Best TWAS P=9.2e-09 · Best GWAS P=3.3e-07 conditioned to 0.92
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PDXDC1 | 0.02 | 0.01 | blup | 30 | 0.01 | 2.2e-03 | -5.1 | 5.7 | 9.2e-09 | -0.88 | 0.01 | 0.71 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | PDXDC1 | 0.25 | 0.12 | enet | 12 | 0.14 | 1.3e-13 | 4.7 | 5.1 | 2.9e-07 | -0.68 | 0.02 | 0.97 | FALSE |