Best TWAS P=1.72e-09 · Best GWAS P=1.47e-08 conditioned to 0.468
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Male) | EMP2 | 0.01 | 0.02 | lasso | 1 | 0.12 | 8.1e-04 | 5.5 | -5.5 | 3.1e-08 | -0.87 | 0.02 | 0.71 | FALSE |
| 2 | GTEx | Esophagus Mucosa | RP11-27M24.1 | 0.23 | 0.11 | lasso | 3 | 0.11 | 1.2e-07 | 5.7 | -5.4 | 5.7e-08 | -0.97 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Esophagus Muscularis | RP11-27M24.1 | 0.28 | 0.15 | enet | 5 | 0.10 | 1.3e-06 | 5.7 | -5.7 | 1.4e-08 | -0.99 | 0.00 | 1.00 | FALSE |
| 4 | GTEx | Nerve Tibial | RP11-27M24.1 | 0.34 | 0.20 | enet | 27 | 0.21 | 7.1e-15 | 5.6 | -5.2 | 2.0e-07 | -0.90 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Pancreas | EMP2 | 0.31 | 0.18 | enet | 22 | 0.19 | 2.1e-08 | 5.7 | -5.9 | 3.9e-09 | -0.87 | 0.00 | 1.00 | FALSE |
| 6 | GTEx | Pancreas | RP11-27M24.1 | 0.24 | 0.06 | enet | 10 | 0.05 | 5.4e-03 | 5.7 | -6.0 | 1.7e-09 | -0.88 | 0.01 | 0.98 | TRUE |