4.0 -6.3 2.2e-10 0.39 0.09 0.08 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic ADPGK 0.10 0.01 lasso 3 0.02 2.3e-02 -5.0 -5.8 4.8e-09 0.34 0.13 0.06 FALSE
14 GTEx Skin Sun Exposed Lower leg PKM 0.05 0.06 lasso 6 0.05 3.9e-05 -9.4 -9.2 3.0e-20 0.92 0.28 0.71 FALSE
15 GTEx Skin Sun Exposed Lower leg CTD-2524L6.3 0.07 0.01 lasso 3 0.01 1.1e-01 -9.3 7.4 1.0e-13 -0.71 0.09 0.27 FALSE
16 GTEx Stomach MYO9A 0.17 0.06 lasso 5 0.01 1.1e-01 -10.2 9.8 1.6e-22 -0.89 0.21 0.67 FALSE
17 GTEx Testis CTD-2524L6.3 0.10 0.02 enet 13 0.03 2.1e-02 -9.5 9.6 8.4e-22 -0.82 0.08 0.73 FALSE
18 GTEx Thyroid PARP6 0.23 0.02 enet 21 0.07 9.0e-06 -5.8 -6.6 5.2e-11 0.38 0.83 0.11 FALSE
19 YFS Blood MYO9A 0.02 0.02 lasso 3 0.02 5.3e-08 -9.2 9.3 1.2e-20 -0.92 0.32 0.68 FALSE
20 The Cancer Genome Atlas Breast Invasive Carcinoma HEXA 0.01 0.01 enet 6 0.02 1.1e-04 -2.8 7.0 2.6e-12 -0.38 0.08 0.11 FALSE
21 The Cancer Genome Atlas Esophageal Carcinoma SENP8 0.30 0.04 enet 22 0.12 1.2e-04 -10.8 7.5 8.9e-14 -0.57 0.00 0.72 FALSE
22 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BBS4 0.05 0.04 lasso 2 0.04 5.4e-05 -6.9 6.8 7.4e-12 -0.43 0.02 0.89 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NR2E3 0.05 0.02 blup 38 0.02 1.5e-03 -9.3 6.0 2.7e-09 -0.70 0.06 0.16 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma BBS4 0.04 0.01 blup 25 0.02 1.8e-03 -5.0 5.5 4.3e-08 -0.33 0.02 0.53 FALSE
25 The Cancer Genome Atlas Brain Lower Grade Glioma NR2E3 0.03 0.06 lasso 1 0.05 3.8e-06 -10.0 10.0 1.3e-23 -0.83 0.00 1.00 FALSE
26 The Cancer Genome Atlas Brain Lower Grade Glioma PKM2 0.06 0.00 enet 11 0.01 3.0e-02 -1.4 -5.8 8.2e-09 0.62 0.01 0.16 FALSE
27 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NR2E3 0.07 0.02 blup 38 0.05 4.4e-03 -10.1 9.4 4.6e-21 -0.80 0.01 0.65 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma BBS4 0.03 0.00 enet 4 0.01 3.7e-02 -6.9 7.4 1.6e-13 -0.48 0.01 0.73 FALSE